Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Fabio Fumagalli, Francesca Calabrese, Alessia Luoni, Mohammed Shahid, Giorgio Racagni, Marco A Riv. The AMPA receptor potentiator Org 26576 modulates stress-induced transcription of BDNF isoforms in rat hippocampus. Pharmacological research. vol 65. issue 2. 2012-08-20. PMID:22079295. |
the ampa receptor potentiator org 26576 modulates stress-induced transcription of bdnf isoforms in rat hippocampus. |
2012-08-20 |
2023-08-12 |
rat |
Fabio Fumagalli, Francesca Calabrese, Alessia Luoni, Mohammed Shahid, Giorgio Racagni, Marco A Riv. The AMPA receptor potentiator Org 26576 modulates stress-induced transcription of BDNF isoforms in rat hippocampus. Pharmacological research. vol 65. issue 2. 2012-08-20. PMID:22079295. |
total bdnf mrna levels were significantly increased in the hippocampus of animals exposed to the combination of org 26576 and stress whereas, in prefrontal and frontal cortices, bdnf mrna levels were modulated by the acute stress, independently from drug treatment. |
2012-08-20 |
2023-08-12 |
rat |
Fabio Fumagalli, Francesca Calabrese, Alessia Luoni, Mohammed Shahid, Giorgio Racagni, Marco A Riv. The AMPA receptor potentiator Org 26576 modulates stress-induced transcription of BDNF isoforms in rat hippocampus. Pharmacological research. vol 65. issue 2. 2012-08-20. PMID:22079295. |
the analysis of bdnf transcripts in the hippocampus revealed a major contribution of exons i and iv. |
2012-08-20 |
2023-08-12 |
rat |
Stacie L Taylor, Lisa M Stanek, Kerry J Ressler, Kim L Huhma. Differential brain-derived neurotrophic factor expression in limbic brain regions following social defeat or territorial aggression. Behavioral neuroscience. vol 125. issue 6. 2012-08-20. PMID:22122152. |
interestingly, winning animals had significantly more bdnf mrna in the dentate gyrus of the dorsal hippocampus than did losing animals, novel, and home cage controls. |
2012-08-20 |
2023-08-12 |
Not clear |
Dae Young Yoo, Woosuk Kim, Sung Min Nam, Jin Young Chung, Jung Hoon Choi, Yeo Sung Yoon, Moo-Ho Won, In Koo Hwan. Chronic effects of pyridoxine in the gerbil hippocampal CA1 region after transient forebrain ischemia. Neurochemical research. vol 37. issue 5. 2012-08-20. PMID:22228142. |
these results suggest that chronic administration of pyridoxine enhances neuroblast differentiation in the dentate gyrus and induces new mature neurons in the hippocampal ca1 region by up-regulating bdnf expression in hippocampal homogenates. |
2012-08-20 |
2023-08-12 |
mouse |
Bombi Lee, Insop Shim, Hyejung Lee, Dae-Hyun Hah. Effect of ginsenoside Re on depression- and anxiety-like behaviors and cognition memory deficit induced by repeated immobilization in rats. Journal of microbiology and biotechnology. vol 22. issue 5. 2012-08-20. PMID:22561867. |
administration of gre also significantly blocked the increase in th expression in the locus coeruleus (lc) and the decrease in bdnf mrna expression in the hippocampus. |
2012-08-20 |
2023-08-12 |
rat |
Orestes V Forlenza, Vanessa J de Paula, Rodrigo Machado-Vieira, Breno S Diniz, Wagner F Gatta. Does lithium prevent Alzheimer's disease? Drugs & aging. vol 29. issue 5. 2012-08-15. PMID:22500970. |
in humans, lithium treatment has been associated with humoral and structural evidence of neuroprotection, such as increased expression of anti-apoptotic genes, inhibition of cellular oxidative stress, synthesis of brain-derived neurotrophic factor (bdnf), cortical thickening, increased grey matter density, and hippocampal enlargement. |
2012-08-15 |
2023-08-12 |
Not clear |
