| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Luning Sun, Ying Jin, Liming Dong, Hai-Juan Sui, Ryo Sumi, Rabita Jahan, Dahai Hu, Zhi L. Coccomyxa Gloeobotrydiformis Improves Learning and Memory in Intrinsic Aging Rats. International journal of biological sciences. vol 11. issue 7. 2016-03-15. PMID:26078724. |
the following immunohistochemistry and western blot experiments suggested that cgd could increase the content of ach and thereby improve the function of the cholinergic neurons in the hippocampus, and therefore also improving learning and memory ability of the aged rats by acting as an anti-inflammatory agent. |
2016-03-15 |
2023-08-13 |
rat |
| Peter F Weed, Catalin M Filipeanu, Myles J Ketchum, Peter J Winsaue. Chronic Δ9-Tetrahydrocannabinol during Adolescence Differentially Modulates Striatal CB1 Receptor Expression and the Acute and Chronic Effects on Learning in Adult Rats. The Journal of pharmacology and experimental therapeutics. vol 356. issue 1. 2016-03-15. PMID:26462539. |
western blot analysis of brain tissue indicated long-term changes in hippocampal and striatal cannabinoid type-1 receptor (cb1r) levels despite levels that were indistinguishable immediately after chronic treatment during adolescence. |
2016-03-15 |
2023-08-13 |
rat |
| Xiaoqian Zhang, Tingting Liu, Zhike Zhou, Xiaopeng Mu, Chengguang Song, Ting Xiao, Mei Zhao, Chuansheng Zha. Enriched Environment Altered Aberrant Hippocampal Neurogenesis and Improved Long-Term Consequences After Temporal Lobe Epilepsy in Adult Rats. Journal of molecular neuroscience : MN. vol 56. issue 2. 2016-03-14. PMID:25946980. |
western blot was used to measure the expression of sdf-1 and cxcr4 in the hippocampus. |
2016-03-14 |
2023-08-13 |
rat |
| Aiqin Chen, Chengjia Bao, Ying Tang, Xiaoqing Luo, Lixia Guo, Bin Liu, Chun Li. Involvement of protein kinase ζ in the maintenance of hippocampal long-term potentiation in rats with chronic visceral hypersensitivity. Journal of neurophysiology. vol 113. issue 9. 2016-03-07. PMID:25761958. |
furthermore, western blot data showed that the expression of hippocampal phosphorylated pkmζ (p-pkmζ) significantly increased in rats of nms. |
2016-03-07 |
2023-08-13 |
rat |
| Hong Ni, Qi Sun, Tian Tian, Xing Feng, Bao-liang Su. Prophylactic treatment with melatonin before recurrent neonatal seizures: Effects on long-term neurobehavioral changes and the underlying expression of metabolism-related genes in rat hippocampus and cerebral cortex. Pharmacology, biochemistry, and behavior. vol 133. 2016-03-03. PMID:25818576. |
then the protein levels of acat1, cathepsin-e and ca(2+)/calmodulin-dependent protein kinase ii (camk ii) in hippocampus and cerebral cortex were detected by western blot method. |
2016-03-03 |
2023-08-13 |
rat |
| Hong Ni, Qi Sun, Tian Tian, Xing Feng, Bao-liang Su. Prophylactic treatment with melatonin before recurrent neonatal seizures: Effects on long-term neurobehavioral changes and the underlying expression of metabolism-related genes in rat hippocampus and cerebral cortex. Pharmacology, biochemistry, and behavior. vol 133. 2016-03-03. PMID:25818576. |
in parallel with these behavioral changes, gene expression by western blot method demonstrated that rats pretreated with melatonin (mel+rs) showed a significant down-regulated expression of acat-1, cathepsin-e and up-regulated camk ii in hippocampus and cerebral cortex when compared with rs group. |
2016-03-03 |
2023-08-13 |
rat |
| Kazushige Makino, Koji Osuka, Yasuo Watanabe, Nobuteru Usuda, Masahito Hara, Masahiro Aoyama, Masakazu Takayasu, Toshihiko Wakabayash. Increased ICP promotes CaMKII-mediated phosphorylation of neuronal NOS at Ser⁸⁴⁷ in the hippocampus immediately after subarachnoid hemorrhage. Brain research. vol 1616. 2016-03-02. PMID:25940762. |
