| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hang Xu, Xiang Yang Zhang, Wei Wen Wang, Jiesi Wan. Hydroxychloroquine Increased Anxiety-Like Behaviors and Disrupted the Expression of Some Related Genes in the Mouse Brain. Frontiers in pharmacology. vol 12. 2021-05-08. PMID:33953673. |
furthermore, hcq decreased the mrna expression of interleukin-1beta, corticotropin-releasing hormone (crh), a serotonin transporter (slc6a4), and a microglia maker (aif1) in the hippocampus and decreased the mrna expression of brain-derived neurotrophic factor (bdnf) in both the hippocampus and amygdala. |
2021-05-08 |
2023-08-13 |
mouse |
| Merve Demirbugen Oz, Bora Baskak, Zuhal Uckun, Nazan Yuce Artun, Hatice Ozdemir, Tugba Kizil Ozel, Halise Devrimci Ozguven, H Sinan Suze. Association between serotonin 2A receptor (HTR2A), serotonin transporter (SLC6A4) and brain-derived neurotrophic factor (BDNF) gene polymorphisms and citalopram/sertraline induced sexual dysfunction in MDD patients. The pharmacogenomics journal. vol 20. issue 3. 2021-05-07. PMID:31792367. |
association between serotonin 2a receptor (htr2a), serotonin transporter (slc6a4) and brain-derived neurotrophic factor (bdnf) gene polymorphisms and citalopram/sertraline induced sexual dysfunction in mdd patients. |
2021-05-07 |
2023-08-13 |
human |
| Merve Demirbugen Oz, Bora Baskak, Zuhal Uckun, Nazan Yuce Artun, Hatice Ozdemir, Tugba Kizil Ozel, Halise Devrimci Ozguven, H Sinan Suze. Association between serotonin 2A receptor (HTR2A), serotonin transporter (SLC6A4) and brain-derived neurotrophic factor (BDNF) gene polymorphisms and citalopram/sertraline induced sexual dysfunction in MDD patients. The pharmacogenomics journal. vol 20. issue 3. 2021-05-07. PMID:31792367. |
the present study aimed to determine the relationship between serotonin-2a receptor (htr2a) gene -1438a/g and 102t/c polymorphisms, serotonin transporter gene (slc6a4) 5-htt-linked polymorphic region (5-httlpr) insertion/deletion variant and brain-derived neurotrophic factor (bdnf) gene val66met polymorphisms and the occurrence of sd adverse effect in major depressive disorder patients treated with citalopram (cit) or sertraline (sert). |
2021-05-07 |
2023-08-13 |
human |
| Madhusmita P Sahu, Yago Pazos-Boubeta, Anna Steinzeig, Katja Kaurinkoski, Michela Palmisano, Olgierd Borowecki, Timo Petteri Piepponen, Eero Castré. Depletion of TrkB Receptors From Adult Serotonergic Neurons Increases Brain Serotonin Levels, Enhances Energy Metabolism and Impairs Learning and Memory. Frontiers in molecular neuroscience. vol 14. 2021-05-04. PMID:33935645. |
neurotrophin brain-derived neurotrophic factor (bdnf) and neurotransmitter serotonin (5-ht) regulate each other and have been implicated in several neuronal mechanisms, including neuroplasticity. |
2021-05-04 |
2023-08-13 |
mouse |
| Jing Si, Haidi Zhang, Lina Zhu, Aiguo Che. The Relationship between Overweight/Obesity and Executive Control in College Students: The Mediating Effect of BDNF and 5-HT. Life (Basel, Switzerland). vol 11. issue 4. 2021-05-02. PMID:33916706. |
the relationship between overweight/obesity and executive control in college students: the mediating effect of bdnf and 5-ht. |
2021-05-02 |
2023-08-13 |
human |
| Jing Si, Haidi Zhang, Lina Zhu, Aiguo Che. The Relationship between Overweight/Obesity and Executive Control in College Students: The Mediating Effect of BDNF and 5-HT. Life (Basel, Switzerland). vol 11. issue 4. 2021-05-02. PMID:33916706. |
the main aim of this study was to explore the association between overweight/obesity and executive control (ec) in young adults, and to further analyze the mediating effect of brain-derived neurotrophic factor (bdnf) and serotonin (5-hydroxytryptamine (5-ht)) on the relationship between overweight/obesity and ec. |
