| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Min Soo Kang, Woosuk Kim, Tae Hyeong Kim, Hyo Young Jung, Hyun Jung Kwon, Dae Won Kim, In Koo Hwang, Jung Hoon Cho. Changes of fat-mass and obesity-associated protein expression in the hippocampus in animal models of high-fat diet-induced obesity and D-galactose-induced aging. Laboratory animal research. vol 36. 2020-09-28. PMID:32647628. |
fto mrna and protein levels based on quantitative real-time polymerase chain reaction and western blot assays were slightly increased in the hippocampus of high-fat diet-fed mice compared to that in control mice. |
2020-09-28 |
2023-08-13 |
mouse |
| Cheng-Bo-Wen Zhao, Jie Liu, Jin-Li Shi, Shao-Nan Wang, Yong-Sheng Ding, Shuai He, Ming-Xuan Lin, Jing Luo, Yi-Nan Jiang, Li-Hua Bian, Zi-Wei Yao, Qiu-Yu Li, Xiao-Mei Wang, Jian-You Gu. Anxiolytic Effect of Alcohol-Water Extracted Suanzaoren-Wuweizi Herb-Pair by Regulating ECS-BDNF-ERK Signaling Pathway Expression in Acute Restraint Stress Male Rats. Evidence-based complementary and alternative medicine : eCAM. vol 2020. 2020-09-28. PMID:32655658. |
the concentration of bndf, erk1/2, p-erk1/2, camp-response element binding protein (creb), and p-creb expression in the prefrontal cortex and hippocampus of the rats was then measured by western blot. |
2020-09-28 |
2023-08-13 |
rat |
| Sang-Seo Park, Hye-Sang Park, Tae-Woon Kim, Sam-Jun Le. Effects of swimming exercise on social isolation-induced memory impairment and apoptosis in old rats. Journal of exercise rehabilitation. vol 16. issue 3. 2020-09-28. PMID:32724780. |
western blot analysis for bax, bcl-2, and cytochrome c in the hippocampus was conducted. |
2020-09-28 |
2023-08-13 |
rat |
| Lei Huang, Hai-Bin Fang, Hui-Hui Cheng, Sheng-Lan Mei, Yun-Ping Cheng, Yao Lv, Qing-Tao Meng, Zhong-Yuan Xi. Epigenetic modulation of the MAPK pathway prevents isoflurane-induced neuronal apoptosis and cognitive decline in aged rats. Experimental and therapeutic medicine. vol 20. issue 5. 2020-09-28. PMID:32952626. |
the hippocampus of each animal was harvested for quantitative pcr, tunel staining and western blot analysis. |
2020-09-28 |
2023-08-13 |
rat |
| Liu-Lin Xiong, Lu-Lu Xue, Ya Jiang, Zheng Ma, Yuan Jin, You-Cui Wang, Yang-Yang Wang, Qing-Jie Xia, Ying Zhang, Qiao Hu, Jia Liu, Ting-Hua Wan. Suppression of PDGF induces neuronal apoptosis after neonatal cerebral hypoxia and ischemia by inhibiting P-PI3K and P-AKT signaling pathways. Brain research. vol 1719. 2020-09-25. PMID:31082354. |
then, immunohistochemistry, immunofluorescence double staining of neun/pdgf, and western blot were used to validate the expression level of pdgf in the cortex and hippocampus at 6 hours (h), 12 h and 24 h after hi. |
2020-09-25 |
2023-08-13 |
rat |
| Emilia Metryka, Izabela Gutowska, Patrycja Kupnicka, Maciej Tarnowski, Marta Tkacz, Joanna Listos, Sylwia Talarek, Katarzyna Barczak, Dariusz Chlubek, Irena Baranowska-Bosiack. The expression of purinergic P2X4 and P2X7 receptors in selected mesolimbic structures during morphine withdrawal in rats. Brain research. vol 1719. 2020-09-25. PMID:31121160. |
in the present study the mrna and protein expression of purinergic p2x4 and p2x7 receptors in selected mesolimbic structures (striatum, hippocampus and prefrontal cortex) during morphine withdrawal in rats was investigated by rt-pcr and western blot analysis. |
2020-09-25 |
2023-08-13 |
rat |
| Si-Yu Lin, Jun Ma, Jian-Xiong An, Xiao-Yan Qian, Yong Wang, Doris K Cope, John P William. Ozone Inhibits APP/Aβ Production and Improves Cognition in an APP/PS1 Transgenic Mouse Model. Neuroscience. vol 418. 2020-09-24. PMID:31349006. |
prefrontal cortex and hippocampus amyloid-β precursor protein (app), along with other relevant biomarkers for ad, were measured through elisa, western blot and immunohistochemistry. |
