| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Junqiang Feng, Lifang Feng, Guiru Zhan. Mitochondrial damage in hippocampal neurons of rats with epileptic protein expression of Fas and caspase-3. Experimental and therapeutic medicine. vol 16. issue 3. 2020-09-30. PMID:30210599. |
the qpcr and western blot results showed that the mrna and protein expression levels of fas, fasl and caspase-3 were significantly increased in the hippocampus of rat model group (p<0.01). |
2020-09-30 |
2023-08-13 |
rat |
| Chuan-Jie Wang, Yi Wu, Qun Zhang, Ke-Wei Yu, Yu-Yang Wan. An enriched environment promotes synaptic plasticity and cognitive recovery after permanent middle cerebral artery occlusion in mice. Neural regeneration research. vol 14. issue 3. 2020-09-30. PMID:30539814. |
the expression levels of growth-associated protein 43, synaptophysin and postsynaptic density protein 95 in the hippocampus were analyzed by western blot assay. |
2020-09-30 |
2023-08-13 |
mouse |
| Yan Hu, Tie-Cheng Guo, Xiang-Yu Zhang, Jun Tian, Yin-Shan L. Paired associative stimulation improves synaptic plasticity and functional outcomes after cerebral ischemia. Neural regeneration research. vol 14. issue 11. 2020-09-30. PMID:31290455. |
we measured mrna and protein expression levels of brain-derived neurotrophic factor and n-methyl-d-aspartate receptor 1 in the hippocampus using a real-time polymerase chain reaction and western blot assay. |
2020-09-30 |
2023-08-13 |
rat |
| Ying Du, Xiang-Dan Gong, Xin Fang, Fang Xing, Tian-Jiao Xia, Xiao-Ping G. Sevoflurane plays a reduced role in cognitive impairment compared with isoflurane: limited effect on fear memory retention. Neural regeneration research. vol 15. issue 1. 2020-09-30. PMID:31535657. |
western blot assay was performed to detect expression levels of d1 dopamine receptor, catechol-o-methyltransferase, phospho-glycogen synthase kinase-3β, and total glycogen synthase kinase-3β in the hippocampus. |
2020-09-30 |
2023-08-13 |
mouse |
| Xue Li, Lu Wang, Shuling Zhang, Xiang Hu, Huijun Yang, Lei X. Timing-Dependent Protection of Swimming Exercise against d-Galactose-Induced Aging-Like Impairments in Spatial Learning/Memory in Rats. Brain sciences. vol 9. issue 9. 2020-09-30. PMID:31540073. |
the number and density of synaptophysin (syp) and metabotropic glutamate receptor 1 (mglur1) in hippocampal dentate gyrus area, creb mrna and protein expression and dna methylation levels were determined respectively with immunohistochemistry, western blot, real-time pcr, and massarray methylation detection platform. |
2020-09-30 |
2023-08-13 |
rat |
| Ning-Wei Zhu, Xiao-Lan Yin, Ren Lin, Xiao-Lan Fan, Shi-Jie Chen, Yuan-Ming Zhu, Xiao-Zhen Zha. Possible mechanisms of lycopene amelioration of learning and memory impairment in rats with vascular dementia. Neural regeneration research. vol 15. issue 2. 2020-09-30. PMID:31552907. |
the distribution and expression of oxidative stress related protein, neuron-restrictive silencer factor, in hippocampal neurons were detected by immunofluorescence histochemistry and western blot assays. |
2020-09-30 |
2023-08-13 |
rat |
| Haiying Dong, Weiliang Cong, Xiwen Guo, Yuhua Wang, Shengju Tong, Qiang Li, Chengchong L. β-asarone relieves chronic unpredictable mild stress induced depression by regulating the extracellular signal-regulated kinase signaling pathway. Experimental and therapeutic medicine. vol 18. issue 5. 2020-09-30. PMID:31616508. |
