| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ulrika Beitnere, Zane Dzirkale, Sergejs Isajevs, Juris Rumaks, Simons Svirskis, Vija Klus. Carnitine congener mildronate protects against stress- and haloperidol-induced impairment in memory and brain protein expression in rats. European journal of pharmacology. vol 745. 2015-08-24. PMID:25446926. |
haloperidol decrease by a third hippocampal bdnf and acetylcholine esterase (but not gad67) expression, which was normalized by mildronate; it also reversed the haloperidol-induced memory impairment in barnes test. |
2015-08-24 |
2023-08-13 |
rat |
| Sara Mehrpouya, Arezo Nahavandi, Fatemeh Khojasteh, Mansoureh Soleimani, Mohammad Ahmadi, Mahmood Barat. Iron administration prevents BDNF decrease and depressive-like behavior following chronic stress. Brain research. vol 1596. 2015-08-24. PMID:25451115. |
serum interleukin-6 (enzyme-linked immune sorbent assay), hippocampus iron content (atomic absorption spectrometry), brain-derived neurotrophic factor (bdnf) gene expression (real-time polymerase chain reaction), ca1 pyramidal cell count (nissl method) and a behavioral test (forced swimming test) were evaluated. |
2015-08-24 |
2023-08-13 |
rat |
| Dafu Yu, Heng Zhou, Yuan Yang, Yong Jiang, Tianchao Wang, Liang Lv, Qixin Zhou, Yuexiong Yang, Xuexian Dong, Jianfeng He, Xiaoyan Huang, Jijun Chen, Kunhua Wu, Lin Xu, Rongrong Ma. The bidirectional effects of hypothyroidism and hyperthyroidism on anxiety- and depression-like behaviors in rats. Hormones and behavior. vol 69. 2015-08-24. PMID:25623236. |
diminished levels of brain serotonin (5-ht) and increased levels of hippocampal brain-derived neurotrophic factor (bdnf) were found in the hypothyroid rats compared to the control saline-vehicle administered rats. |
2015-08-24 |
2023-08-13 |
rat |
| Dafu Yu, Heng Zhou, Yuan Yang, Yong Jiang, Tianchao Wang, Liang Lv, Qixin Zhou, Yuexiong Yang, Xuexian Dong, Jianfeng He, Xiaoyan Huang, Jijun Chen, Kunhua Wu, Lin Xu, Rongrong Ma. The bidirectional effects of hypothyroidism and hyperthyroidism on anxiety- and depression-like behaviors in rats. Hormones and behavior. vol 69. 2015-08-24. PMID:25623236. |
the hyperthyroid rats exhibited higher anxiety- and depression-like behaviors, higher brain 5-ht level, and lower hippocampal bdnf levels than the controls. |
2015-08-24 |
2023-08-13 |
rat |
| Dafu Yu, Heng Zhou, Yuan Yang, Yong Jiang, Tianchao Wang, Liang Lv, Qixin Zhou, Yuexiong Yang, Xuexian Dong, Jianfeng He, Xiaoyan Huang, Jijun Chen, Kunhua Wu, Lin Xu, Rongrong Ma. The bidirectional effects of hypothyroidism and hyperthyroidism on anxiety- and depression-like behaviors in rats. Hormones and behavior. vol 69. 2015-08-24. PMID:25623236. |
together, our results suggest that hypothyroidism and hyperthyroidism have bidirectional effects on anxiety- and depression-like behaviors in rats, possibly by modulating hippocampal bdnf levels. |
2015-08-24 |
2023-08-13 |
rat |
| Tatiana Barichello, Joao Carlos Nepomuceno Goncalves, Jaqueline da Silva Generoso, Lutiana Roque Simoes, Michael Hikaru Tashiro, Jessica de Assis Goularte, Francieli Vuolo, David Henrique Rodrigues, Marcia Carvalho Vilela, Fabricia Petronilho, Antonio Lucio Teixeira, Joao Queved. Protection of blood brain barrier integrity and modulation of inflammatory mediators during treatment of pneumococcal meningitis with daptomycin or ceftriaxone. Current neurovascular research. vol 11. issue 3. 2015-08-21. PMID:24845856. |
in the hippocampus, brain-derived neurotrophic factor (bdnf), tumour necrosis factor alpha (tnf-α), interleukin-6 (il-6) and il-10 levels were not different between treatment groups; however, il-4 and cytokine-induced neutrophil chemoattractant 1 (cinc-1) levels decreased in the cfx group. |
2015-08-21 |
2023-08-13 |
Not clear |
| Tatiana Barichello, Joao Carlos Nepomuceno Goncalves, Jaqueline da Silva Generoso, Lutiana Roque Simoes, Michael Hikaru Tashiro, Jessica de Assis Goularte, Francieli Vuolo, David Henrique Rodrigues, Marcia Carvalho Vilela, Fabricia Petronilho, Antonio Lucio Teixeira, Joao Queved. Protection of blood brain barrier integrity and modulation of inflammatory mediators during treatment of pneumococcal meningitis with daptomycin or ceftriaxone. Current neurovascular research. vol 11. issue 3. 2015-08-21. PMID:24845856. |
