| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J Bryce Ortiz, Coy M Mathewson, Ann N Hoffman, Paul D Hanavan, Ernest F Terwilliger, Cheryl D Conra. Hippocampal brain-derived neurotrophic factor mediates recovery from chronic stress-induced spatial reference memory deficits. The European journal of neuroscience. vol 40. issue 9. 2015-06-25. PMID:25156382. |
these results demonstrated that hippocampal bdnf was necessary for the recovery from stress-induced hippocampal-dependent spatial memory deficits in the reference memory domain. |
2015-06-25 |
2023-08-13 |
rat |
| Xiao-Dan Han, Min Li, Xiao-Guang Zhang, Zhang-Gang Xue, Jing Can. Single sevoflurane exposure increases methyl-CpG island binding protein 2 phosphorylation in the hippocampus of developing mice. Molecular medicine reports. vol 11. issue 1. 2015-06-25. PMID:25338822. |
methyl-cpg island binding protein 2 (mecp2), camp response element-binding protein (creb) and brain-derived neurotrophic factor (bdnf) expression in the hippocampus was measured by western blotting. |
2015-06-25 |
2023-08-13 |
mouse |
| Monzurul Amin Roni, Shafiqur Rahma. The effects of lobeline on depression-like behavior and hippocampal cell proliferation following chronic stress in mice. Neuroscience letters. vol 584. 2015-06-23. PMID:25451721. |
the present study examined the effects of lobeline on chronic unpredictable stress (cus)-induced depression-like behavior, deficits in brain-derived neurotrophic factor (bdnf) expression and cell proliferation in the hippocampus. |
2015-06-23 |
2023-08-13 |
mouse |
| Monzurul Amin Roni, Shafiqur Rahma. The effects of lobeline on depression-like behavior and hippocampal cell proliferation following chronic stress in mice. Neuroscience letters. vol 584. 2015-06-23. PMID:25451721. |
twenty-four hour following lobeline or saline treatment, bdnf expression or cell proliferation was measured in the hippocampus using western blotting and bromodeoxyuridine immunohistochemistry, respectively. |
2015-06-23 |
2023-08-13 |
mouse |
| Monzurul Amin Roni, Shafiqur Rahma. The effects of lobeline on depression-like behavior and hippocampal cell proliferation following chronic stress in mice. Neuroscience letters. vol 584. 2015-06-23. PMID:25451721. |
lobeline (1 mg/kg) treatment prevented cus-induced reduction in bdnf expression and cell proliferation in the hippocampus. |
2015-06-23 |
2023-08-13 |
mouse |
| Monzurul Amin Roni, Shafiqur Rahma. The effects of lobeline on depression-like behavior and hippocampal cell proliferation following chronic stress in mice. Neuroscience letters. vol 584. 2015-06-23. PMID:25451721. |
overall, our findings suggest that antidepressant-like effects of lobeline could involve nachr mediated signaling, bdnf expression, and/or hippocampal cell proliferation. |
2015-06-23 |
2023-08-13 |
mouse |
| Atish Prakash, Anil Kuma. Implicating the role of lycopene in restoration of mitochondrial enzymes and BDNF levels in β-amyloid induced Alzheimer׳s disease. European journal of pharmacology. vol 741. 2015-06-22. PMID:25066110. |
the rats were sacrificed on the 21st day following the last behavioral test and cytoplasmic fractions of hippocampus were prepared for the quantification of acetylcholinesterase, oxidative stress parameter, mitochondrial enzymes, and inflammatory mediator like tnf-α, il-6 activities, caspase-3 and bdnf. |
2015-06-22 |
2023-08-13 |
rat |
