| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Rosemarie E Perry, Millie Rincón-Cortés, Stephen H Braren, Annie N Brandes-Aitken, Maya Opendak, Gabriella Pollonini, Divija Chopra, C Cybele Raver, Cristina M Alberini, Clancy Blair, Regina M Sulliva. Corticosterone administration targeting a hypo-reactive HPA axis rescues a socially-avoidant phenotype in scarcity-adversity reared rats. Developmental cognitive neuroscience. vol 40. 2020-03-13. PMID:31704654. |
western blot analysis of brain tissue revealed that glucocorticoid receptor levels in the dorsal (but not ventral) hippocampus and medial prefrontal cortex were significantly elevated in scarcity-adversity reared rats following the social approach test. |
2020-03-13 |
2023-08-13 |
human |
| Mohammad Shabani, Fariba Ebrahimpoor, Maryam Arab Firouzjaei, Leila Kamali, Seyed Mostafa Shid Moosavi, Ali Noorafshan, Masoud Haghan. Modulation of sphingosine-1-phosphate receptor by FTY720 contributes in improvement of hepatic encephalopathy induced by bile duct ligation. Brain research bulletin. vol 146. 2020-03-10. PMID:30660717. |
the cellular and molecular mechanisms that led to hippocampal dysfunction in bile duct ligation (bdl)-induced he and neuroprotective mechanisms of fty720 administration were evaluated using whole-cell patch clamp, field-potential recording, western blot, stereology and behavioral experiments. |
2020-03-10 |
2023-08-13 |
Not clear |
| Linda Marschner, An Schreurs, Benoit Lechat, Jesper Mogensen, Anton Roebroek, Tariq Ahmed, Detlef Balschu. Single mild traumatic brain injury results in transiently impaired spatial long-term memory and altered search strategies. Behavioural brain research. vol 365. 2020-03-09. PMID:29499284. |
furthermore, western blot analysis showed a short-term increase in hippocampal gfap expression, most likely indicating astrogliosis, which is typically related to injuries of the central nervous system. |
2020-03-09 |
2023-08-13 |
Not clear |
| Jiabao Hou, Qianni Shen, Xing Wan, Bo Zhao, Yang Wu, Zhongyuan Xi. REM sleep deprivation-induced circadian clock gene abnormalities participate in hippocampal-dependent memory impairment by enhancing inflammation in rats undergoing sevoflurane inhalation. Behavioural brain research. vol 364. 2020-03-09. PMID:30779975. |
western blot analysis revealed that sleep deprivation inhibited hippocampal bmal1 and egr1 expression for more than 7 days after sevoflurane inhalation. |
2020-03-09 |
2023-08-13 |
rat |
| Jianguo Li, Jing Chen, Na Ma, Deping Yan, Ying Wang, Xin Zhao, Yu Zhang, Ce Zhan. Effects of corticosterone on the expression of mature brain-derived neurotrophic factor (mBDNF) and proBDNF in the hippocampal dentate gyrus. Behavioural brain research. vol 365. 2020-03-09. PMID:30851317. |
next, using western blot assay, we showed that cort exposure increased the probdnf level in the ventral hippocampal dentate gyrus (dg), decreased the mbdnf level in the dorsal and ventral dg, and decreased the mbdnf/probdnf ratio in the hippocampal dg. |
2020-03-09 |
2023-08-13 |
rat |
| Zhongwei Xiong, Kai Zhang, Tamaki Ishima, Qian Ren, Min Ma, Yaoyu Pu, Lijia Chang, Jincao Chen, Kenji Hashimot. Lack of rapid antidepressant effects of Kir4.1 channel inhibitors in a chronic social defeat stress model: Comparison with (R)-ketamine. Pharmacology, biochemistry, and behavior. vol 176. 2020-02-25. PMID:30502360. |
western blot analysis of kir4.1 protein in the brain regions (prefrontal cortex, nucleus accumbens, hippocampus) from csds susceptible mice and control mice (no csds) was performed. |
2020-02-25 |
2023-08-13 |
mouse |
