| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J De Vry, J Prickaerts, M Jetten, M Hulst, H W M Steinbusch, D L A van den Hove, T Schuurman, F J van der Staa. Recurrent long-lasting tethering reduces BDNF protein levels in the dorsal hippocampus and frontal cortex in pigs. Hormones and behavior. vol 62. issue 1. 2012-11-06. PMID:22584108. |
results indicate that tethering stress reduced bdnf protein levels in the dorsal hippocampus and the frontal cortex, but not in the ventral hippocampus. |
2012-11-06 |
2023-08-12 |
Not clear |
| J De Vry, J Prickaerts, M Jetten, M Hulst, H W M Steinbusch, D L A van den Hove, T Schuurman, F J van der Staa. Recurrent long-lasting tethering reduces BDNF protein levels in the dorsal hippocampus and frontal cortex in pigs. Hormones and behavior. vol 62. issue 1. 2012-11-06. PMID:22584108. |
in addition, levels of trkb, the high affinity receptor for bdnf, were increased in the dorsal hippocampus. |
2012-11-06 |
2023-08-12 |
Not clear |
| Tin-Tin Win-Shwe, Shoji Yamamoto, Yuji Fujitani, Seishiro Hirano, Hidekazu Fujimak. Nanoparticle-rich diesel exhaust affects hippocampal-dependent spatial learning and NMDA receptor subunit expression in female mice. Nanotoxicology. vol 6. issue 5. 2012-11-05. PMID:21663545. |
mice exposed to h-nrde required a longer time to reach the hidden platform and showed higher mrna expression levels of the nmda receptor subunit nr2a, the proinflammatory cytokine ccl3, and brain-derived neurotrophic factor (bdnf) in the hippocampus, compared with the findings in the control group. |
2012-11-05 |
2023-08-12 |
mouse |
| Bo Jiang, Zhe Xiong, Jun Yang, Wei Wang, Yue Wang, Zhuang-Li Hu, Fang Wang, Jian-Guo Che. Antidepressant-like effects of ginsenoside Rg1 are due to activation of the BDNF signalling pathway and neurogenesis in the hippocampus. British journal of pharmacology. vol 166. issue 6. 2012-11-05. PMID:22335772. |
antidepressant-like effects of ginsenoside rg1 are due to activation of the bdnf signalling pathway and neurogenesis in the hippocampus. |
2012-11-05 |
2023-08-12 |
mouse |
| Bo Jiang, Zhe Xiong, Jun Yang, Wei Wang, Yue Wang, Zhuang-Li Hu, Fang Wang, Jian-Guo Che. Antidepressant-like effects of ginsenoside Rg1 are due to activation of the BDNF signalling pathway and neurogenesis in the hippocampus. British journal of pharmacology. vol 166. issue 6. 2012-11-05. PMID:22335772. |
changes in hippocampal neurogenesis and spine density, the brain-derived neurotrophic factor (bdnf) signalling pathway, and serum corticosterone level after chronic stress and rg1 treatment were then investigated. |
2012-11-05 |
2023-08-12 |
mouse |
| Bo Jiang, Zhe Xiong, Jun Yang, Wei Wang, Yue Wang, Zhuang-Li Hu, Fang Wang, Jian-Guo Che. Antidepressant-like effects of ginsenoside Rg1 are due to activation of the BDNF signalling pathway and neurogenesis in the hippocampus. British journal of pharmacology. vol 166. issue 6. 2012-11-05. PMID:22335772. |
furthermore, rg1 up-regulated the bdnf signalling pathway in the hippocampus and down-regulated serum corticosterone level during the cms procedure. |
2012-11-05 |
2023-08-12 |
mouse |
| Bo Jiang, Zhe Xiong, Jun Yang, Wei Wang, Yue Wang, Zhuang-Li Hu, Fang Wang, Jian-Guo Che. Antidepressant-like effects of ginsenoside Rg1 are due to activation of the BDNF signalling pathway and neurogenesis in the hippocampus. British journal of pharmacology. vol 166. issue 6. 2012-11-05. PMID:22335772. |
conclusions and implications our results provide the first evidence that rg1 has antidepressant activity via activation of the bdnf signalling pathway and up-regulation of hippocampal neurogenesis. |
2012-11-05 |
2023-08-12 |
mouse |
