| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jelena Kezic, Paul G McMenami. Differential turnover rates of monocyte-derived cells in varied ocular tissue microenvironments. Journal of leukocyte biology. vol 84. issue 3. 2008-10-28. PMID:18577714. |
in reverse chimeras, a steady accumulation of host cx3cr1(+/gfp) macrophages in the subretinal space of cx3cr1(+/gfp) adult mice suggests that these cells arise from long-term resident microglia and not newly recruited wt donor cells. |
2008-10-28 |
2023-08-12 |
mouse |
| Daniel R Getts, Rachael L Terry, Meghann Teague Getts, Marcus Müller, Sabita Rana, Bimmi Shrestha, Jane Radford, Nico Van Rooijen, Iain L Campbell, Nicholas J C Kin. Ly6c+ "inflammatory monocytes" are microglial precursors recruited in a pathogenic manner in West Nile virus encephalitis. The Journal of experimental medicine. vol 205. issue 10. 2008-10-14. PMID:18779347. |
depletion of "circulating" (gr1(-)(ly6c(lo))cx3cr1(+)) and "inflammatory" (gr1(hi)/ly6c(hi)/ccr2(+)) classical monocytes during infection abrogated the increase in microglia. |
2008-10-14 |
2023-08-12 |
Not clear |
| Maria Cecilia G Marcondes, Caroline M S Lanigan, Tricia H Burdo, Debbie D Watry, Howard S Fo. Increased expression of monocyte CD44v6 correlates with the deveopment of encephalitis in rhesus macaques infected with simian immunodeficiency virus. The Journal of infectious diseases. vol 197. issue 11. 2008-09-04. PMID:18471064. |
at necropsy, multiple markers (cd44v6, ccr2, and ccr5 on blood monocytes and brain microglia and/or macrophages, and cx3cr1 on blood monocytes) allowed us to distinguish animals with encephalitis from those without. |
2008-09-04 |
2023-08-12 |
human |
| Robert J Ross, Min Zhou, Defen Shen, Robert N Fariss, Xiaoyan Ding, Christine M Bojanowski, Jingsheng Tuo, Chi-Chao Cha. Immunological protein expression profile in Ccl2/Cx3cr1 deficient mice with lesions similar to age-related macular degeneration. Experimental eye research. vol 86. issue 4. 2008-08-21. PMID:18308304. |
while the retinas of four month old wt and ccl2(-/-) showed minimal immunoreactivity for markers of macrophages and microglia, infiltrates of these mononuclear phagocytic cells were detected in the ccl2(-/-)/cx3cr1(-/-)retinal lesions and a few foci in the cx3cr1(-/-) retina. |
2008-08-21 |
2023-08-12 |
mouse |
| Livio Luongo, Marija Sajic, John Grist, Anna K Clark, Sabatino Maione, Marzia Malcangi. Spinal changes associated with mechanical hypersensitivity in a model of Guillain-Barré syndrome. Neuroscience letters. vol 437. issue 2. 2008-08-18. PMID:18448252. |
the expression of the chemokine cx3cl1 (fractalkine) and its receptor cx3cr1 were also higher in ean than in control dorsal horns suggesting spinal microglia and cx3cl1/cx3cr1 may play a role in the pain-like behaviour. |
2008-08-18 |
2023-08-12 |
rat |
| Jelena Kezic, Heping Xu, Holly R Chinnery, Connor C Murphy, Paul G McMenami. Retinal microglia and uveal tract dendritic cells and macrophages are not CX3CR1 dependent in their recruitment and distribution in the young mouse eye. Investigative ophthalmology & visual science. vol 49. issue 4. 2008-06-24. PMID:18385080. |
retinal microglia and uveal tract dendritic cells and macrophages are not cx3cr1 dependent in their recruitment and distribution in the young mouse eye. |
2008-06-24 |
2023-08-12 |
mouse |