2020-09-24 |
2023-08-13 |
mouse |
| Li-Mei Zhang, Li-Li Jia, Wen-Li Y. [Serum exosomes of rats with hepatic ischemia-reperfusion injury induce the damage of hippocampus and cerebral cortex]. Sheng li xue bao : [Acta physiologica Sinica]. vol 72. issue 4. 2020-09-24. PMID:32820307. |
the morphology and size of exosomes were observed by transmission electron microscope, the expression of exosomes markers cd63 and cd9 was detected by western blot, and the damage of liver and brain, levels of apoptosis and oxidative stress response in hippocampus and cerebral cortex were observed by serological and histological indexes. |
2020-09-24 |
2023-08-13 |
rat |
| Xue-Peng Bian, Rui-Fang Ji, Bei-Bei Liu, Jing-Yun Hu, Ming-Ming Li, Xiang-Li Xue, Shu-Jie Lo. [Aerobic exercise reduces the expression of pyroptosis-related proteins and inflammatory factors in hippocampus of mice with insulin resistance]. Sheng li xue bao : [Acta physiologica Sinica]. vol 72. issue 4. 2020-09-24. PMID:32820308. |
after the intervention, the expression of pyroptosis- and inflammation-related proteins in hippocampus was detected by western blot. |
2020-09-24 |
2023-08-13 |
mouse |
| América Vanoye-Carlo, Gisela Gómez-Lir. Differential expression of SV2A in hippocampal glutamatergic and GABAergic terminals during postnatal development. Brain research. vol 1715. 2020-09-18. PMID:30905653. |
total sv2a expression was assessed by real time pcr and western blot, while immunofluorescence was used to identify sv2a protein in the different hippocampal layers and its co-localization with gaba or glutamate vesicular transporters. |
2020-09-18 |
2023-08-13 |
rat |
| Guo-Quan Wang, Peng Zhou, Dao-Jun Xie, Shu Ye, Hua-Wu Gao, Yan Wang, Zheng-Qing Fang, Biao Ca. [Effects of Huangpu Tongqiao Capsules on EGFR-PLCγ signal pathway of hippocampus in rats with Alzheimer's disease]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 45. issue 9. 2020-09-17. PMID:32495567. |
western blot results showed that the protein expression levels of egfr, plcγ, ip3 r and p-tau in hippocampus of ad rats were significantly increased(p<0.01), and hptqc could reduce the protein expression of egfr, plcγ, ip3 r and p-tau in ad rats(p<0.05). |
2020-09-17 |
2023-08-13 |
rat |
| Xiangyong Feng, Wei Xiong, Mingqiong Yuan, Jian Zhan, Xiankun Zhu, Zhijie Wei, Xidong Chen, Xianbing Chen. Down-regulated microRNA-183 mediates the Jak/Stat signaling pathway to attenuate hippocampal neuron injury in epilepsy rats by targeting Foxp1. Cell cycle (Georgetown, Tex.). vol 18. issue 22. 2020-09-16. PMID:31571517. |
expression of mir-183, foxp1, jak1, stat1, and stat3 in rats' hippocampal tissues was determined by reverse transcription quantitative polymerase chain reaction (rt-qpcr) and western blot analysis. |
2020-09-16 |
2023-08-13 |
rat |
| Youbo Zuo, Xingping Hu, Qiuyan Yang, Lei Zhao, Xueli Chen, Jiangtao Lin, Tiande Yan. Preoperative vitamin-rich carbohydrate loading alleviates postoperative cognitive dysfunction in aged rats. Behavioural brain research. vol 373. 2020-09-14. PMID:31340174. |
the levels of endoplasmic reticulum (er) stress markers and apoptosis related proteins in the hippocampus were examined by western blot analysis. |
2020-09-14 |
2023-08-13 |
rat |
| Xin Liang, Jing Tang, Feng-Lei Chao, Yang Zhang, Lin-Mu Chen, Fei-Fei Wang, Chuan-Xue Tan, Yan-Min Luo, Qian Xiao, Lei Zhang, Ying-Qiang Qi, Lin Jiang, Chun-Xia Huang, Yuan Gao, Yong Tan. Exercise improves depressive symptoms by increasing the number of excitatory synapses in the hippocampus of CUS-Induced depression model rats. Behavioural brain research. vol 374. 2020-09-10. PMID:31369775. |
