| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Shailendra Kumar Maurya, Juhi Mishra, Sabiya Abbas, Sanghamitra Bandyopadhya. Correction to: Cypermethrin Stimulates GSK3β-Dependent Aβ and p-tau Proteins and Cognitive Loss in Young Rats: Reduced HB-EGF Signaling and Downstream Neuroinflammation as Critical Regulators. Molecular neurobiology. vol 56. issue 11. 2020-01-08. PMID:31471876. |
the authors noticed that fig. 1c (cortex), 1d (hippocampus), 4a (cortex), 4b (cortex) and the beta actin western blot of supplement 2a in the original article had errors. |
2020-01-08 |
2023-08-13 |
rat |
| Hui Wang, JiuLing Deng, Liang Chen, Ke Ding, Yi Wan. Acute glucose fluctuation induces inflammation and neurons apoptosis in hippocampal tissues of diabetic rats. Journal of cellular biochemistry. 2020-01-08. PMID:31713299. |
hippocampus bcl-2, bax, pten, fas, and myc were quantified by qrt-pcr and western blot analysis and mirror water maze (mwm) test was performed. |
2020-01-08 |
2023-08-13 |
rat |
| Hareram Birla, Chetan Keswani, Sachchida Nand Rai, Saumitra Sen Singh, Walia Zahra, Hagera Dilnashin, Aaina Singh Rathore, Surya Pratap Sing. Neuroprotective effects of Withania somnifera in BPA induced-cognitive dysfunction and oxidative stress in mice. Behavioral and brain functions : BBF. vol 15. issue 1. 2020-01-07. PMID:31064381. |
whereas, for the estimation of recovery of nmda receptor which is related to learning and memory in hippocampus region by western blot and immunohistochemistry. |
2020-01-07 |
2023-08-13 |
mouse |
| Bojana Rankov Petrovic, Dragan Hrncic, Dusan Mladenovic, Tatjana Simic, Sonja Suvakov, Djurdja Jovanovic, Nela Puskas, Ivan Zaletel, Milica Velimirovic, Valentina Cirkovic, Djuro Macut, Olivera Stanojlovic, Aleksandra Rasic-Markovi. Prenatal Androgenization Induces Anxiety-Like Behavior in Female Rats, Associated with Reduction of Inhibitory Interneurons and Increased BDNF in Hippocampus and Cortex. BioMed research international. vol 2019. 2020-01-03. PMID:31281833. |
the level of bdnf expression in the hippocampus and cerebral cortex was analyzed with the western blot test. |
2020-01-03 |
2023-08-13 |
rat |
| Ning Jiang, Jing-Wei Lv, Hai-Xia Wang, Qiong Wang, Cong Lu, Yu-Jie Yang, Hong Huang, Tian-Ji Xia, Guang-Hua Lv, Xin-Min Li. Antidepressant-like effects of 20(S)-protopanaxadiol in a mouse model of chronic social defeat stress and the related mechanisms. Phytotherapy research : PTR. vol 33. issue 10. 2019-12-26. PMID:31353678. |
additionally, western blot analysis revealed that csds exposure significantly downregulated bdnf, p-trkb/trkb, p-akt/akt, and p-mtor/mtor protein expression in the hippocampus. |
2019-12-26 |
2023-08-13 |
mouse |
| Maoxing Li, Yuting Zhu, Jing Li, Liping Chen, Wendi Tao, Xiaoling Li, Yan Qi. Effect and mechanism of verbascoside on hypoxic memory injury in plateau. Phytotherapy research : PTR. vol 33. issue 10. 2019-12-26. PMID:31364205. |
the protein expression of p-mtor, p-p70s6k, p-4e-bp1, and cleaved caspase-3 in the hippocampus tissue was determined by western blot. |
2019-12-26 |
2023-08-13 |
rat |
| Chun-Lei Ma, Hui Sun, Liu Yang, Xing-Tao Wang, Su Gao, Xiao-Wen Chen, Zhi-Yuan Ma, Gui-Hua Wang, Zhen Shi, Qing-Yin Zhen. Acid-Sensing Ion Channel 1a Modulates NMDA Receptor Function Through Targeting NR1/NR2A/NR2B Triheteromeric Receptors. Neuroscience. vol 406. 2019-12-24. PMID:30926548. |
using various experimental approaches including patch-clamp recordings on hippocampal slices and cho cells, primary cultures of hippocampal neurons, calcium imaging, western blot, cdna transfection studies, and transient middle cerebral artery occlusion (tmcao) mouse models, we demonstrate that stimulation of asic1a facilitates nmdar function and inhibition of asic1a suppresses nmdar over-activation. |
