| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Chihiro Tanji, Masayuki Hashimoto, Takeo Furuya, Junya Saito, Takuya Miyamoto, Masao Kod. Sigma 1 receptor agonist cutamesine promotes plasticity of serotonergic boutons in lumbar enlargement in spinal cord injured rats. Neuroscience letters. vol 759. 2021-08-06. PMID:34023415. |
immunohistochemistry for bdnf and 5-ht was assessed at four and twelve weeks post-injury in the lumbar spinal cord. |
2021-08-06 |
2023-08-13 |
rat |
| Chihiro Tanji, Masayuki Hashimoto, Takeo Furuya, Junya Saito, Takuya Miyamoto, Masao Kod. Sigma 1 receptor agonist cutamesine promotes plasticity of serotonergic boutons in lumbar enlargement in spinal cord injured rats. Neuroscience letters. vol 759. 2021-08-06. PMID:34023415. |
in sci rats, cutamesine treatment (3.0 mg/kg/day) significantly increased the fluorescence intensity of neuronal bdnf and serotonin boutons in the injured spinal cord compared to saline. |
2021-08-06 |
2023-08-13 |
rat |
| Sanelisiwe P Xhakaza, Leon J Khoza, Advaitaa M Haripershad, Terisha Ghazi, Shanel Dhani, Cosmas Mutsimhu, Molopa J Molopa, Nithia P Madurai, Lorna Madurai, Sanil D Singh, Nirmala D Gopal, Hendrik G Kruger, Thavendran Govender, Anil Chuturgoon, Tricia Naicker, Sooraj Baijnat. Alterations in neurotransmitter levels and transcription factor expression following intranasal buprenorphine administration. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 138. 2021-07-23. PMID:33752062. |
lc-ms was used to quantify bup and neurotransmitters (gaba, glut, da, ne and 5-ht) in the brain, while creb and bdnf gene expression was determined using qpcr. |
2021-07-23 |
2023-08-13 |
rat |
| Anja Dvojkovic, Matea Nikolac Perkovic, Marina Sagud, Gordana Nedic Erjavec, Alma Mihaljevic Peles, Dubravka Svob Strac, Bjanka Vuksan Cusa, Lucija Tudor, Zorana Kusevic, Marcela Konjevod, Maja Zivkovic, Sasa Jevtovic, Nela Piva. Effect of vortioxetine vs. escitalopram on plasma BDNF and platelet serotonin in depressed patients. Progress in neuro-psychopharmacology & biological psychiatry. vol 105. 2021-07-19. PMID:32534176. |
effect of vortioxetine vs. escitalopram on plasma bdnf and platelet serotonin in depressed patients. |
2021-07-19 |
2023-08-13 |
Not clear |
| Anja Dvojkovic, Matea Nikolac Perkovic, Marina Sagud, Gordana Nedic Erjavec, Alma Mihaljevic Peles, Dubravka Svob Strac, Bjanka Vuksan Cusa, Lucija Tudor, Zorana Kusevic, Marcela Konjevod, Maja Zivkovic, Sasa Jevtovic, Nela Piva. Effect of vortioxetine vs. escitalopram on plasma BDNF and platelet serotonin in depressed patients. Progress in neuro-psychopharmacology & biological psychiatry. vol 105. 2021-07-19. PMID:32534176. |
treatment with ssris decrease platelet 5-ht concentration and increase peripheral brain-derived neurotrophic factor (bdnf) levels. |
2021-07-19 |
2023-08-13 |
Not clear |
| Anja Dvojkovic, Matea Nikolac Perkovic, Marina Sagud, Gordana Nedic Erjavec, Alma Mihaljevic Peles, Dubravka Svob Strac, Bjanka Vuksan Cusa, Lucija Tudor, Zorana Kusevic, Marcela Konjevod, Maja Zivkovic, Sasa Jevtovic, Nela Piva. Effect of vortioxetine vs. escitalopram on plasma BDNF and platelet serotonin in depressed patients. Progress in neuro-psychopharmacology & biological psychiatry. vol 105. 2021-07-19. PMID:32534176. |
this longitudinal study aimed to explore and compare the effects of 4-weeks of treatment with vortioxetine and escitalopram on plasma bdnf and platelet 5-ht concentration in patients with major depressive disorder (mdd). |
2021-07-19 |
2023-08-13 |
Not clear |
| Anja Dvojkovic, Matea Nikolac Perkovic, Marina Sagud, Gordana Nedic Erjavec, Alma Mihaljevic Peles, Dubravka Svob Strac, Bjanka Vuksan Cusa, Lucija Tudor, Zorana Kusevic, Marcela Konjevod, Maja Zivkovic, Sasa Jevtovic, Nela Piva. Effect of vortioxetine vs. escitalopram on plasma BDNF and platelet serotonin in depressed patients. Progress in neuro-psychopharmacology & biological psychiatry. vol 105. 2021-07-19. PMID:32534176. |