| Jin Sun, Yunxia Qu, Huiming He, Xiaolei Fan, Yuanhua Qin, Weifeng Mao, Lixin X. Protective effect of polydatin on learning and memory impairments in neonatal rats with hypoxic‑ischemic brain injury by up‑regulating brain‑derived neurotrophic factor. Molecular medicine reports. vol 10. issue 6. 2015-06-19. PMID:25241777. |
of note, polydatin was found to upregulate the expression of hippocampal brain‑derived neurotrophic factor (bdnf) in rats with hibi. |
2015-06-19 |
2023-08-13 |
rat |
| Tae-Woon Kim, Hyun-Sik Kang, Joon-Ki Park, Sam-Jun Lee, Sang-Bin Baek, Chang-Ju Ki. Voluntary wheel running ameliorates symptoms of MK-801-induced schizophrenia in mice. Molecular medicine reports. vol 10. issue 6. 2015-06-19. PMID:25323073. |
for investigating the biochemical parameters, nmda receptor expression in the hippocampal ca2‑3 regions and prefrontal cortex was detected by nmda immunofluorescence and bdnf expression in the hippocampus was measured using western blot analysis. |
2015-06-19 |
2023-08-13 |
mouse |
| Sophie St-Cyr, Patrick O McGowa. Programming of stress-related behavior and epigenetic neural gene regulation in mice offspring through maternal exposure to predator odor. Frontiers in behavioral neuroscience. vol 9. 2015-06-17. PMID:26082698. |
in the hippocampus of adult female offspring, decreased brain-derived neurotrophic factor (bdnf) transcript abundance was correlated with a site-specific decrease in dna methylation in bdnf exon iv, indicating the potential contribution of this epigenetic mechanism to maternal programming by maternal predator odor exposure. |
2015-06-17 |
2023-08-13 |
mouse |
| Li-Ming Zhang, Wen-Wen Zhou, Ya-Jun Ji, Ying Li, Nan Zhao, Hong-Xia Chen, Rui Xue, Xin-Guo Mei, You-Zhi Zhang, Heng-Lin Wang, Yun-Feng L. Anxiolytic effects of ketamine in animal models of posttraumatic stress disorder. Psychopharmacology. vol 232. issue 4. 2015-06-12. PMID:25231918. |
the effect of ketamine on behavioral changes after exposure to tds was also investigated, and the levels of brain-derived neurotrophic factor (bdnf) in the hippocampus were measured. |
2015-06-12 |
2023-08-13 |
mouse |
| Li-Ming Zhang, Wen-Wen Zhou, Ya-Jun Ji, Ying Li, Nan Zhao, Hong-Xia Chen, Rui Xue, Xin-Guo Mei, You-Zhi Zhang, Heng-Lin Wang, Yun-Feng L. Anxiolytic effects of ketamine in animal models of posttraumatic stress disorder. Psychopharmacology. vol 232. issue 4. 2015-06-12. PMID:25231918. |
furthermore, ketamine normalized the decreased bdnf level in the hippocampus in post-tds rats. |
2015-06-12 |
2023-08-13 |
mouse |
| Li-Ming Zhang, Wen-Wen Zhou, Ya-Jun Ji, Ying Li, Nan Zhao, Hong-Xia Chen, Rui Xue, Xin-Guo Mei, You-Zhi Zhang, Heng-Lin Wang, Yun-Feng L. Anxiolytic effects of ketamine in animal models of posttraumatic stress disorder. Psychopharmacology. vol 232. issue 4. 2015-06-12. PMID:25231918. |
taken together, these results suggest that ketamine exerts a therapeutic effect on ptsd that might be at least partially mediated by an influence on bdnf signaling in the hippocampus. |
2015-06-12 |
2023-08-13 |
mouse |
| James O Fajemiroye, Pablinny M Galdino, Iziara F Florentino, Fabio F Da Rocha, Paulo C Ghedini, Prabhakar R Polepally, Jordan K Zjawiony, Elson A Cost. Plurality of anxiety and depression alteration mechanism by oleanolic acid. Journal of psychopharmacology (Oxford, England). vol 28. issue 10. 2015-06-09. PMID:24920136. |
