| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Marco Assunção, Maria J Santos-Marques, Félix Carvalho, José P Andrad. Green tea averts age-dependent decline of hippocampal signaling systems related to antioxidant defenses and survival. Free radical biology & medicine. vol 48. issue 6. 2010-06-30. PMID:20064606. |
at completion of the specified time points, the glutathione levels and antioxidant enzyme activities, the activation of the transcription factors cyclic amp response element-binding (creb) and nuclear factor-kappab (nf-kappab, p50 and p65 subunits), and the levels of brain-derived neurotrophic factor (bdnf) and b-cell lymphoma-2 (bcl-2) were measured in hippocampal formations. |
2010-06-30 |
2023-08-12 |
rat |
| Talita Tuon, Samira S Valvassori, Jéssica Lopes-Borges, Gabriel R Fries, Luciano A Silva, Flavio Kapczinski, João Quevedo, Ricardo A Pinh. Effects of moderate exercise on cigarette smoke exposure-induced hippocampal oxidative stress values and neurological behaviors in mice. Neuroscience letters. vol 475. issue 1. 2010-06-30. PMID:20303389. |
in addition, the brain-derived neurotrophic factor (bdnf) levels were measured in the hippocampus samples. |
2010-06-30 |
2023-08-12 |
mouse |
| Talita Tuon, Samira S Valvassori, Jéssica Lopes-Borges, Gabriel R Fries, Luciano A Silva, Flavio Kapczinski, João Quevedo, Ricardo A Pinh. Effects of moderate exercise on cigarette smoke exposure-induced hippocampal oxidative stress values and neurological behaviors in mice. Neuroscience letters. vol 475. issue 1. 2010-06-30. PMID:20303389. |
there was an increase in the levels of superoxide, tbars and of protein carbonyl and a decreased in bdnf levels in the hippocampus of rats exposed to cigarette smoke and cigarette smoke plus exercise. |
2010-06-30 |
2023-08-12 |
mouse |
| Talita Tuon, Samira S Valvassori, Jéssica Lopes-Borges, Gabriel R Fries, Luciano A Silva, Flavio Kapczinski, João Quevedo, Ricardo A Pinh. Effects of moderate exercise on cigarette smoke exposure-induced hippocampal oxidative stress values and neurological behaviors in mice. Neuroscience letters. vol 475. issue 1. 2010-06-30. PMID:20303389. |
in conclusion, we observed that physical training improves the oxidative stress parameters, but does not alter depressive-like behavior neither prevent the decreases in bdnf levels in hippocampus induced by cigarette smoke. |
2010-06-30 |
2023-08-12 |
mouse |
| N C Berchtold, N Castello, C W Cotma. Exercise and time-dependent benefits to learning and memory. Neuroscience. vol 167. issue 3. 2010-06-29. PMID:20219647. |
assessment of the time course of hippocampal bdnf availability following exercise revealed significant elevations of bdnf immediately after the exercise period (186% of sedentary levels) and at 1 and 2 weeks after exercise ended, with levels returning to baseline by 3-4 weeks. |
2010-06-29 |
2023-08-12 |
mouse |
| Yan Hou, Marwa A Aboukhatwa, De-Liang Lei, Kebreten Manaye, Ikhlas Khan, Yuan Lu. Anti-depressant natural flavonols modulate BDNF and beta amyloid in neurons and hippocampus of double TgAD mice. Neuropharmacology. vol 58. issue 6. 2010-06-23. PMID:19917299. |
anti-depressant natural flavonols modulate bdnf and beta amyloid in neurons and hippocampus of double tgad mice. |
2010-06-23 |
2023-08-12 |
mouse |
| Yan Hou, Marwa A Aboukhatwa, De-Liang Lei, Kebreten Manaye, Ikhlas Khan, Yuan Lu. Anti-depressant natural flavonols modulate BDNF and beta amyloid in neurons and hippocampus of double TgAD mice. Neuropharmacology. vol 58. issue 6. 2010-06-23. PMID:19917299. |
