| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Uutela, J Lindholm, V Louhivuori, H Wei, L M Louhivuori, A Pertovaara, K Akerman, E Castrén, M L Castré. Reduction of BDNF expression in Fmr1 knockout mice worsens cognitive deficits but improves hyperactivity and sensorimotor deficits. Genes, brain, and behavior. vol 11. issue 5. 2012-11-20. PMID:22435671. |
fmr1 ko mice showed age-dependent alterations in hippocampal bdnf expression that declined after the age of 4 months compared to wild-type controls. |
2012-11-20 |
2023-08-12 |
mouse |
| M Uutela, J Lindholm, V Louhivuori, H Wei, L M Louhivuori, A Pertovaara, K Akerman, E Castrén, M L Castré. Reduction of BDNF expression in Fmr1 knockout mice worsens cognitive deficits but improves hyperactivity and sensorimotor deficits. Genes, brain, and behavior. vol 11. issue 5. 2012-11-20. PMID:22435671. |
reduced bdnf decreased the survival of newborn cells in the ventral part of the hippocampus both in the presence and absence of fmrp. |
2012-11-20 |
2023-08-12 |
mouse |
| R Andero, K J Ressle. Fear extinction and BDNF: translating animal models of PTSD to the clinic. Genes, brain, and behavior. vol 11. issue 5. 2012-11-20. PMID:22530815. |
specifically, bdnf gene expression and activation of its high-affinity tropomyosin-related kinase b (trkb) receptor are necessary in the amygdala, hippocampus and prefrontal cortex for the formation of emotional memories, including fear memories. |
2012-11-20 |
2023-08-12 |
Not clear |
| Heidi A Jurgens, Rodney W Johnso. Environmental enrichment attenuates hippocampal neuroinflammation and improves cognitive function during influenza infection. Brain, behavior, and immunity. vol 26. issue 6. 2012-11-20. PMID:22687335. |
cognitive function was assessed in a reversal learning version of the morris water maze, and changes in hippocampal expression of proinflammatory cytokines (il-1β, il-6, tnf-α, ifn-α), neurotrophic (bdnf, ngf), and immunomodulatory (cd200, cx3cl1) factors were determined. |
2012-11-20 |
2023-08-12 |
mouse |
| Maha M Elbatsh, M A A Moklas, C A Marsden, D A Kendal. Antidepressant-like effects of Δ⁹-tetrahydrocannabinol and rimonabant in the olfactory bulbectomised rat model of depression. Pharmacology, biochemistry, and behavior. vol 102. issue 2. 2012-11-19. PMID:22634064. |
in intact animals, chronic thc increased brain derived neurotrophic factor (bdnf) expression levels in the hippocampus and frontal cortex but rimonabant had no effect. |
2012-11-19 |
2023-08-12 |
human |
| Maha M Elbatsh, M A A Moklas, C A Marsden, D A Kendal. Antidepressant-like effects of Δ⁹-tetrahydrocannabinol and rimonabant in the olfactory bulbectomised rat model of depression. Pharmacology, biochemistry, and behavior. vol 102. issue 2. 2012-11-19. PMID:22634064. |
ob did not affect bdnf or p-erk(1/2) expression in the hippocampus or frontal cortex and in, contrast to the intact animals, neither thc nor rimonabant altered expression in the ob rats. |
2012-11-19 |
2023-08-12 |
human |
| Masatoshi Nagano, Mingyan Liu, Hirofumi Inagaki, Tomoyuki Kawada, Hidenori Suzuk. Early intervention with fluoxetine reverses abnormalities in the serotonergic system and behavior of rats exposed prenatally to dexamethasone. Neuropharmacology. vol 63. issue 2. 2012-11-19. PMID:22710353. |
the decrease in brain-derived neurotrophic factor (bdnf) protein in the mpfc and dorsal hippocampus was also restored at pw4. |
2012-11-19 |
2023-08-12 |
rat |
| Xiang Yang Zhang, Jun Liang, Da Chun Chen, Mei Hong Xiu, Fu De Yang, Therese A Kosten, Thomas R Koste. Low BDNF is associated with cognitive impairment in chronic patients with schizophrenia. Psychopharmacology. vol 222. issue 2. 2012-11-16. PMID:22274000. |