| N Yamada-Goto, G Katsuura, Y Ochi, K Ebihara, T Kusakabe, K Hosoda, K Naka. Impairment of fear-conditioning responses and changes of brain neurotrophic factors in diet-induced obese mice. Journal of neuroendocrinology. vol 24. issue 8. 2012-11-05. PMID:22487415. |
bdnf content in the cerebral cortex and hippocampus of dio mice was significantly lower than that in cd mice. |
2012-11-05 |
2023-08-12 |
mouse |
| N Yamada-Goto, G Katsuura, Y Ochi, K Ebihara, T Kusakabe, K Hosoda, K Naka. Impairment of fear-conditioning responses and changes of brain neurotrophic factors in diet-induced obese mice. Journal of neuroendocrinology. vol 24. issue 8. 2012-11-05. PMID:22487415. |
the present study demonstrates that dio mice show impairment of both hippocampus-dependent contextual and amygdala-dependent cued responses in the fear-conditioning tests, as well as an imbalance in the interaction between the bdnf and nt-3 systems in the cerebral cortex, hippocampus and amygdala related to cognition and fear. |
2012-11-05 |
2023-08-12 |
mouse |
| Ingrid Reverte, Anders Bue Klein, Cecilia Ratner, José L Domingo, Maria Teresa Colomin. Behavioral phenotype and BDNF differences related to apoE isoforms and sex in young transgenic mice. Experimental neurology. vol 237. issue 1. 2012-11-05. PMID:22735491. |
we have also determined the levels of brain-derived neurotrophic factor (bdnf) and its receptor trkb in cortex and hippocampus of male and female mice carrying either genotype. |
2012-11-05 |
2023-08-12 |
mouse |
| Sarah M Rothman, Kathleen J Griffioen, Ruiqian Wan, Mark P Mattso. Brain-derived neurotrophic factor as a regulator of systemic and brain energy metabolism and cardiovascular health. Annals of the New York Academy of Sciences. vol 1264. 2012-10-25. PMID:22548651. |
by promoting synaptic plasticity and neurogenesis in the hippocampus, bdnf mediates exercise- and der-induced improvements in cognitive function and neuroprotection. |
2012-10-25 |
2023-08-12 |
Not clear |
| G D Greenberg, J A van Westerhuyzen, K L Bales, B C Traino. Is it all in the family? The effects of early social structure on neural-behavioral systems of prairie voles (Microtus ochrogaster). Neuroscience. vol 216. 2012-10-17. PMID:22561732. |
western blot analyses showed that alloparenting experience increased expression of bdnf in the bnst but decreased bdnf expression in the ca1 region of hippocampus (ca1) of nontested voles. |
2012-10-17 |
2023-08-12 |
Not clear |
| J C Walton, A J Grier, Z M Weil, R J Nelso. Photoperiod and stress regulation of corticosteroid receptor, brain-derived neurotrophic factor, and glucose transporter GLUT3 mRNA in the hippocampus of male Siberian hamsters (Phodopus sungorus). Neuroscience. vol 213. 2012-10-16. PMID:22521589. |
thus, we exposed male siberian hamsters (phodopus sungorus) to either short or long day lengths for 14 weeks to induce the full suite of adaptive responses, exposed them to 4h of restraint, and then measured relative mrna expression in the hippocampus for low- and high-affinity glucocorticoid receptors (glucocorticoid receptor (gr), mineralocorticoid receptor (mr)), brain-derived neurotrophic factor (bdnf), and the neuron-specific glucose transporter glut3. |
2012-10-16 |
2023-08-12 |
Not clear |
| Noora Raivio, Ettore Tiraboschi, Sirkku T Saarikoski, Eero Castrén, Kalervo Kiianma. Brain-derived neurotrophic factor expression after acute administration of ethanol. European journal of pharmacology. vol 687. issue 1-3. 2012-10-11. PMID:22546227. |
on the expression profile of bdnf in the rat brain by determining the bdnf mrna expression in the frontal cortex, nucleus accumbens, amygdala, hippocampus, and ventral tegmental area. |
2012-10-11 |
2023-08-12 |
rat |
