| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Min Kyoo Shin, Hong Gi Kim, Kil Lyong Ki. A novel trimeric peptide, Neuropep-1-stimulating brain-derived neurotrophic factor expression in rat brain improves spatial learning and memory as measured by the Y-maze and Morris water maze. Journal of neurochemistry. vol 116. issue 2. 2011-01-20. PMID:21044076. |
these results showed neuropep-1 injection improved slm performance with increase of bdnf and trkb expression, activation of trkb downstream signals in rat hippocampus compared with the control group. |
2011-01-20 |
2023-08-12 |
rat |
| Marianne H Larsen, Jens D Mikkelsen, Anders Hay-Schmidt, Carmen Sand. Regulation of brain-derived neurotrophic factor (BDNF) in the chronic unpredictable stress rat model and the effects of chronic antidepressant treatment. Journal of psychiatric research. vol 44. issue 13. 2011-01-12. PMID:20172535. |
bdnf mrna levels in the ventral and dorsal hippocampus were assessed by in situ hybridization. |
2011-01-12 |
2023-08-12 |
rat |
| Marianne H Larsen, Jens D Mikkelsen, Anders Hay-Schmidt, Carmen Sand. Regulation of brain-derived neurotrophic factor (BDNF) in the chronic unpredictable stress rat model and the effects of chronic antidepressant treatment. Journal of psychiatric research. vol 44. issue 13. 2011-01-12. PMID:20172535. |
exposure to cus was not correlated with a decrease but rather with an increase in bdnf mrna expression in both the dentate gyrus of the dorsal hippocampus and the ca3 region of the ventral hippocampus indicating that there is no simple link between depression-like behaviors per se and brain bdnf levels in rats. |
2011-01-12 |
2023-08-12 |
rat |
| Marianne H Larsen, Jens D Mikkelsen, Anders Hay-Schmidt, Carmen Sand. Regulation of brain-derived neurotrophic factor (BDNF) in the chronic unpredictable stress rat model and the effects of chronic antidepressant treatment. Journal of psychiatric research. vol 44. issue 13. 2011-01-12. PMID:20172535. |
however, a significant increase in bdnf mrna levels in the dentate gyrus of the dorsal hippocampus correlated with chronic antidepressant treatment emphasizing a role for bdnf in the mechanisms underlying antidepressant activity. |
2011-01-12 |
2023-08-12 |
rat |
| James J Valdes, Franchesca M Ramirez, Barbara Juarez, Ophelia I Week. Lithium enhances cortical mRNA expression in ovariectomized C57BL/6J mice. Acta neurobiologiae experimentalis. vol 70. issue 3. 2011-01-07. PMID:20871648. |
results indicate that licl-treated bovx mice show enhanced cortical increases in mrna expression of er-alpha, nr1, bcl-2, bdnf, and camkii-alpha; hippocampal mrna showed no changes. |
2011-01-07 |
2023-08-12 |
mouse |
| Jennifer Y F Lau, David Goldman, Beata Buzas, Colin Hodgkinson, Ellen Leibenluft, Eric Nelson, Lindsey Sankin, Daniel S Pine, Monique Erns. BDNF gene polymorphism (Val66Met) predicts amygdala and anterior hippocampus responses to emotional faces in anxious and depressed adolescents. NeuroImage. vol 53. issue 3. 2011-01-03. PMID:19931400. |
bdnf gene polymorphism (val66met) predicts amygdala and anterior hippocampus responses to emotional faces in anxious and depressed adolescents. |
2011-01-03 |
2023-08-12 |
human |
| Samantha Tang, Rita Machaalani, Karen A Water. Immunolocalization of pro- and mature-brain derived neurotrophic factor (BDNF) and receptor TrkB in the human brainstem and hippocampus. Brain research. vol 1354. 2011-01-03. PMID:20673758. |
immunolocalization of pro- and mature-brain derived neurotrophic factor (bdnf) and receptor trkb in the human brainstem and hippocampus. |
2011-01-03 |
2023-08-12 |
human |
| Samantha Tang, Rita Machaalani, Karen A Water. Immunolocalization of pro- and mature-brain derived neurotrophic factor (BDNF) and receptor TrkB in the human brainstem and hippocampus. Brain research. vol 1354. 2011-01-03. PMID:20673758. |
this study provides a detailed account of the distribution and localization of both pro- and mature-recombinant human (rh) forms of bdnf, and of trkb in the human infant brainstem and hippocampus, and qualitatively compares this expression to that seen in the human adult. |
2011-01-03 |
2023-08-12 |
human |
| Samantha Tang, Rita Machaalani, Karen A Water. Immunolocalization of pro- and mature-brain derived neurotrophic factor (BDNF) and receptor TrkB in the human brainstem and hippocampus. Brain research. vol 1354. 2011-01-03. PMID:20673758. |
we conclude that bdnf and trkb play important roles in controlling respiration, movement, balance and feeding in the brainstem and that the trkb receptor is the most age-sensitive component of this system, especially in the hippocampus. |
2011-01-03 |
2023-08-12 |
human |
| Unn Kristin Haukvik, Peter Saetre, Thomas McNeil, Petr S Bjerkan, Ole A Andreassen, Thomas Werge, Erik G Jönsson, Ingrid Agart. An exploratory model for G x E interaction on hippocampal volume in schizophrenia; obstetric complications and hypoxia-related genes. Progress in neuro-psychopharmacology & biological psychiatry. vol 34. issue 7. 2010-12-29. PMID:20638435. |