several lines of evidence suggest that brain-derived neurotrophic factor (bdnf) plays a critical role in activity-dependent neuroplasticity underlying learning and memory in the hippocampus. |
2012-11-16 |
2023-08-12 |
Not clear |
| Rebeca S Golini, Silvia M Delgado, Lorena S Navigatore Fonzo, Ivana T Ponce, María G Lacoste, Ana C Anzulovic. Daily patterns of clock and cognition-related factors are modified in the hippocampus of vitamin A-deficient rats. Hippocampus. vol 22. issue 8. 2012-11-16. PMID:22434687. |
in this study, holtzman male rats from control and vitamin a-deficient groups were sacrificed throughout a 24-h period and hippocampus samples were isolated every 4 or 5 h. rarα and rxrβ expression level was quantified and daily expression patterns of clock bmal1, per1, rorα, and reverb genes, rorα and reverb proteins, as well as temporal expression of cognition-related rc3 and bdnf genes were determined in the hippocampus of the two groups of rats. |
2012-11-16 |
2023-08-12 |
rat |
| Rebeca S Golini, Silvia M Delgado, Lorena S Navigatore Fonzo, Ivana T Ponce, María G Lacoste, Ana C Anzulovic. Daily patterns of clock and cognition-related factors are modified in the hippocampus of vitamin A-deficient rats. Hippocampus. vol 22. issue 8. 2012-11-16. PMID:22434687. |
our results show significant daily variations of bmal1, per1, rorα, and reverb genes, rorα and reverb proteins and, consequently, daily oscillating expression of rc3 and bdnf genes in the rat hippocampus. |
2012-11-16 |
2023-08-12 |
rat |
| Rebeca S Golini, Silvia M Delgado, Lorena S Navigatore Fonzo, Ivana T Ponce, María G Lacoste, Ana C Anzulovic. Daily patterns of clock and cognition-related factors are modified in the hippocampus of vitamin A-deficient rats. Hippocampus. vol 22. issue 8. 2012-11-16. PMID:22434687. |
thus, nutritional factors, such as vitamin a and its derivatives the retinoids, might modulate daily patterns of bdnf and rc3 expression in the hippocampus, and they could be essential to maintain an optimal daily performance at molecular level in this learning-and-memory-related brain area. |
2012-11-16 |
2023-08-12 |
rat |
| Clarissa M Comim, Patrícia A Reis, Valber S Frutuoso, Gabriel R Fries, Daiane B Fraga, Flávio Kapczinski, Alexandra I Zugno, Tatiana Barichello, João Quevedo, Hugo C Castro-Faria-Net. Effects of experimental cerebral malaria in memory, brain-derived neurotrophic factor and acetylcholinesterase activity [correction for acitivity] in the hippocampus of survivor mice. Neuroscience letters. vol 523. issue 2. 2012-11-13. PMID:22750161. |
in the present work, we evaluated bdnf protein levels and ache activity in the hippocampus and habituation in an animal model of cm using c57bl/6 mice after fifteen days of the induction. |
2012-11-13 |
2023-08-12 |
mouse |
| Clarissa M Comim, Patrícia A Reis, Valber S Frutuoso, Gabriel R Fries, Daiane B Fraga, Flávio Kapczinski, Alexandra I Zugno, Tatiana Barichello, João Quevedo, Hugo C Castro-Faria-Net. Effects of experimental cerebral malaria in memory, brain-derived neurotrophic factor and acetylcholinesterase activity [correction for acitivity] in the hippocampus of survivor mice. Neuroscience letters. vol 523. issue 2. 2012-11-13. PMID:22750161. |
the results demonstrated that there was a decrease in bdnf levels in the hippocampus of c57bl/6 mice infected with pba when compared with c57bl/6 non-infected mice and c57bl/6 non-infected mice that received treatment with chloroquine. |
2012-11-13 |
2023-08-12 |
mouse |
| Clarissa M Comim, Patrícia A Reis, Valber S Frutuoso, Gabriel R Fries, Daiane B Fraga, Flávio Kapczinski, Alexandra I Zugno, Tatiana Barichello, João Quevedo, Hugo C Castro-Faria-Net. Effects of experimental cerebral malaria in memory, brain-derived neurotrophic factor and acetylcholinesterase activity [correction for acitivity] in the hippocampus of survivor mice. Neuroscience letters. vol 523. issue 2. 2012-11-13. PMID:22750161. |