2019-12-24 |
2023-08-13 |
mouse |
| Meng-Meng Li, Ping Zhou, Xiao-Dong Chen, Huai-Sha Xu, Jun Wang, Ling Chen, Ning Zhang, Na Li. NO in the dPAG modulates panic-like responses and ASIC1a expression in the prefrontal cortex and hippocampus in mice. Biochemical and biophysical research communications. vol 511. issue 2. 2019-12-23. PMID:30770101. |
in our study, c57bl/6 mice received an intra-dpag injection of snap or 7-ni before ret; neurobehavioral tests were then conducted, followed by mechanistic evaluation through western blot analysis in the pfc and hippocampus. |
2019-12-23 |
2023-08-13 |
mouse |
| Ruicong Guan, Jing Lv, Fei Xiao, Youbing Tu, Yubo Xie, Li L. Potential role of the cAMP/PKA/CREB signalling pathway in hypoxic preconditioning and effect on propofol‑induced neurotoxicity in the hippocampus of neonatal rats. Molecular medicine reports. vol 20. issue 2. 2019-12-23. PMID:31257533. |
western blot and histological analyses demonstrated that hpc exerts multiple effects on the hippocampus, including the upregulation of camp and phosphorylation of creb. |
2019-12-23 |
2023-08-13 |
rat |
| Peng Wang, Bo-Ya Liu, Ming-Mei Wu, Xiao-Yan Wei, Sen Sheng, Si-Wei You, Li-Xin Shang, Fang Kuan. Moderate prenatal alcohol exposure suppresses the TLR4-mediated innate immune response in the hippocampus of young rats. Neuroscience letters. vol 699. 2019-12-17. PMID:30710662. |
the results showed that pae significantly up-regulated the expression of toll-interleukin-1 receptor (tir)-domain-containing adaptor protein inducing interferon (ifn)-β (trif), tnf-α, and il-1β in the rat hippocampus in the absence of lps, indicated by western blot assay. |
2019-12-17 |
2023-08-13 |
rat |
| Guomin Li, Lirong Zeng, Haiyan Cheng, Jingxian Han, Xuezhu Zhang, Hui Xi. Acupuncture Administration Improves Cognitive Functions and Alleviates Inflammation and Nuclear Damage by Regulating Phosphatidylinositol 3 Kinase (PI3K)/Phosphoinositol-Dependent Kinase 1 (PDK1)/Novel Protein Kinase C (nPKC)/Rac 1 Signaling Pathway in Senescence-Accelerated Prone 8 (SAM-P8) Mice. Medical science monitor : international medical journal of experimental and clinical research. vol 25. 2019-12-09. PMID:31152645. |
western blot was used to detect pi3k, pdk1, npkc, and rac 1 expression in hippocampal tissues. |
2019-12-09 |
2023-08-13 |
mouse |
| Juncao Chen, Xiaoyun Gong, Li Huang, Pingyang Chen, Tao Wang, Wei Zhou, Kaiju Luo, Jing Wan. MiR-199a-5p regulates sirtuin1 and PI3K in the rat hippocampus with intrauterine growth restriction. Scientific reports. vol 8. issue 1. 2019-12-06. PMID:30217997. |
changes in pi3k, sirt1 and caspase-3 protein expressions levels in the hippocampus were confirmed by western blot analysis (all p < 0.05). |
2019-12-06 |
2023-08-13 |
rat |
| Mehtab Khan, Bart P F Rutten, Myeong Ok Ki. MST1 Regulates Neuronal Cell Death via JNK/Casp3 Signaling Pathway in HFD Mouse Brain and HT22 Cells. International journal of molecular sciences. vol 20. issue 10. 2019-12-03. PMID:31117242. |
our western blot and immunofluorescence results indicate that hfd and stress-induced hippocampal ht22 cells activate mst1/jnk/caspase-3 (casp-3) signaling, which regulates neuronal cell apoptosis and beta-amyloid-cleaving enzyme (bace1) expression and leads to impaired cognition. |
2019-12-03 |
2023-08-13 |
mouse |