we investigated putative independent and interaction effects of severe hypoxia-related ocs and variation in four hypoxia-regulated schizophrenia susceptibility genes (bdnf, dtnbp1, grm3 and nrg1) on hippocampal volume in schizophrenia patients and healthy controls. |
2010-12-29 |
2023-08-12 |
Not clear |
| Georgia E Hodes, Tiffany E Hill-Smith, Irwin Luck. Fluoxetine treatment induces dose dependent alterations in depression associated behavior and neural plasticity in female mice. Neuroscience letters. vol 484. issue 1. 2010-12-28. PMID:20692322. |
the other half of the hippocampus and the frontal cortex was removed and examined for bdnf levels. |
2010-12-28 |
2023-08-12 |
mouse |
| Georgia E Hodes, Tiffany E Hill-Smith, Irwin Luck. Fluoxetine treatment induces dose dependent alterations in depression associated behavior and neural plasticity in female mice. Neuroscience letters. vol 484. issue 1. 2010-12-28. PMID:20692322. |
chronic treatment with 5 and 10mg/kg of fluoxetine significantly increased cell proliferation and bdnf levels in the hippocampus. |
2010-12-28 |
2023-08-12 |
mouse |
| Georgia E Hodes, Tiffany E Hill-Smith, Irwin Luck. Fluoxetine treatment induces dose dependent alterations in depression associated behavior and neural plasticity in female mice. Neuroscience letters. vol 484. issue 1. 2010-12-28. PMID:20692322. |
behavioral measures in the nih test correlated with bdnf levels in the frontal cortex but not in the hippocampus or with cell proliferation in the hippocampus. |
2010-12-28 |
2023-08-12 |
mouse |
| Georgia E Hodes, Tiffany E Hill-Smith, Irwin Luck. Fluoxetine treatment induces dose dependent alterations in depression associated behavior and neural plasticity in female mice. Neuroscience letters. vol 484. issue 1. 2010-12-28. PMID:20692322. |
these data suggest that females require high doses of fluoxetine for behavioral efficacy regardless of elevations of neurogenesis and bdnf mobilization in the hippocampus. |
2010-12-28 |
2023-08-12 |
mouse |
| Alessandra Tamburella, Vincenzo Micale, Gian Marco Leggio, Filippo Drag. The beta3 adrenoceptor agonist, amibegron (SR58611A) counteracts stress-induced behavioral and neurochemical changes. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 20. issue 10. 2010-12-22. PMID:20537869. |
to this purpose, the expression levels of the hippocampal cyclic adenosine monophosphate (camp)-response element binding protein (creb), brain-derived neurotrophic factor (bdnf), b-cell lymphoma-2 (bcl-2) and bax proteins were assessed, by using western blot analysis, in rats tested in the forced swim test (fst). |
2010-12-22 |
2023-08-12 |
rat |
| Alessandra Tamburella, Vincenzo Micale, Gian Marco Leggio, Filippo Drag. The beta3 adrenoceptor agonist, amibegron (SR58611A) counteracts stress-induced behavioral and neurochemical changes. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 20. issue 10. 2010-12-22. PMID:20537869. |
compared to the control groups, both stressor procedures increased the immobility time in the fst and reduced hippocampal bdnf and bcl-2/bax ratio proteins expression, which were counteracted by amibegron (5 and 10mg/kg) treatment. |
2010-12-22 |
2023-08-12 |
rat |
| Hee Ra Park, Mikyung Park, Jehun Choi, Kun-Young Park, Hae Young Chung, Jaewon Le. A high-fat diet impairs neurogenesis: involvement of lipid peroxidation and brain-derived neurotrophic factor. Neuroscience letters. vol 482. issue 3. 2010-12-22. PMID:20670674. |
hfd also increased the level of malondialdehyde (mda) and decreased the level of brain-derived neurotrophic factor (bdnf) in the hippocampus. |
2010-12-22 |
2023-08-12 |
mouse |
| Hee Ra Park, Mikyung Park, Jehun Choi, Kun-Young Park, Hae Young Chung, Jaewon Le. A high-fat diet impairs neurogenesis: involvement of lipid peroxidation and brain-derived neurotrophic factor. Neuroscience letters. vol 482. issue 3. 2010-12-22. PMID:20670674. |
the present data indicate that a hfd impairs hippocampal neurogenesis and npcs proliferation through increased lipid peroxidation and decreased bdnf. |
2010-12-22 |
2023-08-12 |
mouse |
| J Wong, T M Hyde, H L Cassano, A Deep-Soboslay, J E Kleinman, C Shannon Weicker. Promoter specific alterations of brain-derived neurotrophic factor mRNA in schizophrenia. Neuroscience. vol 169. issue 3. 2010-12-16. PMID:20553817. |
we next determined the regional specificity of the bdnf mrna reduction by measuring bdnf transcripts in the parietal cortex and hippocampus and found no significant changes. |
2010-12-16 |
2023-08-12 |
Not clear |
| J Wong, T M Hyde, H L Cassano, A Deep-Soboslay, J E Kleinman, C Shannon Weicker. Promoter specific alterations of brain-derived neurotrophic factor mRNA in schizophrenia. Neuroscience. vol 169. issue 3. 2010-12-16. PMID:20553817. |
moreover, we found significant reductions in bdnf transcripts ii-ix and iv-ix in the parietal cortex and vi-ix in the hippocampus of patients with schizophrenia who did not have a history of treatment with antidepressants. |
2010-12-16 |
2023-08-12 |
Not clear |