| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| He Xu, Hui-Ling Gao, Wei Zheng, Na Xin, Zhi-Hong Chi, Shu-Ling Bai, Zhan-You Wan. Lactational zinc deficiency-induced hippocampal neuronal apoptosis by a BDNF-independent TrkB signaling pathway. Hippocampus. vol 21. issue 5. 2012-03-26. PMID:20101602. |
most interestingly, our data showed that the activity of src, a key molecule for zinc-induced trkb activation through the bdnf-independent pathway, was inhibited significantly, and the expression levels of bdnf were significantly increased in the hippocampus of suckling mice. |
2012-03-26 |
2023-08-12 |
mouse |
| He Xu, Hui-Ling Gao, Wei Zheng, Na Xin, Zhi-Hong Chi, Shu-Ling Bai, Zhan-You Wan. Lactational zinc deficiency-induced hippocampal neuronal apoptosis by a BDNF-independent TrkB signaling pathway. Hippocampus. vol 21. issue 5. 2012-03-26. PMID:20101602. |
the present data indicate that zinc depletion-induced hippocampal neuronal apoptosis is likely through modulation of the trkb neurotrophic signaling pathway by a bdnf-independent and src-dependent mechanism, whereas higher expression of bdnf is considered as a protective response, which cannot fully compensate for the injury caused by maternal zinc deficiency. |
2012-03-26 |
2023-08-12 |
mouse |
| Andréa G K Ferreira, Emilene B Scherer, Maira J da Cunha, Fernanda R Machado, Aline A da Cunha, Jeferson S Graeff, Carlos A Netto, Angela T S Wys. Physical exercise reverses cognitive impairment in rats subjected to experimental hyperprolinemia. Neurochemical research. vol 36. issue 12. 2012-03-12. PMID:21792675. |
results show that proline impairs cognitive performance, decreases bdnf in cerebral cortex and hippocampus and increases ache activity in hippocampus. |
2012-03-12 |
2023-08-12 |
rat |
| Bárbara Tagliari, Emilene B Scherer, Fernanda R Machado, Andréa G K Ferreira, Carla Dalmaz, Angela T S Wys. Antioxidants prevent memory deficits provoked by chronic variable stress in rats. Neurochemical research. vol 36. issue 12. 2012-03-12. PMID:21822921. |
brain-derived neurotrophic factor (bdnf) immunocontent was also evaluated in hippocampus of rats. |
2012-03-12 |
2023-08-12 |
rat |
| Bárbara Tagliari, Emilene B Scherer, Fernanda R Machado, Andréa G K Ferreira, Carla Dalmaz, Angela T S Wys. Antioxidants prevent memory deficits provoked by chronic variable stress in rats. Neurochemical research. vol 36. issue 12. 2012-03-12. PMID:21822921. |
the bdnf levels were not altered in hippocampus of stressed group when compared to controls. |
2012-03-12 |
2023-08-12 |
rat |
| De-Qiang Li, Xu-Juan Li, Jin-Feng Duan, Wei Ca. Wuling Capsule promotes hippocampal neurogenesis by improving expression of connexin 43 in rats exposed to chronic unpredictable mild stress. Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine. vol 8. issue 7. 2012-03-06. PMID:20619143. |
to investigate the effects of wuling capsule, a compound traditional chinese herbal medicine, on hippocampal neurogenesis by examining the expressions of brain-derived neurotrophic factor (bdnf) and connexin 43 (cx43) in rats with depression induced by chronic unpredictable mild stress (cms), and thereby to explore its antidepressant mechanism. |
2012-03-06 |
2023-08-12 |
rat |
| W Ito, M Chehab, S Thakur, J Li, A Morozo. BDNF-restricted knockout mice as an animal model for aggression. Genes, brain, and behavior. vol 10. issue 3. 2012-03-06. PMID:21255268. |
