| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Dongmei Duan, Liping Chen, Xiuyan Yang, Ya Tu, Shuang Jia. Antidepressant-like effect of essential oil isolated from Toona ciliata Roem. var. yunnanensis. Journal of natural medicines. vol 69. issue 2. 2015-06-02. PMID:25465853. |
additionally, the contents of da, ne, 5-ht, and bdnf in the hippocampus of cms rats could be increased by treatment with essential oil at doses of 20, 40, and 80 mg/kg. |
2015-06-02 |
2023-08-13 |
rat |
| Xiao Huang, Yue-Shi Mao, Chao Li, Hao Wang, Jian-Lin J. Venlafaxine inhibits apoptosis of hippocampal neurons by up-regulating brain-derived neurotrophic factor in a rat depression model. Die Pharmazie. vol 69. issue 12. 2015-06-02. PMID:25951665. |
the effect of venlafaxine on the expression of brain-derived neurotrophic factor (bdnf) in rat hippocampal neurons was studied, as well as its inhibitory effect on apoptosis of hippocampal neurons. |
2015-06-02 |
2023-08-13 |
rat |
| Xiao Huang, Yue-Shi Mao, Chao Li, Hao Wang, Jian-Lin J. Venlafaxine inhibits apoptosis of hippocampal neurons by up-regulating brain-derived neurotrophic factor in a rat depression model. Die Pharmazie. vol 69. issue 12. 2015-06-02. PMID:25951665. |
the rat hippocampal tissue was sliced, stained and observed for bdnf distribution by immunohistochemistry. |
2015-06-02 |
2023-08-13 |
rat |
| Xiao Huang, Yue-Shi Mao, Chao Li, Hao Wang, Jian-Lin J. Venlafaxine inhibits apoptosis of hippocampal neurons by up-regulating brain-derived neurotrophic factor in a rat depression model. Die Pharmazie. vol 69. issue 12. 2015-06-02. PMID:25951665. |
bdnf expression in the hippocampal tissue was detected by western blot. |
2015-06-02 |
2023-08-13 |
rat |
| Xiao Huang, Yue-Shi Mao, Chao Li, Hao Wang, Jian-Lin J. Venlafaxine inhibits apoptosis of hippocampal neurons by up-regulating brain-derived neurotrophic factor in a rat depression model. Die Pharmazie. vol 69. issue 12. 2015-06-02. PMID:25951665. |
immunohistochemistry showed that venlafaxine markedly increased bdnf expression in the rat hippocampus. |
2015-06-02 |
2023-08-13 |
rat |
| Xiao Huang, Yue-Shi Mao, Chao Li, Hao Wang, Jian-Lin J. Venlafaxine inhibits apoptosis of hippocampal neurons by up-regulating brain-derived neurotrophic factor in a rat depression model. Die Pharmazie. vol 69. issue 12. 2015-06-02. PMID:25951665. |
venlafaxine improved the expression of bdnf by influencing the pi3k/pkb/enos pathway and repressed the apoptosis of hippocampal neurons. |
2015-06-02 |
2023-08-13 |
rat |
| Jan Bakos, Zuzana Lestanova, Vladimir Strbak, Tomas Havranek, Zuzana Bacov. Neonatal manipulation of oxytocin prevents lipopolysaccharide-induced decrease in gene expression of growth factors in two developmental stages of the female rat. Neuropeptides. vol 48. issue 5. 2015-05-27. PMID:25047873. |
oxytocin significantly increased gene expression of bdnf in the right hippocampus in 21-day and 2-month old rats of both sexes. |
2015-05-27 |
2023-08-13 |
rat |
| Katrina L Paumier, Caryl E Sortwell, Lalitha Madhavan, Brian Terpstra, Brian F Daley, Timothy J Collie. Tricyclic antidepressant treatment evokes regional changes in neurotrophic factors over time within the intact and degenerating nigrostriatal system. Experimental neurology. vol 266. 2015-05-26. PMID:25681575. |
the left and right hemispheres of the substantia nigra, striatum, frontal cortex, piriform cortex, hippocampus, and anterior cingulate cortex were dissected, and bdnf and gdnf levels were measured with elisa. |
2015-05-26 |
2023-08-13 |
rat |
| Emily E Noble, Vijayakumar Mavanji, Morgan R Little, Charles J Billington, Catherine M Kotz, ChuanFeng Wan. Exercise reduces diet-induced cognitive decline and increases hippocampal brain-derived neurotrophic factor in CA3 neurons. Neurobiology of learning and memory. vol 114. 2015-05-22. PMID:24755094. |
both diet and exercise influence expression of hippocampal brain-derived neurotrophic factor (bdnf), which is associated with improved cognition. |
2015-05-22 |
2023-08-13 |
Not clear |
| Emily E Noble, Vijayakumar Mavanji, Morgan R Little, Charles J Billington, Catherine M Kotz, ChuanFeng Wan. Exercise reduces diet-induced cognitive decline and increases hippocampal brain-derived neurotrophic factor in CA3 neurons. Neurobiology of learning and memory. vol 114. 2015-05-22. PMID:24755094. |
we hypothesized that exercise reverses diet-induced cognitive decline while increasing hippocampal bdnf. |
2015-05-22 |
2023-08-13 |
Not clear |
| Wen-Jing Yan, Ying-Chun Tan, Ji-Cheng Xu, Xian-Ping Tang, Chong Zhang, Peng-Bo Zhang, Ze-Qiang Re. Protective effects of silibinin and its possible mechanism of action in mice exposed to chronic unpredictable mild stress. Biomolecules & therapeutics. vol 23. issue 3. 2015-05-21. PMID:25995823. |
