| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Timothy R Chapman, Ruth M Barrientos, Jared T Ahrendsen, Jennifer M Hoover, Steven F Maier, Susan L Patterso. Aging and infection reduce expression of specific brain-derived neurotrophic factor mRNAs in hippocampus. Neurobiology of aging. vol 33. issue 4. 2012-06-15. PMID:21907460. |
here we have investigated the effects of age and infection on basal and fear-conditioning-stimulated expression of bdnf in hippocampus. |
2012-06-15 |
2023-08-12 |
rat |
| Camin Dean, Huisheng Liu, Thorsten Staudt, Markus A Stahlberg, Siv Vingill, Johanna Bückers, Dirk Kamin, Johann Engelhardt, Meyer B Jackson, Stefan W Hell, Edwin R Chapma. Distinct subsets of Syt-IV/BDNF vesicles are sorted to axons versus dendrites and recruited to synapses by activity. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 16. 2012-06-12. PMID:22514304. |
here, using photoactivation of bdnf or syt-iv (a regulator of exocytosis present on bdnf-containing vesicles) in transfected rat hippocampal neurons, we discovered that distinct subsets of bdnf vesicles are targeted to axons versus dendrites and are not shared between these compartments. |
2012-06-12 |
2023-08-12 |
mouse |
| Darcy Litteljohn, Eric Nelson, Cheri Bethune, Shawn Hayle. The effects of paraquat on regional brain neurotransmitter activity, hippocampal BDNF and behavioural function in female mice. Neuroscience letters. vol 502. issue 3. 2012-06-11. PMID:21835224. |
the effects of paraquat on regional brain neurotransmitter activity, hippocampal bdnf and behavioural function in female mice. |
2012-06-11 |
2023-08-12 |
mouse |
| Darcy Litteljohn, Eric Nelson, Cheri Bethune, Shawn Hayle. The effects of paraquat on regional brain neurotransmitter activity, hippocampal BDNF and behavioural function in female mice. Neuroscience letters. vol 502. issue 3. 2012-06-11. PMID:21835224. |
the augmented hippocampal bdnf and noradrenergic changes observed could conceivably act to buffer female mice against some of the deleterious behavioural effects of parquat. |
2012-06-11 |
2023-08-12 |
mouse |
| Harini Lakshminarasimhan, Sumantra Chattarj. Stress leads to contrasting effects on the levels of brain derived neurotrophic factor in the hippocampus and amygdala. PloS one. vol 7. issue 1. 2012-06-11. PMID:22272355. |
because bdnf is known to be a key regulator of dendritic architecture and spines, we investigated if the levels of bdnf expression reflect the divergent effects of stress on the hippocampus and amygdala. |
2012-06-11 |
2023-08-12 |
rat |
| Harini Lakshminarasimhan, Sumantra Chattarj. Stress leads to contrasting effects on the levels of brain derived neurotrophic factor in the hippocampus and amygdala. PloS one. vol 7. issue 1. 2012-06-11. PMID:22272355. |
these results point to a role for bdnf in stress-induced structural plasticity across both hippocampus and amygdala, two brain areas that have also been implicated in the cognitive and affective symptoms of stress-related psychiatric disorders. |
2012-06-11 |
2023-08-12 |
rat |
| Geoffrey N Smith, Allen E Thornton, Donna J Lang, G William Macewan, Thomas S Ehmann, Lili C Kopala, Karen Tee, Gillian Shiau, Aristotle N Voineskos, James L Kennedy, William G Hone. Hippocampal volume and the brain-derived neurotrophic factor Val66Met polymorphism in first episode psychosis. Schizophrenia research. vol 134. issue 2-3. 2012-06-04. PMID:22192502. |
small hippocampi and impaired memory are common in patients with psychosis and brain-derived neurotrophic factor (bdnf) plays a critical role in hippocampal neuroplasticity and memory. |
2012-06-04 |
2023-08-12 |
Not clear |