2021-05-02 |
2023-08-13 |
human |
| Jing Si, Haidi Zhang, Lina Zhu, Aiguo Che. The Relationship between Overweight/Obesity and Executive Control in College Students: The Mediating Effect of BDNF and 5-HT. Life (Basel, Switzerland). vol 11. issue 4. 2021-05-02. PMID:33916706. |
the ec of the participants was then estimated using the flanker task, while their serum bdnf levels and 5-ht levels were measured using an enzyme-linked immunosorbent assay (elisa) kit. |
2021-05-02 |
2023-08-13 |
human |
| Jing Si, Haidi Zhang, Lina Zhu, Aiguo Che. The Relationship between Overweight/Obesity and Executive Control in College Students: The Mediating Effect of BDNF and 5-HT. Life (Basel, Switzerland). vol 11. issue 4. 2021-05-02. PMID:33916706. |
finally, the multiple intermediary models in spss were used to analyze the mediating effect of 5-ht and bdnf between overweight/obesity and ec. |
2021-05-02 |
2023-08-13 |
human |
| Kacper Łoś, Napoleon Waszkiewic. Biological Markers in Anxiety Disorders. Journal of clinical medicine. vol 10. issue 8. 2021-05-02. PMID:33920547. |
in the blood, in turn, we can distinguish serotonin, brain-derived serum neurotrophic factor (bdnf), cortisol, and microrna. |
2021-05-02 |
2023-08-13 |
Not clear |
| Erin Yiqing Lu, Posen Lee, Shuhe Cai, Wendy Wing Yan So, Bacon Fung Leung Ng, Mark P Jensen, Wai Ming Cheung, Hector W H Tsan. Qigong for the treatment of depressive symptoms: Preliminary evidence of neurobiological mechanisms. International journal of geriatric psychiatry. vol 35. issue 11. 2021-04-19. PMID:32662069. |
here, we sought to evaluate the effects of qigong on serotonin, cortisol, and brain-derived neurotropic factors (bdnf) levels and test their roles as potential mediators of the effects of qigong on depressive symptoms. |
2021-04-19 |
2023-08-13 |
Not clear |
| Jie Wang, Yajun Wang, Xudong Xu, Sheng Peng, Feng Xu, Peirong Li. Use of Various Doses of S-Ketamine in Treatment of Depression and Pain in Cervical Carcinoma Patients with Mild/Moderate Depression After Laparoscopic Total Hysterectomy. Medical science monitor : international medical journal of experimental and clinical research. vol 26. 2021-04-14. PMID:32565534. |
serum levels of bdnf and 5-ht were measured. |
2021-04-14 |
2023-08-13 |
Not clear |
| Jie Wang, Yajun Wang, Xudong Xu, Sheng Peng, Feng Xu, Peirong Li. Use of Various Doses of S-Ketamine in Treatment of Depression and Pain in Cervical Carcinoma Patients with Mild/Moderate Depression After Laparoscopic Total Hysterectomy. Medical science monitor : international medical journal of experimental and clinical research. vol 26. 2021-04-14. PMID:32565534. |
the high-dose s-ketamine group showed significantly higher serum bdnf and 5-ht levels at 1 day and 3 days after surgery. |
2021-04-14 |
2023-08-13 |
Not clear |
| Chengping Luo, Huimin Fan, Shaojun Li, Yuling Zo. Therapeutic of Candesartan and Music Therapy in Diabetic Retinopathy with Depression in Rats. Evidence-based complementary and alternative medicine : eCAM. vol 2021. 2021-04-10. PMID:33833815. |
compared with the control group, the apoptosis of retinal cells was significantly higher, the contents of 5-ht, da, and ne in the hippocampus were significantly lower, ang ii level in peripheral blood was significantly higher, and the expression of bdnf and c-fos in the hippocampus decreased significantly in the model group. |
2021-04-10 |
2023-08-13 |
rat |
| Jo-Eun Jeong, Sekye Jeon, Jae Sang Han, Eun Young Cho, Kyung Sue Hong, Shi Nae Park, Jung Jin Ki. The Mediating Effect of Psychological Distress on the Association between BDNF, 5-HTTLPR, and Tinnitus Severity. Psychiatry investigation. vol 18. issue 3. 2021-04-09. PMID:33685039. |
