| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Tao Yang, Xubo Wang, Lei Liu, Hanwen Chen, Na Wan. Ginkgolide-Platinum(II) Complex GPt(II) Exhibits Therapeutic Effect on Depression in Mice via Upregulation of DA and 5-HT Neurotransmitters. Medical science monitor : international medical journal of experimental and clinical research. vol 26. 2021-02-02. PMID:32484164. |
treatment of mice with gpt(ii) significantly elevated dopamine, bdnf, and serotonin levels in hippocampus tissues. |
2021-02-02 |
2023-08-13 |
mouse |
| Tao Yang, Xubo Wang, Lei Liu, Hanwen Chen, Na Wan. Ginkgolide-Platinum(II) Complex GPt(II) Exhibits Therapeutic Effect on Depression in Mice via Upregulation of DA and 5-HT Neurotransmitters. Medical science monitor : international medical journal of experimental and clinical research. vol 26. 2021-02-02. PMID:32484164. |
the levels of dopamine, serotonin, and bdnf were increased from 187.83±8.53, 289.65±10.76, and 7.98±1.87 ng/g, respectively, in the model group to 657.63±24.47, 720.54±28.09, and 22.56±3.11 ng/g, respectively, in the 12 mg/kg gpt(ii) treatment group. |
2021-02-02 |
2023-08-13 |
mouse |
| Hui-Rong Guo, Bai-Ling Huang, Ya-Li Wang, Yan-Yan Zhang, Quan-Gang Ma, Pei-Pei Lv, Yu-Ming Re. Effect of Escitalopram on Serum GDNF and BDNF Levels and 5-HT Level of Brain Tissue of Obsessive-Compulsive Disorder Rats. Cellular and molecular neurobiology. vol 40. issue 6. 2021-01-22. PMID:31927718. |
effect of escitalopram on serum gdnf and bdnf levels and 5-ht level of brain tissue of obsessive-compulsive disorder rats. |
2021-01-22 |
2023-08-13 |
rat |
| Hui-Rong Guo, Bai-Ling Huang, Ya-Li Wang, Yan-Yan Zhang, Quan-Gang Ma, Pei-Pei Lv, Yu-Ming Re. Effect of Escitalopram on Serum GDNF and BDNF Levels and 5-HT Level of Brain Tissue of Obsessive-Compulsive Disorder Rats. Cellular and molecular neurobiology. vol 40. issue 6. 2021-01-22. PMID:31927718. |
the present study aims to discuss the effect of escitalopram in glial cell line-derived neurotrophic factor (gdnf), brain-derived neurotrophic factor (bdnf) levels, and 5-hydroxytryptamine (5-ht) in obsessive-compulsive disorder rats. |
2021-01-22 |
2023-08-13 |
rat |
| Hui-Rong Guo, Bai-Ling Huang, Ya-Li Wang, Yan-Yan Zhang, Quan-Gang Ma, Pei-Pei Lv, Yu-Ming Re. Effect of Escitalopram on Serum GDNF and BDNF Levels and 5-HT Level of Brain Tissue of Obsessive-Compulsive Disorder Rats. Cellular and molecular neurobiology. vol 40. issue 6. 2021-01-22. PMID:31927718. |
in addition, western blot was used to determine the brain tissue protein levels of gdnf and bdnf and high-performance liquid chromatography + electrochemistry method to determine the 5-ht level of brain tissue. |
2021-01-22 |
2023-08-13 |
rat |
| Hui-Rong Guo, Bai-Ling Huang, Ya-Li Wang, Yan-Yan Zhang, Quan-Gang Ma, Pei-Pei Lv, Yu-Ming Re. Effect of Escitalopram on Serum GDNF and BDNF Levels and 5-HT Level of Brain Tissue of Obsessive-Compulsive Disorder Rats. Cellular and molecular neurobiology. vol 40. issue 6. 2021-01-22. PMID:31927718. |
escitalopram could increase gdnf and bdnf levels and 5-ht content in serum and brain tissue in obsessive-compulsive disorder rats, which contributes to a function on the treatment of obsessive-compulsive disorder. |
2021-01-22 |
2023-08-13 |
rat |
| Brittany E Dong, Hao Chen, Kazuko Sakat. BDNF deficiency and enriched environment treatment affect neurotransmitter gene expression differently across ages. Journal of neurochemistry. vol 154. issue 1. 2020-12-04. PMID:32222968. |
high-throughput quantitative reverse transcription polymerase chain reaction measured expression of 81 genes for dopamine, adrenaline, serotonin, gamma aminobutyric acid, glutamate, acetylcholine, and bdnf systems in the frontal cortex (fc) and hippocampus. |
2020-12-04 |
2023-08-13 |
mouse |
| Christopher B German. The Psilocybin-Telomere Hypothesis: An empirically falsifiable prediction concerning the beneficial neuropsychopharmacological effects of psilocybin on genetic aging. Medical hypotheses. vol 134. 2020-11-23. PMID:31634774. |