Aparecida Vines, Ana Marcia Delattre, Marcelo M S Lima, Laís Soares Rodrigues, Deborah Suchecki, Ricardo B Machado, Sergio Tufik, Sofia I R Pereira, Sílvio M Zanata, Anete Curte Ferra. The role of 5-HT₁A receptors in fish oil-mediated increased BDNF expression in the rat hippocampus and cortex: a possible antidepressant mechanism. Neuropharmacology. vol 62. issue 1. 2012-08-13. PMID:21740919. |
the role of 5-ht₁a receptors in fish oil-mediated increased bdnf expression in the rat hippocampus and cortex: a possible antidepressant mechanism. |
2012-08-13 |
2023-08-12 |
rat |
Aparecida Vines, Ana Marcia Delattre, Marcelo M S Lima, Laís Soares Rodrigues, Deborah Suchecki, Ricardo B Machado, Sergio Tufik, Sofia I R Pereira, Sílvio M Zanata, Anete Curte Ferra. The role of 5-HT₁A receptors in fish oil-mediated increased BDNF expression in the rat hippocampus and cortex: a possible antidepressant mechanism. Neuropharmacology. vol 62. issue 1. 2012-08-13. PMID:21740919. |
the present study was performed to evaluate the involvement of serotonin (5-ht) receptors, particularly of 5-ht(1a), and hippocampal brain-derived neurotrophic factor (bdnf) expression in the antidepressant effect of ω-3 pufa supplementation. |
2012-08-13 |
2023-08-12 |
rat |
Aparecida Vines, Ana Marcia Delattre, Marcelo M S Lima, Laís Soares Rodrigues, Deborah Suchecki, Ricardo B Machado, Sergio Tufik, Sofia I R Pereira, Sílvio M Zanata, Anete Curte Ferra. The role of 5-HT₁A receptors in fish oil-mediated increased BDNF expression in the rat hippocampus and cortex: a possible antidepressant mechanism. Neuropharmacology. vol 62. issue 1. 2012-08-13. PMID:21740919. |
in experiment 2, cortical and hippocampal contents of bdnf, 5-ht, dopamine (da) and its metabolites, 5-hydroxyindoleacetic acid (5-hiaa), and 3,4-dihydroxyphenylacetic acid (dopac), were determined in animals subjected to the same protocol. |
2012-08-13 |
2023-08-12 |
rat |
Aparecida Vines, Ana Marcia Delattre, Marcelo M S Lima, Laís Soares Rodrigues, Deborah Suchecki, Ricardo B Machado, Sergio Tufik, Sofia I R Pereira, Sílvio M Zanata, Anete Curte Ferra. The role of 5-HT₁A receptors in fish oil-mediated increased BDNF expression in the rat hippocampus and cortex: a possible antidepressant mechanism. Neuropharmacology. vol 62. issue 1. 2012-08-13. PMID:21740919. |
increased bdnf expression in the cortex and hippocampus of both age groups was detected. |
2012-08-13 |
2023-08-12 |
rat |
Hendrikus Hendriksen, Didier Meulendijks, Tessa N Douma, Diewertje I Bink, Megan E Breuer, Koen G C Westphal, Berend Olivier, Ronald S Oostin. Environmental enrichment has antidepressant-like action without improving learning and memory deficits in olfactory bulbectomized rats. Neuropharmacology. vol 62. issue 1. 2012-08-13. PMID:21807004. |
we quantified hippocampal mrna levels of the neurotrophic factors bdnf, vgf and vegf. |
2012-08-13 |
2023-08-12 |
rat |
Jesse S O Lindholm, Henri Autio, Liisa Vesa, Hanna Antila, Lothar Lindemann, Marius C Hoener, Phil Skolnick, Tomi Rantamäki, Eero Castré. The antidepressant-like effects of glutamatergic drugs ketamine and AMPA receptor potentiator LY 451646 are preserved in bdnf⁺/⁻ heterozygous null mice. Neuropharmacology. vol 62. issue 1. 2012-08-13. PMID:21867718. |
neither ketamine nor ly 451646 significantly influenced the levels bdnf or trkb phosphorylation in the hippocampus when assessed at 45 min or 7 days after the drug administration. |
2012-08-13 |
2023-08-12 |
mouse |
Séverine Farley, Sylvie Dumas, Salah El Mestikawy, Bruno Giro. Increased expression of the Vesicular Glutamate Transporter-1 (VGLUT1) in the prefrontal cortex correlates with differential vulnerability to chronic stress in various mouse strains: effects of fluoxetine and MK-801. Neuropharmacology. vol 62. issue 1. 2012-08-13. PMID:21945287. |