here we performed behavioral characterization of conditional bdnf knockout mice generated using a cre recombinase driver line, ka1-cre, which expresses cre in few areas of brain: highly at hippocampal area ca3 and moderately in dentate gyrus, cerebellum and facial nerve nucleus. |
2012-03-06 |
2023-08-12 |
mouse |
| Sung Woo Park, Vu Thi Phuong, Chan Hong Lee, Jung Goo Lee, Mi Kyoung Seo, Hye Yeon Cho, Zheng Huan Fang, Bong Ju Lee, Young Hoon Ki. Effects of antipsychotic drugs on BDNF, GSK-3β, and β-catenin expression in rats subjected to immobilization stress. Neuroscience research. vol 71. issue 4. 2012-03-05. PMID:21893111. |
in this study, we analyzed the effects of the atypical antipsychotic drugs olanzapine and aripiprazole and a typical antipsychotic drug, haloperidol, on the expression of bdnf, phosphorylated gsk-3β, and β-catenin in the hippocampus of rats subjected to immobilization stress. |
2012-03-05 |
2023-08-12 |
rat |
| Sung Woo Park, Vu Thi Phuong, Chan Hong Lee, Jung Goo Lee, Mi Kyoung Seo, Hye Yeon Cho, Zheng Huan Fang, Bong Ju Lee, Young Hoon Ki. Effects of antipsychotic drugs on BDNF, GSK-3β, and β-catenin expression in rats subjected to immobilization stress. Neuroscience research. vol 71. issue 4. 2012-03-05. PMID:21893111. |
immobilization stress significantly decreased the expression of bdnf, phosphorylated gsk-3β, and β-catenin in the hippocampus. |
2012-03-05 |
2023-08-12 |
rat |
| Nicole Ruiz, Luis F Pacheco, Bianca Farrell, Cody B Cox, Boris S Ermolinsky, Emilio R Garrido-Sanabria, Saraswathy Nai. Metabolic gene expression changes in the hippocampus of obese epileptic male rats in the pilocarpine model of temporal lobe epilepsy. Brain research. vol 1426. 2012-03-05. PMID:22050960. |
we determined the expression levels of genes hsd11b1, nr3c1, abcc8, kcnj11, mc4r, npy, lepr, bdnf, and drd2 that are involved in regulation of energy metabolism, in the hippocampus of age-matched control and chronic epileptic animals. |
2012-03-05 |
2023-08-12 |
rat |
| Valeria Mondelli, Annamaria Cattaneo, Martino Belvederi Murri, Marta Di Forti, Rowena Handley, Nilay Hepgul, Ana Miorelli, Serena Navari, Andrew S Papadopoulos, Katherine J Aitchison, Craig Morgan, Robin M Murray, Paola Dazzan, Carmine M Pariant. Stress and inflammation reduce brain-derived neurotrophic factor expression in first-episode psychosis: a pathway to smaller hippocampal volume. The Journal of clinical psychiatry. vol 72. issue 12. 2012-03-02. PMID:21672499. |
the aim of this cross-sectional case-control study was to investigate potential causes and consequences of reduced bdnf expression in these patients by examining the association between bdnf levels and measures of stress, inflammation, and hippocampal volume in first-episode psychosis. |
2012-03-02 |
2023-08-12 |
Not clear |
| Ahmad A Khundakar, Tyra S C Zetterströ. Effects of GABAB ligands alone and in combination with paroxetine on hippocampal BDNF gene expression. European journal of pharmacology. vol 671. issue 1-3. 2012-03-01. PMID:21930121. |
effects of gabab ligands alone and in combination with paroxetine on hippocampal bdnf gene expression. |
2012-03-01 |
2023-08-12 |
rat |
| Ahmad A Khundakar, Tyra S C Zetterströ. Effects of GABAB ligands alone and in combination with paroxetine on hippocampal BDNF gene expression. European journal of pharmacology. vol 671. issue 1-3. 2012-03-01. PMID:21930121. |
brain-derived neurotrophic factor (bdnf) has been suggested as a target for antidepressant treatment and chronic antidepressant drug administration shows a 'biphasic effect' on bdnf mrna in rat hippocampus (transient decrease followed by an increase). |
