| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jin-Il Kim, Seong Gak Jeon, Kyoung Ah Kim, Yong Jun Kim, Eun Ji Song, Junghyun Choi, Kyu Jeung Ahn, Chong-Jin Kim, Ho Yeon Chung, Minho Moon, Hyunju Chun. The pharmacological stimulation of Nurr1 improves cognitive functions via enhancement of adult hippocampal neurogenesis. Stem cell research. vol 17. issue 3. 2017-10-25. PMID:27788475. |
here we used rt-pcr, western blot, and immunocytochemistry to show that adult hippocampal npcs abundantly express nurr1. |
2017-10-25 |
2023-08-13 |
mouse |
| Xu Li, Yubao Chen, Siying Shao, Qing Tang, Weihai Chen, Yi Chen, Xiaoyu X. Oxidative stress induces the decline of brain EPO expression in aging rats. Experimental gerontology. vol 83. 2017-10-16. PMID:27452792. |
the levels of epo, epor, p-jak2 and hypoxia-inducible factor-2α (hif-2α) in the hippocampus were detected by western blot. |
2017-10-16 |
2023-08-13 |
rat |
| Zhao-Xu Zhang, Rui-Ping Zhao, De-Sheng Wang, An-Ning Wan. Fuzhisan ameliorates Aβ production and tau phosphorylation in hippocampal of 11month old APP/PS1 transgenic mice: A Western blot study. Experimental gerontology. vol 84. 2017-10-12. PMID:27612601. |
fuzhisan ameliorates aβ production and tau phosphorylation in hippocampal of 11month old app/ps1 transgenic mice: a western blot study. |
2017-10-12 |
2023-08-13 |
mouse |
| Ming-Rui Zhang, Chao Qu, Jia Sun, Cui Wang, Hong-Yan Li, Ye-Jun Zhang, Bing-Qiang Zhang, Wei Zo. [Different subtypes of estrogen receptor α and related signal molecules in the hippocampus are associated with spatial cognitive impairment of diabetic mice]. Sheng li xue bao : [Acta physiologica Sinica]. vol 69. issue 3. 2017-10-03. PMID:28638916. |
meanwhile, using western blot, we detected the protein expressions of er-α36, er-α66, caveolin-1, pkcα, camp-response element binding protein 2 (creb2), and synaptophysin (syn) in the hippocampus of the mice. |
2017-10-03 |
2023-08-13 |
mouse |
| J J Botterill, N Nogovitsyn, H J Caruncho, L E Kalynchu. Selective plasticity of hippocampal GABAergic interneuron populations following kindling of different brain regions. The Journal of comparative neurology. vol 525. issue 2. 2017-09-29. PMID:27362579. |
long-evans rats received 99 electrical stimulations of the hippocampus, amygdala, or caudate nucleus, followed by sacrifice and immunohistochemical or western blot analyses. |
2017-09-29 |
2023-08-13 |
rat |
| Wei Huang, Zhongyu Zhou, Bijiang Wan, Guang Chen, Jia L. Nuclear Factor kB and Inhibitor of kB: Acupuncture Protection Against Acute Focal Cerebral Ischemia in Rodents. Alternative therapies in health and medicine. vol 23. issue 3. 2017-09-14. PMID:28236616. |
outcome measures • the study (1) evaluated neurological function using the modified neurological severity score; (2) examined the ultrastructure; (3) assessed the infarct volume; (4) determined levels of serum inflammatory cytokines; and (5) measured protein expression in the hippocampus 24 h after mcao using a western blot analysis. |
2017-09-14 |
2023-08-13 |
rat |
| Chenxia Han, Feng Li, Jie Ma, Yan Liu, Weihong Li, Yingqiu Mao, Yuehan Song, Siyuan Guo, Jing Li. Distinct behavioral and brain changes after different durations of the modified multiple platform method on rats: An animal model of central fatigue. PloS one. vol 12. issue 5. 2017-09-11. PMID:28493899. |
corticosterone levels were detected by elisa, and the hippocampal nr1 and nr2a were measured by rt-pcr and western blot analysis. |
2017-09-11 |