| Daiyue Chang, Jinghua Zhao, Xintong Zhang, HuiMin Lian, XueMan Du, Rui Yuan, Yajing Wen, Li Ga. Effect of ketamine combined with DHA on lipopolysaccharide-induced depression-like behavior in rats. International immunopharmacology. vol 75. 2020-02-14. PMID:31377587. |
western blot results showed that ketamine combined with dha can effectively inhibit the expression of nf-kb in hippocampus and pc12 cells, and increase the expression of p-creb and bdnf. |
2020-02-14 |
2023-08-13 |
rat |
| Yunfeng Zhou, Xue Tao, Zhi Wang, Li Feng, Lisha Wang, Xinmin Liu, Ruile Pan, Yonghong Liao, Qi Chan. Hippocampus Metabolic Disturbance and Autophagy Deficiency in Olfactory Bulbectomized Rats and the Modulatory Effect of Fluoxetine. International journal of molecular sciences. vol 20. issue 17. 2020-02-14. PMID:31480539. |
subsequently, the hippocampus was harvested for metabonomics analysis and western blot detection. |
2020-02-14 |
2023-08-13 |
rat |
| Jingjing Li, Beibei Liu, Ming Cai, Xiaojing Lin, Shujie Lo. Glucose metabolic alterations in hippocampus of diabetes mellitus rats and the regulation of aerobic exercise. Behavioural brain research. vol 364. 2020-02-13. PMID:29113873. |
the glucose metabolites and key enzymes involved in glucose metabolism in hippocampus were respectively detected by gc/ms based metabolomics and western blot. |
2020-02-13 |
2023-08-13 |
rat |
| Jingjing Wang, Tianzhu Zhang, Xiaoxiao Liu, Huimei Fan, Chunyan We. Aqueous extracts of se-enriched Auricularia auricular attenuates D-galactose-induced cognitive deficits, oxidative stress and neuroinflammation via suppressing RAGE/MAPK/NF-κB pathway. Neuroscience letters. vol 704. 2020-02-05. PMID:30953738. |
further, hippocampal levels of rage, p-erk, p-jnk, p-p38 and p-nf-κb were detected by western blot and the rage expression was confirmed by immunohistochemistry. |
2020-02-05 |
2023-08-13 |
mouse |
| Hae Jin Lee, Sung-Kwon Lee, Dong-Ryung Lee, Bong-Keun Choi, Bao Le, Seung Hwan Yan. Ameliorating effect of Citrus aurantium extracts and nobiletin on β‑amyloid (1‑42)‑induced memory impairment in mice. Molecular medicine reports. vol 20. issue 4. 2020-02-04. PMID:31432129. |
acetylcholinesterase (ache) activity was investigated in the hippocampus and cortex using commercial kits and the analysis of bax, bcl‑2, and cleaved caspase‑3 protein expression by western blot assays was used to confirm the anti‑apoptotic mechanism of cae and nobiletin. |
2020-02-04 |
2023-08-13 |
mouse |
| Yong-Hyun Ko, Seung-Hwan Kwon, Seok-Yong Lee, Choon-Gon Jan. Isoorientin improves scopolamine-induced cognitive impairments by restoring the cholinergic system, antioxidant defense, and p-CREB/BDNF signaling in the hippocampus and frontal cortex. Archives of pharmacal research. vol 42. issue 8. 2020-02-03. PMID:31350730. |
moreover, western blot results indicated that iso reversed the decreases in expression of phosphorylated camp response element binding (creb) and brain-derived neurotrophic factor (bdnf) in the hippocampus and frontal cortex of scopolamine-treated mice. |
2020-02-03 |
2023-08-13 |
mouse |
| Panupong Hansrivijit, Suteera Vibulyaseck, Montree Maneepark, Anan Srikiatkhachorn, Saknan Bongsebandhu-Phubhakd. GluN2A/B ratio elevation induced by cortical spreading depression: electrophysiological and quantitative studies of the hippocampus. The journal of physiological sciences : JPS. vol 65. issue Suppl 2. 2020-01-27. PMID:31941175. |
western blot analysis of the hippocampus was performed to confirm the quantitative change of glun2a/b ratio. |
2020-01-27 |
2023-08-13 |
rat |
