| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Aysu Kilic, Savas Ustunova, Birsen Elibol, Huri Bulut, Ismail Meral, Gulderen Sahi. Angiotensin IV improves spatial memory in streptozotocin‑induced diabetic rats by reducing oxidative stress and altering BDNF levels. Acta neurobiologiae experimentalis. vol 81. issue 2. 2021-06-28. PMID:34170263. |
these findings suggest that peripheral administration of ang iv ameliorated spatial memory in diabetic rats by decreasing hippocampal oxidative stress and bdnf levels. |
2021-06-28 |
2023-08-13 |
rat |
| Gavin M Meade, Lily S Charron, Lantz W Kilburn, Zhe Pei, Hoau-Yan Wang, Siobhan Robinso. A model of negative emotional contagion between male-female rat dyads: Effects of voluntary exercise on stress-induced behavior and BDNF-TrkB signaling. Physiology & behavior. vol 234. 2021-06-25. PMID:33321142. |
we found that pair housing a healthy male with a stressed female led to emotional contagion; males gained less body weight, were anhedonic, demonstrated heightened anxiety-like behavior, had lower serum brain-derived neurotrophic factor (bdnf) levels, had decreased hippocampal bdnf-stimulated tyrosine receptor kinase b (trkb) signaling and had increased pro-inflammatory cytokine expression in the hippocampus. |
2021-06-25 |
2023-08-13 |
human |
| Gavin M Meade, Lily S Charron, Lantz W Kilburn, Zhe Pei, Hoau-Yan Wang, Siobhan Robinso. A model of negative emotional contagion between male-female rat dyads: Effects of voluntary exercise on stress-induced behavior and BDNF-TrkB signaling. Physiology & behavior. vol 234. 2021-06-25. PMID:33321142. |
specifically, stress-paired, exercised rats showed less depressive-like behavior, had partially preserved hippocampal bdnf-stimulated trkb signaling, had normalized serum bdnf concentration, and had hippocampal cytokine and immediate early gene levels that were equivalent to controls. |
2021-06-25 |
2023-08-13 |
human |
| Vanessa Angonesi Zborowski, Suélen Osório Heck, Luiza Souza Marques, Nícolas Klummer Bastos, Cristina Wayne Nogueir. Memory impairment and depressive-like phenotype are accompanied by downregulation of hippocampal insulin and BDNF signaling pathways in prediabetic mice. Physiology & behavior. vol 237. 2021-06-25. PMID:33545209. |
memory impairment and depressive-like phenotype are accompanied by downregulation of hippocampal insulin and bdnf signaling pathways in prediabetic mice. |
2021-06-25 |
2023-08-13 |
mouse |
| Vanessa Angonesi Zborowski, Suélen Osório Heck, Luiza Souza Marques, Nícolas Klummer Bastos, Cristina Wayne Nogueir. Memory impairment and depressive-like phenotype are accompanied by downregulation of hippocampal insulin and BDNF signaling pathways in prediabetic mice. Physiology & behavior. vol 237. 2021-06-25. PMID:33545209. |
this study investigates if memory impairment and depressive-like phenotype are accompanied by the hippocampal insulin and bdnf signaling in prediabetic mice. |
2021-06-25 |
2023-08-13 |
mouse |
| Vanessa Angonesi Zborowski, Suélen Osório Heck, Luiza Souza Marques, Nícolas Klummer Bastos, Cristina Wayne Nogueir. Memory impairment and depressive-like phenotype are accompanied by downregulation of hippocampal insulin and BDNF signaling pathways in prediabetic mice. Physiology & behavior. vol 237. 2021-06-25. PMID:33545209. |
the molecular findings indicate the downregulation of hippocampal insulin and bdnf signaling in prediabetic mice. |
2021-06-25 |
2023-08-13 |
mouse |
| Hui Yao, Hui Shen, Hao Yu, Changliang Wang, Runtao Ding, Xinze Lan, Dilichati Tash, Xu Wu, Xiaolong Wang, Guohua Zhan. Chronic ethanol exposure induced depressive-like behavior in male C57BL/6 N mice by downregulating GluA1. Physiology & behavior. vol 234. 2021-06-25. PMID:33713693. |
