| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Laura Baroncelli, Alessandro Sale, Alessandro Viegi, José Fernando Maya Vetencourt, Roberto De Pasquale, Sara Baldini, Lamberto Maffe. Experience-dependent reactivation of ocular dominance plasticity in the adult visual cortex. Experimental neurology. vol 226. issue 1. 2010-10-28. PMID:20713044. |
we also found that ee leads to a reduced intracortical gabaergic inhibition and an increased bdnf expression and that the modulation of these molecular factors is neutralized by cortical infusion of the 5-ht synthesis inhibitor pcpa. |
2010-10-28 |
2023-08-12 |
rat |
| Eleni Païzanis, Thibault Renoir, Vincent Lelievre, Françoise Saurini, Maxette Melfort, Cecilia Gabriel, Nicholas Barden, Elisabeth Mocaër, Michel Hamon, Laurence Lanfume. Behavioural and neuroplastic effects of the new-generation antidepressant agomelatine compared to fluoxetine in glucocorticoid receptor-impaired mice. The international journal of neuropsychopharmacology. vol 13. issue 6. 2010-09-29. PMID:19775499. |
glucocorticoid receptor-impaired (gr-i) mice, a transgenic model for affective disorders with hypothalamic-pituitary-adrenal (hpa) axis feedback control deficit, were used to assess the antidepressant-like effects of the mixed melatonin receptor agonist/5-ht(2c) receptor antagonist, agomelatine, compared to the selective 5-ht reuptake inhibitor (ssri), fluoxetine, on hippocampal neurogenesis, gr and bdnf expression and antidepressant-responsive behaviour (tail suspension test, tst). |
2010-09-29 |
2023-08-12 |
mouse |
| Chad E Beyer, Jason M Dwyer, Michael J Piesla, Brian J Platt, Ru Shen, Zia Rahman, Karen Chan, Melissa T Manners, Tarek A Samad, Jeffrey D Kennedy, Brendan Bingham, Garth T Whitesid. Depression-like phenotype following chronic CB1 receptor antagonism. Neurobiology of disease. vol 39. issue 2. 2010-09-10. PMID:20381618. |
additionally, chronic treatment with rimonabant produced decreases in frontal cortex serotonin levels, marked reductions in hippocampal cell proliferation, survival, and bdnf levels, and elevations in the concentrations of pro-inflammatory cytokines including interferon gamma and tnf alpha. |
2010-09-10 |
2023-08-12 |
rat |
| Susana Aznar, Anders B Klein, Martin A Santini, Gitte M Knudsen, Fritz Henn, Peter Gass, Barbara Vollmay. Aging and depression vulnerability interaction results in decreased serotonin innervation associated with reduced BDNF levels in hippocampus of rats bred for learned helplessness. Synapse (New York, N.Y.). vol 64. issue 7. 2010-09-08. PMID:20222154. |
aging and depression vulnerability interaction results in decreased serotonin innervation associated with reduced bdnf levels in hippocampus of rats bred for learned helplessness. |
2010-09-08 |
2023-08-12 |
rat |
| Susana Aznar, Anders B Klein, Martin A Santini, Gitte M Knudsen, Fritz Henn, Peter Gass, Barbara Vollmay. Aging and depression vulnerability interaction results in decreased serotonin innervation associated with reduced BDNF levels in hippocampus of rats bred for learned helplessness. Synapse (New York, N.Y.). vol 64. issue 7. 2010-09-08. PMID:20222154. |
both reduced hippocampal serotonin neurotransmission and brain-derived neurotrophic factor (bdnf) levels have been associated with increased depression vulnerability and are also regulated during aging. |
2010-09-08 |
2023-08-12 |
rat |
| Susana Aznar, Anders B Klein, Martin A Santini, Gitte M Knudsen, Fritz Henn, Peter Gass, Barbara Vollmay. Aging and depression vulnerability interaction results in decreased serotonin innervation associated with reduced BDNF levels in hippocampus of rats bred for learned helplessness. Synapse (New York, N.Y.). vol 64. issue 7. 2010-09-08. PMID:20222154. |
an exacerbated age-related loss of serotonin fiber density specific for the ca1 area was observed in the clh animals, whereas reduced hippocampal bdnf levels were seen in young and old clh when compared with age-matched cnlh controls. |
2010-09-08 |
2023-08-12 |
rat |
