| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ping Sun, Jun-Bo Yin, Li-Hua Liu, Jian Guo, Sheng-Hai Wang, Chun-Hui Qu, Chun-Xia Wan. Protective role of Dihydromyricetin in Alzheimer's disease rat model associated with activating AMPK/SIRT1 signaling pathway. Bioscience reports. vol 39. issue 1. 2019-07-26. PMID:30498091. |
then, the inflammatory cytokines expressions were determined by radioimmunoassay while expressions of ampk/sirt1 pathway-related proteins by western blot; and the apoptosis of hippocampal cells was detected by tdt-mediated dutp nick end labeling assay. |
2019-07-26 |
2023-08-13 |
rat |
| Biao Cai, Shu Ye, Yan Wang, Ting-Ting Wang, Liang Wang, Ai-Juan Jiang, Zheng-Qing Fang, Guo-Ming Shen, Dao-Jun Xi. [Effects of Huangpu Tongqiao capsule on apoptosis of Alzheimer's disease cell model]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 43. issue 11. 2019-07-18. PMID:29945394. |
after primary cultured hippocampal neurons ad cell model was induced by aβ₂₅₋₃₅, cell survival rate was detected by mtt, cell apoptosis rate was assayed by flow cytometry, and protein expressions of bax, cyt c and caspase-3 were determined by western blot analysis. |
2019-07-18 |
2023-08-13 |
Not clear |
| Cleciane Waldetário Martins, Lívia Carla de Melo Rodrigues, Michael A Nitsche, Ester Miyuki Nakamura-Palacio. AMPA receptors are involved in prefrontal direct current stimulation effects on long-term working memory and GAP-43 expression. Behavioural brain research. vol 362. 2019-07-11. PMID:30654123. |
the prefrontal cortex (pfc) and hippocampus (hpc) were removed 24-h later and gap-43 (growth-associated protein) expression was measured by western blot analysis. |
2019-07-11 |
2023-08-13 |
rat |
| Rong-Rong Zhang, Ze-Xin Lin, Xin-Yi Lu, Xue Xia, Ren-Wang Jiang, Qu-Bo Che. CGY-1, a biflavonoid isolated from cardiocrinum giganteum seeds, improves memory deficits by modulating the cholinergic system in scopolamine-treated mice. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 111. 2019-06-17. PMID:30594789. |
furthermore, qpcr and western blot results revealed that the expressions of neurotrophic factors, brain-derived neurotrophic factor and nerve growth factor were upregulated in the hippocampus after cgy-1 treatment. |
2019-06-17 |
2023-08-13 |
mouse |
| M Göl, Ş Demiryürek, D S Kaplan, A Saracaloğlu, M Örkmez, A T Demiryüre. N-(p-amylcinnamoyl) anthranilic acid attenuates remedial effects of memantine on memory deficits following intracerebroventricular streptozotocin administration in rats. Archives italiennes de biologie. vol 157. issue 1. 2019-06-06. PMID:31111954. |
western blot analysis of hippocampal tissues revealed trpm2-l channel protein expression levels. |
2019-06-06 |
2023-08-13 |
rat |
| M Göl, Ş Demiryürek, D S Kaplan, A Saracaloğlu, M Örkmez, A T Demiryüre. N-(p-amylcinnamoyl) anthranilic acid attenuates remedial effects of memantine on memory deficits following intracerebroventricular streptozotocin administration in rats. Archives italiennes de biologie. vol 157. issue 1. 2019-06-06. PMID:31111954. |
western blot analysis in hippocampal tissues showed that trpm2-l protein expression was markedly suppressed in icv-stz administered group. |
2019-06-06 |
2023-08-13 |
rat |
| Cun-Quan Xiong, Hong-Cheng Zhou, Jian Wu, Nai-Zhou Gu. The Protective Effects and the Involved Mechanisms of Tanshinone IIA on Sepsis-Induced Brain Damage in Mice. Inflammation. vol 42. issue 1. 2019-06-03. PMID:30255286. |
western blot method was used to detect the expression levels of psd-95, syp, and iba-1 in the hippocampus tissue. |
2019-06-03 |
2023-08-13 |
mouse |