in addition, enhanced bdnf expression and reduction of abeta oligomers was confirmed in hippocampus of the double transgenic mice administered with flavonol, which correlates with cognitive improvement behaviors in these mice. |
2010-06-23 |
2023-08-12 |
mouse |
| Neha J Patel, Michael J Chen, Amelia A Russo-Neustad. Norepinephrine and nitric oxide promote cell survival signaling in hippocampal neurons. European journal of pharmacology. vol 633. issue 1-3. 2010-06-22. PMID:20149790. |
we assessed pro-survival outcomes following the application of norepinephrine or the noradrenergic partial agonist, clonidine, a general nitric oxide synthase inhibitor and no donor, using a cell survival assay and quantitative western blotting of the survival signaling molecules, bdnf, p-creb, p-akt, and p-mapk in hippocampal neuronal lysates. |
2010-06-22 |
2023-08-12 |
Not clear |
| Jinsook Kim, Karen Gale, Alexei Kondratye. Effects of repeated minimal electroshock seizures on NGF, BDNF and FGF-2 protein in the rat brain during postnatal development. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 28. issue 3. 2010-06-21. PMID:20170723. |
protein levels were measured 6h after the last ecs using western blotting for fgf-2 in rhinal cortex, elisa for bdnf and ngf in hippocampus, and ngf in frontal cortex. |
2010-06-21 |
2023-08-12 |
human |
| Jinsook Kim, Karen Gale, Alexei Kondratye. Effects of repeated minimal electroshock seizures on NGF, BDNF and FGF-2 protein in the rat brain during postnatal development. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 28. issue 3. 2010-06-21. PMID:20170723. |
the repeated seizures during p7-13 affected only bdnf protein, causing a significant elevation of 40% in hippocampus over sham-treated controls. |
2010-06-21 |
2023-08-12 |
human |
| Jinsook Kim, Karen Gale, Alexei Kondratye. Effects of repeated minimal electroshock seizures on NGF, BDNF and FGF-2 protein in the rat brain during postnatal development. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 28. issue 3. 2010-06-21. PMID:20170723. |
in p14-20 pups, the repeated seizures resulted in a significant increase in bdnf in hippocampus (162% over controls) and fgf-2 in rhinal cortex (34% over controls), while ngf protein did not show a significant change in either hippocampus or frontal cortex. |
2010-06-21 |
2023-08-12 |
human |
| Kelli A McDowell, Ashley N Hutchinson, Sarah J E Wong-Goodrich, Matthew M Presby, Dan Su, Ramona M Rodriguiz, Krystal C Law, Christina L Williams, William C Wetsel, Anne E Wes. Reduced cortical BDNF expression and aberrant memory in Carf knock-out mice. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 22. 2010-06-21. PMID:20519520. |
intriguingly, carf ko mice have selectively reduced expression of bdnf exon iv-containing mrna transcripts and bdnf protein in the cerebral cortex, whereas bdnf levels in the hippocampus and striatum remain unchanged, implicating carf as a brain region-selective regulator of bdnf expression. |
2010-06-21 |
2023-08-12 |
mouse |
| R Molteni, F Calabrese, S Chourbaji, C Brandwein, G Racagni, P Gass, M A Riv. Depression-prone mice with reduced glucocorticoid receptor expression display an altered stress-dependent regulation of brain-derived neurotrophic factor and activity-regulated cytoskeleton-associated protein. Journal of psychopharmacology (Oxford, England). vol 24. issue 4. 2010-06-18. PMID:19074532. |
steady-state levels of bdnf mrna were unchanged in hippocampus while up-regulated in frontal lobe of gr(+/-) mice. |
