| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xu-Sheng Yan, Zhan-Jun Yang, Jian-Xin Jia, Wei Song, Xin Fang, Zhi-Ping Cai, Dong-Sheng Huo, He Wan. Protective mechanism of testosterone on cognitive impairment in a rat model of Alzheimer's disease. Neural regeneration research. vol 14. issue 4. 2020-10-01. PMID:30632505. |
nissl staining, immunohistochemistry, western blot assay, and enzyme-linked immunosorbent assay results showed that the number of intact hippocampal pyramidal cells, the dendritic spine density in the hippocampal ca1 region, the immune response and expression level of postsynaptic density protein 95 in the hippocampus, and the activities of superoxide dismutase and glutathione peroxidase were increased with testosterone treatment. |
2020-10-01 |
2023-08-13 |
rat |
| Zhu-Jin Song, San-Juan Yang, Lan Han, Bin Wang, Guoqi Zh. Postnatal calpeptin treatment causes hippocampal neurodevelopmental defects in neonatal rats. Neural regeneration research. vol 14. issue 5. 2020-10-01. PMID:30688269. |
western blot assay was performed to analyze the protein levels of akt, erk, p-akt, p-erk1/2, erk1/2, scop, pten, mtor, p-mtor, creb and p-creb in the hippocampus. |
2020-10-01 |
2023-08-13 |
rat |
| Michael Zhang, Kennett D Radford, Mercedes Driscoll, Salsabila Purnomo, Jean Kim, Kwang H Cho. Effects of subanesthetic intravenous ketamine infusion on neuroplasticity-related proteins in the prefrontal cortex, amygdala, and hippocampus of Sprague-Dawley rats. IBRO reports. vol 6. 2020-10-01. PMID:30723838. |
two hours after the infusion, brain tissue from the medial prefrontal cortex (mpfc), hippocampus, and amygdala were collected for western blot analyses. |
2020-10-01 |
2023-08-13 |
rat |
| Ya Ling, Dan-Dan Wang, Yu-Xiao Sun, Dong-Jing Zhao, Hong N. Neuro-Behavioral Status and the Hippocampal Expression of Metabolic Associated Genes in Wild-Type Rat Following a Ketogenic Diet. Frontiers in neurology. vol 10. 2020-10-01. PMID:30804881. |
the hippocampal mossy fiber sprouting, the expression levels of zinc transporters (znts) and lipid metabolism related genes were detected by timm staining, rt-qpcr and western blot analysis, respectively, on p58. |
2020-10-01 |
2023-08-13 |
rat |
| Xiaoying Gao, Mian Guo, Dawei Meng, Feixiang Sun, Lianyue Guan, Ying Cui, Yan Zhao, Xichun Wang, Xin Gu, Jiahang Sun, Sihua Q. Silencing MicroRNA-134 Alleviates Hippocampal Damage and Occurrence of Spontaneous Seizures After Intraventricular Kainic Acid-Induced Status Epilepticus in Rats. Frontiers in cellular neuroscience. vol 13. 2020-10-01. PMID:31031600. |
western blot showed that a mir-134 antagonist suppressed lesion-induced endoplasmic reticulum (er) stress and apoptosis related expression of chop, bim and cytochrome c, while facilitated the expression of creb at 24 h post ka-induced lesion in the hippocampus. |
2020-10-01 |
2023-08-13 |
rat |
| Mingjun Xiang, Yuting Jiang, Zhiying Hu, Yang Yang, Xiaoxue Du, Benson Oa Botchway, Marong Fan. Serotonin receptors 2A and 1A modulate anxiety-like behavior in post-traumatic stress disordered mice. American journal of translational research. vol 11. issue 4. 2020-10-01. PMID:31105836. |
protein expression levels of 5-ht2a and 5-ht1a receptors, erk1 and erk2, perk1, perk2 and c-myc in mice hippocampus were evaluated by western blot analysis and immunofluorescence labeling. |
2020-10-01 |
2023-08-13 |
mouse |
| Lin-Hui Zou, Ya-Jun Shi, Hua He, Shi-Mei Jiang, Fang-Fang Huo, Xiao-Mu Wang, Fan Wu, Lei M. Effects of FGF2/FGFR1 Pathway on Expression of A1 Astrocytes After Infrasound Exposure. Frontiers in neuroscience. vol 13. 2020-10-01. PMID:31130839. |
accordingly, expression levels of c3 and iba-1, as markers of a1 astrocytes and microglial cells, respectively, were both up-regulated in rat hippocampus following infrasound exposure, as demonstrated by western blot. |
