| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| T Tuon, S S Valvassori, G C Dal Pont, C S Paganini, B G Pozzi, T F Luciano, P S Souza, J Quevedo, C T Souza, R A Pinh. Physical training prevents depressive symptoms and a decrease in brain-derived neurotrophic factor in Parkinson's disease. Brain research bulletin. vol 108. 2015-07-16. PMID:25264157. |
both types of physical exercise prevented depressive-like behavior and restored the levels of probdnf, bdnf, and trkb in the striatum and hippocampus of mice administered 6-ohda. |
2015-07-16 |
2023-08-13 |
mouse |
| Andressa Radiske, Janine I Rossato, Cristiano A Köhler, Maria Carolina Gonzalez, Jorge H Medina, Martín Cammarot. Requirement for BDNF in the reconsolidation of fear extinction. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 16. 2015-07-16. PMID:25904806. |
extinction memory reactivation increases probdnf, bdnf, and tropomyosin receptor kinase b (trkb) phosphorylation levels in dorsal ca1, while blocking bdnf maturation in the hippocampus with plasminogen activator inhibitor 1 hinders the persistence of extinction and induces the recurrence of fear. |
2015-07-16 |
2023-08-13 |
rat |
| Andressa Radiske, Janine I Rossato, Cristiano A Köhler, Maria Carolina Gonzalez, Jorge H Medina, Martín Cammarot. Requirement for BDNF in the reconsolidation of fear extinction. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 16. 2015-07-16. PMID:25904806. |
moreover, coinfusion of recombinant bdnf (0.25 μg/side) after extinction memory reactivation impedes the recovery of the avoidance response induced by inhibiting gene expression and protein synthesis in the dorsal hippocampus. |
2015-07-16 |
2023-08-13 |
rat |
| F Harrisberger, K Spalek, R Smieskova, A Schmidt, D Coynel, A Milnik, M Fastenrath, V Freytag, L Gschwind, A Walter, T Vogel, K Bendfeldt, D J-F de Quervain, A Papassotiropoulos, S Borgward. The association of the BDNF Val66Met polymorphism and the hippocampal volumes in healthy humans: a joint meta-analysis of published and new data. Neuroscience and biobehavioral reviews. vol 42. 2015-07-15. PMID:24674929. |
the association of the bdnf val66met polymorphism and the hippocampal volumes in healthy humans: a joint meta-analysis of published and new data. |
2015-07-15 |
2023-08-12 |
human |
| Luigi di Nuzzo, Rosamaria Orlando, Cristina Tognoli, Paola Di Pietro, Giuseppe Bertini, Jessica Miele, Domenico Bucci, Marta Motolese, Sergio Scaccianoce, Alessandra Caruso, Gianluca Mauro, Carmine De Lucia, Giuseppe Battaglia, Valeria Bruno, Paolo Francesco Fabene, Ferdinando Nicolett. Antidepressant activity of fingolimod in mice. Pharmacology research & perspectives. vol 3. issue 3. 2015-07-14. PMID:26171219. |
cus mice showed reduced bdnf levels and enhanced hdac2 levels in the hippocampus. |
2015-07-14 |
2023-08-13 |
mouse |
| Thomas Frodl, Norbert Skokauskas, Eva-Maria Frey, Derek Morris, Michael Gill, Angela Carballed. BDNF Val66Met genotype interacts with childhood adversity and influences the formation of hippocampal subfields. Human brain mapping. vol 35. issue 12. 2015-07-13. PMID:25044977. |
bdnf val66met genotype interacts with childhood adversity and influences the formation of hippocampal subfields. |
2015-07-13 |
2023-08-13 |
Not clear |
| Thomas Frodl, Norbert Skokauskas, Eva-Maria Frey, Derek Morris, Michael Gill, Angela Carballed. BDNF Val66Met genotype interacts with childhood adversity and influences the formation of hippocampal subfields. Human brain mapping. vol 35. issue 12. 2015-07-13. PMID:25044977. |
childhood stress and genetic factors like the val66met polymorphism of the brain derived neurotrophic factor (bdnf) gene are associated with a higher risk for developing major depressive disorder (mdd) and might also influence hippocampal changes. |
2015-07-13 |
2023-08-13 |
Not clear |