2023-08-13 |
rat |
| Yu-Lang Fei, Hong-Jun Lv, Yan-Bo Li, Jie Liu, Yi-Hua Qian, Wei-Na Yang, Kai-Ge Ma, Hong-Bao Li, Qiu-Min Q. Tongxinluo improves cognition by decreasing β-amyloid in spontaneous hypertensive rats. Brain research. vol 1663. 2017-09-05. PMID:28274609. |
moreover, the aβ in the hippocampus significantly decreased compared to the vehicle group, both in western blot and elisa. |
2017-09-05 |
2023-08-13 |
rat |
| Tao Zhang, Jianbo Gu, Liangmiao Wu, Ning Li, Yewei Sun, Pei Yu, Yuqiang Wang, Gaoxiao Zhang, Zaijun Zhan. Neuroprotective and axonal outgrowth-promoting effects of tetramethylpyrazine nitrone in chronic cerebral hypoperfusion rats and primary hippocampal neurons exposed to hypoxia. Neuropharmacology. vol 118. 2017-09-05. PMID:28342896. |
western blot analyses indicated that tbn increased bcl-2 expression, decreased bax and caspase 3 expressions, and upregulated the phosphorylation levels of high-molecular weight neurofilament (p-nfh), akt (p-akt) and glycogen synthase kinase-3β (p-gsk3β) in hippocampus at 6th week after chronic hypoperfusion. |
2017-09-05 |
2023-08-13 |
rat |
| Jun Yamada, Tomohiro Ohgomori, Shozo Jinn. Alterations in expression of Cat-315 epitope of perineuronal nets during normal ageing, and its modulation by an open-channel NMDA receptor blocker, memantine. The Journal of comparative neurology. vol 525. issue 9. 2017-08-25. PMID:28271508. |
western blot analysis showed that the expression levels of cat-315 epitope in the hippocampus were higher in middle-aged (ma, 12-month-old) mice than in young adult (ya, 2-month-old) mice. |
2017-08-25 |
2023-08-13 |
mouse |
| Lili Jia, Fei Wang, Xiangqian Gu, Yiqi Weng, Mingwei Sheng, Gang Wang, Shipeng Li, Hongyin Du, Wenli Y. Propofol postconditioning attenuates hippocampus ischemia-reperfusion injury via modulating JAK2/STAT3 pathway in rats after autogenous orthotropic liver transplantation. Brain research. vol 1657. 2017-08-07. PMID:27998796. |
we evaluated histological damage, inflammation, oxidative stress and apoptosis in hippocampus using he staining, light microscope, real-time pcr and western blot. |
2017-08-07 |
2023-08-13 |
rat |
| Gabriela Hurtado-Alvarado, Emilio Domínguez-Salazar, Javier Velázquez-Moctezuma, Beatriz Gómez-Gonzále. A2A Adenosine Receptor Antagonism Reverts the Blood-Brain Barrier Dysfunction Induced by Sleep Restriction. PloS one. vol 11. issue 11. 2017-08-01. PMID:27893847. |
in addition, we evaluated by western blot the expression of tight junction proteins (claudin-5, occludin, zo-1), adherens junction protein (e-cadherin), a2a adenosine receptor, adenosine-synthesizing enzyme (cd73), and neuroinflammatory markers (iba-1 and gfap) in the cerebral cortex, hippocampus, basal nuclei and cerebellar vermis. |
2017-08-01 |
2023-08-13 |
rat |
| Rui Zhang, Huimin Zhou, Lei Jiang, Yueran Mao, Ximing Cui, Bing Xie, Dongsheng Cui, Hui Wang, Qingfu Zhang, Shunjiang X. MiR-195 dependent roles of mitofusin2 in the mitochondrial dysfunction of hippocampal neurons in SAMP8 mice. Brain research. vol 1652. 2017-07-28. PMID:27693395. |
the results of quantitative real-time pcr and western blot revealed that mfn2 expression displayed a consistent decrease with aging in the hippocampus of samp8 than did age-matched samr1 mice. |
2017-07-28 |
2023-08-13 |
mouse |
| He Huang, Cun-Ming Liu, Jie Sun, Ting Hao, Chun-Mei Xu, Dan Wang, Yu-Qing W. Ketamine Affects the Neurogenesis of the Hippocampal Dentate Gyrus in 7-Day-Old Rats. Neurotoxicity research. vol 30. issue 2. 2017-07-17. PMID:26966008. |