2020-10-01 |
2023-08-13 |
rat |
| Kandaswamy Selvakumar, Senthamilselvan Bavithra, Gunasekaran Krishnamoorthy, Jagadeesan Arunakara. Impact of quercetin on tight junctional proteins and BDNF signaling molecules in hippocampus of PCBs-exposed rats. Interdisciplinary toxicology. vol 11. issue 4. 2020-10-01. PMID:31762681. |
the hippocampus was dissected and processed for pcr and western blot; serum pcb was observed in pcb treated animals, simultaneously quercetin treated animals showed pcb metabolites. |
2020-10-01 |
2023-08-13 |
rat |
| Soraya Wilke Saliba, Tiziana Bonifacino, Tsvetan Serchov, Giambattista Bonanno, Antônio Carlos Pinheiro de Oliveira, Bernd L Fiebic. Neuroprotective Effect of AM404 Against NMDA-Induced Hippocampal Excitotoxicity. Frontiers in cellular neuroscience. vol 13. 2020-10-01. PMID:31920563. |
in this present study, we investigated the effects of am404 on the production of inflammatory mediators and neuronal cell death induced by nmda in organotypic hippocampal slices cultures (ohsc) using qpcr, western blot (wb), and immunohistochemistry. |
2020-10-01 |
2023-08-13 |
Not clear |
| Yanning Li, Ruipeng Shen, Gehua Wen, Runtao Ding, Ao Du, Jichuan Zhou, Zhibin Dong, Xinghua Ren, Hui Yao, Rui Zhao, Guohua Zhang, Yan Lu, Xu W. Effects of Ketamine on Levels of Inflammatory Cytokines IL-6, IL-1β, and TNF-α in the Hippocampus of Mice Following Acute or Chronic Administration. Frontiers in pharmacology. vol 8. 2020-09-30. PMID:28373844. |
therefore, we set out to establish acute and chronic ketamine administration models in c57bl/6 mice, to evaluate spatial recognition memory and emotional response, to analyze the changes in the levels of the inflammatory cytokines interleukin-6 (il-6), interleukin-1β (il-1β), and tumor necrosis factor-α (tnf-α) in the mouse hippocampus, employing behavioral tests, western blot, quantitative reverse transcriptase-polymerase chain reaction (qrt-pcr) and immunohistochemistry. |
2020-09-30 |
2023-08-13 |
mouse |
| Hui Zhao, Bingyu Liang, Linjie Yu, Yun X. Anti-depressant-like effects of Jieyu chufan capsules in a mouse model of unpredictable chronic mild stress. Experimental and therapeutic medicine. vol 14. issue 2. 2020-09-30. PMID:28810562. |
in addition, synaptic density in the hippocampus was evaluated and western blot and immunostaining were used to analyze hippocampal expression of postsynaptic density protein-95 (psd95), synaptophysin (syn), cyclic adenosine monophosphate response element binding protein (creb), brain-derived neurotrophic factor (bdnf), akt and glycogen synthase kinase (gsk)-3β as well as their phosphorylated (p) versions. |
2020-09-30 |
2023-08-13 |
mouse |
| Xin-Hua Yang, Su-Qi Song, Yun X. Resveratrol ameliorates chronic unpredictable mild stress-induced depression-like behavior: involvement of the HPA axis, inflammatory markers, BDNF, and Wnt/β-catenin pathway in rats. Neuropsychiatric disease and treatment. vol 13. 2020-09-30. PMID:29138567. |
hippocampal protein expression of brain-derived neurotrophic factor (bdnf) and the wnt/β-catenin pathway were analyzed by western blot. |
2020-09-30 |
2023-08-13 |
rat |
| Elvira C Arellanes-Licea, José Ávila-Mendoza, Elizabeth C Ramírez-Martínez, Eugenia Ramos, Nancy Uribe-González, Carlos Arámburo, Teresa Morales, Maricela Lun. Upregulation of GH, but not IGF1, in the hippocampus of the lactating dam after kainic acid injury. Endocrine connections. vol 7. issue 2. 2020-09-30. PMID:29321175. |
gh mrna expression in lactating rats increased further after ka administration in the hippocampus and in the hypothalamus, in parallel to gh protein concentration in the hippocampus of ka-treated lactating rats (43% vs lactating control), as detected by western blot and immunofluorescence. |
2020-09-30 |
2023-08-13 |
rat |