| Oliver Gruber, Alkomiet Hasan, Harald Scherk, Thomas Wobrock, Thomas Schneider-Axmann, Savira Ekawardhani, Andrea Schmitt, Martin Backens, Wolfgang Reith, Jobst Meyer, Peter Falka. Association of the brain-derived neurotrophic factor val66met polymorphism with magnetic resonance spectroscopic markers in the human hippocampus: in vivo evidence for effects on the glutamate system. European archives of psychiatry and clinical neuroscience. vol 262. issue 1. 2012-05-31. PMID:21509595. |
the brain-derived neurotrophic factor (bdnf) is a key regulator of synaptic plasticity and has been suggested to be involved in the pathophysiology and pathogenesis of psychotic disorders, with particular emphasis on dysfunctions of the hippocampus. |
2012-05-31 |
2023-08-12 |
human |
| Oliver Gruber, Alkomiet Hasan, Harald Scherk, Thomas Wobrock, Thomas Schneider-Axmann, Savira Ekawardhani, Andrea Schmitt, Martin Backens, Wolfgang Reith, Jobst Meyer, Peter Falka. Association of the brain-derived neurotrophic factor val66met polymorphism with magnetic resonance spectroscopic markers in the human hippocampus: in vivo evidence for effects on the glutamate system. European archives of psychiatry and clinical neuroscience. vol 262. issue 1. 2012-05-31. PMID:21509595. |
the aim of the present study was to replicate and to extend prior findings of bdnf val66met genotype effects on hippocampal volume and n-acetyl aspartate (naa) levels. |
2012-05-31 |
2023-08-12 |
human |
| Oliver Gruber, Alkomiet Hasan, Harald Scherk, Thomas Wobrock, Thomas Schneider-Axmann, Savira Ekawardhani, Andrea Schmitt, Martin Backens, Wolfgang Reith, Jobst Meyer, Peter Falka. Association of the brain-derived neurotrophic factor val66met polymorphism with magnetic resonance spectroscopic markers in the human hippocampus: in vivo evidence for effects on the glutamate system. European archives of psychiatry and clinical neuroscience. vol 262. issue 1. 2012-05-31. PMID:21509595. |
bdnf genotype did not impact hippocampal volumes. |
2012-05-31 |
2023-08-12 |
human |
| Oliver Gruber, Alkomiet Hasan, Harald Scherk, Thomas Wobrock, Thomas Schneider-Axmann, Savira Ekawardhani, Andrea Schmitt, Martin Backens, Wolfgang Reith, Jobst Meyer, Peter Falka. Association of the brain-derived neurotrophic factor val66met polymorphism with magnetic resonance spectroscopic markers in the human hippocampus: in vivo evidence for effects on the glutamate system. European archives of psychiatry and clinical neuroscience. vol 262. issue 1. 2012-05-31. PMID:21509595. |
these findings provide first in vivo evidence for an effect of the functional bdnf val66met polymorphism on the glutamate system in human hippocampus. |
2012-05-31 |
2023-08-12 |
human |
| Zheng Ke, Shea-Ping Yip, Le Li, Xiao-Xiang Zheng, Wing-Kin Tam, Kai-Yu Ton. The effects of voluntary, involuntary, and forced exercises on motor recovery in a stroke rat model. Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference. vol 2011. 2012-05-31. PMID:22256251. |
the results showed that voluntary exercise is the most effective intervention in upregulating the hippocampal bdnf level, and facilitating motor recovery after brain ischemia. |
2012-05-31 |
2023-08-12 |
rat |
| Ozge Oztan, Cigdem Aydin, Ceylan Isgo. Stressful environmental and social stimulation in adolescence causes antidepressant-like effects associated with epigenetic induction of the hippocampal BDNF and mossy fibre sprouting in the novelty-seeking phenotype. Neuroscience letters. vol 501. issue 2. 2012-05-29. PMID:21767606. |
stressful environmental and social stimulation in adolescence causes antidepressant-like effects associated with epigenetic induction of the hippocampal bdnf and mossy fibre sprouting in the novelty-seeking phenotype. |
