| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Alessandra Tamburella, Vincenzo Micale, Gian Marco Leggio, Filippo Drag. The beta3 adrenoceptor agonist, amibegron (SR58611A) counteracts stress-induced behavioral and neurochemical changes. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 20. issue 10. 2010-12-22. PMID:20537869. |
compared to the control groups, both stressor procedures increased the immobility time in the fst and reduced hippocampal bdnf and bcl-2/bax ratio proteins expression, which were counteracted by amibegron (5 and 10mg/kg) treatment. |
2010-12-22 |
2023-08-12 |
rat |
| Hee Ra Park, Mikyung Park, Jehun Choi, Kun-Young Park, Hae Young Chung, Jaewon Le. A high-fat diet impairs neurogenesis: involvement of lipid peroxidation and brain-derived neurotrophic factor. Neuroscience letters. vol 482. issue 3. 2010-12-22. PMID:20670674. |
hfd also increased the level of malondialdehyde (mda) and decreased the level of brain-derived neurotrophic factor (bdnf) in the hippocampus. |
2010-12-22 |
2023-08-12 |
mouse |
| Hee Ra Park, Mikyung Park, Jehun Choi, Kun-Young Park, Hae Young Chung, Jaewon Le. A high-fat diet impairs neurogenesis: involvement of lipid peroxidation and brain-derived neurotrophic factor. Neuroscience letters. vol 482. issue 3. 2010-12-22. PMID:20670674. |
the present data indicate that a hfd impairs hippocampal neurogenesis and npcs proliferation through increased lipid peroxidation and decreased bdnf. |
2010-12-22 |
2023-08-12 |
mouse |
| J Wong, T M Hyde, H L Cassano, A Deep-Soboslay, J E Kleinman, C Shannon Weicker. Promoter specific alterations of brain-derived neurotrophic factor mRNA in schizophrenia. Neuroscience. vol 169. issue 3. 2010-12-16. PMID:20553817. |
we next determined the regional specificity of the bdnf mrna reduction by measuring bdnf transcripts in the parietal cortex and hippocampus and found no significant changes. |
2010-12-16 |
2023-08-12 |
Not clear |
| J Wong, T M Hyde, H L Cassano, A Deep-Soboslay, J E Kleinman, C Shannon Weicker. Promoter specific alterations of brain-derived neurotrophic factor mRNA in schizophrenia. Neuroscience. vol 169. issue 3. 2010-12-16. PMID:20553817. |
moreover, we found significant reductions in bdnf transcripts ii-ix and iv-ix in the parietal cortex and vi-ix in the hippocampus of patients with schizophrenia who did not have a history of treatment with antidepressants. |
2010-12-16 |
2023-08-12 |
Not clear |
| A B Klein, M A Santini, S Aznar, G M Knudsen, M Rio. Changes in 5-HT2A-mediated behavior and 5-HT2A- and 5-HT1A receptor binding and expression in conditional brain-derived neurotrophic factor knock-out mice. Neuroscience. vol 169. issue 3. 2010-12-16. PMID:20576498. |
additionally, 5-ht(1a) receptor binding was decreased in hippocampus of bdnf mutants, but unchanged in frontal cortex. |
2010-12-16 |
2023-08-12 |
mouse |
| Michael E Hopkins, David J Bucc. BDNF expression in perirhinal cortex is associated with exercise-induced improvement in object recognition memory. Neurobiology of learning and memory. vol 94. issue 2. 2010-12-13. PMID:20601027. |
hippocampal and perirhinal cortex tissue was collected to determine whether the relationship between bdnf and cognitive performance extends to this non-spatial and non-hippocampal-dependent task. |
2010-12-13 |
2023-08-12 |
rat |
| Michael E Hopkins, David J Bucc. BDNF expression in perirhinal cortex is associated with exercise-induced improvement in object recognition memory. Neurobiology of learning and memory. vol 94. issue 2. 2010-12-13. PMID:20601027. |
there was a trend for a negative relationship between anxiety-like behavior and hippocampal bdnf. |
2010-12-13 |
2023-08-12 |
rat |
| Michael E Hopkins, David J Bucc. BDNF expression in perirhinal cortex is associated with exercise-induced improvement in object recognition memory. Neurobiology of learning and memory. vol 94. issue 2. 2010-12-13. PMID:20601027. |
these are the first data demonstrating that region-specific changes in bdnf protein levels are correlated with exercise-induced improvements in non-spatial memory, mediated by structures outside the hippocampus and are consistent with the theory that, with regard to object recognition, the anxiolytic and cognitive effects of exercise may be mediated through separable mechanisms. |
2010-12-13 |
2023-08-12 |
rat |
| Lulu Y Chen, Christopher S Rex, Danielle T Pham, Gary Lynch, Christine M Gal. BDNF signaling during learning is regionally differentiated within hippocampus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 45. 2010-12-13. PMID:21068315. |
bdnf signaling during learning is regionally differentiated within hippocampus. |
2010-12-13 |
2023-08-12 |
rat |
| Lulu Y Chen, Christopher S Rex, Danielle T Pham, Gary Lynch, Christine M Gal. BDNF signaling during learning is regionally differentiated within hippocampus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 45. 2010-12-13. PMID:21068315. |