| Jing Chen, Kip M Connor, Lois E H Smit. Overstaying their welcome: defective CX3CR1 microglia eyed in macular degeneration. The Journal of clinical investigation. vol 117. issue 10. 2007-11-27. PMID:17909623. |
overstaying their welcome: defective cx3cr1 microglia eyed in macular degeneration. |
2007-11-27 |
2023-08-12 |
mouse |
| Zhi-Ye Zhuang, Yasuhiko Kawasaki, Ping-Heng Tan, Yeong-Ray Wen, Jing Huang, Ru-Rong J. Role of the CX3CR1/p38 MAPK pathway in spinal microglia for the development of neuropathic pain following nerve injury-induced cleavage of fractalkine. Brain, behavior, and immunity. vol 21. issue 5. 2007-08-31. PMID:17174525. |
snl induced an upregulation of cx3cr1 in spinal microglia that began on day 1, peaked on day 3, and maintained on day 10. |
2007-08-31 |
2023-08-12 |
Not clear |
| Zhi-Ye Zhuang, Yasuhiko Kawasaki, Ping-Heng Tan, Yeong-Ray Wen, Jing Huang, Ru-Rong J. Role of the CX3CR1/p38 MAPK pathway in spinal microglia for the development of neuropathic pain following nerve injury-induced cleavage of fractalkine. Brain, behavior, and immunity. vol 21. issue 5. 2007-08-31. PMID:17174525. |
intrathecal injection of a neutralizing antibody against cx3cr1 suppressed not only mechanical allodynia but also the activation of p38 mapk in spinal microglia following snl. |
2007-08-31 |
2023-08-12 |
Not clear |
| Shan Sun, Hong Cao, Mei Han, Ting-Ting Li, Hai-Li Pan, Zhi-Qi Zhao, Yu-Qiu Zhan. New evidence for the involvement of spinal fractalkine receptor in pain facilitation and spinal glial activation in rat model of monoarthritis. Pain. vol 129. issue 1-2. 2007-05-11. PMID:17123734. |
furthermore, blockade of cx3cr1 significantly suppressed activation of spinal glia, especially microglia, evoked by ma. |
2007-05-11 |
2023-08-12 |
rat |
| Astrid E Cardona, Erik P Pioro, Margaret E Sasse, Volodymyr Kostenko, Sandra M Cardona, Ineke M Dijkstra, Deren Huang, Grahame Kidd, Stephen Dombrowski, RanJan Dutta, Jar-Chi Lee, Donald N Cook, Steffen Jung, Sergio A Lira, Dan R Littman, Richard M Ransohof. Control of microglial neurotoxicity by the fractalkine receptor. Nature neuroscience. vol 9. issue 7. 2006-09-05. PMID:16732273. |
microglia, the resident inflammatory cells of the cns, are the only cns cells that express the fractalkine receptor (cx3cr1). |
2006-09-05 |
2023-08-12 |
mouse |
| Jun Feng Ji, S Thameem Dheen, S Dinesh Kumar, Bei Ping He, Samuel Sam Wah Ta. Expressions of cytokines and chemokines in the dorsal motor nucleus of the vagus nerve after right vagotomy. Brain research. Molecular brain research. vol 142. issue 1. 2006-02-27. PMID:16260063. |
double immunofluorescence analysis showed co-localization of lectin, a marker for microglia with cx3cr1 but not with il-1beta at 14 days following right vagotomy. |
2006-02-27 |
2023-08-12 |
Not clear |
| E Milligan, V Zapata, D Schoeniger, M Chacur, P Green, S Poole, D Martin, S F Maier, L R Watkin. An initial investigation of spinal mechanisms underlying pain enhancement induced by fractalkine, a neuronally released chemokine. The European journal of neuroscience. vol 22. issue 11. 2006-02-07. PMID:16324111. |
spinal fractalkine (cx3cl1) is expressed by sensory afferents and intrinsic neurons, whereas its receptor (cx3cr1) is predominantly expressed by microglia. |
2006-02-07 |
2023-08-12 |
rat |
| Dan Sunnemark, Sana Eltayeb, Maria Nilsson, Erik Wallström, Hans Lassmann, Tomas Olsson, Anna-Lena Berg, Anders Ericsson-Dahlstran. CX3CL1 (fractalkine) and CX3CR1 expression in myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis: kinetics and cellular origin. Journal of neuroinflammation. vol 2. 2005-10-07. PMID:16053521. |