2012-05-29 |
2023-08-12 |
rat |
| Ozge Oztan, Cigdem Aydin, Ceylan Isgo. Stressful environmental and social stimulation in adolescence causes antidepressant-like effects associated with epigenetic induction of the hippocampal BDNF and mossy fibre sprouting in the novelty-seeking phenotype. Neuroscience letters. vol 501. issue 2. 2012-05-29. PMID:21767606. |
the ess exposure during the peripubertal-juvenile period led to antidepressive-like effects on the forced swim test associated with increase in acetylation of histones 3 and 4 at the promoter regions p2 and p4 of the brain-derived neurotrophic factor (bdnf) gene in the dorsal hippocampus of hrs. |
2012-05-29 |
2023-08-12 |
rat |
| Ozge Oztan, Cigdem Aydin, Ceylan Isgo. Stressful environmental and social stimulation in adolescence causes antidepressant-like effects associated with epigenetic induction of the hippocampal BDNF and mossy fibre sprouting in the novelty-seeking phenotype. Neuroscience letters. vol 501. issue 2. 2012-05-29. PMID:21767606. |
moreover, epigenetic activation of the hippocampal bdnf in the hrs following ess exposure was accompanied by increase in the supra-pyramidal mossy fibre (sp-mf) and total mossy fibre terminal field volumes compared to handled controls. |
2012-05-29 |
2023-08-12 |
rat |
| Ozge Oztan, Cigdem Aydin, Ceylan Isgo. Stressful environmental and social stimulation in adolescence causes antidepressant-like effects associated with epigenetic induction of the hippocampal BDNF and mossy fibre sprouting in the novelty-seeking phenotype. Neuroscience letters. vol 501. issue 2. 2012-05-29. PMID:21767606. |
these findings suggest that the ess exposure in the peripubertal-juvenile period may constitute an example of environmental induction of the hippocampal bdnf, and may mimic behavioral effects of exogenous antidepressants in the hr phenotype. |
2012-05-29 |
2023-08-12 |
rat |
| Dinko Kranjac, Kristina A McLinden, Kyle M Koster, David L Kaldenbach, Michael J Chumley, Gary W Boeh. Peripheral administration of poly I:C disrupts contextual fear memory consolidation and BDNF expression in mice. Behavioural brain research. vol 228. issue 2. 2012-05-23. PMID:22222172. |
this memory deficit coincided with a decrease in hippocampal and cortical bdnf mrna expression. |
2012-05-23 |
2023-08-12 |
mouse |
| Kirk I Erickson, Destiny L Miller, Kathryn A Roecklei. The aging hippocampus: interactions between exercise, depression, and BDNF. The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry. vol 18. issue 1. 2012-05-18. PMID:21531985. |
the aging hippocampus: interactions between exercise, depression, and bdnf. |
2012-05-18 |
2023-08-12 |
Not clear |
| Kirk I Erickson, Destiny L Miller, Kathryn A Roecklei. The aging hippocampus: interactions between exercise, depression, and BDNF. The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry. vol 18. issue 1. 2012-05-18. PMID:21531985. |
although there are multiple paths by which hippocampal deterioration occurs in late life, the authors discuss the evidence that a single nucleotide polymorphism in the brain-derived neurotrophic factor (bdnf) gene and age-related changes in bdnf protein or receptor expression contribute to hippocampal atrophy. |
2012-05-18 |
2023-08-12 |
Not clear |
| Kirk I Erickson, Destiny L Miller, Kathryn A Roecklei. The aging hippocampus: interactions between exercise, depression, and BDNF. The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry. vol 18. issue 1. 2012-05-18. PMID:21531985. |
the authors conclude that few studies have tested whether bdnf mediates age-related hippocampal atrophy and memory impairment. |
2012-05-18 |
2023-08-12 |
Not clear |