| Gisela Barbany, Håkan Persso. Regulation of Neurotrophin mRNA Expression in the Rat Brain by Glucocorticoids. The European journal of neuroscience. vol 4. issue 5. 2019-11-20. PMID:12106347. |
northern blot analysis was used to examine the effects of glucocorticoids on neurotrophin mrna expression in the rat cerebral cortex and hippocampus. |
2019-11-20 |
2023-08-12 |
rat |
| Shi-Hua Lin, Zhao Zhong Chong, Kenneth Maies. Nicotinamide: A Nutritional Supplement that Provides Protection Against Neuronal and Vascular Injury. Journal of medicinal food. vol 4. issue 1. 2019-11-20. PMID:12639285. |
in primary rat hippocampal neurons and rat cerebrovascular endothelial cells (ecs), cellular injury was determined through trypan blue dye exclusion, externalization of membrane phosphatidylserine (ps) residues, and activation of the mitogen-activated protein kinase p38 through western blot analysis. |
2019-11-20 |
2023-08-12 |
rat |
| Feng Jia, Ji-Yao Jiang, Yu-Min Liang, Qing Ma. The effect of hypothermia on the expression of TIMP-3 after traumatic brain injury in rats. Journal of neurotrauma. 2019-11-20. PMID:19413464. |
according to the rt-pcr and western blot analysis, the maximum mrna levels of timp-3 were reduced to 60.60%+/-2.30, 55.83%+/-1.80, 66.03%+/-2.10 and 64.51%+/-1.50 of the corresponding values in the normothermic group in injured and uninjured hemispheres (cortex and hippocampus) by hypothermia treatment, respectively (p < 0.01), while the respective maximum protein levels of timp-3 were reduced to 57.50%+/-1.50, 52.67%+/-2.20, 60.31%+/-2.50and 54.76%+/-1.40 (p < 0.01). |
2019-11-20 |
2023-08-12 |
rat |
| Yoshifumi Iwamaru, Hiroshi Kitani, Hiroyuki Okada, Takato Takenouchi, Yoshihisa Shimizu, Morikazu Imamura, Kohtaro Miyazawa, Yuichi Murayama, Edward A Hoover, Takashi Yokoyam. Proximity of SCG10 and prion protein in membrane rafts. Journal of neurochemistry. vol 136. issue 6. 2019-11-20. PMID:26663033. |
immunofluorescence and western blot analyses showed reduced levels of scg10 in the hippocampus of prion-infected mice, suggesting a possible association between scg10 levels and the prion neuropathogenesis. |
2019-11-20 |
2023-08-13 |
mouse |
| Jun Shi, Qiong Cai, Jingxing Zhang, Xiaolie He, Yigang Liu, Rongrong Zhu, Lingjing Ji. AM1241 alleviates MPTP-induced Parkinson's disease and promotes the regeneration of DA neurons in PD mice. Oncotarget. vol 8. issue 40. 2019-11-20. PMID:28978077. |
in addition, western blot assay and immunostaining results suggested that am1241 significantly activated pi3k/akt/mek phosphorylation and increased the expression of parkin and pink1, both in the substantia nigra and hippocampus. |
2019-11-20 |
2023-08-13 |
mouse |
| Guangming Tang, Huiyun Yang, Jing Chen, Mengrao Shi, Lingqing Ge, Xuhua Ge, Guoji Zh. Metformin ameliorates sepsis-induced brain injury by inhibiting apoptosis, oxidative stress and neuroinflammation via the PI3K/Akt signaling pathway. Oncotarget. vol 8. issue 58. 2019-11-20. PMID:29228667. |
neuronal apoptosis in the cerebral cortex, striatum and hippocampus was examined using tunel assay and immunohistochemistry, and western blot was applied to measure the expression of p-akt. |
2019-11-20 |
2023-08-13 |
mouse |
| Kate Goasdoue, Kirat Kishore Chand, Stephanie Melita Miller, Kah Meng Lee, Paul Bernard Colditz, Julie Anne Wixey, Stella Tracey Bjorkma. Seizures Are Associated with Blood-Brain Barrier Disruption in a Piglet Model of Neonatal Hypoxic-Ischaemic Encephalopathy. Developmental neuroscience. 2019-11-20. PMID:31048585. |
bbb disruption was evaluated in the parietal cortex and hippocampus by means of immunohistochemistry and western blot. |
2019-11-20 |
2023-08-13 |
Not clear |