| Isabella M Fuentes, Angela N Pierce, Elizabeth R Di Silvestro, Molly O Maloney, Julie A Christianso. Differential Influence of Early Life and Adult Stress on Urogenital Sensitivity and Function in Male Mice. Frontiers in systems neuroscience. vol 11. 2020-09-30. PMID:29379420. |
following testing, prostate and bladder tissues were used for mast cell and western blot analysis and rt-pcr was performed on mrna from hypothalamus, amygdala, and hippocampus. |
2020-09-30 |
2023-08-13 |
mouse |
| Libor Uttl, Tomas Petrasek, Hilal Sengul, Marketa Svojanovska, Veronika Lobellova, Karel Vales, Dominika Radostova, Grygoriy Tsenov, Hana Kubova, Anna Mikulecka, Jan Svoboda, Ales Stuchli. Chronic MK-801 Application in Adolescence and Early Adulthood: A Spatial Working Memory Deficit in Adult Long-Evans Rats But No Changes in the Hippocampal NMDA Receptor Subunits. Frontiers in pharmacology. vol 9. 2020-09-30. PMID:29487522. |
the western blot method was used to determine changes in nmda receptor subunit levels in the hippocampus. |
2020-09-30 |
2023-08-13 |
rat |
| Tianwei Lin, Shaokang Dang, Qian Su, Huiping Zhang, Junli Zhang, Lin Zhang, Xiaoxiao Zhang, Yong Lu, Hui Li, Zhongliang Zh. The Impact and Mechanism of Methylated Metabotropic Glutamate Receptors 1 and 5 in the Hippocampus on Depression-Like Behavior in Prenatal Stress Offspring Rats. Journal of clinical medicine. vol 7. issue 6. 2020-09-30. PMID:29882864. |
the mrna and protein expression levels of mglur1 and mglur5 in the hippocampus of offspring were detected with quantitative real-time pcr and western blot analysis, respectively. |
2020-09-30 |
2023-08-13 |
rat |
| Yueying Liu, Jieru Chen, Meifang Jin, Zhenhong Li, Tian Tian, Lili Li, Hong N. Relationship between changes in mitochondrial function and hippocampal neuronal apoptosis after recurrent convulsion during developmental stage. Experimental and therapeutic medicine. vol 16. issue 1. 2020-09-30. PMID:29896232. |
dynamic changes of mitochondrial fusion and division-related genes, mitochondrial fusion protein 2 (mfn2) and dynamin-related protein 1 (drp1), in the hippocampus after recurrent convulsion were observed using reverse transcription-polymerase chain reaction (rt-pcr)and western blot analysis. |
2020-09-30 |
2023-08-13 |
rat |
| You-Yu Gu, Ping Huang, Quan Li, Yu-Ying Liu, George Liu, Yu-Hui Wang, Ming Yi, Li Yan, Xiao-Hong Wei, Lei Yang, Bai-He Hu, Xin-Rong Zhao, Xin Chang, Kai Sun, Chun-Shui Pan, Yuan-Chen Cui, Qing-Fang Chen, Chuan-She Wang, Jing-Yu Fan, Zhi-Zhong Ma, Jing-Yan Ha. YangXue QingNao Wan and Silibinin Capsules, the Two Chinese Medicines, Attenuate Cognitive Impairment in Aged LDLR (+/-) Golden Syrian Hamsters Involving Protection of Blood Brain Barrier. Frontiers in physiology. vol 9. 2020-09-30. PMID:29910744. |
finally, to assess the expression of claudin-5, jam-1, occludin and zo-1 in hippocampus, western blot was carried out. |
2020-09-30 |
2023-08-13 |
Not clear |
| Xiao Li, Rui-Zhen Liu, Qi Zeng, Zhi-Hua Huang, Jian-Dong Zhang, Zong-Liang Liu, Jing Zeng, Hai Xia. 3'-Daidzein sulfonate sodium protects against memory impairment and hippocampal damage caused by chronic cerebral hypoperfusion. Neural regeneration research. vol 13. issue 9. 2020-09-30. PMID:30127116. |
western blot analysis was performed to investigate the phosphorylation of pka, erk1/2 and creb in the hippocampal pka/erk1/2/creb signaling pathway. |
2020-09-30 |
2023-08-13 |
rat |
| Junqiang Feng, Lifang Feng, Guiru Zhan. Mitochondrial damage in hippocampal neurons of rats with epileptic protein expression of Fas and caspase-3. Experimental and therapeutic medicine. vol 16. issue 3. 2020-09-30. PMID:30210599. |
finally, qpcr and western blot analysis were used to detect mrna and protein expression of fatty acid synthetase (fas), fas ligand (fasl) and caspase-3 in rat hippocampal neurons. |
2020-09-30 |
2023-08-13 |
rat |