2010-06-18 |
2023-08-12 |
mouse |
| R Molteni, F Calabrese, S Chourbaji, C Brandwein, G Racagni, P Gass, M A Riv. Depression-prone mice with reduced glucocorticoid receptor expression display an altered stress-dependent regulation of brain-derived neurotrophic factor and activity-regulated cytoskeleton-associated protein. Journal of psychopharmacology (Oxford, England). vol 24. issue 4. 2010-06-18. PMID:19074532. |
following exposure to an acute stress, increased processing from pro- to mature bdnf was observed in hippocampal synaptosomes of wild-type mice, but not in gr mutants. |
2010-06-18 |
2023-08-12 |
mouse |
| Jamie Peters, Laura M Dieppa-Perea, Loyda M Melendez, Gregory J Quir. Induction of fear extinction with hippocampal-infralimbic BDNF. Science (New York, N.Y.). vol 328. issue 5983. 2010-06-16. PMID:20522777. |
rats failing to learn extinction showed reduced bdnf in hippocampal inputs to the il mpfc, and augmenting bdnf in this pathway prevented extinction failure. |
2010-06-16 |
2023-08-12 |
rat |
| Johannes Fuss, Nada M-B Ben Abdallah, Miriam A Vogt, Chadi Touma, Pier Giorgio Pacifici, Rupert Palme, Veit Witzemann, Rainer Hellweg, Peter Gas. Voluntary exercise induces anxiety-like behavior in adult C57BL/6J mice correlating with hippocampal neurogenesis. Hippocampus. vol 20. issue 3. 2010-06-14. PMID:19452518. |
we did not observe any antidepressant effect of running despite a significant increase of hippocampal neurogenesis and bdnf. |
2010-06-14 |
2023-08-12 |
mouse |
| Vera Sterlemann, Gerhard Rammes, Miriam Wolf, Claudia Liebl, Karin Ganea, Marianne B Müller, Mathias V Schmid. Chronic social stress during adolescence induces cognitive impairment in aged mice. Hippocampus. vol 20. issue 4. 2010-06-14. PMID:19489003. |
further, we observed a decrease of hippocampal bdnf mrna and synaptophysin immunoreactivity, suggesting plasticity and structural alterations in formerly stressed mice. |
2010-06-14 |
2023-08-12 |
mouse |
| Ning Li, Geng-tao Li. The novel squamosamide derivative FLZ enhances BDNF/TrkB/CREB signaling and inhibits neuronal apoptosis in APP/PS1 mice. Acta pharmacologica Sinica. vol 31. issue 3. 2010-06-14. PMID:20154710. |
the aim of this study was to study the effects of compound flz, a novel cyclic derivative of squamosamide from annona glabra, on brain-derived neurotrophic factor (bdnf)/tropomyosin receptor kinase b (trkb)/camp response element-binding protein (creb) signaling and neuronal apoptosis in the hippocampus of the amyloid precursor protein (app)/presenilin-1 (ps1) double transgenic mice. |
2010-06-14 |
2023-08-12 |
mouse |
| Rachael W Sirianni, Peter Olausson, Amy S Chiu, Jane R Taylor, W Mark Saltzma. The behavioral and biochemical effects of BDNF containing polymers implanted in the hippocampus of rats. Brain research. vol 1321. 2010-06-09. PMID:20096671. |
the behavioral and biochemical effects of bdnf containing polymers implanted in the hippocampus of rats. |
2010-06-09 |
2023-08-12 |
rat |
| Rachael W Sirianni, Peter Olausson, Amy S Chiu, Jane R Taylor, W Mark Saltzma. The behavioral and biochemical effects of BDNF containing polymers implanted in the hippocampus of rats. Brain research. vol 1321. 2010-06-09. PMID:20096671. |
in this work, we engineered degradable, injectable alginate microspheres and non-degradable, implantable poly(ethylene vinyl acetate) matrices to continuously deliver bdnf to the dorsal hippocampus of rats for two days or more than a week, respectively. |
2010-06-09 |
2023-08-12 |
rat |