| Bárbara Aisa, Francisco J Gil-Bea, Maite Solas, Mónica García-Alloza, Christopher P Chen, Mitchell K Lai, Paul T Francis, María Javier Ramíre. Altered NCAM expression associated with the cholinergic system in Alzheimer's disease. Journal of Alzheimer's disease : JAD. vol 20. issue 2. 2010-09-07. PMID:20164549. |
we have studied, in postmortem brain tissue, the relationship between levels of synaptic markers (ncam and bdnf), neurochemical measurements (cholinacetyltransferase activity, serotonin, dopamine, gaba, and glutamate levels), and clinical data (cognitive status measured as mmse score). |
2010-09-07 |
2023-08-12 |
Not clear |
| Patrizia Bianchi, Elisabetta Ciani, Sandra Guidi, Stefania Trazzi, Daniela Felice, Gabriele Grossi, Mercedes Fernandez, Alessandro Giuliani, Laura Calzà, Renata Bartesagh. Early pharmacotherapy restores neurogenesis and cognitive performance in the Ts65Dn mouse model for Down syndrome. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 26. 2010-07-22. PMID:20592198. |
in the hippocampus of untreated p15 ts65dn mice, we found normal 5-ht levels but a lower expression of 5-ht1a receptors and brain-derived neurotrophic factor (bdnf). |
2010-07-22 |
2023-08-12 |
mouse |
| T L Baker-Herman, R W Bavis, J M Dahlberg, A Z Mitchell, J E R Wilkerson, F J Golder, P M Macfarlane, J J Watters, M Behan, G S Mitchel. Differential expression of respiratory long-term facilitation among inbred rat strains. Respiratory physiology & neurobiology. vol 170. issue 3. 2010-06-28. PMID:20036763. |
more complex relationships were found for 5-ht(7), bdnf and trkb mrna. |
2010-06-28 |
2023-08-12 |
rat |
| T L Baker-Herman, R W Bavis, J M Dahlberg, A Z Mitchell, J E R Wilkerson, F J Golder, P M Macfarlane, J J Watters, M Behan, G S Mitchel. Differential expression of respiratory long-term facilitation among inbred rat strains. Respiratory physiology & neurobiology. vol 170. issue 3. 2010-06-28. PMID:20036763. |
bn had higher 5-ht(7) and trkb mrna versus f344; bn and lewis had higher bdnf mrna levels versus f344. |
2010-06-28 |
2023-08-12 |
rat |
| Antonio Terracciano, Toshiko Tanaka, Angelina R Sutin, Barbara Deiana, Lenuta Balaci, Serena Sanna, Nazario Olla, Andrea Maschio, Manuela Uda, Luigi Ferrucci, David Schlessinger, Paul T Cost. BDNF Val66Met is associated with introversion and interacts with 5-HTTLPR to influence neuroticism. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 35. issue 5. 2010-06-21. PMID:20042999. |
finally, on the basis of recent reports of an epistatic effect between bdnf and the serotonin transporter, we explored a val66met x 5-httlpr interaction in a larger sardinia sample (n=2333). |
2010-06-21 |
2023-08-12 |
Not clear |
| Antonio Terracciano, Toshiko Tanaka, Angelina R Sutin, Barbara Deiana, Lenuta Balaci, Serena Sanna, Nazario Olla, Andrea Maschio, Manuela Uda, Luigi Ferrucci, David Schlessinger, Paul T Cost. BDNF Val66Met is associated with introversion and interacts with 5-HTTLPR to influence neuroticism. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 35. issue 5. 2010-06-21. PMID:20042999. |
our findings support the association between the bdnf met variant and introversion and suggest that bdnf interacts with the serotonin transporter gene to influence neuroticism. |
2010-06-21 |
2023-08-12 |
Not clear |
| Yukihiko Shirayama, Shigeyuki Chak. Neurochemistry of the nucleus accumbens and its relevance to depression and antidepressant action in rodents. Current neuropharmacology. vol 4. issue 4. 2010-06-10. PMID:18654637. |
first, we discuss the roles of several neurotransmitters and neuropeptides in the functioning of the nac, including dopamine, glutamate, gamma-aminobutyric acid (gaba), acetylcholine, serotonin, dynorphin, enkephaline, brain-derived neurotrophic factor (bdnf), camp response element-binding protein (creb), melanin-concentrating hormone (mch) and cocaine- and amphetamine-regulated transcript (cart). |
2010-06-10 |
2023-08-12 |
Not clear |
| Raffaella Molteni, Annamaria Cattaneo, Francesca Calabrese, Flavia Macchi, Jocelien D A Olivier, Giorgio Racagni, Bart A Ellenbroek, Massimo Gennarelli, Marco A Riv. Reduced function of the serotonin transporter is associated with decreased expression of BDNF in rodents as well as in humans. Neurobiology of disease. vol 37. issue 3. 2010-06-08. PMID:20034565. |