furthermore, silibinin treatment increased the levels of brain-derived neurotrophic factor (bdnf), serotonin (5-ht) and norepinephrine (ne) in the prefrontal cortex and hippocampus. |
2015-05-21 |
2023-08-13 |
mouse |
| Gu Ping, Wu Qian, Ge Song, Shi Zhaochu. Valsartan reverses depressive/anxiety-like behavior and induces hippocampal neurogenesis and expression of BDNF protein in unpredictable chronic mild stress mice. Pharmacology, biochemistry, and behavior. vol 124. 2015-05-19. PMID:24844704. |
valsartan reverses depressive/anxiety-like behavior and induces hippocampal neurogenesis and expression of bdnf protein in unpredictable chronic mild stress mice. |
2015-05-19 |
2023-08-13 |
mouse |
| Gu Ping, Wu Qian, Ge Song, Shi Zhaochu. Valsartan reverses depressive/anxiety-like behavior and induces hippocampal neurogenesis and expression of BDNF protein in unpredictable chronic mild stress mice. Pharmacology, biochemistry, and behavior. vol 124. 2015-05-19. PMID:24844704. |
the effects of valsartan on antidepression/antianxiety, hippocampal neurogenesis and bdnf expression were evaluated in these behavior tests. |
2015-05-19 |
2023-08-13 |
mouse |
| Gu Ping, Wu Qian, Ge Song, Shi Zhaochu. Valsartan reverses depressive/anxiety-like behavior and induces hippocampal neurogenesis and expression of BDNF protein in unpredictable chronic mild stress mice. Pharmacology, biochemistry, and behavior. vol 124. 2015-05-19. PMID:24844704. |
in this study, an impairment in hippocampal neurogenesis which parallelled with a reduced bdnf level in the hippocampus was observed in the mice that were treated with ucms for 6 weeks. |
2015-05-19 |
2023-08-13 |
mouse |
| Gu Ping, Wu Qian, Ge Song, Shi Zhaochu. Valsartan reverses depressive/anxiety-like behavior and induces hippocampal neurogenesis and expression of BDNF protein in unpredictable chronic mild stress mice. Pharmacology, biochemistry, and behavior. vol 124. 2015-05-19. PMID:24844704. |
these findings demonstrate that valsartan is an effective antidepressant/antianxiety reagent and can promote the hippocampal neurogenesis and expression of bdnf. |
2015-05-19 |
2023-08-13 |
mouse |
| Jeffrey Helgager, Yang Zhong Huang, James O Mcnamar. Brain-derived neurotrophic factor but not vesicular zinc promotes TrkB activation within mossy fibers of mouse hippocampus in vivo. The Journal of comparative neurology. vol 522. issue 17. 2015-05-19. PMID:25043764. |
we found that conditional deletion of bdnf resulted in a reduction of py816 in axons and synaptic boutons of hippocampal mossy fibers, thereby implicating bdnf in activation of trkb in vivo. |
2015-05-19 |
2023-08-13 |
mouse |
| Jeffrey Helgager, Yang Zhong Huang, James O Mcnamar. Brain-derived neurotrophic factor but not vesicular zinc promotes TrkB activation within mossy fibers of mouse hippocampus in vivo. The Journal of comparative neurology. vol 522. issue 17. 2015-05-19. PMID:25043764. |
marked increases of bdnf content were evident within the hippocampus of znt3 knockout mice and genetic elimination of bdnf reduced py816 immunoreactivity in these mice, implicating bdnf in enhanced trkb activation mediated by vesicular zinc depletion. |
2015-05-19 |
2023-08-13 |
mouse |
| Jeffrey Helgager, Yang Zhong Huang, James O Mcnamar. Brain-derived neurotrophic factor but not vesicular zinc promotes TrkB activation within mossy fibers of mouse hippocampus in vivo. The Journal of comparative neurology. vol 522. issue 17. 2015-05-19. PMID:25043764. |
these findings support the conclusion that bdnf but not vesicular zinc activates trkb in hippocampal mossy fiber axons under physiological conditions. |
2015-05-19 |
2023-08-13 |
mouse |
| Shui-Jin Yang, Hai-Yang Yu, Dan-Yu Kang, Zhan-Qiang Ma, Rong Qu, Qiang Fu, Shi-Ping M. Antidepressant-like effects of salidroside on olfactory bulbectomy-induced pro-inflammatory cytokine production and hyperactivity of HPA axis in rats. Pharmacology, biochemistry, and behavior. vol 124. 2015-05-19. PMID:25101546. |
western blot showed that sa could markedly increase glucocorticoid receptor (gr) and brain-derived neurotrophic factor (bdnf) expression in the hippocampus. |
2015-05-19 |
2023-08-13 |
rat |
| Jia-Ling Yu, Li Ma, Lan Ma, Ye-Zheng Ta. [Voluntary wheel running enhances cell proliferation and expression levels of BDNF, IGF1 and WNT4 in dentate gyrus of adult mice]. Sheng li xue bao : [Acta physiologica Sinica]. vol 66. issue 5. 2015-05-16. PMID:25332001. |
these results indicate that the increase of adult hippocampal neurogenesis caused by voluntary wheel running for 15 days might be through up-regulating bdnf, igf1 and wnt4 in dentate gyrus. |
2015-05-16 |
2023-08-13 |
mouse |