| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| b' S Wagner, O Baskaya, N Dahmen, K Lieb, A Tadi\\xc4\\x8. Modulatory role of the brain-derived neurotrophic factor Val66Met polymorphism on the effects of serious life events on impulsive aggression in borderline personality disorder. Genes, brain, and behavior. vol 9. issue 1. 2010-05-04. PMID:19817874.' |
acute and chronic stress has been suggested to inhibit hippocampal brain-derived neurotrophic factor (bdnf) synthesis and to mediate neural plasticity in response to adverse social experiences. |
2010-05-04 |
2023-08-12 |
Not clear |
| J Umka, S Mustafa, M ElBeltagy, A Thorpe, L Latif, G Bennett, P M Wigmor. Valproic acid reduces spatial working memory and cell proliferation in the hippocampus. Neuroscience. vol 166. issue 1. 2010-05-04. PMID:20006675. |
in addition, drug treatment caused a significant reduction in brain-derived neurotrophic factor (bdnf) and notch 1 but not doublecortin levels within the hippocampus. |
2010-05-04 |
2023-08-12 |
rat |
| Scott E Counts, Elliott J Mufso. Noradrenaline activation of neurotrophic pathways protects against neuronal amyloid toxicity. Journal of neurochemistry. vol 113. issue 3. 2010-05-04. PMID:20132474. |
treatment with functional blocking antibodies for either ngf or bdnf blocked na's protective actions against abeta(1-42) and abeta(25-35) toxicity in primary hippocampal and hnt neurons, respectively. |
2010-05-04 |
2023-08-12 |
human |
| Alan M Roloff, Garret R Anderson, Kirill A Martemyanov, Stanley A Thaye. Homer 1a gates the induction mechanism for endocannabinoid-mediated synaptic plasticity. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 8. 2010-05-04. PMID:20181604. |
treating hippocampal cultures with bdnf increased transcription of h1a and uncoupled homer 1c-gfp (green fluorescent protein) clusters. |
2010-05-04 |
2023-08-12 |
Not clear |
| Giuseppina Giusi, Rosa Maria Facciolo, Maria Rende, Raffaella Alò, Anna Di Vito, Simona Salerno, Sabrina Morelli, Loredana De Bartolo, Enrico Drioli, Marcello Canonac. Distinct alpha subunits of the GABAA receptor are responsible for early hippocampal silent neuron-related activities. Hippocampus. vol 19. issue 11. 2010-04-27. PMID:19338020. |
in this study, growth of hamster hippocampal neurons on biohybrid membrane substrates allowed us to show for the first time that the two major gaba(a) alpha receptor subunits (alpha(2,5)) are capable of early neuronal shaping plus expression differences of some of the main neuronal cytoskeletal factors (gap-43, the neurotrophin--bdnf) and of gluergic subtypes. |
2010-04-27 |
2023-08-12 |
Not clear |
| T V Zanelati, C Biojone, F A Moreira, F S Guimarães, Sâmia R L Joc. Antidepressant-like effects of cannabidiol in mice: possible involvement of 5-HT1A receptors. British journal of pharmacology. vol 159. issue 1. 2010-04-23. PMID:20002102. |
we also investigated if these responses depended on the activation of 5-ht(1a) receptors and on hippocampal expression of brain-derived neurotrophic factor (bdnf). |
2010-04-23 |
2023-08-12 |
mouse |
| Roberta M Cysneiros, Danuza Ferrari, Ricardo M Arida, Vera C Terra, Antonio-Carlos G de Almeida, Esper A Cavalheiro, Fulvio A Scorz. Qualitative analysis of hippocampal plastic changes in rats with epilepsy supplemented with oral omega-3 fatty acids. Epilepsy & behavior : E&B. vol 17. issue 1. 2010-04-16. PMID:19969506. |
enhanced hippocampal neurogenesis and bdnf levels and preservation of interneurons expressing parvalbumin were observed. |
2010-04-16 |
2023-08-12 |
rat |
| Joanna L Spencer, Elizabeth M Waters, Teresa A Milner, Francis S Lee, Bruce S McEwe. BDNF variant Val66Met interacts with estrous cycle in the control of hippocampal function. Proceedings of the National Academy of Sciences of the United States of America. vol 107. issue 9. 2010-04-16. PMID:20142488. |
bdnf variant val66met interacts with estrous cycle in the control of hippocampal function. |
2010-04-16 |
2023-08-12 |
mouse |
| Joanna L Spencer, Elizabeth M Waters, Teresa A Milner, Francis S Lee, Bruce S McEwe. BDNF variant Val66Met interacts with estrous cycle in the control of hippocampal function. Proceedings of the National Academy of Sciences of the United States of America. vol 107. issue 9. 2010-04-16. PMID:20142488. |
we tested whether the common human variant bdnf val66met interacts with estradiol in the control of hippocampal function in cycling female mice homozygous for the wild-type val or bdnf met variant. |
2010-04-16 |
2023-08-12 |
mouse |
| Joanna L Spencer, Elizabeth M Waters, Teresa A Milner, Francis S Lee, Bruce S McEwe. BDNF variant Val66Met interacts with estrous cycle in the control of hippocampal function. Proceedings of the National Academy of Sciences of the United States of America. vol 107. issue 9. 2010-04-16. PMID:20142488. |
bdnf met also dramatically altered the fluctuation of spatial memory, hippocampal akt phosphorylation, and psd-95 protein expression across the estrous cycle. |
2010-04-16 |
2023-08-12 |
mouse |