pretreatment (intraperitoneal) of animals with pentylenetetrazole (ptz) 20 mg/kg, 1-(2-methoxyphenyl)-4-[4- (2-phthalimido) butyl]piperazine hydrobromide (nan-190) 0.5 mg/kg, p-chlorophenylalanine methyl ester (pcpa) 100 mg/kg or α-methyl-p-tyrosine (ampt) 100 mg/kg, way100635 (way) 0.3 mg/kg, prazosin (praz) 1 mg/kg, yohimbine 2 mg/kg as well as monoamine oxidase assay and hippocampal brain-derived neurotrophic factor (bdnf) quantification were carried out. |
2015-06-09 |
2023-08-13 |
mouse |
| James O Fajemiroye, Pablinny M Galdino, Iziara F Florentino, Fabio F Da Rocha, Paulo C Ghedini, Prabhakar R Polepally, Jordan K Zjawiony, Elson A Cost. Plurality of anxiety and depression alteration mechanism by oleanolic acid. Journal of psychopharmacology (Oxford, England). vol 28. issue 10. 2015-06-09. PMID:24920136. |
although monoamine oxidase activity remained unaltered by oleanolic acid, chronic administration of oleanolic acid augmented hippocampal bdnf level. |
2015-06-09 |
2023-08-13 |
mouse |
| Xiao Huang, Yue-Shi Mao, Chao Li, Hao Wang, Jian-Lin J. Venlafaxine inhibits apoptosis of hippocampal neurons by up-regulating brain-derived neurotrophic factor in a rat depression model. International journal of clinical and experimental pathology. vol 7. issue 8. 2015-06-09. PMID:25197330. |
to study the effect of venlafaxine on the expression of brain-derived neurotrophic factor (bdnf) in rat hippocampal neurons, as well as its inhibitory effect on apoptosis of hippocampal neurons. |
2015-06-09 |
2023-08-13 |
rat |
| J K Wallingford, S Deurveilher, R W Currie, J P Fawcett, K Semb. Increases in mature brain-derived neurotrophic factor protein in the frontal cortex and basal forebrain during chronic sleep restriction in rats: possible role in initiating allostatic adaptation. Neuroscience. vol 277. 2015-06-08. PMID:25010399. |
mature bdnf protein levels were measured in the frontal cortex and basal forebrain, two brain regions involved in sleep and eeg regulation, and the hippocampus, using western blot analysis. |
2015-06-08 |
2023-08-13 |
rat |
| Mark R Zielinski, Youngsoo Kim, Svetlana A Karpova, Robert W McCarley, Robert E Strecker, Dmitry Gerashchenk. Chronic sleep restriction elevates brain interleukin-1 beta and tumor necrosis factor-alpha and attenuates brain-derived neurotrophic factor expression. Neuroscience letters. vol 580. 2015-06-08. PMID:25093703. |
il-1β, tnf-α, and bdnf mrna levels were determined in the somatosensory cortex, frontal cortex, hippocampus, and basal forebrain. |
2015-06-08 |
2023-08-13 |
rat |
| Mark R Zielinski, Youngsoo Kim, Svetlana A Karpova, Robert W McCarley, Robert E Strecker, Dmitry Gerashchenk. Chronic sleep restriction elevates brain interleukin-1 beta and tumor necrosis factor-alpha and attenuates brain-derived neurotrophic factor expression. Neuroscience letters. vol 580. 2015-06-08. PMID:25093703. |
in contrast, bdnf mrna levels were similar to baseline values in the cortex after 1 day of sr and significantly lower than baseline values in the hippocampus after 5 days of sr. |
2015-06-08 |
2023-08-13 |
rat |
| Mark R Zielinski, Youngsoo Kim, Svetlana A Karpova, Robert W McCarley, Robert E Strecker, Dmitry Gerashchenk. Chronic sleep restriction elevates brain interleukin-1 beta and tumor necrosis factor-alpha and attenuates brain-derived neurotrophic factor expression. Neuroscience letters. vol 580. 2015-06-08. PMID:25093703. |
further, the csr-induced enhancements in brain inflammatory molecules and attenuations in hippocampal bdnf might contribute to neurocognitive and vigilance detriments that occur from csr. |
2015-06-08 |
2023-08-13 |
rat |