in order to substantiate the 'psilocybin-telomere hypothesis' potential neuropsychopharmacological, endocrinological, and genetic mechanisms of action are discussed (e.g., hpa-axis reactivity, hippocampal neurogenesis, neurotropic growth factors such as bdnf, 5-ht |
2020-11-23 |
2023-08-13 |
human |
| Hajer Jasim, Bijar Ghafouri, Björn Gerdle, Britt Hedenberg-Magnusson, Malin Ernber. Altered levels of salivary and plasma pain related markers in temporomandibular disorders. The journal of headache and pain. vol 21. issue 1. 2020-11-23. PMID:32842964. |
the aims of the current study were to compare concentration of glutamate, serotonin (5-ht), nerve growth factor (ngf), brain-derived neurotrophic factor (bdnf), and substance p (sp) in saliva and plasma from a well-defined group of patients with chronic temporomandibular disorders myalgia (tmd-myalgia) with a group of pain-free controls, and further investigate the relationship between these markers and clinical characteristics. |
2020-11-23 |
2023-08-13 |
Not clear |
| Aaveri Sengupta, Ujjal Das, Krishnendu Manna, Sushobhan Biswas, Siddhartha Datta, Amitava Khan, Tuhin Bhattacharya, Samrat Saha, Tapashi Mitra, Swapan Mukherjee, Anup K Sadhu, Suhrita Paul, Saurabh Ghosh, Rakhi Dey Sharma, Sanjit De. An association study of severity of intellectual disability with peripheral biomarkers of disabled children in a rehabilitation home, Kolkata, India. Scientific reports. vol 9. issue 1. 2020-10-28. PMID:31541143. |
the lipid peroxidation of pbmc and rbc membranes, levels of serum glutamate, serotonin, homocysteine, ros, lactate and ldh-a expression increased significantly with severity of id whereas changes in rbc membrane β-actin, serum bdnf, tnf-α and il-6 was found non-significant. |
2020-10-28 |
2023-08-13 |
human |
| Valeria Salinas, Juana Villarroel, Hernán Silva, Luisa Herrera, Sonia Jerez, Alejandra Zazueta, Cristián Montes, Rodrigo Nieto, M Leonor Bustamant. SERT and BDNF polymorphisms interplay on neuroticism in borderline personality disorder. BMC research notes. vol 13. issue 1. 2020-10-26. PMID:32033618. |
we studied 76 patients diagnosed with borderline personality disorder (bpd), characterized by extreme levels of personality traits, especially neuroticism (n), in which we genotyped two polymorphisms, the 5httlpr of the serotonin transporter (sert) gene, and the val66met of the brain-derived neurotrophic factor (bdnf) gene. |
2020-10-26 |
2023-08-13 |
Not clear |
| Yingying Zhou, Xinyi Wang, Yuhang Zhao, Aihua Liu, Tong Zhao, Yuanyuan Zhang, Zhongyan Shan, Weiping Ten. Elevated Thyroid Peroxidase Antibody Increases Risk of Post-partum Depression by Decreasing Prefrontal Cortex BDNF and 5-HT Levels in Mice. Frontiers in cellular neuroscience. vol 10. 2020-10-01. PMID:28119573. |
elevated thyroid peroxidase antibody increases risk of post-partum depression by decreasing prefrontal cortex bdnf and 5-ht levels in mice. |
2020-10-01 |
2023-08-13 |
mouse |
| Yingying Zhou, Xinyi Wang, Yuhang Zhao, Aihua Liu, Tong Zhao, Yuanyuan Zhang, Zhongyan Shan, Weiping Ten. Elevated Thyroid Peroxidase Antibody Increases Risk of Post-partum Depression by Decreasing Prefrontal Cortex BDNF and 5-HT Levels in Mice. Frontiers in cellular neuroscience. vol 10. 2020-10-01. PMID:28119573. |
furthermore, in the prefrontal cortex, the mrna and protein expression levels of brain-derived neurotrophic factor (bdnf) were measured, serotonin (5-ht) levels were measured by ultra-high-performance liquid chromatography-tandem mass-spectrometry (uhplc-ms/ms), and total thyroxine (tt4) levels were determined by elisa. |
2020-10-01 |
2023-08-13 |
mouse |
| Yingying Zhou, Xinyi Wang, Yuhang Zhao, Aihua Liu, Tong Zhao, Yuanyuan Zhang, Zhongyan Shan, Weiping Ten. Elevated Thyroid Peroxidase Antibody Increases Risk of Post-partum Depression by Decreasing Prefrontal Cortex BDNF and 5-HT Levels in Mice. Frontiers in cellular neuroscience. vol 10. 2020-10-01. PMID:28119573. |
compared with the controls, the mice immunized with mtpo-ad displayed depressive behaviors, with a significantly lower sucrose preference (sp) at the 12-h time point and a longer immobility time in the fst and tst, which were accompanied by a lower expression of bdnf and 5-ht but no change in the tt4 concentration in the prefrontal cortex. |