fluoxetine increased vglut1 and bdnf mrna expression in the hippocampus of the c57bl/6 but not in the balb/c strain, suggesting a different reactivity in-between strain to both stress and antidepressant. |
2012-08-13 |
2023-08-12 |
mouse |
Lou-yan Ma, Dong-min Zhang, Yong Tang, Yang Lu, Yin Zhang, Yuan Gao, Li Xia, Ke-xiang Zhao, Li-Yin Chai, Qian Xia. Ghrelin-attenuated cognitive dysfunction in streptozotocin-induced diabetic rats. Alzheimer disease and associated disorders. vol 25. issue 4. 2012-08-13. PMID:22005105. |
we found that learning and memory level in the ghrelin treatment group improved significantly, expression of bcl-xl, bdnf, creb, p-creb, and p-erk1/2 in the hippocampus was increased in the ghrelin treatment group, and the number of apoptotic neurons in the hippocampus decreased remarkably. |
2012-08-13 |
2023-08-12 |
rat |
Lou-yan Ma, Dong-min Zhang, Yong Tang, Yang Lu, Yin Zhang, Yuan Gao, Li Xia, Ke-xiang Zhao, Li-Yin Chai, Qian Xia. Ghrelin-attenuated cognitive dysfunction in streptozotocin-induced diabetic rats. Alzheimer disease and associated disorders. vol 25. issue 4. 2012-08-13. PMID:22005105. |
our results showed that the changes of bdnf, creb, and hippocampus neuronal apoptosis might be involved in the pathogenesis of diabetic encephalopathy. |
2012-08-13 |
2023-08-12 |
rat |
Lou-yan Ma, Dong-min Zhang, Yong Tang, Yang Lu, Yin Zhang, Yuan Gao, Li Xia, Ke-xiang Zhao, Li-Yin Chai, Qian Xia. Ghrelin-attenuated cognitive dysfunction in streptozotocin-induced diabetic rats. Alzheimer disease and associated disorders. vol 25. issue 4. 2012-08-13. PMID:22005105. |
we suggested that ghrelin improved cognitive ability in streptozotocin-induced diabetic rats by improving the expressions of bdnf and creb and by attenuating hippocampus neuronal apoptosis. |
2012-08-13 |
2023-08-12 |
rat |
Ana F B Ferreira, Caroline C Real, Alice C Rodrigues, Adilson S Alves, Luiz R G Britt. Short-term, moderate exercise is capable of inducing structural, BDNF-independent hippocampal plasticity. Brain research. vol 1425. 2012-08-13. PMID:22035567. |
in this study we used a short-term, moderate intensity treadmill exercise protocol to investigate the effects of exercise on usual markers of hippocampal synaptic and structural plasticity, such as synapsin i (syn), synaptophysin (syp), neurofilaments (nf), microtubule-associated protein 2 (map2), glutamate receptor subunits glur1 and glur2/3, brain-derived neurotrophic factor (bdnf) and glial fibrillary acidic protein (gfap). |
2012-08-13 |
2023-08-12 |
rat |
Helena M Abelaira, Gislaine Z Réus, Karine F Ribeiro, Giovanni Zappellini, Andreza L Cipriano, Giselli Scaini, Emilio L Streck, João Queved. Lamotrigine treatment reverses depressive-like behavior and alters BDNF levels in the brains of maternally deprived adult rats. Pharmacology, biochemistry, and behavior. vol 101. issue 3. 2012-08-02. PMID:22306746. |
in addition to this, the bdnf and ngf levels were assessed in the prefrontal cortex, hippocampus and amygdala. |
2012-08-02 |
2023-08-12 |
rat |
Henri Autio, Kert Mätlik, Tomi Rantamäki, Lothar Lindemann, Marius C Hoener, Moses Chao, Urmas Arumäe, Eero Castré. Acetylcholinesterase inhibitors rapidly activate Trk neurotrophin receptors in the mouse hippocampus. Neuropharmacology. vol 61. issue 8. 2012-08-01. PMID:21820453. |
chronic treatment with galantamine (3 mg/kg, i.p., 14 days), did not induce changes in hippocampal ngf and bdnf synthesis or protein levels. |
2012-08-01 |
2023-08-12 |
mouse |