the expression of gfap in the hippocampal dg was measured by western blot analysis. |
2017-07-17 |
2023-08-13 |
rat |
| Hui-Lin Wang, Hua Liu, Zhang-Gang Xue, Qing-Wu Liao, Hao Fan. Minocycline attenuates post-operative cognitive impairment in aged mice by inhibiting microglia activation. Journal of cellular and molecular medicine. vol 20. issue 9. 2017-06-30. PMID:27061744. |
hippocampal tissues were isolated from mice and evaluated by western blot analysis, immunofluorescence procedures and protein array system. |
2017-06-30 |
2023-08-13 |
mouse |
| Michael F Almeida, Carolliny M Silva, Aline M D'Unhao, Merari F R Ferrar. Aged Lewis rats exposed to low and moderate doses of rotenone are a good model for studying the process of protein aggregation and its effects upon central nervous system cell physiology. Arquivos de neuro-psiquiatria. vol 74. issue 9. 2017-06-28. PMID:27706423. |
hyperphosphorylated tau, alpha-synuclein, amyloid-beta peptide and protein carbonylation (indicative of oxidative stress) were evaluated in the hippocampus, substantia nigra and locus coeruleus through immunohistochemistry or western blot. |
2017-06-28 |
2023-08-13 |
rat |
| Xiu Wang, Yao Wang, Chao Zhang, Chang Liu, Baotian Zhao, Naili Wei, Jian-Guo Zhang, Kai Zhan. CB1 receptor antagonism prevents long-term hyperexcitability after head injury by regulation of dynorphin-KOR system and mGluR5 in rat hippocampus. Brain research. vol 1646. 2017-06-22. PMID:27262683. |
then, pcr and western blot showed that sr141716a inhibited the long-term up-regulation of cb1 receptors in hippocampus. |
2017-06-22 |
2023-08-13 |
rat |
| Christian Lange-Asschenfeldt, Sandra Schäble, Tatsiana Suvorava, Ehsan Gholamreza Fahimi, Marion Bisha, Torben Stermann, Uwe Henning, Georg Kojd. Effects of varenicline on alpha4-containing nicotinic acetylcholine receptor expression and cognitive performance in mice. Neuropharmacology. vol 107. 2017-06-21. PMID:27012889. |
protein and mrna expression of both the α4 and β2 receptor subunits in mouse brain endothelial and hippocampal cells as well as hippocampus and neocortex tissues were determined by western blot and realtime pcr, respectively. |
2017-06-21 |
2023-08-13 |
mouse |
| Gustavo Provensi, Alessia Costa, M Beatrice Passani, Patrizio Blandin. Donepezil, an acetylcholine esterase inhibitor, and ABT-239, a histamine H3 receptor antagonist/inverse agonist, require the integrity of brain histamine system to exert biochemical and procognitive effects in the mouse. Neuropharmacology. vol 109. 2017-06-19. PMID:27291828. |
western blot analysis revealed that abt-239 or donepezil systemic treatments increased gsk-3β phosphorylation in cortical and hippocampal homogenates of normal, but not of histamine-depleted mice. |
2017-06-19 |
2023-08-13 |
mouse |
| Shingo Enomoto, Kunio Shimizu, Masashi Nibuya, Hiroyuki Toda, Aihide Yoshino, Eiji Suzuki, Takashi Kondo, Hiroshi Fukud. Increased expression of endocytosis-Related proteins in rat hippocampus following 10-day electroconvulsive seizure treatment. Neuroscience letters. vol 624. 2017-06-06. PMID:27177725. |
in the present report, western blot analyses revealed significantly upregulated expression of various endocytosis-related proteins following 10-day electroconvulsive seizure (ecs) treatment in rat hippocampal homogenates and hippocampal lipid raft fractions extracted using an ultracentrifugation procedure. |
2017-06-06 |
2023-08-13 |
rat |