western blot analysis revealed that nnos phosphorylated (p-nnos) at ser(847) was significantly increased in the hippocampus, but not in the cortex, at 1h after sah compared with that resulting from the control treatment. |
2016-03-02 |
2023-08-13 |
rat |
| Lingpeng Zhu, Tingting Wei, Jing Gao, Xiayun Chang, He He, Mingxing Miao, Tianhua Ya. Salidroside attenuates lipopolysaccharide (LPS) induced serum cytokines and depressive-like behavior in mice. Neuroscience letters. vol 606. 2016-03-01. PMID:26300543. |
levels of neurotransmitters like norepinephrine (ne) and 5-hydroxytryptamine (5-ht) in the prefrontal cortex were detected by hplc-ms. further, brain-derived neurotrophic factor (bdnf), tropomyosin-related kinase b (trkb) and nuclear factor-κb (nf-κb) in hippocampal was determined by western blot analysis. |
2016-03-01 |
2023-08-13 |
mouse |
| Eros Quarta, Riccardo Bravi, Ilaria Scambi, Raffaella Mariotti, Diego Minciacch. Increased anxiety-like behavior and selective learning impairments are concomitant to loss of hippocampal interneurons in the presymptomatic SOD1(G93A) ALS mouse model. The Journal of comparative neurology. vol 523. issue 11. 2016-02-24. PMID:25684566. |
western blot analysis showed that hippocampal parvalbumin expression levels were already reduced in msod1 mice at p56. |
2016-02-24 |
2023-08-13 |
mouse |
| Deng-Xin Zhang, Shan Jiang, Li-Na Yu, Feng-Jiang Zhang, Qing Zhuang, Min Ya. The effect of sevoflurane on the cognitive function of rats and its association with the inhibition of synaptic transmission. International journal of clinical and experimental medicine. vol 8. issue 11. 2016-02-17. PMID:26885010. |
(1) y maze tests were performed, and the expression of syt1 in hippocampal tissues was detected using western blot. |
2016-02-17 |
2023-08-13 |
rat |
| Katarzyna Młyniec, Magdalena Gaweł, Tadeusz Librowski, Witold Reczyński, Beata Bystrowska, Birgitte Hols. Investigation of the GPR39 zinc receptor following inhibition of monoaminergic neurotransmission and potentialization of glutamatergic neurotransmission. Brain research bulletin. vol 115. 2016-02-16. PMID:25917396. |
western blot analysis showed gpr39 up-regulation following 3-day administration of αmt and nmda in the frontal cortex, and gpr39 down-regulation following 10-day administration of pcpa, αmt, and nmda in the hippocampus of cd-1 mice. |
2016-02-16 |
2023-08-13 |
mouse |
| Saju Balakrishnan, Marcus Niebert, Diethelm W Richte. Rescue of Cyclic AMP Mediated Long Term Potentiation Impairment in the Hippocampus of Mecp2 Knockout (Mecp2(-/y) ) Mice by Rolipram. Frontiers in cellular neuroscience. vol 10. 2016-02-12. PMID:26869885. |
western blot analysis of ca region of mecp2 (-/) (y) mice hippocampus revealed more than twofold up-regulation of protein kinase a (pka) regulatory subunits, while the expression of the catalytic subunit remained unchanged. |
2016-02-12 |
2023-08-13 |
mouse |
| Zhi-Hong Hu, Ling-Ling Fan, Yong-Mei H. [Effect of sodium nitrite on phosphorylation of cytoskeletal proteins and spatial learning and memory in rats]. Sheng li xue bao : [Acta physiologica Sinica]. vol 67. issue 5. 2016-02-10. PMID:26490065. |
phosphorylation level of tau and neurofilament, and the expression of protein phosphatase 2a (pp2a) catalytic subunit in the hippocampus were detected by immunohistochemistry and western blot. |
2016-02-10 |
2023-08-13 |
rat |
