| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J Cole, D R Weinberger, V S Mattay, X Cheng, A W Toga, P M Thompson, G Powell-Smith, S Cohen-Woods, A Simmons, P McGuffin, C H Y F. No effect of 5HTTLPR or BDNF Val66Met polymorphism on hippocampal morphology in major depression. Genes, brain, and behavior. vol 10. issue 7. 2012-02-22. PMID:21692988. |
no effect of 5httlpr or bdnf val66met polymorphism on hippocampal morphology in major depression. |
2012-02-22 |
2023-08-12 |
Not clear |
| J Cole, D R Weinberger, V S Mattay, X Cheng, A W Toga, P M Thompson, G Powell-Smith, S Cohen-Woods, A Simmons, P McGuffin, C H Y F. No effect of 5HTTLPR or BDNF Val66Met polymorphism on hippocampal morphology in major depression. Genes, brain, and behavior. vol 10. issue 7. 2012-02-22. PMID:21692988. |
imaging genetics studies have investigated the influence of the serotonin transporter-linked polymorphic region (5httlpr) and brain-derived neurotrophic factor (bdnf) val66met polymorphism on the hippocampus in healthy individuals and patients with depression (mdd). |
2012-02-22 |
2023-08-12 |
Not clear |
| J Cole, D R Weinberger, V S Mattay, X Cheng, A W Toga, P M Thompson, G Powell-Smith, S Cohen-Woods, A Simmons, P McGuffin, C H Y F. No effect of 5HTTLPR or BDNF Val66Met polymorphism on hippocampal morphology in major depression. Genes, brain, and behavior. vol 10. issue 7. 2012-02-22. PMID:21692988. |
however, conflicting results have led to inconclusive evidence about the effect of 5httlpr or bdnf on hippocampal volume (hcv). |
2012-02-22 |
2023-08-12 |
Not clear |
| J Cole, D R Weinberger, V S Mattay, X Cheng, A W Toga, P M Thompson, G Powell-Smith, S Cohen-Woods, A Simmons, P McGuffin, C H Y F. No effect of 5HTTLPR or BDNF Val66Met polymorphism on hippocampal morphology in major depression. Genes, brain, and behavior. vol 10. issue 7. 2012-02-22. PMID:21692988. |
manual hippocampal segmentation was conducted and the resulting data used to investigate the influence of 5httlpr and bdnf val66met genotypes on hcv and 3d shape within each sample. |
2012-02-22 |
2023-08-12 |
Not clear |
| J Cole, D R Weinberger, V S Mattay, X Cheng, A W Toga, P M Thompson, G Powell-Smith, S Cohen-Woods, A Simmons, P McGuffin, C H Y F. No effect of 5HTTLPR or BDNF Val66Met polymorphism on hippocampal morphology in major depression. Genes, brain, and behavior. vol 10. issue 7. 2012-02-22. PMID:21692988. |
hippocampal volume normalized by intracranial volume (icv) showed no significant difference between 5httlpr s allele carriers and l/l homozygotes or between bdnf met allele carriers and val/val homozygotes in the group of healthy individuals. |
2012-02-22 |
2023-08-12 |
Not clear |
| J Cole, D R Weinberger, V S Mattay, X Cheng, A W Toga, P M Thompson, G Powell-Smith, S Cohen-Woods, A Simmons, P McGuffin, C H Y F. No effect of 5HTTLPR or BDNF Val66Met polymorphism on hippocampal morphology in major depression. Genes, brain, and behavior. vol 10. issue 7. 2012-02-22. PMID:21692988. |
in this study, there was no evidence of a genetic effect for 5httlpr or bdnf val66met on hippocampal morphology in either healthy individuals or mdd patients despite the relatively large sample sizes and sensitive methodology. |
2012-02-22 |
2023-08-12 |
Not clear |