the proposed role for cx3cl1 (fractalkine) in the control of microglia activation and leukocyte infiltration places this chemokine and its receptor cx3cr1 in a potentially strategic position to control key aspects in the pathological events that are associated with development of brain lesions in ms. |
2005-10-07 |
2023-08-12 |
rat |
| Jill A Lindia, Erin McGowan, Nina Jochnowitz, Catherine Abbadi. Induction of CX3CL1 expression in astrocytes and CX3CR1 in microglia in the spinal cord of a rat model of neuropathic pain. The journal of pain. vol 6. issue 7. 2005-09-08. PMID:15993821. |
induction of cx3cl1 expression in astrocytes and cx3cr1 in microglia in the spinal cord of a rat model of neuropathic pain. |
2005-09-08 |
2023-08-12 |
rat |
| Jill A Lindia, Erin McGowan, Nina Jochnowitz, Catherine Abbadi. Induction of CX3CL1 expression in astrocytes and CX3CR1 in microglia in the spinal cord of a rat model of neuropathic pain. The journal of pain. vol 6. issue 7. 2005-09-08. PMID:15993821. |
weak immunoreactivity for the cx3cl1 receptor, cx3cr1, was found in microglia in the spinal cord of either naïve rats or rats with inflammation. |
2005-09-08 |
2023-08-12 |
rat |
| Gail M Verge, Erin D Milligan, Steve F Maier, Linda R Watkins, Gregory S Naeve, Alan C Foste. Fractalkine (CX3CL1) and fractalkine receptor (CX3CR1) distribution in spinal cord and dorsal root ganglia under basal and neuropathic pain conditions. The European journal of neuroscience. vol 20. issue 5. 2004-11-09. PMID:15341587. |
its only receptor, cx3cr1, is expressed by microglia. |
2004-11-09 |
2023-08-12 |
rat |
| Gail M Verge, Erin D Milligan, Steve F Maier, Linda R Watkins, Gregory S Naeve, Alan C Foste. Fractalkine (CX3CL1) and fractalkine receptor (CX3CR1) distribution in spinal cord and dorsal root ganglia under basal and neuropathic pain conditions. The European journal of neuroscience. vol 20. issue 5. 2004-11-09. PMID:15341587. |
by contrast, cx3cr1 was expressed by microglia in the basal state, and the microglial cellular concentration was up-regulated in a regionally specific manner in response to neuropathy. |
2004-11-09 |
2023-08-12 |
rat |
| Dan Sunnemark, Sana Eltayeb, Erik Wallström, Lena Appelsved, Asa Malmberg, Hans Lassmann, Anders Ericsson-Dahlstrand, Fredrik Piehl, Tomas Olsso. Differential expression of the chemokine receptors CX3CR1 and CCR1 by microglia and macrophages in myelin-oligodendrocyte-glycoprotein-induced experimental autoimmune encephalomyelitis. Brain pathology (Zurich, Switzerland). vol 13. issue 4. 2004-01-12. PMID:14655765. |
differential expression of the chemokine receptors cx3cr1 and ccr1 by microglia and macrophages in myelin-oligodendrocyte-glycoprotein-induced experimental autoimmune encephalomyelitis. |
2004-01-12 |
2023-08-12 |
rat |
| Dan Sunnemark, Sana Eltayeb, Erik Wallström, Lena Appelsved, Asa Malmberg, Hans Lassmann, Anders Ericsson-Dahlstrand, Fredrik Piehl, Tomas Olsso. Differential expression of the chemokine receptors CX3CR1 and CCR1 by microglia and macrophages in myelin-oligodendrocyte-glycoprotein-induced experimental autoimmune encephalomyelitis. Brain pathology (Zurich, Switzerland). vol 13. issue 4. 2004-01-12. PMID:14655765. |
cx3cr1 mrna expressing cells were identified as microglia on the basis of their cellular morphology and positive gsa/b4 lectin staining. |
2004-01-12 |
2023-08-12 |
rat |