| Panupong Hansrivijit, Suteera Vibulyaseck, Montree Maneepark, Anan Srikiatkhachorn, Saknan Bongsebandhu-Phubhakd. GluN2A/B ratio elevation induced by cortical spreading depression: electrophysiological and quantitative studies of the hippocampus. The journal of physiological sciences : JPS. vol 65. issue Suppl 2. 2020-01-27. PMID:31941175. |
western blot analysis (n = 30) revealed an increase in glun2a subunits and a decrease in glun2b subunits in the hippocampus ipsilateral to the csd induction. |
2020-01-27 |
2023-08-13 |
rat |
| Haiyu Mu, Zhifei Wang, Xianjuan Zhang, Dongmeng Qian, Yuyang Wang, Shasha Jiang, Shuzhen Liang, Bin Wan. HCMV-encoded IE2 induces anxiety-depression and cognitive impairment in UL122 genetically-modified mice. International journal of clinical and experimental pathology. vol 12. issue 11. 2020-01-17. PMID:31933804. |
level of fibroblast growth factor 2 (fgf2) protein in the hippocampus cornu ammonia areas (ca1, ca3) and dentate gyrus (dg) of the experimental group was significantly lower, consistent with immunohistochemical staining and western blot for neuron-specific nuclear protein (neun) and glial fibrillary acidic protein (gfap). |
2020-01-17 |
2023-08-13 |
mouse |
| Cesar D Solís, Teresa Morale. Lactation diminishes lesion-induced permeability of tracers into the brain. Brain research bulletin. vol 144. 2020-01-16. PMID:30502400. |
western blot analysis of tight junction proteins showed a decrease of claudin-5 and occludin but not of zonula occludens-1 in the hippocampus of both virgin and lactating rats. |
2020-01-16 |
2023-08-13 |
rat |
| Yinian Zhang, Huateng Dong, Lei Duan, Guoqiang Yuan, Wentao Liang, Qiao Li, Xinding Zhang, Yawen Pa. SLC1A2 mediates refractory temporal lobe epilepsy with an initial precipitating injury by targeting the glutamatergic synapse pathway. IUBMB life. vol 71. issue 2. 2020-01-13. PMID:30360015. |
hippocampal expression of the proteins solute carrier family 1 member 2 (slc1a2), glial fibrillary acidic protein, interleukin-1β (il-1β), tumor necrosis factor α (tnf-α), and n-methyl-d-aspartic acid receptor (nmdar) was determined by elisa and western blot. |
2020-01-13 |
2023-08-13 |
rat |
| Xiaolong Zhang, Hongmin Bu, Yan Jiang, Guangda Sun, Ruizhi Jiang, Xiaoyan Huang, Huifang Duan, Zhiheng Huang, Qinan W. The antidepressant effects of apigenin are associated with the promotion of autophagy via the mTOR/AMPK/ULK1 pathway. Molecular medicine reports. vol 20. issue 3. 2020-01-13. PMID:31322238. |
to investigate the underlining mechanisms, the hippocampal levels of p62 and microtubule‑associated protein light chain 3‑ii/i (lc3‑ii/i) were measured using western blot analysis. |
2020-01-13 |
2023-08-13 |
mouse |
| Peng Yuan, Jian Zhang, Liang Li, Zhendi Son. Fluoxetine Attenuated Anxiety-Like Behaviors in Streptozotocin-Induced Diabetic Mice by Mitigating the Inflammation. Mediators of inflammation. vol 2019. 2020-01-13. PMID:31396018. |
after completing these behavioral tests, mice were sacrificed and western blot was used to detect the oligodendrocyte and astrocyte maker proteins in hippocampal tissues. |
2020-01-13 |
2023-08-13 |
mouse |
| Mahshid Hosseinzadeh, Hamid Gholami Pourbadie, Fariba Khodagholi, Mahtab Daftari, Nima Naderi, Fereshteh Motamed. Preconditioning with toll-like receptor agonists attenuates seizure activity and neuronal hyperexcitability in the pilocarpine rat model of epilepsy. Neuroscience. vol 408. 2020-01-09. PMID:31026566. |
24 h after seizure induction, the hippocampal level of pro/anti-inflammatory mediators and electrophysiological properties of the dentate gyrus (dg) granular cells were investigated by western blot and whole cell patch clamp techniques, respectively. |
2020-01-09 |
2023-08-13 |
rat |