| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jose M Pizarro, Wenling E Chang, Mariama J Bah, Linnzi K M Wright, George A Saviolakis, Arun Alagappan, Christopher L Robison, Jinesh D Shah, James L Meyerhoff, Douglas M Cerasoli, Eric G Midboe, Lucille A Lumle. Repeated exposure to sublethal doses of the organophosphorus compound VX activates BDNF expression in mouse brain. Toxicological sciences : an official journal of the Society of Toxicology. vol 126. issue 2. 2012-07-16. PMID:22240983. |
bdnf protein expression, however, was only increased in the ca3 region of the hippocampus. |
2012-07-16 |
2023-08-12 |
mouse |
| Babak Baseri, James J Choi, Thomas Deffieux, Gesthimani Samiotaki, Yao-Sheng Tung, Oluyemi Olumolade, Scott A Small, Barclay Morrison, Elisa E Konofago. Activation of signaling pathways following localized delivery of systemically administered neurotrophic factors across the blood-brain barrier using focused ultrasound and microbubbles. Physics in medicine and biology. vol 57. issue 7. 2012-07-16. PMID:22407323. |
in this study, the efficacy of delivering exogenous bdnf to the left hippocampus is demonstrated in wild-type mice (n = 7) through the noninvasively disrupted blood-brain barrier (bbb) using focused ultrasound (fus). |
2012-07-16 |
2023-08-12 |
mouse |
| Babak Baseri, James J Choi, Thomas Deffieux, Gesthimani Samiotaki, Yao-Sheng Tung, Oluyemi Olumolade, Scott A Small, Barclay Morrison, Elisa E Konofago. Activation of signaling pathways following localized delivery of systemically administered neurotrophic factors across the blood-brain barrier using focused ultrasound and microbubbles. Physics in medicine and biology. vol 57. issue 7. 2012-07-16. PMID:22407323. |
the bdnf bioactivity was found to be preserved following delivery as assessed quantitatively by immunohistochemical detection of the ptrkb receptor and activated pakt, pmapk, and pcreb in the hippocampal neurons. |
2012-07-16 |
2023-08-12 |
mouse |
| Sandra Dieni, Tomoya Matsumoto, Martijn Dekkers, Stefanie Rauskolb, Mihai S Ionescu, Ruben Deogracias, Eckart D Gundelfinger, Masami Kojima, Sigrun Nestel, Michael Frotscher, Yves-Alain Bard. BDNF and its pro-peptide are stored in presynaptic dense core vesicles in brain neurons. The Journal of cell biology. vol 196. issue 6. 2012-07-13. PMID:22412021. |
using rigorous specificity controls, we found that antibodies reacting either with bdnf or its pro-peptide both stained large dense core vesicles in excitatory presynaptic terminals of the adult mouse hippocampus. |
2012-07-13 |
2023-08-12 |
mouse |
| S Meis, T Endres, V Lessman. Postsynaptic BDNF signalling regulates long-term potentiation at thalamo-amygdala afferents. The Journal of physiology. vol 590. issue 1. 2012-07-10. PMID:22083603. |
the neurotrophin brain-derived neurotrophic factor (bdnf) is known to regulate synaptic plasticity and memory formation in the hippocampus and the neocortex of the mammalian brain. |
2012-07-10 |
2023-08-12 |
mouse |
| Veronica Ghiglieri, Barbara Picconi, Paolo Calabres. Prenatal stress and hippocampal BDNF expression: a fading imperative. The Journal of physiology. vol 590. issue 6. 2012-07-10. PMID:22422114. |
prenatal stress and hippocampal bdnf expression: a fading imperative. |
2012-07-10 |
2023-08-12 |
Not clear |
| A R Fidalgo, M Cibelli, J P M White, I Nagy, F Noormohamed, L Benzonana, M Maze, D M. Peripheral orthopaedic surgery down-regulates hippocampal brain-derived neurotrophic factor and impairs remote memory in mouse. Neuroscience. vol 190. 2012-07-05. PMID:21699962. |
peripheral orthopaedic surgery also results in a reduction in the level of hippocampal brain-derived neurotrophic factor (bdnf) and this may contribute, in part, to the memory impairment found after such surgery. |
2012-07-05 |
2023-08-12 |
mouse |
| A R Fidalgo, M Cibelli, J P M White, I Nagy, F Noormohamed, L Benzonana, M Maze, D M. Peripheral orthopaedic surgery down-regulates hippocampal brain-derived neurotrophic factor and impairs remote memory in mouse. Neuroscience. vol 190. 2012-07-05. PMID:21699962. |
our data suggest that a reduction in the level of hippocampal bdnf and an increase in the level of hippocampal il-1β following surgery may affect the transference of fear memory in the mouse brain. |
2012-07-05 |
2023-08-12 |
mouse |
| Che-Ming Yeh, Chiung-Chun Huang, Kuei-Sen Hs. Prenatal stress alters hippocampal synaptic plasticity in young rat offspring through preventing the proteolytic conversion of pro-brain-derived neurotrophic factor (BDNF) to mature BDNF. The Journal of physiology. vol 590. issue 4. 2012-06-26. PMID:22155932. |
prenatal stress alters hippocampal synaptic plasticity in young rat offspring through preventing the proteolytic conversion of pro-brain-derived neurotrophic factor (bdnf) to mature bdnf. |
2012-06-26 |
2023-08-12 |
rat |
| M E Hopkins, R Nitecki, D J Bucc. Physical exercise during adolescence versus adulthood: differential effects on object recognition memory and brain-derived neurotrophic factor levels. Neuroscience. vol 194. 2012-06-25. PMID:21839807. |