| Noora Raivio, Ettore Tiraboschi, Sirkku T Saarikoski, Eero Castrén, Kalervo Kiianma. Brain-derived neurotrophic factor expression after acute administration of ethanol. European journal of pharmacology. vol 687. issue 1-3. 2012-10-11. PMID:22546227. |
ethanol decreased bdnf mrna levels dose-dependently in the hippocampus, and after the higher ethanol dose in the frontal cortex, nucleus accumbens and amygdala, while increasing them in the ventral tegmental area. |
2012-10-11 |
2023-08-12 |
rat |
| A Carballedo, F Amico, I Ugwu, A J Fagan, C Fahey, D Morris, J F Meaney, A Leemans, T Frod. Reduced fractional anisotropy in the uncinate fasciculus in patients with major depression carrying the met-allele of the Val66Met brain-derived neurotrophic factor genotype. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 159B. issue 5. 2012-10-11. PMID:22585743. |
the aim of this study was to determine the effect of val66met brain-derived neurotrophic factor (bdnf) polymorphism on the white matter fiber tracts connecting hippocampus and amygdala with the prefrontal lobe in a sample of patients with mdd and healthy controls. |
2012-10-11 |
2023-08-12 |
human |
| Yu Pei, Alicia K Smith, Yongjun Wang, Yanli Pan, Jian Yang, Qi Chen, Weigang Pan, Feng Bao, Lisha Zhao, Changle Tie, Yizheng Wang, Jian Wang, Wenfeng Zhen, Jinxia Zhou, Xin M. The brain-derived neurotrophic-factor (BDNF) val66met polymorphism is associated with geriatric depression: a meta-analysis. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 159B. issue 5. 2012-10-11. PMID:22610920. |
depression has been associated with reduced expression of brain-derived neurotrophic factor (bdnf) in the hippocampus. |
2012-10-11 |
2023-08-12 |
Not clear |
| R M Lindsay, R F Alderson, B Friedman, C Hyman, N Y Ip, M E Furth, P C Maisonpierre, S P Squinto, G D Yancopoulo. The neurotrophin family of NGF-related neurotrophic factors. Restorative neurology and neuroscience. vol 2. issue 4. 2012-10-02. PMID:21551605. |
using cultures of central nervous system neurons, we have recently established that bdnf: (i) promotes the survival and phenotypic differentiation of rat septal cholinergic neurons, a property consistent with the discovery of high levels of bdnf mrna expression within the hippocampus; (ii) promotes the survival of rat nigral dopaminergic neurons and furthermore protects these neurons from two dopaminergic neurotoxins, 6-hydroxydopamine (6-ohda) and mptp. |
2012-10-02 |
2023-08-12 |
human |
| Yuanfeng Li, Tao Li, Meizhu Zhuang, Kailiang Wang, Juan Zhang, Nian Sh. High-dose dibutyl phthalate improves performance of F1 generation male rats in spatial learning and increases hippocampal BDNF expression independent on p-CREB immunocontent. Environmental toxicology and pharmacology. vol 29. issue 1. 2012-10-02. PMID:21787579. |
high-dose dibutyl phthalate improves performance of f1 generation male rats in spatial learning and increases hippocampal bdnf expression independent on p-creb immunocontent. |
2012-10-02 |
2023-08-12 |
rat |
| Yuanfeng Li, Tao Li, Meizhu Zhuang, Kailiang Wang, Juan Zhang, Nian Sh. High-dose dibutyl phthalate improves performance of F1 generation male rats in spatial learning and increases hippocampal BDNF expression independent on p-CREB immunocontent. Environmental toxicology and pharmacology. vol 29. issue 1. 2012-10-02. PMID:21787579. |
in this study, effects of dbp on maze performance in male rats were evaluated by spatial learning tasks; the effects of dbp on the expression of brain-derived neurotrophic factor (bdnf) were also analyzed in both mrna and mature protein levels in the hippocampus, with intent to investigate the possible mechanism underlying the behavioral findings. |
2012-10-02 |
2023-08-12 |
rat |