| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mijeong Park, Chong-Hyun Kim, Seonmi Jo, Eun Joo Kim, Hyewhon Rhim, C Justin Lee, Jeansok J Kim, Jeiwon Ch. Chronic Stress Alters Spatial Representation and Bursting Patterns of Place Cells in Behaving Mice. Scientific reports. vol 5. 2016-09-07. PMID:26548337. |
after administering chronic restraint stress (crs; 6 hours/day for ≥21 consecutive days) to adult male mice, several hippocampal characteristics were examined; i.e., spatial learning, in vitro synaptic plasticity, in vivo place cell recording, and western blot analysis to determine protein levels related to learning and memory. |
2016-09-07 |
2023-08-13 |
mouse |
| Wei Chen, Dong An, Hong Xu, Xiaoxin Cheng, Shiwei Wang, Weizhi Yu, Deqin Yu, Dan Zhao, Yiping Sun, Wuguo Deng, Yiyuan Tang, Shengming Yi. Effects of social isolation and re-socialization on cognition and ADAR1 (p110) expression in mice. PeerJ. vol 4. 2016-09-07. PMID:27602277. |
to test our hypothesis, we evaluated the cognition ability of mice isolated for different durations (2, 4, and 8 weeks) using object recognition and object location tests; we also measured adar1 expression in hippocampus and cortex using immunohistochemistry and western blot. |
2016-09-07 |
2023-08-13 |
mouse |
| Amaia M Erdozain, Marina Rubio, J Javier Meana, Javier Fernández-Ruiz, Luis F Callad. Altered CB1 receptor coupling to G-proteins in the post-mortem caudate nucleus and cerebellum of alcoholic subjects. Journal of psychopharmacology (Oxford, England). vol 29. issue 11. 2016-08-26. PMID:26253623. |
the aim of the present study was to evaluate the state of cb1 receptors in post-mortem caudate nucleus, hippocampus and cerebellum of alcoholic subjects.cb1 protein levels were measured by western blot, cb1 receptor density and affinity by [(3)h]win55,212-2 saturation assays and cb1 functionality by [(35)s]gtpγs binding assays. |
2016-08-26 |
2023-08-13 |
human |
| Gaëlle Naert, Valentine Ferré, Johann Meunier, Emeline Keller, Susanna Malmström, Laurent Givalois, François Carreaux, Jean-Pierre Bazureau, Tangui Mauric. Leucettine L41, a DYRK1A-preferential DYRKs/CLKs inhibitor, prevents memory impairments and neurotoxicity induced by oligomeric Aβ25-35 peptide administration in mice. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 25. issue 11. 2016-08-26. PMID:26381812. |
the oxidative stress, apoptotic markers, kinases involved in tau phosphorylation, and synaptic integrity were analyzed by western blot and elisa in the hippocampus. |
2016-08-26 |
2023-08-13 |
mouse |
| C Rozas, C Carvallo, D Contreras, M Carreño, G Ugarte, R Delgado, M L Zeise, B Morale. Methylphenidate amplifies long-term potentiation in rat hippocampus CA1 area involving the insertion of AMPA receptors by activation of β-adrenergic and D1/D5 receptors. Neuropharmacology. vol 99. 2016-08-24. PMID:26165920. |
using field potential recordings and western blot analysis in rat hippocampal slices of young rats, we found that acute application of mph enhances ltp in ca3-ca1 synapses in a dose-dependent manner with an ec50 of 73.44±6.32 nm. |
2016-08-24 |
2023-08-13 |
rat |
| Zhonggui Li, Xiujuan Mi, Yan Xiong, Xin Xu, Xuefeng Wang, Liang Wan. Elevated Expression of the Delta-Subunit of Epithelial Sodium Channel in Temporal Lobe Epilepsy Patients and Rat Model. Journal of molecular neuroscience : MN. vol 57. issue 4. 2016-08-24. PMID:26231936. |
adopting immunohistochemistry, immunofluorescence, and western blot analysis, we found that δ enac was restricted to neurons in the temporal neocortices of tle patients and the cortices and hippocampus of pilocarpine-induced epilepsy rats, which were similar to the corresponding controls. |
2016-08-24 |