| Hossein Miladi-Gorji, Ali Rashidy-Pour, Yaghoub Fathollahi, Maziar M Akhavan, Saeed Semnanian, Manouchehr Safar. Voluntary exercise ameliorates cognitive deficits in morphine dependent rats: the role of hippocampal brain-derived neurotrophic factor. Neurobiology of learning and memory. vol 96. issue 3. 2012-02-22. PMID:21872672. |
if an effect of exercise was observed, we aimed to investigate the possible role of hippocampal brain-derived neurotrophic factor (bdnf) in the exercise-induced enhancement of learning and memory in morphine-dependent rats. |
2012-02-22 |
2023-08-12 |
rat |
| Hossein Miladi-Gorji, Ali Rashidy-Pour, Yaghoub Fathollahi, Maziar M Akhavan, Saeed Semnanian, Manouchehr Safar. Voluntary exercise ameliorates cognitive deficits in morphine dependent rats: the role of hippocampal brain-derived neurotrophic factor. Neurobiology of learning and memory. vol 96. issue 3. 2012-02-22. PMID:21872672. |
a specific bdnf inhibitor (trkb-igg chimera) was used to block the hippocampal bdnf action during the 10 days of voluntary exercise. |
2012-02-22 |
2023-08-12 |
rat |
| Kazuhiko Namekata, Chikako Harada, Xiaoli Guo, Atsuko Kimura, Daiji Kittaka, Hayaki Watanabe, Takayuki Harad. Dock3 stimulates axonal outgrowth via GSK-3β-mediated microtubule assembly. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 1. 2012-02-22. PMID:22219288. |
exogenously applied bdnf induced the phosphorylation of gsk-3β and dephosphorylation of crmp-2 in hippocampal neurons. |
2012-02-22 |
2023-08-12 |
mouse |
| Alexandra Heyden, Mihai-Constantin S Ionescu, Stefano Romorini, Bettina Kracht, Veronica Ghiglieri, Paolo Calabresi, Constanze Seidenbecher, Frank Angenstein, Eckart D Gundelfinge. Hippocampal enlargement in Bassoon-mutant mice is associated with enhanced neurogenesis, reduced apoptosis, and abnormal BDNF levels. Cell and tissue research. vol 346. issue 1. 2012-02-21. PMID:21935677. |
hippocampal enlargement in bassoon-mutant mice is associated with enhanced neurogenesis, reduced apoptosis, and abnormal bdnf levels. |
2012-02-21 |
2023-08-12 |
mouse |
| Alexandra Heyden, Mihai-Constantin S Ionescu, Stefano Romorini, Bettina Kracht, Veronica Ghiglieri, Paolo Calabresi, Constanze Seidenbecher, Frank Angenstein, Eckart D Gundelfinge. Hippocampal enlargement in Bassoon-mutant mice is associated with enhanced neurogenesis, reduced apoptosis, and abnormal BDNF levels. Cell and tissue research. vol 346. issue 1. 2012-02-21. PMID:21935677. |
enlargement of the hippocampus and of other forebrain structures was accompanied by increased levels of brain-derived neurotrophic factor (bdnf). |
2012-02-21 |
2023-08-12 |
mouse |
| Alexandra Heyden, Mihai-Constantin S Ionescu, Stefano Romorini, Bettina Kracht, Veronica Ghiglieri, Paolo Calabresi, Constanze Seidenbecher, Frank Angenstein, Eckart D Gundelfinge. Hippocampal enlargement in Bassoon-mutant mice is associated with enhanced neurogenesis, reduced apoptosis, and abnormal BDNF levels. Cell and tissue research. vol 346. issue 1. 2012-02-21. PMID:21935677. |
these data show that hippocampal overgrowth in bassoon-mutant mice arises from a dysregulation of neurogenesis and apoptosis that might be associated with unbalanced bdnf levels. |
2012-02-21 |
2023-08-12 |
mouse |
| Sheketha R Hauser, Bruk Getachew, Robert E Taylor, Yousef Tizab. Alcohol induced depressive-like behavior is associated with a reduction in hippocampal BDNF. Pharmacology, biochemistry, and behavior. vol 100. issue 2. 2012-02-16. PMID:21930150. |