| Thomas Frodl, Norbert Skokauskas, Eva-Maria Frey, Derek Morris, Michael Gill, Angela Carballed. BDNF Val66Met genotype interacts with childhood adversity and influences the formation of hippocampal subfields. Human brain mapping. vol 35. issue 12. 2015-07-13. PMID:25044977. |
the aim of this study was to determine which hippocampal dentate gyrus and cornu ammonis subfields are altered in mdd compared to healthy controls and which subfields are affected by the bdnf val66met polymorphism and child adversity. |
2015-07-13 |
2023-08-13 |
Not clear |
| Xueqin Song, Xiaoduo Fan, Xue Li, David Kennedy, Lijuan Pang, Meina Quan, Xumei Chen, Jinsong Gao, Wei Zhang, Jianjiang Zhang, Luxian L. Serum levels of BDNF, folate and homocysteine: in relation to hippocampal volume and psychopathology in drug naïve, first episode schizophrenia. Schizophrenia research. vol 159. issue 1. 2015-07-13. PMID:25128453. |
serum levels of bdnf, folate and homocysteine: in relation to hippocampal volume and psychopathology in drug naïve, first episode schizophrenia. |
2015-07-13 |
2023-08-13 |
Not clear |
| Xueqin Song, Xiaoduo Fan, Xue Li, David Kennedy, Lijuan Pang, Meina Quan, Xumei Chen, Jinsong Gao, Wei Zhang, Jianjiang Zhang, Luxian L. Serum levels of BDNF, folate and homocysteine: in relation to hippocampal volume and psychopathology in drug naïve, first episode schizophrenia. Schizophrenia research. vol 159. issue 1. 2015-07-13. PMID:25128453. |
the present study was to examine serum levels of brain-derived neurotrophic factor (bdnf), folate, homocysteine (hcy), and their relationships with hippocampal volume and psychopathology in drug naïve, first episode schizophrenia. |
2015-07-13 |
2023-08-13 |
Not clear |
| Yuehan Zhao, Yongdong Zhang, Fang Pa. The effects of EGb761 on lipopolysaccharide-induced depressive-like behaviour in C57BL/6J mice. Central-European journal of immunology. vol 40. issue 1. 2015-07-09. PMID:26155178. |
we found that lps administration induced significant depressive-like behaviours, higher levels of tumour necrosis factor α (tnf-α), interleukin (il) 1β, il-6, and il-17a, but lower levels of bdnf and il-10 in hippocampus tissue homogenate of the mice from the vehicle group compared to the control mice. |
2015-07-09 |
2023-08-13 |
mouse |
| Yuehan Zhao, Yongdong Zhang, Fang Pa. The effects of EGb761 on lipopolysaccharide-induced depressive-like behaviour in C57BL/6J mice. Central-European journal of immunology. vol 40. issue 1. 2015-07-09. PMID:26155178. |
pretreatment with middle dose (100 mg/kg/day) and high dose (150 mg/kg/day) of egb761 significantly attenuated depressive-like behaviours without affecting spontaneous locomotor activity, and inhibited the changes of hippocampal cytokines and bdnf induced by lps administration. |
2015-07-09 |
2023-08-13 |
mouse |
| MuHuo Ji, Lin Dong, Min Jia, WenXue Liu, MingQiang Zhang, LinSha Ju, JiaoJiao Yang, Zhongcong Xie, JianJun Yan. Epigenetic enhancement of brain-derived neurotrophic factor signaling pathway improves cognitive impairments induced by isoflurane exposure in aged rats. Molecular neurobiology. vol 50. issue 3. 2015-07-08. PMID:24553857. |
our data showed that repeated isoflurane exposure significantly decreased the freezing time to context and the freezing time to tone in the fear conditioning test, which was associated with upregulated histone deacetylase 2, reduced histone acetylation, and increased inflammation and apoptosis in the hippocampus, and impairments of brain-derived neurotrophic factor (bdnf)-tyrosine kinase receptor b (trkb) and the downstream signaling pathway phospho-calmodulin-dependent protein kinase and phospho-camp response element-binding protein. |
2015-07-08 |
2023-08-12 |
rat |
| Isabel Vieira de Assis Lima, Alline Cristina Campos, Aline Silva Miranda, Érica Leandro Marciano Vieira, Flávia Amaral-Martins, Juliana Priscila Vago, Rebeca Priscila de Melo Santos, Lirlândia Pires Sousa, Luciene Bruno Vieira, Mauro Martins Teixeira, Bernd L Fiebich, Márcio Flávio Dutra Moraes, Antonio Lucio Teixeira, Antonio Carlos Pinheiro de Oliveir. PI3Kγ deficiency enhances seizures severity and associated outcomes in a mouse model of convulsions induced by intrahippocampal injection of pilocarpine. Experimental neurology. vol 267. 2015-07-06. PMID:25749189. |