the results revealed that vortioxetine significantly increased plasma bdnf concentration (p = .018) and significantly decreased platelet 5-ht concentration (p < .001). |
2021-07-19 |
2023-08-13 |
Not clear |
| Anja Dvojkovic, Matea Nikolac Perkovic, Marina Sagud, Gordana Nedic Erjavec, Alma Mihaljevic Peles, Dubravka Svob Strac, Bjanka Vuksan Cusa, Lucija Tudor, Zorana Kusevic, Marcela Konjevod, Maja Zivkovic, Sasa Jevtovic, Nela Piva. Effect of vortioxetine vs. escitalopram on plasma BDNF and platelet serotonin in depressed patients. Progress in neuro-psychopharmacology & biological psychiatry. vol 105. 2021-07-19. PMID:32534176. |
treatment with escitalopram significantly decreased platelet 5-ht concentration (p < .001), but it did not affect plasma bdnf concentration (p = .379). |
2021-07-19 |
2023-08-13 |
Not clear |
| Anja Dvojkovic, Matea Nikolac Perkovic, Marina Sagud, Gordana Nedic Erjavec, Alma Mihaljevic Peles, Dubravka Svob Strac, Bjanka Vuksan Cusa, Lucija Tudor, Zorana Kusevic, Marcela Konjevod, Maja Zivkovic, Sasa Jevtovic, Nela Piva. Effect of vortioxetine vs. escitalopram on plasma BDNF and platelet serotonin in depressed patients. Progress in neuro-psychopharmacology & biological psychiatry. vol 105. 2021-07-19. PMID:32534176. |
response to vortioxetine was not predicted by baseline plasma bdnf or platelet 5-ht concentration, but response to escitalopram was predicted by baseline platelet 5-ht concentration. |
2021-07-19 |
2023-08-13 |
Not clear |
| Basem H Elesawy, Walaa F Alsanie, Mubarak Ali Algahtany, Jawaher M Al-Ashkhari, Aya K Alyarobi, Hussein F Sak. Whole and refined grains change behavior and reduce brain derived neurotrophic factor and neurotrophin-3 in rats. Journal of food biochemistry. 2021-07-19. PMID:34278588. |
after 12 weeks, we measured the hippocampal and prefrontal cortical brain derived neurotrophic factor (bdnf), neurotrophin-3 (nt-3), 5-hydroxytryptamine, dopamine, norepinephrine, malondialdehyde (mda) and reduced glutathione (gsh) levels. |
2021-07-19 |
2023-08-13 |
rat |
| Basem H Elesawy, Walaa F Alsanie, Mubarak Ali Algahtany, Jawaher M Al-Ashkhari, Aya K Alyarobi, Hussein F Sak. Whole and refined grains change behavior and reduce brain derived neurotrophic factor and neurotrophin-3 in rats. Journal of food biochemistry. 2021-07-19. PMID:34278588. |
the rats on a diet of whole and refined grains had low bdnf, nt-3, norepinephrine, dopamine and serotonin significantly (p < .01) in both the hippocampus and prefrontal cortex as compared to control rats. |
2021-07-19 |
2023-08-13 |
rat |
| Hua Jiang, Hong Yin, Lin Wang, Chunzhen Feng, Yang Bai, Dongzong Huang, Qiao Zhang, Hongchen Liu, Yuan H. Memory impairment of chewing-side preference mice is associated with 5-HT-BDNF signal pathway. Molecular and cellular biochemistry. vol 476. issue 1. 2021-07-12. PMID:32989626. |
this study evaluates the behavior changes in mice after the loss of teeth on one side and explores the role of serotonin (5-ht) and brain-derived neurotrophic factor (bdnf) signal pathway within these changes. |
2021-07-12 |
2023-08-13 |
mouse |
| Hua Jiang, Hong Yin, Lin Wang, Chunzhen Feng, Yang Bai, Dongzong Huang, Qiao Zhang, Hongchen Liu, Yuan H. Memory impairment of chewing-side preference mice is associated with 5-HT-BDNF signal pathway. Molecular and cellular biochemistry. vol 476. issue 1. 2021-07-12. PMID:32989626. |
the correlation between csp and brain function changes was validated with changes in 5-ht and bdnf levels. |
2021-07-12 |
2023-08-13 |
mouse |
| Naheed Akhter, Mehir Un Nisa Iqbal, Aliya Maqsood, Safdar Ali Sheikh, Anwar Ali, Taseer Ahmed Kha. Association of BDNF and SERT gene polymorphisms with depression among Pakistani population. Pakistan journal of pharmaceutical sciences. vol 34. issue 1. 2021-07-12. PMID:34248009. |
