| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xiaohui Wang, Li Wang, Qianqian Yu, Yunyun Xu, Lei Zhang, Xueling Zhao, Xiuli Cao, Yang Li, Lingmin L. Alterations in the expression of Per1 and Per2 induced by Aβ31-35 in the suprachiasmatic nucleus, hippocampus, and heart of C57BL/6 mouse. Brain research. vol 1642. 2017-05-22. PMID:27021954. |
furthermore, real-time pcr and western blot analysis showed that aβ31-35 altered the expression of the per1 and per2 in the scn, hippocampus and heart. |
2017-05-22 |
2023-08-13 |
mouse |
| Saloua Benmansour, Opeyemi S Adeniji, Anthony A Privratsky, Alan Fraze. Effects of Long-Term Treatment with Estradiol and Estrogen Receptor Subtype Agonists on Serotonergic Function in Ovariectomized Rats. Neuroendocrinology. vol 103. issue 3-4. 2017-05-15. PMID:26159182. |
a second part of this study investigated, using western blot analyses in homogenates from hippocampus, whether these behavioral effects are accompanied by changes in the activation of specific signaling pathways and/or trkb. |
2017-05-15 |
2023-08-13 |
rat |
| Jacqueline A Hubbard, Jenny I Szu, Jennifer M Yonan, Devin K Binde. Regulation of astrocyte glutamate transporter-1 (GLT1) and aquaporin-4 (AQP4) expression in a model of epilepsy. Experimental neurology. vol 283. issue Pt A. 2017-05-05. PMID:27155358. |
we used real-time polymerase chain reaction (rt-pcr), western blot, and immunohistochemical analysis at 1, 4, 7, and 30days after kainic acid-induced status epilepticus (se) to determine hippocampal glial fibrillary acidic protein (gfap, a marker for reactive astrocytes), glt1, and aqp4 expression changes during the development of epilepsy (epileptogenesis). |
2017-05-05 |
2023-08-13 |
mouse |
| Chun-Sheng Ruan, Chun-Rui Yang, Jia-Yi Li, Hai-Yun Luo, Larisa Bobrovskaya, Xin-Fu Zho. Mice with Sort1 deficiency display normal cognition but elevated anxiety-like behavior. Experimental neurology. vol 281. 2017-05-01. PMID:27118371. |
we found that sortilin was up-regulated in neocortex (by 78.3%) and hippocampus (by 111%) of chronically stressed mice as assessed by western blot analysis. |
2017-05-01 |
2023-08-13 |
mouse |
| Hong-Chun Li, Jie Xiao, Yi-Long Huang, Long-Jun Li, Hong Jiang, Li-Xuan Huang, Ting Yang, Ling Yang, Fan L. [Reduction in hypoxia-derived neuroinflammation and dysfunctional glutamate transporters by minocycline may restore hypoxia-injured cognition of neonatal rat]. Sheng li xue bao : [Acta physiologica Sinica]. vol 68. issue 2. 2017-04-28. PMID:27108901. |
inflammatory mediators (iba-1, il-1β, tnf-α and tgf-β1), glutamate transporters (eaat1 and eaat2), total tau and phosphorylated tau (phosphorylation sites: tyr18, thr205, thr231, ser396 and ser404) protein expressions in the hippocampus were detected by western blot 7 d after hypoxic exposure. |
2017-04-28 |
2023-08-13 |
rat |
| Zhen Li, Fang Fang, Yuanyin Wang, Liecheng Wan. Resveratrol protects CA1 neurons against focal cerebral ischemic reperfusion-induced damage via the ERK-CREB signaling pathway in rats. Pharmacology, biochemistry, and behavior. vol 146-147. 2017-04-25. PMID:27143440. |
a western blot analysis revealed that res treatment at 1h before ischemia significantly increased erk1/2 phosphorylation and cyclic-amp response element binding protein (creb) phosphorylation in the ca1 region of the hippocampus, which can be prevented with u0126 pretreatment. |
2017-04-25 |
2023-08-13 |
rat |
| Shuai Zhang, Xueyuan Hu, Wei Guan, Li Luan, Bei Li, Qichao Tang, Honggang Fa. Isoflurane anesthesia promotes cognitive impairment by inducing expression of β-amyloid protein-related factors in the hippocampus of aged rats. PloS one. vol 12. issue 4. 2017-04-21. PMID:28403230. |