in addition, the apoptosis of hippocampal neuronal cells was determined by flow cytometry, gene expression levels were detected by reverse transcription-quantitative polymerase chain reaction and protein levels were determined by western blot assay. |
2020-09-30 |
2023-08-13 |
rat |
| Hwayoung Lee, Minyoung Lee, Hyung-Ki Kim, Young Ock Kim, Jun-Tack Kwon, Hak-Jae Ki. Influence of clozapine on neurodevelopmental protein expression and behavioral patterns in animal model of psychiatric disorder induced by low-level of lead. The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology. vol 23. issue 6. 2020-09-30. PMID:31680768. |
western blot and immunohistochemical analyses of the hippocampus revealed that several neurodevelopmental proteins were downregulated in lead-exposed rats. |
2020-09-30 |
2023-08-13 |
rat |
| Baohua Li, Bin Wang, Min Chen, Gongying Li, Maosheng Fang, Jinguo Zha. Expression and interaction of TNF-α and VEGF in chronic stress-induced depressive rats. Experimental and therapeutic medicine. vol 10. issue 3. 2020-09-29. PMID:26622406. |
the relative mrna expression levels of tnf-α and vegf in the hippocampus of the experimental group were lower than those in the control group, and western blot analysis revealed that the protein expression of vegf and tnf-α was reduced in the experimental group. |
2020-09-29 |
2023-08-13 |
rat |
| Zheng-Jian Liao, Ri-Sheng Liang, Song-Sheng Shi, Chun-Hua Wang, Wei-Zhong Yan. Effect of baicalin on hippocampal damage in kainic acid-induced epileptic mice. Experimental and therapeutic medicine. vol 12. issue 3. 2020-09-29. PMID:27588062. |
western blot analysis was used to detect the expression of bcl-2 and cleaved caspase-3 proteins in the hippocampus, while reverse transcription-quantitative polymerase chain reaction was used to quantify hippocampal mir-497 expression. |
2020-09-29 |
2023-08-13 |
mouse |
| Wensen Pan, Shuo Han, Lin Kang, Sha Li, Juan Du, Huixian Cu. Effects of dihydrotestosterone on synaptic plasticity of the hippocampus in mild cognitive impairment male SAMP8 mice. Experimental and therapeutic medicine. vol 12. issue 3. 2020-09-29. PMID:27588067. |
to determine the regulatory mechanisms of dht in the cognitive capacity, the effects of dht on the morphology of the synapse and the expression of synaptic marker proteins in the hippocampus were investigated using immunohistochemistry, qpcr and western blot analysis. |
2020-09-29 |
2023-08-13 |
mouse |
| Chunhong Song, Ling Xu. Roles of the µ-opioid receptor and its related signaling pathways in the pathogenesis of premenstrual syndrome liver-qi stagnation. Experimental and therapeutic medicine. vol 13. issue 6. 2020-09-29. PMID:28587388. |
the protein expression level of mor within rat hippocampal tissue was detected via western blot analysis and cyclic adenosine monophosphate (camp) levels within the supernatant of a rat hippocampal cell culture were determined by elisa. |
2020-09-29 |
2023-08-13 |
rat |
| Chunhong Song, Ling Xu. Roles of the µ-opioid receptor and its related signaling pathways in the pathogenesis of premenstrual syndrome liver-qi stagnation. Experimental and therapeutic medicine. vol 13. issue 6. 2020-09-29. PMID:28587388. |
the western blot analysis indicated that the hippocampal expression level of mor was significantly elevated in the pms liver-qi stagnation model group. |
2020-09-29 |
2023-08-13 |
rat |
| Yuqin Ye, Yongxiang Yang, Chen Chen, Ze Li, Yanfeng Jia, Xinhong Su, Chaoxian Wang, Xiaosheng H. Electroacupuncture Improved Hippocampal Neurogenesis following Traumatic Brain Injury in Mice through Inhibition of TLR4 Signaling Pathway. Stem cells international. vol 2017. 2020-09-29. PMID:28848607. |