2023-08-13 |
human |
| Giovanni Provenzano, Paola Sgadò, Sacha Genovesi, Giulia Zunino, Simona Casarosa, Yuri Bozz. Hippocampal dysregulation of FMRP/mGluR5 signaling in engrailed-2 knockout mice: a model of autism spectrum disorders. Neuroreport. vol 26. issue 18. 2016-08-23. PMID:26559723. |
western blot and immunohistochemistry confirmed the downregulation of fmrp and gabrb3 proteins, while showing a significant increase of mglur5 protein in the en2(-/-) hippocampus. |
2016-08-23 |
2023-08-13 |
mouse |
| Xing-Xing Shi, Bai-Shuang Yin, Peng Yang, Hao Chen, Xin Li, Li-Xue Su, Hong-Gang Fan, Hong-Bin Wan. Xylazine Activates Adenosine Monophosphate-Activated Protein Kinase Pathway in the Central Nervous System of Rats. PloS one. vol 11. issue 4. 2016-08-22. PMID:27049320. |
sprague-dawley rats were sacrificed and the cerebral cortex, cerebellum, hippocampus, thalamus and brainstem were collected for determination of liver kinase b1 (lkb1) and ampkα mrna expression using quantitative real-time polymerase chain reaction (qpcr), and phosphorylated lkb1 and ampkα levels using western blot. |
2016-08-22 |
2023-08-13 |
rat |
| Jin-Fang Ge, Ya-Yun Xu, Ning Li, Yue Zhang, Guo-Liang Qiu, Cheng-Hao Chu, Cai-Yun Wang, Gan Qin, Fei-Hu Che. Resveratrol improved the spatial learning and memory in subclinical hypothyroidism rat induced by hemi-thyroid electrocauterization. Endocrine journal. vol 62. issue 10. 2016-08-17. PMID:26228795. |
the protein expressions of synaptotagmin-1 (syt-1) and brain-derived neurotrophic factor (bdnf) in the hippocampus were measured via western blot. |
2016-08-17 |
2023-08-13 |
rat |
| Yuanyuan Luo, Qiao Hu, Qian Zhang, Siqi Hong, Xiaoju Tang, Li Cheng, Li Jian. Alterations in hippocampal myelin and oligodendrocyte precursor cells during epileptogenesis. Brain research. vol 1627. 2016-08-17. PMID:26433043. |
electroencephalography (eeg), immunofluorescence, and western blot analysis showed that the loss of myelin and oligodendrocytes in the rat hippocampus began during the acute stage of epileptogenesis, and the severity of this loss increased throughout epileptogenesis. |
2016-08-17 |
2023-08-13 |
rat |
| Maryam Sardari, Ameneh Rezayof, Fariba Khodaghol. Hippocampal signaling pathways are involved in stress-induced impairment of memory formation in rats. Brain research. vol 1625. 2016-08-15. PMID:26301822. |
using western blot analysis, it was found that memory retrieval was associated with the increase in the levels of phosphorylated camp-responsive element binding protein (p-creb), peroxisome proliferator-activated receptor gamma coactivator-1α (pgc-1α) and its downstream targets in the hippocampus. |
2016-08-15 |
2023-08-13 |
rat |
| Junhong Zhao, Minghong Sui, Xiao Lü, Dongmei Jin, Zhiqiang Zhuang, Tiebin Ya. Electroacupuncture promotes neural stem cell proliferation and neurogenesis in the dentate gyrus of rats following stroke via upregulation of Notch1 expression. Molecular medicine reports. vol 12. issue 5. 2016-08-15. PMID:26328605. |
reverse transcription quantitative polymerase chain reaction (rt‑qpcr) and western blot analyses were performed to detect the expression levels of notch1 and hes1 in the dentate gyrus (dg) of the hippocampus of rats following mcao. |
2016-08-15 |
2023-08-13 |
rat |
| Weina Li, Changhong Tan, Yi Liu, Xi Liu, Xin Wang, Yuejiang Gui, Lu Qin, Fen Deng, Zhen Yu, Changlin Hu, Lifen Che. Resveratrol ameliorates oxidative stress and inhibits aquaporin 4 expression following rat cerebral ischemia-reperfusion injury. Molecular medicine reports. vol 12. issue 5. 2016-08-15. PMID:26458999. |
inducible nitric oxide synthase (inos) levels in the hippocampus and cortex were measured by elisa, and aquaporin 4 (aqp4) expression was measured by immunohistochemical staining and western blot analysis. |