| Sally A Abuelezz, Nevien Hendaw. Insights into the potential antidepressant mechanisms of cilostazol in chronically restraint rats: impact on the Nrf2 pathway. Behavioural pharmacology. vol 29. issue 1. 2019-05-28. PMID:28763303. |
western blot and pcr showed that cilostazol favorably modulated the nrf2 protein and heme oxygenase-1 and nad(p)h: quinone oxidoreductase-1 gene expression in the hippocampus of crs rats. |
2019-05-28 |
2023-08-13 |
rat |
| Zhenzhen Qu, Lijing Jia, Tao Xie, Junli Zhen, Peipei Si, Zhiqiang Cui, Yan Xue, Can Sun, Weiping Wan. (-)-Epigallocatechin-3-Gallate Protects Against Lithium-Pilocarpine-Induced Epilepsy by Inhibiting the Toll-Like Receptor 4 (TLR4)/Nuclear Factor-κB (NF-κB) Signaling Pathway. Medical science monitor : international medical journal of experimental and clinical research. vol 25. 2019-05-22. PMID:30843525. |
the morris water maze test and hippocampal late-phase long-term potentiation (l-ltp) recordings were used to evaluate cognitive impairment, and tlr4, nf-kappab, and il-1ß levels were determined using western blot analysis. |
2019-05-22 |
2023-08-13 |
rat |
| Ahsia M Clayton, Qingmei Shao, Nina D Paauw, Ashtin B Giambrone, Joey P Granger, Junie P Warringto. Postpartum increases in cerebral edema and inflammation in response to placental ischemia during pregnancy. Brain, behavior, and immunity. vol 70. 2019-05-21. PMID:29588233. |
western blot analysis showed no changes in astrocyte marker, glial fibrillary acidic protein (gfap); however, the microglia marker, ionized calcium binding adaptor molecule (iba1) tended to increase in hippocampus of rupp-exposed rats. |
2019-05-21 |
2023-08-13 |
rat |
| Panchanan Maiti, Leela Paladugu, Gary L Dunba. Solid lipid curcumin particles provide greater anti-amyloid, anti-inflammatory and neuroprotective effects than curcumin in the 5xFAD mouse model of Alzheimer's disease. BMC neuroscience. vol 19. issue 1. 2019-05-16. PMID:29471781. |
levels of aβ aggregation, including oligomers and fibril formation, were assessed by dot blot assay, while aβ plaque load and neuronal morphology in the pre-frontal cortex (pfc) and hippocampus were assayed by immunolabeling with aβ-specific antibody and cresyl violet staining, respectively. |
2019-05-16 |
2023-08-13 |
mouse |
| Jing Gan, Qianyun Cai, Yi Qu, Fengyan Zhao, Chaomin Wan, Rong Luo, Dezhi M. miR-96 attenuates status epilepticus-induced brain injury by directly targeting Atg7 and Atg16L1. Scientific reports. vol 7. issue 1. 2019-05-09. PMID:28860495. |
in the present study, we employed immunofluorescence staining and western blot analysis to assess the expression of autophagy-related 7 (atg7) and atg16l1 and the status of autophagosome formation in the hippocampus of immature rats with se. |
2019-05-09 |
2023-08-13 |
rat |
| Hyo Young Jung, Hyun Jung Kwon, Woosuk Kim, Sung Min Nam, Jong Whi Kim, Kyu Ri Hahn, Dae Young Yoo, Moo-Ho Won, Yeo Sung Yoon, Dae Won Kim, In Koo Hwan. Phosphoglycerate Mutase 1 Promotes Cell Proliferation and Neuroblast Differentiation in the Dentate Gyrus by Facilitating the Phosphorylation of cAMP Response Element-Binding Protein. Neurochemical research. vol 44. issue 2. 2019-05-07. PMID:30460638. |
higher pgam1 protein expression was observed in the hippocampus of tat-pgam1-treated mice when compared with the hippocampi of control, tat peptide-, and control-pgam1-treated mice, using western blot analysis. |
2019-05-07 |
2023-08-13 |
mouse |