brain-derived neurotrophic factor (bdnf) and serotonin transporter (sert) is implicated in the adverse life events which lead to depression. |
2021-07-12 |
2023-08-13 |
human |
| Eman Soliman, Nariman Essmat, Mona F Mahmoud, Amr A A Mahmou. Impact of some oral hypoglycemic agents on type 2 diabetes-associated depression and reserpine-induced depression in rats: the role of brain oxidative stress and inflammation. Naunyn-Schmiedeberg's archives of pharmacology. vol 393. issue 8. 2021-07-06. PMID:32077986. |
antidiabetic agents reduced diabetes-associated depression as indicated by the reduction in the immobility time in the forced swim test, elevation of cortical and hippocampal serotonin and brain-derived neurotrophic factor (bdnf), and the increase in serum β-amyloid 1-42 (aβ1-42) levels. |
2021-07-06 |
2023-08-13 |
rat |
| Eman Soliman, Nariman Essmat, Mona F Mahmoud, Amr A A Mahmou. Impact of some oral hypoglycemic agents on type 2 diabetes-associated depression and reserpine-induced depression in rats: the role of brain oxidative stress and inflammation. Naunyn-Schmiedeberg's archives of pharmacology. vol 393. issue 8. 2021-07-06. PMID:32077986. |
although all treatments improved glycemic parameters to similar levels, vildagliptin showed the greatest effect on aβ1-42, serotonin, norepinephrine, and bdnf levels. |
2021-07-06 |
2023-08-13 |
rat |
| Kenichi Fukumoto, Manoela V Fogaça, Rong-Jian Liu, Catharine H Duman, Xiao-Yuan Li, Shigeyuki Chaki, Ronald S Duma. Medial PFC AMPA receptor and BDNF signaling are required for the rapid and sustained antidepressant-like effects of 5-HT Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 45. issue 10. 2021-06-23. PMID:32396921. |
medial pfc ampa receptor and bdnf signaling are required for the rapid and sustained antidepressant-like effects of 5-ht we previously reported that the serotonergic system is important for the antidepressant-like effects of ketamine, a non-competitive n-methyl-d-aspartate receptor antagonist, which produces rapid and long-lasting antidepressant effects in patients with major depressive disorder (mdd). |
2021-06-23 |
2023-08-13 |
Not clear |
| Sirine Abou Al Hassan, Darren Cutinha, Lama Matta. The impact of COMT, BDNF and 5-HTT brain-genes on the development of anorexia nervosa: a systematic review. Eating and weight disorders : EWD. vol 26. issue 5. 2021-06-23. PMID:32783113. |
the aim of this systematic review is to assess the impact of three candidate genes of the brain: catechol-o-methyltransferase, brain-derived neurotrophic factor (bdnf) and serotonin transporter protein, on the susceptibility to an and identify whether a clear connection persists between each of the gene-polymorphisms and an. |
2021-06-23 |
2023-08-13 |
Not clear |
| Ardeshir Akbarabadi, Mitra-Sadat Sadat-Shirazi, Mohamed Kabbaj, Setareh Nouri Zadeh-Tehrani, Solmaz Khalifeh, Fardad Pirri, Mohammad-Reza Zarrindas. Effects of Morphine and Maternal Care on Behaviors and Protein Expression of Male Offspring. Neuroscience. vol 466. 2021-06-22. PMID:33915201. |
to determine the mechanisms underlying the observed behavioral changes, protein levels of acetylated histone h3, bdnf, trk-b, nmda subunits, p-creb, and 5-ht |
2021-06-22 |
2023-08-13 |
rat |
| Nina K Popova, Alexander V Kulikov, Vladimir S Naumenk. Spaceflight and brain plasticity: Spaceflight effects on regional expression of neurotransmitter systems and neurotrophic factors encoding genes. Neuroscience and biobehavioral reviews. vol 119. 2021-06-21. PMID:33086127. |
the review provides converging lines of evidence that: 1) long-term spaceflight affects both principle regulators of brain neuroplasticity - neurotransmitters (5-ht and da) and neurotrophic factors (cdnf, gdnf but not bdnf); 2) 5-ht- (5-ht |
2021-06-21 |
2023-08-13 |
mouse |