| Veronika G Dmitrieva, Oksana V Povarova, Veronika I Skvortsova, Svetlana A Limborska, Nikolai F Myasoedov, Lyudmila V Dergunov. Semax and Pro-Gly-Pro activate the transcription of neurotrophins and their receptor genes after cerebral ischemia. Cellular and molecular neurobiology. vol 30. issue 1. 2010-04-13. PMID:19633950. |
previous experiments showed rapid induction of bdnf, ngf, and trkb expression in intact rat hippocampus following semax treatment. |
2010-04-13 |
2023-08-12 |
rat |
| Antonio Cerasa, Enrico Tongiorgi, Francesco Fera, Maria C Gioia, Paola Valentino, Maria Liguori, Ida Manna, Giancarlo Zito, Luca Passamonti, Rita Nisticò, Aldo Quattron. The effects of BDNF Val66Met polymorphism on brain function in controls and patients with multiple sclerosis: an imaging genetic study. Behavioural brain research. vol 207. issue 2. 2010-04-13. PMID:19874854. |
a growing body of evidence demonstrates that a functional variant of the brain-derived neurotrophic factor (bdnf) gene, the val(66)met polymorphism, contributes to poor hippocampal and prefrontal functions, particularly memory processes, in healthy controls. |
2010-04-13 |
2023-08-12 |
human |
| Tin-Tin Win-Shwe, Shinji Tsukahara, Shoji Yamamoto, Atsushi Fukushima, Naoki Kunugita, Keiichi Arashidani, Hidekazu Fujimak. Up-regulation of neurotrophin-related gene expression in mouse hippocampus following low-level toluene exposure. Neurotoxicology. vol 31. issue 1. 2010-04-13. PMID:19932712. |
the expression of nerve growth factor (ngf), brain-derived neurotrophic factor (bdnf), tyrosine kinase (trk) a, and trkb mrnas in the c3h/hen mice hippocampus was significantly higher in the mice exposed to 500 ppm toluene. |
2010-04-13 |
2023-08-12 |
mouse |
| Yohei Koshimizu, Michiko Ohtom. Regulation of neurite extension by expression of LECT2 and neurotrophins based on findings in LECT2-knockout mice. Brain research. vol 1311. 2010-04-08. PMID:19917270. |
to elucidate these functions, we investigated the influence of a deficiency of lect2 on the morphology of cultured hippocampal neurons during neuronal development, and examined the expression of neurotrophins (ngf, bdnf, and nt-3) and their receptors (trka, trkb, trkc, and p75ntr) in these neurons. |
2010-04-08 |
2023-08-12 |
mouse |
| BingJin Li, Yosefu Arime, F Scott Hall, George R Uhl, Ichiro Sor. Impaired spatial working memory and decreased frontal cortex BDNF protein level in dopamine transporter knockout mice. European journal of pharmacology. vol 628. issue 1-3. 2010-04-05. PMID:19932884. |
bdnf protein was significantly decreased in frontal cortex, though not in striatum or hippocampus, of the dat ko mice. |
2010-04-05 |
2023-08-12 |
mouse |
| Li Sui, Wen-Wen Ren, Bao-Ming L. Administration of thyroid hormone increases reelin and brain-derived neurotrophic factor expression in rat hippocampus in vivo. Brain research. vol 1313. 2010-04-05. PMID:20018181. |
real time rt-pcr results revealed that t3 administration lead to a significant increase in reelin, total bdnf and exon-specific bdnf mrna expression in the hippocampus. |
2010-04-05 |
2023-08-12 |
rat |
| Li Sui, Wen-Wen Ren, Bao-Ming L. Administration of thyroid hormone increases reelin and brain-derived neurotrophic factor expression in rat hippocampus in vivo. Brain research. vol 1313. 2010-04-05. PMID:20018181. |
furthermore, the association of transcriptional coactivators (including steroid receptor coactivator-1 (src-1), camp response element binding protein-binding protein (cbp), and thyroid hormone receptor associated protein 220 (trap 220)) and rna polymerase ii (rna pol ii), with reelin and bdnf genes in the rat hippocampus displayed a distinct process following thyroid hormone administration. |
2010-04-05 |
2023-08-12 |
rat |
| Li Sui, Wen-Wen Ren, Bao-Ming L. Administration of thyroid hormone increases reelin and brain-derived neurotrophic factor expression in rat hippocampus in vivo. Brain research. vol 1313. 2010-04-05. PMID:20018181. |
these findings suggest that association of transcriptional coactivators and rna pol ii with gene promoters may be a possible mechanism explaining t3-induced reelin and bdnf expression in the hippocampus of young adult rats. |
2010-04-05 |
2023-08-12 |
rat |
| Anastasia Shulga, Anne Blaesse, Kai Kysenius, Henri J Huttunen, Kimmo Tanhuanpää, Mart Saarma, Claudio River. Thyroxin regulates BDNF expression to promote survival of injured neurons. Molecular and cellular neurosciences. vol 42. issue 4. 2010-03-30. PMID:19765661. |
here we show in organotypic hippocampal slices that thyroxin, the thyroid hormone essential for normal cns development, induces up-regulation of bdnf upon injury. |
2010-03-30 |
2023-08-12 |
Not clear |
| Wei Zheng, Osamu Honmou, Kei Miyata, Kuniaki Harada, Junpei Suzuki, He Liu, Kiyohiro Houkin, Hirofumi Hamada, Jeffery D Kocsi. Therapeutic benefits of human mesenchymal stem cells derived from bone marrow after global cerebral ischemia. Brain research. vol 1310. 2010-03-30. PMID:19913518. |
enzyme-linked immunosorbent assay (elisa) of the hippocampus revealed an increase in bdnf in hmsc-treated group. |
2010-03-30 |
2023-08-12 |
human |