| Xiao-Peng Wang, Pin Ye, Jiao Lv, Lei Zhou, Zhong-Yi Qian, Yong-Jie Huang, Zhi-Hao Mu, Xie Wang, Xin-Jie Liu, Qi Wan, Zhi-Hong Yang, Fang Wang, Ying-Ying Zo. Expression Changes of NMDA and AMPA Receptor Subunits in the Hippocampus in rats with Diabetes Induced by Streptozotocin Coupled with Memory Impairment. Neurochemical research. vol 44. issue 4. 2019-04-26. PMID:30747310. |
by western blot analysis and immunofluorescence labeling, the hippocampus in diabetic rats showed a significant increase in protein expression nmdar subunits nr1, nr2a and nr2b and ampar subunit glur1. |
2019-04-26 |
2023-08-13 |
rat |
| Yvfeng Liang, Jiahong Li, Tao Jin, Ting Gu, Qingjie Zhu, Yizhong Hu, Yang Yang, Jisui Li, Donghong Wu, Kesheng Jiang, Xiaohong X. Bisphenol-A inhibits improvement of testosterone in anxiety- and depression-like behaviors in gonadectomied male mice. Hormones and behavior. vol 102. 2019-04-25. PMID:29778459. |
western blot analysis further showed that bpa reduced the levels of androgen receptor (ar) and gaba(a)α2 receptor of the hippocampus and the amygdala in sham and inhibited the rescue of tp in these proteins levels of gdx mice. |
2019-04-25 |
2023-08-13 |
mouse |
| Emily Moulton, Marisa Chamness, Dayan Kno. Characterizing changes in glucocorticoid receptor internalization in the fear circuit in an animal model of post traumatic stress disorder. PloS one. vol 13. issue 12. 2019-04-24. PMID:30532228. |
cy and nu grs within the medial prefrontal cortex (mpfc), dorsal hippocampus (dhipp), ventral hippocampus (vhipp), and amygdala (amy) were assayed using western blot. |
2019-04-24 |
2023-08-13 |
Not clear |
| Renato W de Oliveira, Guilherme S Julian, Juliana C Perry, Sergio Tufik, Jair R Chaga. Chronic intermittent hypoxia induces changes on the expression and activity of neprilysin (EC 3.4.24.11) in the brain of rats. Neuroscience letters. vol 678. 2019-04-15. PMID:29702204. |
western blot, qrt-pcr and enzyme activity assay, demonstrated that a six-week intermittent hypoxia increased nep expression and activity, selectively in temporal cortex, but not in the hippocampus and frontal cortex. |
2019-04-15 |
2023-08-13 |
rat |
| Sami Alzarea, Shafiqur Rahma. Effects of alpha-7 nicotinic allosteric modulator PNU 120596 on depressive-like behavior after lipopolysaccharide administration in mice. Progress in neuro-psychopharmacology & biological psychiatry. vol 86. 2019-04-15. PMID:29800595. |
we also examined the effects of pnu 120596 on iba-1 expression by using western blot analysis and immunofluorescence staining in the hippocampus and prefrontal cortex, the brain regions implicated in major depressive disorder. |
2019-04-15 |
2023-08-13 |
mouse |
| Rohan Sharma, Ravinder Gulia, Samarjit Bhattacharyy. Analysis of ubiquitination and ligand-dependent trafficking of group I mGluRs. Methods in cell biology. vol 149. 2019-04-08. PMID:30616814. |
we have illustrated the protocols of (i) maintenance and transient transfection in hek293t cells and primary hippocampal neurons, (ii) immunoprecipitation and western blot analysis to identify the ubiquitination of group i mglurs, (iii) endocytosis and recycling assay and (iv) image acquisition and analysis. |
2019-04-08 |
2023-08-13 |
Not clear |
| Shaokang Dang, Yong Lu, Qian Su, Tianwei Lin, Xiaoxiao Zhang, Huiping Zhang, Junli Zhang, Lin Zhang, Zhongliang Zhu, Hui L. H3K9 Acetylation of Tph2 Involved in Depression-like Behavior in Male, but not Female, Juvenile Offspring Rat Induced by Prenatal Stress. Neuroscience. vol 381. 2019-04-05. PMID:29625215. |
the mrna and protein expression levels of tph2 in the dorsal raphenucleus (drn), hippocampus, and prefrontal cortex were detected with quantitative real-time pcr and western blot analysis, respectively. |
2019-04-05 |
2023-08-13 |
rat |