reduced function of the serotonin transporter is associated with decreased expression of bdnf in rodents as well as in humans. |
2010-06-08 |
2023-08-12 |
human |
| Raffaella Molteni, Annamaria Cattaneo, Francesca Calabrese, Flavia Macchi, Jocelien D A Olivier, Giorgio Racagni, Bart A Ellenbroek, Massimo Gennarelli, Marco A Riv. Reduced function of the serotonin transporter is associated with decreased expression of BDNF in rodents as well as in humans. Neurobiology of disease. vol 37. issue 3. 2010-06-08. PMID:20034565. |
in order to identify the molecular mechanisms that may contribute to the enhanced susceptibility to depression under serotonin transporter (sert) dysfunction, we analyzed the expression of brain-derived neurotrophic factor (bdnf), a key player in neuronal plasticity, which is implicated in the etiology and treatment of depression. |
2010-06-08 |
2023-08-12 |
human |
| Francesca Calabrese, Raffaella Molteni, Annamaria Cattaneo, Flavia Macchi, Giorgio Racagni, Massimo Gennarelli, Bart A Ellenbroek, Marco A Riv. Long-Term duloxetine treatment normalizes altered brain-derived neurotrophic factor expression in serotonin transporter knockout rats through the modulation of specific neurotrophin isoforms. Molecular pharmacology. vol 77. issue 5. 2010-05-28. PMID:20159945. |
because these animals show depression-like behavior, the region and isoform-specific increase of bdnf levels may be a mechanism activated by long-term antidepressant treatment to restore normal plasticity that is defective under genetic dysfunction of the serotonin transporter. |
2010-05-28 |
2023-08-12 |
rat |
| Lea R Dougherty, Daniel N Klein, Eliza Congdon, Turhan Canli, Elizabeth P Hayde. Interaction between 5-HTTLPR and BDNF Val66Met polymorphisms on HPA axis reactivity in preschoolers. Biological psychology. vol 83. issue 2. 2010-05-20. PMID:19914329. |
this study examined whether the interaction between the serotonin transporter promoter region (5-httlpr) and brain-derived neurotrophic factor (bdnf) val66met polymorphisms was associated with hypothalamic-pituitary-adrenal (hpa) axis reactivity to stress. |
2010-05-20 |
2023-08-12 |
Not clear |
| Reiji Yoshimura, Atsuko Ikenouchi-Sugita, Hikaru Hori, Wakako Umene-Nakano, Asuka Katsuki, Kenji Hayashi, Nobuhisa Ueda, Jun Nakamur. Adding a low dose atypical antipsychotic drug to an antidepressant induced a rapid increase of plasma brain-derived neurotrophic factor levels in patients with treatment-resistant depression. Progress in neuro-psychopharmacology & biological psychiatry. vol 34. issue 2. 2010-05-13. PMID:20005280. |
in the present study, we examined the effects of various atypical antipsychotic drugs as adjuvant to antidepressants, including selective serotonin reuptake inhibitors (ssris), serotonin noradrenaline reuptake inhibitors, tricyclic antidepressants and mood stabilizers, on plasma bdnf levels in refractory depressed patients. |
2010-05-13 |
2023-08-12 |
Not clear |
| Mathias Rask-Andersen, Pawel K Olszewski, Allen S Levine, Helgi B Schiöt. Molecular mechanisms underlying anorexia nervosa: focus on human gene association studies and systems controlling food intake. Brain research reviews. vol 62. issue 2. 2010-04-27. PMID:19931559. |
we systematically searched for human genetic studies related to an and grouped data into main categories/systems reflecting their major known roles: (1) systems related to mental disorders (serotonin, brain-derived neurotrophic factor (bdnf), norepinephrine (ne), glutamate (nmda) receptor and sk3 channel, kccn3). |
2010-04-27 |
2023-08-12 |
human |
| T V Zanelati, C Biojone, F A Moreira, F S Guimarães, Sâmia R L Joc. Antidepressant-like effects of cannabidiol in mice: possible involvement of 5-HT1A receptors. British journal of pharmacology. vol 159. issue 1. 2010-04-23. PMID:20002102. |
we also investigated if these responses depended on the activation of 5-ht(1a) receptors and on hippocampal expression of brain-derived neurotrophic factor (bdnf). |
2010-04-23 |
2023-08-12 |
mouse |