we confirmed that 90- and 180-day ethanol exposure can lead to depressive-like mouse behavior, cell apoptosis, neuronal degeneration, a reduction in glua1 and brain-derived neurotrophic factor (bdnf) expression, and an increase in il-6 and il-1β in the mouse hippocampus. |
2021-06-25 |
2023-08-13 |
mouse |
| Roshanak Roustazade, Maryam Radahmadi, Yeganeh Yazdan. Therapeutic effects of saffron extract on different memory types, anxiety, and hippocampal BDNF and TNF-α gene expressions in sub-chronically stressed rats. Nutritional neuroscience. 2021-06-24. PMID:34165393. |
therapeutic effects of saffron extract on different memory types, anxiety, and hippocampal bdnf and tnf-α gene expressions in sub-chronically stressed rats. |
2021-06-24 |
2023-08-13 |
rat |
| Xiaohui Jiang, Lina Chen, Zhongyuan Zheng, Ying Chen, Xiaogang Weng, Yuan Guo, Kai Li, Ting Yang, Shuiqing Qu, Hui Liu, Yujie Li, Xiaoxin Zh. Synergistic Effect of Combined Artesunate and Tetramethylpyrazine in Experimental Cerebral Malaria. ACS infectious diseases. vol 6. issue 9. 2021-06-23. PMID:32786270. |
this combination downregulated the expression of adhesion molecules and sequestration of parasitized red blood cells (prbcs), increased cerebral blood flow, nerve growth factor (b-ngf), vascular endothelial growth factor a (vegf-a), and neurotrophin (brain-derived neurotrophic factor (bdnf), neurotrophic factor-3 (nt-3)) levels, and alleviated hippocampal neuronal damage and astrocyte activation. |
2021-06-23 |
2023-08-13 |
mouse |
| Kellie S Gross, Randie L Alf, Tiffany R Polzin, Karyn M Fric. 17β-estradiol activation of dorsal hippocampal TrkB is independent of increased mature BDNF expression and is required for enhanced memory consolidation in female mice. Psychoneuroendocrinology. vol 125. 2021-06-22. PMID:33352471. |
17β-estradiol activation of dorsal hippocampal trkb is independent of increased mature bdnf expression and is required for enhanced memory consolidation in female mice. |
2021-06-22 |
2023-08-13 |
mouse |
| Samaneh Shamsipour, Gholamreza Sharifi, Farzaneh Taghia. Impact of interval training with probiotic (L. plantarum / Bifidobacterium bifidum) on passive avoidance test, ChAT and BDNF in the hippocampus of rats with Alzheimer's disease. Neuroscience letters. vol 756. 2021-06-22. PMID:33974953. |
impact of interval training with probiotic (l. plantarum / bifidobacterium bifidum) on passive avoidance test, chat and bdnf in the hippocampus of rats with alzheimer's disease. |
2021-06-22 |
2023-08-13 |
rat |
| Samaneh Shamsipour, Gholamreza Sharifi, Farzaneh Taghia. Impact of interval training with probiotic (L. plantarum / Bifidobacterium bifidum) on passive avoidance test, ChAT and BDNF in the hippocampus of rats with Alzheimer's disease. Neuroscience letters. vol 756. 2021-06-22. PMID:33974953. |
to take this line of research further, this study was aimed at investigating the impact of moderate-intensity interval training (miit) with a combined administration of lactobacillus plantarum and bifidobacterium bifidum (probiotic, brob) on the passive avoidance test (shuttle box), choline acetyltransferase (chat) and the brain derived neurotrophic factor (bdnf) in the hippocampus of a rat model of ad. |
2021-06-22 |
2023-08-13 |
rat |
| Samaneh Shamsipour, Gholamreza Sharifi, Farzaneh Taghia. Impact of interval training with probiotic (L. plantarum / Bifidobacterium bifidum) on passive avoidance test, ChAT and BDNF in the hippocampus of rats with Alzheimer's disease. Neuroscience letters. vol 756. 2021-06-22. PMID:33974953. |
bdnf and chat in the hippocampus were measured by real time pcr (rt-pcr) and immunohistochemistry (ihc), respectively. |
2021-06-22 |
2023-08-13 |
rat |
| Ge Wang, Hongyang Zhang, Jiancong Sun, Yuwei Zhang, Fen He, Juntao Zo. Cyclosporin A impairs neurogenesis and cognitive abilities in brain development via the IFN-γ-Shh-BDNF pathway. International immunopharmacology. vol 96. 2021-06-22. PMID:33993101. |