to investigate the association between genetic polymorphisms of brain-derived neurotrophic factor (bdnf) or serotonin transporter gene-linked polymorphic region (5-httlpr) and tinnitus, and the mediating effects of psychological distress on this association. |
2021-04-09 |
2023-08-13 |
Not clear |
| József Bódis, Endre Sulyok, Ákos Várnagy, Miklós Koppán, Gábor Kovács . Investigations of follicular fluid biomarkers in patients undergoing Orvosi hetilap. vol 162. issue 14. 2021-04-02. PMID:33784245. |
such associations for brain-derived neurotrophic factor (bdnf) could not be found, but bdnf and serotonin in the follicular fluid were closely related (r = 0.377, p<0.040) suggesting that the feed-forward regulation of these neurohormones is activated at ovarian level. |
2021-04-02 |
2023-08-13 |
Not clear |
| Tin-Tin Win-Shwe, Chaw Kyi-Tha-Thu, Yuji Fujitani, Shinji Tsukahara, Seishiro Hiran. Perinatal Exposure to Diesel Exhaust-Origin Secondary Organic Aerosol Induces Autism-Like Behavior in Rats. International journal of molecular sciences. vol 22. issue 2. 2021-03-30. PMID:33430368. |
serotonin receptor (5-ht(5b)) and brain-derived neurotrophic factor (bdnf) mrnas were downregulated whereas interleukin 1 β (il-β) and heme oxygenase 1 (ho-1) mrnas were upregulated in the prefrontal cortex of male and female rats exposed to de-soa. |
2021-03-30 |
2023-08-13 |
rat |
| Ashif Iqubal, Mansoor Ali Syed, Abul Kalam Najmi, Faizul Azam, George E Barreto, Mohammad Kashif Iqubal, Javed Ali, Syed Ehtaishamul Haqu. Nano-engineered nerolidol loaded lipid carrier delivery system attenuates cyclophosphamide neurotoxicity - Probable role of NLRP3 inflammasome and caspase-1. Experimental neurology. vol 334. 2021-03-10. PMID:32941795. |
biochemical analysis showed increased levels of mda, tnf-α, il-6, il-1β, acetylcholine esterase, bdnf, 5-ht and dopamine, and reduced levels of sod, cat, gsh, il-10, along with significant behavioral dysfunction in cyclophosphamide-treated animals. |
2021-03-10 |
2023-08-13 |
mouse |
| Jay Belsky, Xiaoya Zhang, Kristina Sayle. Differential susceptibility 2.0: Are the same children affected by different experiences and exposures? Development and psychopathology. 2021-02-26. PMID:33634774. |
analyses validating the new method indicated, as predicted, that (a) the quantity-of-care effect applied principally to children from more socioeconomically advantaged families and that (b) being highly susceptible to both, one or neither childcare effect varied as a function of a three-gene, polygenic-plasticity score (serotonin transporter linked polymorphic region [5-httlpr], dopamine receptor d4 [drd4], brain-derived neurotrophic factor [bdnf]) in a dose-response manner (i.e., 2>1>0). |
2021-02-26 |
2023-08-13 |
human |
| Chiao-Yin Sun, Jian-Ri Li, Ya-Yu Wang, Shih-Yi Lin, Yen-Chuan Ou, Cheng-Jui Lin, Jiaan-Der Wang, Su-Lan Liao, Chun-Jung Che. p-Cresol Sulfate Caused Behavior Disorders and Neurodegeneration in Mice with Unilateral Nephrectomy Involving Oxidative Stress and Neuroinflammation. International journal of molecular sciences. vol 21. issue 18. 2021-02-25. PMID:32932690. |
circulating brain-derived neurotrophic factors (bdnf) and serotonin were decreased in association with increased corticosterone and repressor element-1 silencing transcription factor (rest), regulators involved in neurological disorders. |
2021-02-25 |
2023-08-13 |
mouse |
| Wen Shan Yang, Zhen-Guo Shi, Xian-Zhe Dong, Ping Liu, Meng-Li Chen, Yuan H. Involvement of 5-HT-BDNF signaling axis in mediating synergistic antidepressant-like effects after combined administration of two oligosaccharide esters. Food science & nutrition. vol 9. issue 2. 2021-02-19. PMID:33598202. |
potential mechanisms of depression involving herbal medicines and their specific compounds include elevated 5-ht level and downstream bdnf pathway. |
2021-02-19 |
2023-08-13 |
Not clear |