in this study, a sucrose preference test (spt) was used to evaluate the depression-like symptoms in the rats, and western blot, immunohistochemical and stereological analyses were performed to study the expression of synaptic-related proteins in the hippocampus and the changes in excitatory synapses in each sub-region. |
2020-09-10 |
2023-08-13 |
rat |
| Emilce Artur de la Villarmois, Mariela Fernanda Pére. Cognitive interference as a possible therapeutic strategy to prevent expression of benzodiazepine withdrawal. The European journal of neuroscience. vol 50. issue 11. 2020-09-02. PMID:31299121. |
then, a secondary goal is to determine how latent inhibition could alter functional plasticity and neuronal nitric oxide synthase enzyme (nos-1) expression within the hippocampus, by using multi-unitary cell recordings and western blot, respectively. |
2020-09-02 |
2023-08-13 |
rat |
| Cheng-Jing Li, Jun-Jie Li, Yi Jiang, Ya-Wei Mu, De-Xin Lu, Zi-Yao Xiao, Han-Yang Jiang, Jing-Jing Zhao, Xian-Hua Che. Decreased cpg15 augments oxidative stress in sleep deprived mouse brain. Biochemical and biophysical research communications. vol 522. issue 3. 2020-08-31. PMID:31787230. |
immunofluorescent and western blot analysis revealed that the expression of cpg15 protein decreased in the hippocampus, ventral group of the dorsal thalamus (vent), and somatosensory area of cerebral cortex (ssp) after 24-72 h of rem-sd, and the oxidative stress in these brain regions was increased in parallel, as indicated by the ratio of glutathione (gsh) to its oxidative product (gssg). |
2020-08-31 |
2023-08-13 |
mouse |
| Ashleigh L Osborne, Nadia Solowij, Ilijana Babic, Jeremy S Lum, Kelly A Newell, Xu-Feng Huang, Katrina Weston-Gree. Effect of cannabidiol on endocannabinoid, glutamatergic and GABAergic signalling markers in male offspring of a maternal immune activation (poly I:C) model relevant to schizophrenia. Progress in neuro-psychopharmacology & biological psychiatry. vol 95. 2020-08-26. PMID:31202911. |
the prefrontal cortex (pfc) and hippocampus (hpc) were collected for post-mortem receptor binding and western blot analyses (n = 8 per group). |
2020-08-26 |
2023-08-13 |
rat |
| Farhad Shibani, Ali Sahamsizadeh, Iman Fatemi, Mohammad Allahtavakoli, Jalal Hasanshahi, Mohammadreza Rahmani, Mahdieh Azin, Mahsa Hassanipour, Nazanin Mozafari, Ayat Kaeid. Effect of oleuropein on morphine-induced hippocampus neurotoxicity and memory impairments in rats. Naunyn-Schmiedeberg's archives of pharmacology. vol 392. issue 11. 2020-08-20. PMID:31236657. |
in order to evaluate the cleaved caspase-3, bax, and bcl2 protein expression (as biochemical markers of apoptosis) in ca1 area of hippocampus tissue, the western blot test was used. |
2020-08-20 |
2023-08-13 |
rat |
| Min Liang, Haiquan Zhong, Jing Rong, Yingchun Li, Chunting Zhu, Li Zhou, Rong Zho. Postnatal Lipopolysaccharide Exposure Impairs Adult Neurogenesis and Causes Depression-like Behaviors Through Astrocytes Activation Triggering GABAA Receptor Downregulation. Neuroscience. vol 422. 2020-08-13. PMID:31682957. |
immunohistochemistry staining and western blot were employed to detect adult neurogenesis, gabaergic system, glia activation and bdnf-trkb pathway in the hippocampus. |
2020-08-13 |
2023-08-13 |
mouse |
| Weijie Xie, Ting Zhu, Xi Dong, Fengwei Nan, Xiangbao Meng, Ping Zhou, Guibo Sun, Xiaobo Su. HMGB1-triggered inflammation inhibition of notoginseng leaf triterpenes against cerebral ischemia and reperfusion injury via MAPK and NF-κB signaling pathways. Biomolecules. vol 9. issue 10. 2020-08-12. PMID:31547018. |
the immunofluorescence and western blot analysis showed pngl decreased hmgb1 expression, suppressed the hmgb1-triggered inflammation, and inhibited microglia activation (iba1) in hippocampus and cortex, thus dose-dependently downregulating inflammatory cytokines including vcam-1, mmp-9, mmp-2, and icam-1 concentrations in ischemic brains. |
2020-08-12 |
2023-08-13 |
rat |