levels of bdnf were significantly increased in the hippocampus of wt and pi3kγ(-/-) mice, although in the prefrontal cortex, only pi3kγ(-/-) animals showed significant increase in the levels of this neurotrophic factor. |
2015-07-06 |
2023-08-13 |
mouse |
| Indrek Heinla, Este Leidmaa, Karina Kongi, Airi Pennert, Jürgen Innos, Kaarel Nurk, Triin Tekko, Katyayani Singh, Taavi Vanaveski, Riin Reimets, Merle Mandel, Aavo Lang, Kersti Lilleväli, Allen Kaasik, Eero Vasar, Mari-Anne Philip. Gene expression patterns and environmental enrichment-induced effects in the hippocampi of mice suggest importance of Lsamp in plasticity. Frontiers in neuroscience. vol 9. 2015-07-03. PMID:26136648. |
we provide evidence that lsamp modulates enrichment-induced activation of bdnf as the enrichment-induced elevation of bdnf in the hippocampus is significantly diminished in lsamp-deficient mice; furthermore, a significant correlation was found between the expression levels of lsamp and bdnf transcripts in the hippocampus and frontal cortex. |
2015-07-03 |
2023-08-13 |
mouse |
| Ana Rita Santos, Miranda Mele, Sandra H Vaz, Blanka Kellermayer, Maddalena Grimaldi, Mariana Colino-Oliveira, Diogo M Rombo, Diogo Comprido, Ana M Sebastião, Carlos B Duart. Differential role of the proteasome in the early and late phases of BDNF-induced facilitation of LTP. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 8. 2015-06-29. PMID:25716833. |
accordingly, bdnf downregulated the proteasome activity in cultured hippocampal neurons and in hippocampal synaptoneurosomes. |
2015-06-29 |
2023-08-13 |
rat |
| Andrés P Varani, Lirane Moutinho Machado, Graciela N Baleri. Baclofen prevented the changes in c-Fos and brain-derived neutrophic factor expressions during mecamylamine-precipitated nicotine withdrawal in mice. Synapse (New York, N.Y.). vol 68. issue 11. 2015-06-26. PMID:25042794. |
conversely, bdnf expression decreased in the ca1 and ca3 area of the hippocampus, the hb, and caudate putamen (cpu) during nic withdrawal. |
2015-06-26 |
2023-08-13 |
mouse |
| J Bryce Ortiz, Coy M Mathewson, Ann N Hoffman, Paul D Hanavan, Ernest F Terwilliger, Cheryl D Conra. Hippocampal brain-derived neurotrophic factor mediates recovery from chronic stress-induced spatial reference memory deficits. The European journal of neuroscience. vol 40. issue 9. 2015-06-25. PMID:25156382. |
here, we investigated whether brain-derived neurotrophic factor (bdnf), a protein important for hippocampal function, would alter the recovery from chronic stress-induced spatial memory deficits. |
2015-06-25 |
2023-08-13 |
rat |
| J Bryce Ortiz, Coy M Mathewson, Ann N Hoffman, Paul D Hanavan, Ernest F Terwilliger, Cheryl D Conra. Hippocampal brain-derived neurotrophic factor mediates recovery from chronic stress-induced spatial reference memory deficits. The European journal of neuroscience. vol 40. issue 9. 2015-06-25. PMID:25156382. |
adult male sprague-dawley rats were infused into the dorsal hippocampal cornu ammonis (ca)3 region with an adeno-associated viral vector containing the sequence for a short hairpin rna (shrna) directed against bdnf or a scrambled sequence (scr). |
2015-06-25 |
2023-08-13 |
rat |
| J Bryce Ortiz, Coy M Mathewson, Ann N Hoffman, Paul D Hanavan, Ernest F Terwilliger, Cheryl D Conra. Hippocampal brain-derived neurotrophic factor mediates recovery from chronic stress-induced spatial reference memory deficits. The European journal of neuroscience. vol 40. issue 9. 2015-06-25. PMID:25156382. |
the stress effects were specific for the reference memory domain, but knockdown of hippocampal bdnf in unstressed controls briefly disrupted spatial working memory as measured by repeated entry errors on day 2 of training. |
2015-06-25 |
2023-08-13 |
rat |