2016-08-15 |
2023-08-13 |
rat |
| Dae Young Yoo, Ki-Yeon Yoo, Joon Ha Park, Hyun Jung Kwon, Hyo Young Jung, Jong Whi Kim, Goang-Min Choi, Seung Myung Moon, Dae Won Kim, Yeo Sung Yoon, Moo-Ho Won, In Koo Hwan. Time- and cell-type specific changes in iron, ferritin, and transferrin in the gerbil hippocampal CA1 region after transient forebrain ischemia. Neural regeneration research. vol 11. issue 6. 2016-08-02. PMID:27482220. |
western blot analyses supported these results, demonstrating that compared to sham controls, ferritin h and transferrin protein levels in hippocampal homogenates significantly increased at 1 day after ischemia, peaked at 4 days and then decreased. |
2016-08-02 |
2023-08-13 |
Not clear |
| Q Ren, M Ma, C Yang, J-C Zhang, W Yao, K Hashimot. BDNF-TrkB signaling in the nucleus accumbens shell of mice has key role in methamphetamine withdrawal symptoms. Translational psychiatry. vol 5. 2016-07-19. PMID:26506052. |
western blot analysis showed that bdnf levels in the nucleus accumbens (nac) of meth-treated mice were significantly higher than those of control mice whereas bdnf levels in other regions, including the prefrontal cortex and hippocampus, were not altered. |
2016-07-19 |
2023-08-13 |
mouse |
| Jing-jing Le, Tao Yi, Li Qi, Ji Li, Lei Shao, Jing-cheng Don. Electroacupuncture regulate hypothalamic-pituitary-adrenal axis and enhance hippocampal serotonin system in a rat model of depression. Neuroscience letters. vol 615. 2016-07-14. PMID:26773866. |
real-time pcr(rt-pcr)and western blot were respectively used to detect the mrna and protein levels of 5-hydroxytryptamine 1a receptor (5-ht1ar) in the hippocampus. |
2016-07-14 |
2023-08-13 |
rat |
| Rubén García-Cabrerizo, M Julia García-Fuste. Opposite regulation of cannabinoid CB1 and CB2 receptors in the prefrontal cortex of rats treated with cocaine during adolescence. Neuroscience letters. vol 615. 2016-07-14. PMID:26797579. |
this study evaluated cb1 and cb2 protein levels in prefrontal cortex (pfc) and hippocampus (hc) by western blot analysis with specific and validated antibodies: (1) basally during adolescence (post-natal day pnd 40, pnd 47, pnd 54), (2) by a sensitizing regimen of cocaine (15mg/kg, 7 days, i.p.) |
2016-07-14 |
2023-08-13 |
rat |
| Alireza Sarkaki, Yaghoob Farbood, Mohammad Badavi, Leila Khalaj, Fariba Khodagholi, Ghorbangol Ashab. Metformin improves anxiety-like behaviors through AMPK-dependent regulation of autophagy following transient forebrain ischemia. Metabolic brain disease. vol 30. issue 5. 2016-06-24. PMID:25936719. |
autophagy related factors were measured by western blot and immunofluorescent assay in hippocampus of rats. |
2016-06-24 |
2023-08-13 |
rat |
| Dongmei Wang, Junqiang Yan, Jing Chen, Wenlan Wu, Xiaoying Zhu, Yong Wan. Naringin Improves Neuronal Insulin Signaling, Brain Mitochondrial Function, and Cognitive Function in High-Fat Diet-Induced Obese Mice. Cellular and molecular neurobiology. vol 35. issue 7. 2016-06-24. PMID:25939427. |
then the protein levels of insulin signaling pathway and the amp-activated protein kinase (ampk) in the hippocampus were detected by western blot method. |
2016-06-24 |
2023-08-13 |
mouse |
| Sakineh Alijanpour, Ameneh Rezayof, Houri Sepehri, Ladan Delph. Alterations in the hippocampal phosphorylated CREB expression in drug state-dependent learning. Behavioural brain research. vol 292. 2016-06-14. PMID:26055203. |
using western blot analysis, it was found that the p-creb/creb ratio in the hippocampus increased in the mice that showed successful memory retrieval as compared with untrained mice. |
2016-06-14 |
2023-08-13 |
mouse |