2020-10-01 |
2023-08-13 |
mouse |
| Yingying Zhou, Xinyi Wang, Yuhang Zhao, Aihua Liu, Tong Zhao, Yuanyuan Zhang, Zhongyan Shan, Weiping Ten. Elevated Thyroid Peroxidase Antibody Increases Risk of Post-partum Depression by Decreasing Prefrontal Cortex BDNF and 5-HT Levels in Mice. Frontiers in cellular neuroscience. vol 10. 2020-10-01. PMID:28119573. |
together, these findings suggest that elevated tpoab may increase the risk of subsequent ppd and decrease the concentration of bdnf and 5-ht in the prefrontal cortex. |
2020-10-01 |
2023-08-13 |
mouse |
| Walter J Lukiw, Evgeny I Rogae. Genetics of Aggression in Alzheimer's Disease (AD). Frontiers in aging neuroscience. vol 9. 2020-10-01. PMID:28443016. |
interestingly, (i) the expression of three of these six genes (comt, dbh, nos1) are highly variable; (ii) three of these six genes (comt, dbh, tph1) are involved in da or serotonin metabolism, biosynthesis and/or neurotransmission; and (iii) five of these six genes (ar, bdnf, comt, dbh, nos1) have been implicated in the development, onset and/or propagation of schizophrenia. |
2020-10-01 |
2023-08-13 |
human |
| Yi-Lu Ye, Kai Zhong, Dan-Dan Liu, Jing Xu, Bei-Bei Pan, Xiang Li, Yue-Ping Yu, Qi Zhan. Huanglian-Jie-Du-Tang Extract Ameliorates Depression-Like Behaviors through BDNF-TrkB-CREB Pathway in Rats with Chronic Unpredictable Stress. Evidence-based complementary and alternative medicine : eCAM. vol 2017. 2020-10-01. PMID:28694833. |
5-hydroxytryptamine (5-ht) and dopamine (da) contents, microglial activation, proinflammatory cytokines, and brain derived neurotrophic factor (bdnf), tropomyosin receptor kinases b (trkb), and camp-responsive element binding protein (creb) expression were investigated. |
2020-10-01 |
2023-08-13 |
rat |
| Abdolhossein Bastani, Sadegh Rajabi, Fatemeh Kianimarkan. The Effects of Fasting During Ramadan on the Concentration of Serotonin, Dopamine, Brain-Derived Neurotrophic Factor and Nerve Growth Factor. Neurology international. vol 9. issue 2. 2020-10-01. PMID:28713531. |
the objective was to investigate the plasma levels of serotonin, dopamine, brain-derived neurotrophic factor (bdnf), and nerve growth factor (ngf) in 29 healthy fasted subjects (22 women and 7 men) during the month of fasting in ramadan. |
2020-10-01 |
2023-08-13 |
human |
| Ismo Makkonen, Raili Riikonen, Jyrki T Kuikka, Hannu Kokki, Joseph P Bressler, Cathleen Marshall, Walter E Kaufman. Brain derived neurotrophic factor and serotonin transporter binding as markers of clinical response to fluoxetine therapy in children with autism. Journal of pediatric neurology : JPN. vol 9. issue 1. 2020-10-01. PMID:29056860. |
we examined serum brain derived neurotrophic factor (bdnf) concentrations and serotonin transporter (sert) binding in the medial frontal cortex and midbrain, measured by single photon emission computed tomography (spect) scanning, in a group of 13 autistic children and adolescents (12 males, one female; age 5-16 years), who were treated for six months with fluoxetine at a dose range of 10-40 mg/day. |
2020-10-01 |
2023-08-13 |
human |
| Oleg A Levada, Alexandra S Troya. Poststroke Depression Biomarkers: A Narrative Review. Frontiers in neurology. vol 9. 2020-10-01. PMID:30061860. |
the following molecular candidates can help to differentiate psd patients from non-depressed stroke subjects: decreased serum bdnf concentrations; increased early markers of inflammation (high-sensitivity c-reactive protein, ferritin, neopterin, and glutamate), serum pro-inflammatory cytokines (tnf-α, il-1β, il-6, il-18, ifn-γ), as well as pro-inflammatory/anti-inflammatory ratios (tnf-α/il-10, il-1β/il-10, il-6/il-10, il-18/il-10, ifn-γ/il-10); lowered complement expression; decreased serum vitamin d levels; hypercortisolemia and blunted cortisol awakening response; s/s 5-httlpr, stin2 9/12, and 12/12 genotypes of the serotonin transporter gene slc6a4, 5-htr2a 1438 a/a, and bdnf met/met genotypes; higher slc6a4 promoter and bdnf promoter methylation status. |
2020-10-01 |
2023-08-13 |
human |