in conclusion, we believe that the decreased bdnf levels in the hippocampus may be related with memory impairment without alterations on ache activity. |
2012-11-13 |
2023-08-12 |
mouse |
| Olga Carretón, Albert Giralt, Jesús F Torres-Peraza, Verónica Brito, José J Lucas, Sílvia Ginés, Josep M Canals, Jordi Alberc. Age-dependent decline of motor neocortex but not hippocampal performance in heterozygous BDNF mice correlates with a decrease of cortical PSD-95 but an increase of hippocampal TrkB levels. Experimental neurology. vol 237. issue 2. 2012-11-13. PMID:22776425. |
age-dependent decline of motor neocortex but not hippocampal performance in heterozygous bdnf mice correlates with a decrease of cortical psd-95 but an increase of hippocampal trkb levels. |
2012-11-13 |
2023-08-12 |
mouse |
| Olga Carretón, Albert Giralt, Jesús F Torres-Peraza, Verónica Brito, José J Lucas, Sílvia Ginés, Josep M Canals, Jordi Alberc. Age-dependent decline of motor neocortex but not hippocampal performance in heterozygous BDNF mice correlates with a decrease of cortical PSD-95 but an increase of hippocampal TrkB levels. Experimental neurology. vol 237. issue 2. 2012-11-13. PMID:22776425. |
interestingly, 30-week-old bdnf⁺/⁻ mice displayed increased trkb levels in the hippocampus but not in the motor neocortex, which suggests specific hippocampal compensatory mechanisms as a consequence of bdnf decrease. |
2012-11-13 |
2023-08-12 |
mouse |
| Sinead O'Donovan, Mark Kennedy, Blaithin Guinan, Shane O'Mara, Declan M McLoughli. A comparison of brief pulse and ultrabrief pulse electroconvulsive stimulation on rodent brain and behaviour. Progress in neuro-psychopharmacology & biological psychiatry. vol 37. issue 1. 2012-11-08. PMID:22230649. |
to investigate this further, we treated normal rats with a 10 session course of either bp (0.5ms), ubp (0.3ms), or sham electroconvulsive stimulation (ecs) and measured antidepressant-related changes in dentate gyrus cell proliferation and hippocampal bdnf protein levels as well as hippocampal-dependant spatial reference memory using the water plus maze and immobility time on the forced swim test. |
2012-11-08 |
2023-08-12 |
rat |
| Jin-Yi Han, Sun-Young Ahn, Eun-Hye Oh, Sang-Yoon Nam, Jin Tae Hong, Ki-Wan Oh, Mi Kyeong Le. Red ginseng extract attenuates kainate-induced excitotoxicity by antioxidative effects. Evidence-based complementary and alternative medicine : eCAM. vol 2012. 2012-11-08. PMID:23133495. |
finally, after confirming the protective effect of rge on hippocampal brain-derived neurotropic factor (bdnf) protein levels, we found that rge is active compounds mixture in ka-induced hippocampal mossy-fiber function improvement. |
2012-11-08 |
2023-08-12 |
mouse |
| J De Vry, J Prickaerts, M Jetten, M Hulst, H W M Steinbusch, D L A van den Hove, T Schuurman, F J van der Staa. Recurrent long-lasting tethering reduces BDNF protein levels in the dorsal hippocampus and frontal cortex in pigs. Hormones and behavior. vol 62. issue 1. 2012-11-06. PMID:22584108. |
recurrent long-lasting tethering reduces bdnf protein levels in the dorsal hippocampus and frontal cortex in pigs. |
2012-11-06 |
2023-08-12 |
Not clear |
| J De Vry, J Prickaerts, M Jetten, M Hulst, H W M Steinbusch, D L A van den Hove, T Schuurman, F J van der Staa. Recurrent long-lasting tethering reduces BDNF protein levels in the dorsal hippocampus and frontal cortex in pigs. Hormones and behavior. vol 62. issue 1. 2012-11-06. PMID:22584108. |
immediately after slaughter, the frontal cortex, dorsal and ventral hippocampus were dissected and protein levels of bdnf and its receptors were analyzed and compared with plasma cortisol levels and adrenal weights. |
2012-11-06 |
2023-08-12 |
Not clear |