2012-03-01 |
2023-08-12 |
rat |
| Ahmad A Khundakar, Tyra S C Zetterströ. Effects of GABAB ligands alone and in combination with paroxetine on hippocampal BDNF gene expression. European journal of pharmacology. vol 671. issue 1-3. 2012-03-01. PMID:21930121. |
), administration resulted in significant inhibition of bdnf mrna expression in the cornu ammonis 3 and dentate gyrus but not in the cornu ammonis 1 region of the hippocampus. |
2012-03-01 |
2023-08-12 |
rat |
| Ahmad A Khundakar, Tyra S C Zetterströ. Effects of GABAB ligands alone and in combination with paroxetine on hippocampal BDNF gene expression. European journal of pharmacology. vol 671. issue 1-3. 2012-03-01. PMID:21930121. |
the inhibitory effect of baclofen on hippocampal bdnf mrna expression was significantly attenuated by pre-treatment the selective gaba(b) antagonists, cgp 46381 and cgp 55845 (10mg/kg, i.p.). |
2012-03-01 |
2023-08-12 |
rat |
| Ahmad A Khundakar, Tyra S C Zetterströ. Effects of GABAB ligands alone and in combination with paroxetine on hippocampal BDNF gene expression. European journal of pharmacology. vol 671. issue 1-3. 2012-03-01. PMID:21930121. |
the inhibitory action by the selective serotonin re-uptake inhibitor (ssri) paroxetine on hippocampal bdnf mrna was also attenuated by cgp 46381. |
2012-03-01 |
2023-08-12 |
rat |
| Ahmad A Khundakar, Tyra S C Zetterströ. Effects of GABAB ligands alone and in combination with paroxetine on hippocampal BDNF gene expression. European journal of pharmacology. vol 671. issue 1-3. 2012-03-01. PMID:21930121. |
our findings suggest a role for gaba(b), but not gaba(a), receptor-mediated mechanisms in the inhibitory regulation of basal hippocampal bdnf gene expression. |
2012-03-01 |
2023-08-12 |
rat |
| Ahmad A Khundakar, Tyra S C Zetterströ. Effects of GABAB ligands alone and in combination with paroxetine on hippocampal BDNF gene expression. European journal of pharmacology. vol 671. issue 1-3. 2012-03-01. PMID:21930121. |
our results indicate that gaba(b) receptor activation may play a role in the antidepressant drug-induced inhibition of bdnf gene expression in the hippocampus. |
2012-03-01 |
2023-08-12 |
rat |
| Suk-Yu Yau, Benson Wui-Man Lau, Jian-Bin Tong, Richard Wong, Yick-Pang Ching, Guang Qiu, Siu-Wa Tang, Tatia M C Lee, Kwok-Fai S. Hippocampal neurogenesis and dendritic plasticity support running-improved spatial learning and depression-like behaviour in stressed rats. PloS one. vol 6. issue 9. 2012-02-28. PMID:21935393. |
repeated cort treatment resulted in a graded increase in depression-like behaviour and impaired spatial learning that is associated with decreased hippocampal cell proliferation and bdnf levels. |
2012-02-28 |
2023-08-12 |
rat |
| Y Pan, L Chau, S Liu, M V Avshalumov, M E Rice, K D Car. A food restriction protocol that increases drug reward decreases tropomyosin receptor kinase B in the ventral tegmental area, with no effect on brain-derived neurotrophic factor or tropomyosin receptor kinase B protein levels in dopaminergic forebrain regions. Neuroscience. vol 197. 2012-02-27. PMID:21945647. |
food restriction (fr) decreases brain-derived neurotrophic factor (bdnf) expression in hypothalamic and hindbrain regions that regulate feeding and metabolic efficiency, while increasing expression in hippocampal and neocortical regions. |
2012-02-27 |
2023-08-12 |
human |