it is well established that physical exercise can enhance hippocampal-dependent forms of learning and memory in laboratory animals, commensurate with increases in hippocampal neural plasticity (brain-derived neurotrophic factor [bdnf] mrna/protein, neurogenesis, long-term potentiation [ltp]). |
2012-06-25 |
2023-08-12 |
rat |
| M E Hopkins, R Nitecki, D J Bucc. Physical exercise during adolescence versus adulthood: differential effects on object recognition memory and brain-derived neurotrophic factor levels. Neuroscience. vol 194. 2012-06-25. PMID:21839807. |
the present study addressed these gaps in the literature by comparing the effects of 4 weeks of voluntary exercise (wheel running) during adulthood or adolescence on novel object recognition and bdnf levels in the perirhinal cortex (per) and hippocampus (hp). |
2012-06-25 |
2023-08-12 |
rat |
| Qian Chen, Zhou Zhou, Lei Zhang, Yuan Wang, Yan-wen Zhang, Min Zhong, Shang-cheng Xu, Chun-hai Chen, Li Li, Zheng-ping Y. Tau protein is involved in morphological plasticity in hippocampal neurons in response to BDNF. Neurochemistry international. vol 60. issue 3. 2012-06-25. PMID:22226842. |
tau protein is involved in morphological plasticity in hippocampal neurons in response to bdnf. |
2012-06-25 |
2023-08-12 |
rat |
| Qian Chen, Zhou Zhou, Lei Zhang, Yuan Wang, Yan-wen Zhang, Min Zhong, Shang-cheng Xu, Chun-hai Chen, Li Li, Zheng-ping Y. Tau protein is involved in morphological plasticity in hippocampal neurons in response to BDNF. Neurochemistry international. vol 60. issue 3. 2012-06-25. PMID:22226842. |
stimulation of the cultured rat hippocampal neurons with bdnf resulted in increased tau protein expression, as detected by western blotting. |
2012-06-25 |
2023-08-12 |
rat |
| Maaike Goekint, Inge Bos, Elsa Heyman, Romain Meeusen, Yvette Michotte, Sophie Sarr. Acute running stimulates hippocampal dopaminergic neurotransmission in rats, but has no influence on brain-derived neurotrophic factor. Journal of applied physiology (Bethesda, Md. : 1985). vol 112. issue 4. 2012-06-22. PMID:22134693. |
hippocampal brain-derived neurotrophic factor (bdnf) protein is increased with exercise in rats. |
2012-06-22 |
2023-08-12 |
rat |
| Maaike Goekint, Inge Bos, Elsa Heyman, Romain Meeusen, Yvette Michotte, Sophie Sarr. Acute running stimulates hippocampal dopaminergic neurotransmission in rats, but has no influence on brain-derived neurotrophic factor. Journal of applied physiology (Bethesda, Md. : 1985). vol 112. issue 4. 2012-06-22. PMID:22134693. |
hippocampal bdnf levels were not influenced, whether they were measured immediately or 2 h after the exercise protocol. |
2012-06-22 |
2023-08-12 |
rat |
| Lauren L Williamson, Agnes Chao, Staci D Bilb. Environmental enrichment alters glial antigen expression and neuroimmune function in the adult rat hippocampus. Brain, behavior, and immunity. vol 26. issue 3. 2012-06-22. PMID:22281279. |
measures of neurogenesis were not impacted by ee (brdu and dcx staining), although hippocampal bdnf mrna was significantly increased by ee. |
2012-06-22 |
2023-08-12 |
rat |
| Anton B Tonche. Brain ischemia, neurogenesis, and neurotrophic receptor expression in primates. Archives italiennes de biologie. vol 149. issue 2. 2012-06-21. PMID:21701994. |
these results implicate ngf and bdnf as regulators of postischemic glial proliferation in adult primate hippocampus. |
2012-06-21 |
2023-08-12 |
monkey |
| Enikö A Kramár, Lulu Y Chen, Julie C Lauterborn, Danielle A Simmons, Christine M Gall, Gary Lync. BDNF upregulation rescues synaptic plasticity in middle-aged ovariectomized rats. Neurobiology of aging. vol 33. issue 4. 2012-06-15. PMID:20674095. |
comparable rescue results were obtained after elevating endogenous bdnf protein levels in hippocampus with 4 daily injections of a short half-life ampakine (positive modulator of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionate [ampa]-type glutamate receptors). |
2012-06-15 |
2023-08-12 |
human |
| Sarah M Rothman, Nathan Herdener, Simonetta Camandola, Sarah J Texel, Mohamed R Mughal, Wei-Na Cong, Bronwen Martin, Mark P Mattso. 3xTgAD mice exhibit altered behavior and elevated Aβ after chronic mild social stress. Neurobiology of aging. vol 33. issue 4. 2012-06-15. PMID:21855175. |
a triple-transgenic mouse model of ad (3xtgad mice) and nontransgenic control mice were used to test for an affect of chronic mild social stress on blood glucose, plasma glucocorticoids, plasma insulin, anxiety, and hippocampal amyloid β-particle (aβ), phosphorylated tau (ptau), and brain-derived neurotrophic factor (bdnf) levels. |
2012-06-15 |
2023-08-12 |
mouse |
| Timothy R Chapman, Ruth M Barrientos, Jared T Ahrendsen, Jennifer M Hoover, Steven F Maier, Susan L Patterso. Aging and infection reduce expression of specific brain-derived neurotrophic factor mRNAs in hippocampus. Neurobiology of aging. vol 33. issue 4. 2012-06-15. PMID:21907460. |
in these animals, but not in younger (3-month-old) counterparts, a single intraperitoneal injection of e. coli leads to specific deficits in long-term memory and long-lasting synaptic plasticity in hippocampal area ca1-processes strongly dependent on brain-derived neurotrophic factor (bdnf). |
2012-06-15 |
2023-08-12 |
rat |