the hippocampal level of tlr4 and downstream molecules and inflammatory cytokines were, respectively, detected by western blot and enzyme-linked immunosorbent assay. |
2020-09-29 |
2023-08-13 |
mouse |
| Richard Justin Garling, Lora Talley Watts, Shane Sprague, Murat Digicayliogl. Progesterone modulates mTOR in the hippocampus of mice after traumatic brain injury. Neural regeneration research. vol 13. issue 3. 2020-09-29. PMID:29623927. |
the hippocampus was then harvested 72 hours post injury and prepared for western blot analysis. |
2020-09-29 |
2023-08-13 |
mouse |
| Huili Jiang, Xuhui Zhang, Jun Lu, Hong Meng, Yang Sun, Xinjing Yang, Bingcong Zhao, Tuya Ba. Antidepressant-Like Effects of Acupuncture-Insights From DNA Methylation and Histone Modifications of Brain-Derived Neurotrophic Factor. Frontiers in psychiatry. vol 9. 2020-09-29. PMID:29636708. |
the expression of serum bdnf was detected by enzyme-linked immunosorbent assay (elisa), the hippocampal bdnf, acetylation levels in histone h3 lysine 9 (ach3k9), and hdac2 by western blot, the hippocampal mrna of bdnf by rt-polymerase chain reaction (pcr). |
2020-09-29 |
2023-08-13 |
rat |
| Kwon Young Lee, Dae Young Yoo, Hyo Young Jung, Loktam Baek, Hangyul Lee, Hyun Jung Kwon, Jin Young Chung, Seok Hoon Kang, Dae Won Kim, In Koo Hwang, Jung Hoon Cho. Decrease in glucose transporter 1 levels and translocation of glucose transporter 3 in the dentate gyrus of C57BL/6 mice and gerbils with aging. Laboratory animal research. vol 34. issue 2. 2020-09-29. PMID:29937912. |
western blot analysis showed that glut3 expression in the hippocampal homogenates was slightly, although not significantly, decreased with age in mice and gerbils, respectively. |
2020-09-29 |
2023-08-13 |
mouse |
| Adrienne M Grech, Udani Ratnayake, Anthony J Hannan, Maarten van den Buuse, Rachel A Hil. Sex-Dependent Effects of Environmental Enrichment on Spatial Memory and Brain-Derived Neurotrophic Factor (BDNF) Signaling in a Developmental "Two-Hit" Mouse Model Combining BDNF Haploinsufficiency and Chronic Glucocorticoid Stimulation. Frontiers in behavioral neuroscience. vol 12. 2020-09-29. PMID:30356704. |
at week 16 dorsal hippocampus tissue was obtained for western blot analysis of expression levels of bdnf, the bdnf receptor trkb, and nmda receptor subunits, glunr1, 2a and 2b. |
2020-09-29 |
2023-08-13 |
mouse |
| Sung Woo Park, Rodrigo B Mansur, Yena Lee, Jae-Hon Lee, Mi Kyoung Seo, Ah Jeong Choi, Roger S McIntyre, Jung Goo Le. Liraglutide Activates mTORC1 Signaling and AMPA Receptors in Rat Hippocampal Neurons Under Toxic Conditions. Frontiers in neuroscience. vol 12. 2020-09-29. PMID:30405339. |
western blot analyses were performed to assess changes in mtorc1-mediated proteins, brain-derived neurotrophic factor (bdnf), and various synaptic proteins (psd-95, synapsin i, and glua1) in rat hippocampal cultures under toxic conditions induced by dexamethasone, which causes hippocampal cell death. |
2020-09-29 |
2023-08-13 |
rat |
| Lili Zhong, Hong Liu, Weijia Zhang, Xu Liu, Bo Jiang, Hongxin Fei, Zhongren Su. Ellagic acid ameliorates learning and memory impairment in APP/PS1 transgenic mice via inhibition of β-amyloid production and tau hyperphosphorylation. Experimental and therapeutic medicine. vol 16. issue 6. 2020-09-29. PMID:30542451. |
expression levels of app, aβ, rac-αserine/threonine-protein kinase and glycogen synthase kinase (gsk)3β in the hippocampus were determined by western blot analysis and elisa. |
2020-09-29 |
2023-08-13 |
mouse |