a previous study provided evidence that unsupervised learning of a novel environment is accompanied by activation of the trkb receptor for brain-derived neurotrophic factor (bdnf) in hippocampal field ca1b of adult rats. |
2010-12-13 |
2023-08-12 |
rat |
| Li Sui, Bao-Ming L. Effects of perinatal hypothyroidism on regulation of reelin and brain-derived neurotrophic factor gene expression in rat hippocampus: Role of DNA methylation and histone acetylation. Steroids. vol 75. issue 12. 2010-12-08. PMID:20600205. |
the present study investigated the role of dna methylaion and histone acetylation in the effects of perinatal hypothyroidism on regulation of reelin and brain-derived neurotrophic factor (bdnf) gene expression in rat hippocampus. |
2010-12-08 |
2023-08-12 |
rat |
| Li Sui, Bao-Ming L. Effects of perinatal hypothyroidism on regulation of reelin and brain-derived neurotrophic factor gene expression in rat hippocampus: Role of DNA methylation and histone acetylation. Steroids. vol 75. issue 12. 2010-12-08. PMID:20600205. |
the findings indicated that the activities of dna methyltransferase (dnmt), methylated reelin and bdnf genes were up-regulated, whereas, the activities of histone acetylases (hat), the levels of global acetylated histone 3 (h3) and global acetylated histone 4 (h4), and acetylated h3, acetylated h4 at reelin promoter and at bdnf gene promoter for exon ii were down-regulated in the hippocampus at the developmental stage of the hypothyroid animals. |
2010-12-08 |
2023-08-12 |
rat |
| Li Sui, Bao-Ming L. Effects of perinatal hypothyroidism on regulation of reelin and brain-derived neurotrophic factor gene expression in rat hippocampus: Role of DNA methylation and histone acetylation. Steroids. vol 75. issue 12. 2010-12-08. PMID:20600205. |
these results suggest that epigenetic modification of chromatin might underlie the mechanisms of hypothyroidism-induced down-regulation of reelin and bdnf gene expression in developmental rat hippocampus. |
2010-12-08 |
2023-08-12 |
rat |
| Yuan Hu, Ping Liu, Dai-Hong Guo, Khalid Rahman, Dong-Xiao Wang, Ting-Ting Xi. Antidepressant effects of the extract YZ-50 from Polygala tenuifolia in chronic mild stress treated rats and its possible mechanisms. Pharmaceutical biology. vol 48. issue 7. 2010-12-07. PMID:20645779. |
furthermore, we tested the hypothesis that the capacity of yz-50 to reverse the harmful effects of cms is relative to the hypothalamo-pituitary-adrenal (hpa) system and brain-derived neurotrophic factor (bdnf) in the hippocampus. |
2010-12-07 |
2023-08-12 |
rat |
| Yuan Hu, Ping Liu, Dai-Hong Guo, Khalid Rahman, Dong-Xiao Wang, Ting-Ting Xi. Antidepressant effects of the extract YZ-50 from Polygala tenuifolia in chronic mild stress treated rats and its possible mechanisms. Pharmaceutical biology. vol 48. issue 7. 2010-12-07. PMID:20645779. |
in addition, cms significantly decreased hippocampal bdnf mrna levels. |
2010-12-07 |
2023-08-12 |
rat |
| Yuan Hu, Ping Liu, Dai-Hong Guo, Khalid Rahman, Dong-Xiao Wang, Ting-Ting Xi. Antidepressant effects of the extract YZ-50 from Polygala tenuifolia in chronic mild stress treated rats and its possible mechanisms. Pharmaceutical biology. vol 48. issue 7. 2010-12-07. PMID:20645779. |
however, yz-50 counteracted a decrease in hippocampal bdnf mrna caused by cms. |
2010-12-07 |
2023-08-12 |
rat |
| Nicholas J Rich, Jacob W Van Landingham, Silvia Figueiroa, Rohit Seth, Rikki S Corniola, Cathy W Levenso. Chronic caloric restriction reduces tissue damage and improves spatial memory in a rat model of traumatic brain injury. Journal of neuroscience research. vol 88. issue 13. 2010-12-06. PMID:20544832. |
western analysis, used to examine the expression of proteins that play a role in neuronal survival, revealed significant increases in brain-derived neurotrophic factor (bdnf) in the cortical region around the site of injury and in the hippocampus in cr rats after injury. |
2010-12-06 |
2023-08-12 |
rat |
| Yousheng Jia, Christine M Gall, Gary Lync. Presynaptic BDNF promotes postsynaptic long-term potentiation in the dorsal striatum. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 43. 2010-11-30. PMID:20980601. |
brain-derived neurotrophic factor (bdnf) facilitates the formation of long-term potentiation (ltp) in hippocampus, but whether this involves release from presynaptic versus postsynaptic pools is unclear. |
2010-11-30 |
2023-08-12 |
mouse |
| Claudia Aguirre, Anusha Jayaraman, Christian Pike, Michel Baudr. Progesterone inhibits estrogen-mediated neuroprotection against excitotoxicity by down-regulating estrogen receptor-β. Journal of neurochemistry. vol 115. issue 5. 2010-11-29. PMID:20977477. |
we recently reported that a 4-h treatment of cultured hippocampal slices with p4 following a prolonged (20 h) treatment with e2 eliminated estrogenic neuroprotection against nmda toxicity and induction of brain-derived neurotrophic factor (bdnf) expression. |
2010-11-29 |
2023-08-12 |
mouse |