| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A B Klein, M A Santini, S Aznar, G M Knudsen, M Rio. Changes in 5-HT2A-mediated behavior and 5-HT2A- and 5-HT1A receptor binding and expression in conditional brain-derived neurotrophic factor knock-out mice. Neuroscience. vol 169. issue 3. 2010-12-16. PMID:20576498. |
additionally, 5-ht(1a) receptor binding was decreased in hippocampus of bdnf mutants, but unchanged in frontal cortex. |
2010-12-16 |
2023-08-12 |
mouse |
| Michael E Hopkins, David J Bucc. BDNF expression in perirhinal cortex is associated with exercise-induced improvement in object recognition memory. Neurobiology of learning and memory. vol 94. issue 2. 2010-12-13. PMID:20601027. |
hippocampal and perirhinal cortex tissue was collected to determine whether the relationship between bdnf and cognitive performance extends to this non-spatial and non-hippocampal-dependent task. |
2010-12-13 |
2023-08-12 |
rat |
| Michael E Hopkins, David J Bucc. BDNF expression in perirhinal cortex is associated with exercise-induced improvement in object recognition memory. Neurobiology of learning and memory. vol 94. issue 2. 2010-12-13. PMID:20601027. |
there was a trend for a negative relationship between anxiety-like behavior and hippocampal bdnf. |
2010-12-13 |
2023-08-12 |
rat |
| Michael E Hopkins, David J Bucc. BDNF expression in perirhinal cortex is associated with exercise-induced improvement in object recognition memory. Neurobiology of learning and memory. vol 94. issue 2. 2010-12-13. PMID:20601027. |
these are the first data demonstrating that region-specific changes in bdnf protein levels are correlated with exercise-induced improvements in non-spatial memory, mediated by structures outside the hippocampus and are consistent with the theory that, with regard to object recognition, the anxiolytic and cognitive effects of exercise may be mediated through separable mechanisms. |
2010-12-13 |
2023-08-12 |
rat |
| Lulu Y Chen, Christopher S Rex, Danielle T Pham, Gary Lynch, Christine M Gal. BDNF signaling during learning is regionally differentiated within hippocampus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 45. 2010-12-13. PMID:21068315. |
bdnf signaling during learning is regionally differentiated within hippocampus. |
2010-12-13 |
2023-08-12 |
rat |
| Lulu Y Chen, Christopher S Rex, Danielle T Pham, Gary Lynch, Christine M Gal. BDNF signaling during learning is regionally differentiated within hippocampus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 45. 2010-12-13. PMID:21068315. |
a previous study provided evidence that unsupervised learning of a novel environment is accompanied by activation of the trkb receptor for brain-derived neurotrophic factor (bdnf) in hippocampal field ca1b of adult rats. |
2010-12-13 |
2023-08-12 |
rat |
| Li Sui, Bao-Ming L. Effects of perinatal hypothyroidism on regulation of reelin and brain-derived neurotrophic factor gene expression in rat hippocampus: Role of DNA methylation and histone acetylation. Steroids. vol 75. issue 12. 2010-12-08. PMID:20600205. |
the present study investigated the role of dna methylaion and histone acetylation in the effects of perinatal hypothyroidism on regulation of reelin and brain-derived neurotrophic factor (bdnf) gene expression in rat hippocampus. |
2010-12-08 |
2023-08-12 |
rat |
| Li Sui, Bao-Ming L. Effects of perinatal hypothyroidism on regulation of reelin and brain-derived neurotrophic factor gene expression in rat hippocampus: Role of DNA methylation and histone acetylation. Steroids. vol 75. issue 12. 2010-12-08. PMID:20600205. |
the findings indicated that the activities of dna methyltransferase (dnmt), methylated reelin and bdnf genes were up-regulated, whereas, the activities of histone acetylases (hat), the levels of global acetylated histone 3 (h3) and global acetylated histone 4 (h4), and acetylated h3, acetylated h4 at reelin promoter and at bdnf gene promoter for exon ii were down-regulated in the hippocampus at the developmental stage of the hypothyroid animals. |
2010-12-08 |
2023-08-12 |
rat |
| Li Sui, Bao-Ming L. Effects of perinatal hypothyroidism on regulation of reelin and brain-derived neurotrophic factor gene expression in rat hippocampus: Role of DNA methylation and histone acetylation. Steroids. vol 75. issue 12. 2010-12-08. PMID:20600205. |
these results suggest that epigenetic modification of chromatin might underlie the mechanisms of hypothyroidism-induced down-regulation of reelin and bdnf gene expression in developmental rat hippocampus. |
2010-12-08 |
2023-08-12 |
rat |
| Yuan Hu, Ping Liu, Dai-Hong Guo, Khalid Rahman, Dong-Xiao Wang, Ting-Ting Xi. Antidepressant effects of the extract YZ-50 from Polygala tenuifolia in chronic mild stress treated rats and its possible mechanisms. Pharmaceutical biology. vol 48. issue 7. 2010-12-07. PMID:20645779. |
furthermore, we tested the hypothesis that the capacity of yz-50 to reverse the harmful effects of cms is relative to the hypothalamo-pituitary-adrenal (hpa) system and brain-derived neurotrophic factor (bdnf) in the hippocampus. |