protein levels of amyloid precursor protein (app), β-site app cleavage enzyme-1 (bace-1) and aβ42 peptide were analyzed in hippocampal samples by western blot. |
2017-04-21 |
2023-08-13 |
rat |
| Jin-A Park, Joon Ha Park, Ji Hyeon Ahn, Jong-Dai Kim, Moo-Ho Won, Choong-Hyun Le. Age‑dependent increase in the expression of antioxidant‑like protein‑1 in the gerbil hippocampus. Molecular medicine reports. vol 14. issue 4. 2017-04-10. PMID:27511601. |
in the present study, the age‑related change in aop‑1 expression in the hippocampus among young, adult and aged gerbils was compared using western blot analysis and immunohistochemistry. |
2017-04-10 |
2023-08-13 |
Not clear |
| Bo Liu, Fei Li, Jingshan Shi, Danli Yang, Yuanyuan Deng, Qihai Gon. Gastrodin ameliorates subacute phase cerebral ischemia‑reperfusion injury by inhibiting inflammation and apoptosis in rats. Molecular medicine reports. vol 14. issue 5. 2017-04-10. PMID:27748849. |
2,3,5‑triphenyltetrazolium chloride staining was using to measure the infarct volume; morphological alterations were observed by hematoxylin and eosin staining under an optical microscope; apoptosis in the hippocampus and cortex was observed by terminal deoxynucleotidyl transferase dutp nick end labeling staining; and the level of mrna and protein expression was tested by reverse transcription‑quantitative polymerase chain reation and western blot analysis, respectively. |
2017-04-10 |
2023-08-13 |
rat |
| Xinyun Su, Chunhua Wang, Xiuhua Wang, Fang Han, Changjun Lv, Xiuli Zhan. Sweet Dream Liquid Chinese Medicine Ameliorates Learning and Memory Deficit in a Rat Model of Paradoxical Sleep Deprivation through the ERK/CREB Signaling Pathway. Journal of medicinal food. vol 19. issue 5. 2017-03-20. PMID:26870900. |
expression of the c-fos, c-jun, cyclic amp response element binding protein (creb), extracellular signal-regulated protein kinase (erk), mitogen-activated protein kinases (mapk)/erk kinase (mek), and p-creb, p-erk, and p-mek in the hippocampus were also assayed by western blot. |
2017-03-20 |
2023-08-13 |
rat |
| J Lin, L Pang, X L Liu, J Xin. Role of vitacamphore in improving central pro-inflammatory cytokines following transient global ischemia. Journal of biological regulators and homeostatic agents. vol 30. issue 4. 2017-03-16. PMID:28078859. |
elisa and western blot analyses were employed to determine pics and their receptors in the cortex and hippocampus. |
2017-03-16 |
2023-08-13 |
rat |
| Ying-Ying Chen, Li Zhang, Dong-Ling Shi, Xing-Hui Song, Yue-Liang Shen, Ming-Zhi Zheng, Lin-Lin Wan. Resveratrol Attenuates Subacute Systemic Inflammation-Induced Spatial Memory Impairment via Inhibition of Astrocyte Activation and Enhancement of Synaptophysin Expression in the Hippocampus. Annals of clinical and laboratory science. vol 47. issue 1. 2017-03-13. PMID:28249911. |
immunohistochemistry and western blot analysis revealed that lps increased hippocampal gfap expression and inhibited synaptophysin expression, which were prevented by resveratrol treatment. |
2017-03-13 |
2023-08-13 |
mouse |
| Jianhui Liu, Yanhong Zhao, Junjun Yang, Xiaoqing Zhang, Wei Zhang, Peijun Wan. Neonatal Repeated Exposure to Isoflurane not Sevoflurane in Mice Reversibly Impaired Spatial Cognition at Juvenile-Age. Neurochemical research. vol 42. issue 2. 2017-03-07. PMID:27882447. |
the hippocampal content of n-methyl-d-aspartate receptor subunits (nmda), brain-derived neurotrophic factor (bdnf), and synaptophysin (syn) were determined by western blot. |
2017-03-07 |
2023-08-13 |
mouse |