alcohol induced depressive-like behavior is associated with a reduction in hippocampal bdnf. |
2012-02-16 |
2023-08-12 |
rat |
| Sheketha R Hauser, Bruk Getachew, Robert E Taylor, Yousef Tizab. Alcohol induced depressive-like behavior is associated with a reduction in hippocampal BDNF. Pharmacology, biochemistry, and behavior. vol 100. issue 2. 2012-02-16. PMID:21930150. |
since brain derived neurotrophic factor (bdnf) is considered to play an important role in depressive-like behaviors and its elevation, particularly in the hippocampus, appears to be critical for the action of many antidepressants, we hypothesized that: 1. |
2012-02-16 |
2023-08-12 |
rat |
| Sheketha R Hauser, Bruk Getachew, Robert E Taylor, Yousef Tizab. Alcohol induced depressive-like behavior is associated with a reduction in hippocampal BDNF. Pharmacology, biochemistry, and behavior. vol 100. issue 2. 2012-02-16. PMID:21930150. |
wky rats, a putative animal model of depression, will show a lower hippocampal bdnf compared to their control wistar rats, 2. |
2012-02-16 |
2023-08-12 |
rat |
| Sheketha R Hauser, Bruk Getachew, Robert E Taylor, Yousef Tizab. Alcohol induced depressive-like behavior is associated with a reduction in hippocampal BDNF. Pharmacology, biochemistry, and behavior. vol 100. issue 2. 2012-02-16. PMID:21930150. |
alcohol-induced depressive like behavior will be associated with a significant decrease in hippocampal bdnf and 3. |
2012-02-16 |
2023-08-12 |
rat |
| Sheketha R Hauser, Bruk Getachew, Robert E Taylor, Yousef Tizab. Alcohol induced depressive-like behavior is associated with a reduction in hippocampal BDNF. Pharmacology, biochemistry, and behavior. vol 100. issue 2. 2012-02-16. PMID:21930150. |
treatments with antidepressants will normalize hippocampal bdnf. |
2012-02-16 |
2023-08-12 |
rat |
| Sheketha R Hauser, Bruk Getachew, Robert E Taylor, Yousef Tizab. Alcohol induced depressive-like behavior is associated with a reduction in hippocampal BDNF. Pharmacology, biochemistry, and behavior. vol 100. issue 2. 2012-02-16. PMID:21930150. |
these postulates were verified by measuring hippocampal bdnf in wistar and wky rats at baseline, following chronic (10 day) treatment with alcohol and combination of alcohol with nomifensine or imipramine. |
2012-02-16 |
2023-08-12 |
rat |
| Sheketha R Hauser, Bruk Getachew, Robert E Taylor, Yousef Tizab. Alcohol induced depressive-like behavior is associated with a reduction in hippocampal BDNF. Pharmacology, biochemistry, and behavior. vol 100. issue 2. 2012-02-16. PMID:21930150. |
moreover, depression per se as manifested in wky rats may be associated with a reduction in hippocampal bdnf. |
2012-02-16 |
2023-08-12 |
rat |
| Hong Kim, Hong-Im Heo, Dong-Hyun Kim, Il-Gyu Ko, Su-Shin Lee, Sung-Eun Kim, Bo-Kyun Kim, Tae-Woon Kim, Eun-Sang Ji, Jae-Deung Kim, Mal-Soon Shin, Young-Woong Choi, Chang-Ju Ki. Treadmill exercise and methylphenidate ameliorate symptoms of attention deficit/hyperactivity disorder through enhancing dopamine synthesis and brain-derived neurotrophic factor expression in spontaneous hypertensive rats. Neuroscience letters. vol 504. issue 1. 2012-02-14. PMID:21907264. |
reduction of th in the striatum and substantia nigra and bdnf in the hippocampus was observed of the rats in the adhd group. |
2012-02-14 |
2023-08-12 |
rat |