2010-12-07 |
2023-08-12 |
rat |
| Yuan Hu, Ping Liu, Dai-Hong Guo, Khalid Rahman, Dong-Xiao Wang, Ting-Ting Xi. Antidepressant effects of the extract YZ-50 from Polygala tenuifolia in chronic mild stress treated rats and its possible mechanisms. Pharmaceutical biology. vol 48. issue 7. 2010-12-07. PMID:20645779. |
in addition, cms significantly decreased hippocampal bdnf mrna levels. |
2010-12-07 |
2023-08-12 |
rat |
| Yuan Hu, Ping Liu, Dai-Hong Guo, Khalid Rahman, Dong-Xiao Wang, Ting-Ting Xi. Antidepressant effects of the extract YZ-50 from Polygala tenuifolia in chronic mild stress treated rats and its possible mechanisms. Pharmaceutical biology. vol 48. issue 7. 2010-12-07. PMID:20645779. |
however, yz-50 counteracted a decrease in hippocampal bdnf mrna caused by cms. |
2010-12-07 |
2023-08-12 |
rat |
| Nicholas J Rich, Jacob W Van Landingham, Silvia Figueiroa, Rohit Seth, Rikki S Corniola, Cathy W Levenso. Chronic caloric restriction reduces tissue damage and improves spatial memory in a rat model of traumatic brain injury. Journal of neuroscience research. vol 88. issue 13. 2010-12-06. PMID:20544832. |
western analysis, used to examine the expression of proteins that play a role in neuronal survival, revealed significant increases in brain-derived neurotrophic factor (bdnf) in the cortical region around the site of injury and in the hippocampus in cr rats after injury. |
2010-12-06 |
2023-08-12 |
rat |
| Yousheng Jia, Christine M Gall, Gary Lync. Presynaptic BDNF promotes postsynaptic long-term potentiation in the dorsal striatum. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 43. 2010-11-30. PMID:20980601. |
brain-derived neurotrophic factor (bdnf) facilitates the formation of long-term potentiation (ltp) in hippocampus, but whether this involves release from presynaptic versus postsynaptic pools is unclear. |
2010-11-30 |
2023-08-12 |
mouse |
| Claudia Aguirre, Anusha Jayaraman, Christian Pike, Michel Baudr. Progesterone inhibits estrogen-mediated neuroprotection against excitotoxicity by down-regulating estrogen receptor-β. Journal of neurochemistry. vol 115. issue 5. 2010-11-29. PMID:20977477. |
we recently reported that a 4-h treatment of cultured hippocampal slices with p4 following a prolonged (20 h) treatment with e2 eliminated estrogenic neuroprotection against nmda toxicity and induction of brain-derived neurotrophic factor (bdnf) expression. |
2010-11-29 |
2023-08-12 |
mouse |
| Yusuke Tozuka, Mami Kumon, Etsuko Wada, Masafumi Onodera, Hideki Mochizuki, Keiji Wad. Maternal obesity impairs hippocampal BDNF production and spatial learning performance in young mouse offspring. Neurochemistry international. vol 57. issue 3. 2010-11-04. PMID:20538025. |
maternal obesity impairs hippocampal bdnf production and spatial learning performance in young mouse offspring. |
2010-11-04 |
2023-08-12 |
mouse |
| Yusuke Tozuka, Mami Kumon, Etsuko Wada, Masafumi Onodera, Hideki Mochizuki, Keiji Wad. Maternal obesity impairs hippocampal BDNF production and spatial learning performance in young mouse offspring. Neurochemistry international. vol 57. issue 3. 2010-11-04. PMID:20538025. |
hfd offspring had less brain-derived neurotrophic factor (bdnf) in the hippocampus than nd offspring. |
2010-11-04 |
2023-08-12 |
mouse |
| Yusuke Tozuka, Mami Kumon, Etsuko Wada, Masafumi Onodera, Hideki Mochizuki, Keiji Wad. Maternal obesity impairs hippocampal BDNF production and spatial learning performance in young mouse offspring. Neurochemistry international. vol 57. issue 3. 2010-11-04. PMID:20538025. |
this study, using a mouse model, indicates that diet-induced maternal obesity impairs hippocampal bdnf production and spatial cognitive function in young offspring, possibly due to their metabolic and oxidative changes. |
2010-11-04 |
2023-08-12 |
mouse |
| Jong Min Kim, Dong Hyun Kim, Se Jin Park, Dong Hyun Park, Seo Yun Jung, Hyoung Ja Kim, Yong Sup Lee, Changbae Jin, Jong Hoon Ry. The n-butanolic extract of Opuntia ficus-indica var. saboten enhances long-term memory in the passive avoidance task in mice. Progress in neuro-psychopharmacology & biological psychiatry. vol 34. issue 6. 2010-11-02. PMID:20493231. |
western blotting revealed that the expression levels of brain-derived neurotrophic factor (bdnf), phosphorylated camp response element binding-protein (pcreb), and phosphorylated extracellular signal-regulated kinase (perk) 1/2 were significantly increased in hippocampal tissue after 7 days of bof administration (p<0.05). |
2010-11-02 |
2023-08-12 |
mouse |
| Wen-Jing Li, Hui Yu, Jian-Min Yang, Jing Gao, Hong Jiang, Min Feng, Yu-Xia Zhao, Zhe-Yu Che. Anxiolytic effect of music exposure on BDNFMet/Met transgenic mice. Brain research. vol 1347. 2010-11-02. PMID:20515664. |
moreover, in contrast to white noise exposure, bdnf expression levels in the prefrontal cortex (pfc), amygdala and hippocampus were significantly increased in music-exposed adult bdnf(met/met) mice. |
2010-11-02 |
2023-08-12 |
mouse |