| Li Ren, Fan Zhang, Su Min, Xuechao Hao, Peipei Qin, Xianlin Zh. Propofol ameliorates electroconvulsive shock-induced learning and memory impairment by regulation of synaptic metaplasticity via autophosphorylation of CaMKIIa at Thr 305 in stressed rats. Psychiatry research. vol 240. 2017-02-27. PMID:27104927. |
ltp were tested by electrophysiological experiment, the expression of camkiia, p-t305-camkii in hippocampus and camkiiα in hippocampal psd fraction were evaluated by western blot. |
2017-02-27 |
2023-08-13 |
rat |
| Qiang Su, Weiwei Tao, Huang Huang, Yan Du, Xing Chu, Gang Che. Protective effect of liquiritigenin on depressive-like behavior in mice after lipopolysaccharide administration. Psychiatry research. vol 240. 2017-02-27. PMID:27107388. |
the expressions of p65nf-κb, iκbα, brain-derived neurotrophic factor (bdnf) and tropomyosin-related kinase b (trkb) in hippocampus were determined by western blot. |
2017-02-27 |
2023-08-13 |
mouse |
| Yan Feng, Junling Gao, Ying Cui, Minghang Li, Ran Li, Changmeng Cui, Jianzhong Cu. Neuroprotective Effects of Resatorvid Against Traumatic Brain Injury in Rat: Involvement of Neuronal Autophagy and TLR4 Signaling Pathway. Cellular and molecular neurobiology. vol 37. issue 1. 2017-02-13. PMID:26961544. |
in addition, the expression of tlr4 downstream signaling molecules, including myd88, trif, nf-κb, tnf-α, and il-1β, was significantly downregulated in hippocampus tissue by western blot analysis. |
2017-02-13 |
2023-08-13 |
rat |
| Jing Li, Yixin Wang, Fangfang Fang, Donglong Chen, Yue Gao, Jingli Liu, Rong Gao, Jun Wang, Hang Xia. Bisphenol A disrupts glucose transport and neurophysiological role of IR/IRS/AKT/GSK3β axis in the brain of male mice. Environmental toxicology and pharmacology. vol 43. 2017-02-09. PMID:26923231. |
mice were treated with subcutaneous injection of 100μg/kg/d bpa or vehicle for 30 days, then the insulin signaling and glucose transporters in the hippocampus and prefrontal cortex were detected by western blot. |
2017-02-09 |
2023-08-13 |
mouse |
| Mahsima Khoshneviszadeh, Reza Rahimian, Gohar Fakhfouri, Borna Payandemehr, Fariba Khodagholi, Shahram Ejtemaei Mehr, Ahmad Reza Dehpou. Oxytocin is involved in the proconvulsant effects of Sildenafil: Possible role of CREB. Toxicology letters. vol 256. 2017-01-30. PMID:27220266. |
ot release and pcreb expression were evaluated in the hippocampus of mice using elisa and western blot assays, respectively. |
2017-01-30 |
2023-08-13 |
mouse |
| Miguel Ángel Ontiveros-Torres, María Luisa Labra-Barrios, Sofía Díaz-Cintra, Azucena Ruth Aguilar-Vázquez, Samadhi Moreno-Campuzano, Paola Flores-Rodríguez, Claudia Luna-Herrera, Raúl Mena, George Perry, Benjamín Florán-Garduño, José Luna-Muñoz, Juan Pedro Luna-Aria. Fibrillar Amyloid-β Accumulation Triggers an Inflammatory Mechanism Leading to Hyperphosphorylation of the Carboxyl-Terminal End of Tau Polypeptide in the Hippocampal Formation of the 3×Tg-AD Transgenic Mouse. Journal of Alzheimer's disease : JAD. vol 52. issue 1. 2017-01-27. PMID:27031470. |
moreover, we searched for the expression of activated protein kinases and mediators of inflammation by western blot of wholeprotein extracts from hippocampal tissue sections since 3 to 28 months as well. |
2017-01-27 |
2023-08-13 |
mouse |
| Xiaoning Sun, Ning Shi, Ying Li, Chunyan Dong, Maolin Zhang, Zhenhong Guan, Ming Dua. Quantitative Proteome Profiling of Street Rabies Virus-Infected Mouse Hippocampal Synaptosomes. Current microbiology. vol 73. issue 3. 2017-01-26. PMID:27155843. |
synaptosome samples from mice hippocampus were isolated and confirmed by western blot and transmission electron microscopy. |
2017-01-26 |
2023-08-13 |
mouse |