| Hwayoung Lee, Jaesoon Joo, Seong-Su Nah, Jong Woo Kim, Hyung-Ki Kim, Jun-Tack Kwon, Hwa-Young Lee, Young Ock Kim, Hak-Jae Ki. Changes in Dpysl2 expression are associated with prenatally stressed rat offspring and susceptibility to schizophrenia in humans. International journal of molecular medicine. vol 35. issue 6. 2016-01-25. PMID:25847191. |
western blot analysis and immunohistochemical analysis revealed that the expression of dihydropyrimidinase-like 2 (dpysl2) or collapsin response mediator protein 2 (crmp2) was downregulated in the prefrontal cortex and hippocampus of rats in the pns group. |
2016-01-25 |
2023-08-13 |
human |
| Nali Hou, Xiaofeng Wu, Lan Ren, Min Guo, Yang Bi, Youxue Liu, Jie Chen, Hongmei Haung, Tingyu L. [Acetylated Histone Expressions of the Primary Hippocampal Neurons in Rats Reduced by siCBP Lentivirus]. Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi. vol 32. issue 4. 2016-01-22. PMID:26710457. |
and then we used them to infect the primarily cultured hippocampal neurons, and performed real-time pcr, western blot respectively to detect the expressions of cbp. |
2016-01-22 |
2023-08-13 |
rat |
| Urszula Doboszewska, Bernadeta Szewczyk, Magdalena Sowa-Kućma, Katarzyna Młyniec, Anna Rafało, Beata Ostachowicz, Marek Lankosz, Gabriel Nowa. Antidepressant activity of fluoxetine in the zinc deficiency model in rats involves the NMDA receptor complex. Behavioural brain research. vol 287. 2016-01-20. PMID:25845739. |
the proteins of nmdar (glun1, glun2a and glun2b) or ampar (glua1) subunits, p-creb and bdnf in the hippocampus (western blot) and serum zinc level (txrf) were examined. |
2016-01-20 |
2023-08-13 |
rat |
| Mengying Liu, Xuhong Huangfu, Yangang Zhao, Dongmei Zhang, Jiqiang Zhan. Steroid receptor coactivator-1 mediates letrozole induced downregulation of postsynaptic protein PSD-95 in the hippocampus of adult female rats. The Journal of steroid biochemistry and molecular biology. vol 154. 2016-01-19. PMID:26223010. |
furthermore, when src-1 specific shrna pool was applied to block the expression of src-1 in the primary hippocampal neuron culture, both immunocytochemistry and western blot revealed that levels of psd-95 were also decreased significantly. |
2016-01-19 |
2023-08-13 |
rat |
| Hao Yang, Xiaoxue Zha, Yaojun Cai, Fen Wang, Zhangbi Wu, Bo Wu, Xuemei Jia, Defa Zh. Impacts of thyroxine combined with donepezil on hippocampal ultrastructures and expressions of synaptotagmin-1 and SNAP-25 in adult rats with hypothyroidism. International journal of clinical and experimental medicine. vol 8. issue 10. 2016-01-15. PMID:26770386. |
technique of electron microscope (tem) was used to observe the hippocampal ultrastructures of each group, western blot and real-time rt-pcr were performed to analyze the protein and mrna expressions of syt-1 and snap-25 in the hippocampus of each group. |
2016-01-15 |
2023-08-13 |
rat |
| Sang Hoon Lee, Jee Youn Moon, Sung Jun Jung, Jin Gu Kang, Seung Pyo Choi, Jun Ho Jan. Eugenol inhibits the GABAA current in trigeminal ganglion neurons. PloS one. vol 10. issue 1. 2016-01-13. PMID:25635877. |
rt-pcr and western blot analysis were used to confirm the expression of gabaa receptor γ2 subunit mrna and protein in the tg and hippocampus. |
2016-01-13 |
2023-08-13 |
human |
| Yun-Chieh Tasi, Ting-Yu Chin, Ying-Ju Chen, Chun-Chih Huang, Shou-Lun Lee, Tzong-Yuan W. Potential natural products for Alzheimer's disease: targeted search using the internal ribosome entry site of tau and amyloid-β precursor protein. International journal of molecular sciences. vol 16. issue 4. 2016-01-11. PMID:25903151. |
western blot analysis of the tau protein in neuroblastoma (n2a) and rat hippocampal cells confirmed the halting of the expression of the tau proteins. |
2016-01-11 |
2023-08-13 |
mouse |