however, the shh pathway receptor agonist sag could block the impairment of cognitive ability and the decrease of hippocampal neurogenesis and brain-derived neurotrophic factor (bdnf) level induced by csa. |
2021-06-22 |
2023-08-13 |
Not clear |
| Min-Tae Jeon, Gyeong Joon Moon, Sehwan Kim, Minji Choi, Yong-Seok Oh, Dong Woon Kim, Hyung-Jun Kim, Kea Joo Lee, Youngshik Choe, Chang Man Ha, Il-Sung Jang, Michiko Nakamura, Catriona McLean, Won-Suk Chung, Won-Ho Shin, Seok-Geun Lee, Sang Ryong Ki. Neurotrophic interactions between neurons and astrocytes following AAV1-Rheb(S16H) transduction in the hippocampus in vivo. British journal of pharmacology. vol 177. issue 3. 2021-06-21. PMID:31658360. |
we recently reported that aav1-rheb(s16h) transduction could protect hippocampal neurons through the induction of brain-derived neurotrophic factor (bdnf) in the rat hippocampus in vivo. |
2021-06-21 |
2023-08-13 |
rat |
| Min-Tae Jeon, Gyeong Joon Moon, Sehwan Kim, Minji Choi, Yong-Seok Oh, Dong Woon Kim, Hyung-Jun Kim, Kea Joo Lee, Youngshik Choe, Chang Man Ha, Il-Sung Jang, Michiko Nakamura, Catriona McLean, Won-Suk Chung, Won-Ho Shin, Seok-Geun Lee, Sang Ryong Ki. Neurotrophic interactions between neurons and astrocytes following AAV1-Rheb(S16H) transduction in the hippocampus in vivo. British journal of pharmacology. vol 177. issue 3. 2021-06-21. PMID:31658360. |
it is still unclear how neuronal bdnf produced by aav1-rheb(s16h) transduction induces neuroprotective effects in the hippocampus and whether its up-regulation contributes to the enhance of a neuroprotective system in the adult brain. |
2021-06-21 |
2023-08-13 |
rat |
| Luiza P Géa, Eduarda D da Rosa, Bruna S Panizzutti, Érica Z de Aguiar, Larissa F de Oliveira, Pamela Ferrari, Angelo Piato, Rosane Gomez, Rafael Colombo, Adriane R Ros. Reduction of hippocampal IL-6 levels in LPS-injected rats following acute exendin-4 treatment. Naunyn-Schmiedeberg's archives of pharmacology. vol 393. issue 7. 2021-06-21. PMID:32363414. |
brain-derived neurotrophic factor (bdnf), thiobarbituric acid reactive species (tbars), and interleukin (il)-6 were quantified in the serum and hippocampus. |
2021-06-21 |
2023-08-13 |
rat |
| Luiza P Géa, Eduarda D da Rosa, Bruna S Panizzutti, Érica Z de Aguiar, Larissa F de Oliveira, Pamela Ferrari, Angelo Piato, Rosane Gomez, Rafael Colombo, Adriane R Ros. Reduction of hippocampal IL-6 levels in LPS-injected rats following acute exendin-4 treatment. Naunyn-Schmiedeberg's archives of pharmacology. vol 393. issue 7. 2021-06-21. PMID:32363414. |
bdnf hippocampal levels seemed to be increased in the lps+ex-4 0.5 group compared with lps+saline (p > 0.05). |
2021-06-21 |
2023-08-13 |
rat |
| Kohei Takahashi, Kazuhiro Kurokawa, Kazuya Miyagawa, Atsumi Mochida-Saito, Yukio Nemoto, Hiroyuki Iwasa, Osamu Nakagawasai, Takeshi Tadano, Hiroshi Takeda, Minoru Tsuj. Antidementia effects of Enterococcus faecalis 2001 are associated with enhancement of hippocampal neurogenesis via the ERK-CREB-BDNF pathway in olfactory bulbectomized mice. Physiology & behavior. vol 223. 2021-06-21. PMID:32502526. |
moreover, ef-2001 also recovered the reductions in p-erk1/2, p-creb, bdnf and dcx levels and in neurogenesis observed in the hippocampus of obx mice. |
2021-06-21 |
2023-08-13 |
mouse |
| Hamideh Bashiri, Mohsen Enayati, Alireza Bashiri, Ali-Akbar Salar. Swimming exercise improves cognitive and behavioral disorders in male NMRI mice with sporadic Alzheimer-like disease. Physiology & behavior. vol 223. 2021-06-21. PMID:32522682. |
to understand the possible mechanisms, amyloid-β (aβ)-42, brain-derived neurotrophic factor (bdnf), glutamate, malondialdehyde (mda), tumor-necrosis-factor (tnf)-α, and interleukin (il)-6 levels were measured in the hippocampus. |
2021-06-21 |
2023-08-13 |
mouse |