tnf-α, il-6, il-10, cinc-1 and bdnf levels were not different between treatment groups in the hippocampus; however, il-4 levels decreased in cfx group. |
2015-08-21 |
2023-08-13 |
Not clear |
| Jinwook Kim, Miyoung Yang, Juhwan Kim, Lina Song, Sueun Lee, Yeonghoon Son, Sohi Kang, Chun-Sik Bae, Jong-Choon Kim, Sung-Ho Kim, Taekyun Shin, Hongbing Wang, Changjong Moo. Developmental and degenerative modulation of brain-derived neurotrophic factor transcript variants in the mouse hippocampus. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 38. 2015-08-21. PMID:25124374. |
however, little is known about the regulation of bdnf transcript variants in the hippocampus during postnatal development and following chemically induced neurotoxicity. |
2015-08-21 |
2023-08-13 |
mouse |
| Jinwook Kim, Miyoung Yang, Juhwan Kim, Lina Song, Sueun Lee, Yeonghoon Son, Sohi Kang, Chun-Sik Bae, Jong-Choon Kim, Sung-Ho Kim, Taekyun Shin, Hongbing Wang, Changjong Moo. Developmental and degenerative modulation of brain-derived neurotrophic factor transcript variants in the mouse hippocampus. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 38. 2015-08-21. PMID:25124374. |
in the present study, we examined the expression of individual bdnf transcript variants in the mouse hippocampus on postnatal day (pd) 3, 7, 14, 21, and 56, as well as in the adult hippocampus 1, 2, 4, and 8 days after trimethyltin (tmt) treatment. |
2015-08-21 |
2023-08-13 |
mouse |
| Jinwook Kim, Miyoung Yang, Juhwan Kim, Lina Song, Sueun Lee, Yeonghoon Son, Sohi Kang, Chun-Sik Bae, Jong-Choon Kim, Sung-Ho Kim, Taekyun Shin, Hongbing Wang, Changjong Moo. Developmental and degenerative modulation of brain-derived neurotrophic factor transcript variants in the mouse hippocampus. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 38. 2015-08-21. PMID:25124374. |
during postnatal development, the expression levels of common bdnf-coding transcripts and bdnf transcript variants increased gradually in the hippocampus, but the temporal patterns of each exon transcript showed significant differences. |
2015-08-21 |
2023-08-13 |
mouse |
| Andressa Souza, Jairo Alberto Dussan-Sarria, Liciane Fernandes Medeiros, Ana Cláudia Souza, Carla Oliveira, Vanessa Leal Scarabelot, Lauren Naomi Adachi, Elisa Cristiana Winkelmann-Duarte, Bárbara Beatriz Philippi-Martins, Carlos Alexandre Netto, Wolnei Caumo, Iraci L S Torre. Neonatal hypoxic-ischemic encephalopathy reduces c-Fos activation in the rat hippocampus: evidence of a long-lasting effect. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 38. 2015-08-21. PMID:25262910. |
neuronal activity (c-fos activation at region ca1 and dentate gyrus of the hippocampus), nociceptive behavior (von frey, tail-flick, and hot-plate tests), neuroplasticity mediators (bdnf, tnf), and a cellular injury marker (lactase dehydrogenase [ldh]) were assessed in blood serum 14, 30, and 60 days after birth. |
2015-08-21 |
2023-08-13 |
rat |
| Asieh Etemad, Farzam Sheikhzadeh, Naser Ahmadi As. Evaluation of brain-derived neurotrophic factor in diabetic rats. Neurological research. vol 37. issue 3. 2015-08-20. PMID:25082546. |
the purpose of this study was to examine the effect of short- and long-term moderate forced exercise on bdnf levels in the hippocampus of type 1 diabetic rats. |
2015-08-20 |
2023-08-13 |
rat |
| Gelson M Rodrigues, Leandro V Toffoli, Marcelo H Manfredo, José Francis-Oliveira, Andrey S Silva, Hiviny A Raquel, Marli C Martins-Pinge, Estefânia G Moreira, Karen B Fernandes, Gislaine G Pelosi, Marcus V Gome. Acute stress affects the global DNA methylation profile in rat brain: modulation by physical exercise. Behavioural brain research. vol 279. 2015-08-20. PMID:25449846. |
thus, we used the rat model of acute restraint stress (ars) to evaluate the impact of stress on the global dna methylation and on the expression of the dnmt1 and bdnf genes of hippocampus, cortex, hypothalamus and periaqueductal gray (pag). |
2015-08-20 |
2023-08-13 |
rat |
| Gelson M Rodrigues, Leandro V Toffoli, Marcelo H Manfredo, José Francis-Oliveira, Andrey S Silva, Hiviny A Raquel, Marli C Martins-Pinge, Estefânia G Moreira, Karen B Fernandes, Gislaine G Pelosi, Marcus V Gome. Acute stress affects the global DNA methylation profile in rat brain: modulation by physical exercise. Behavioural brain research. vol 279. 2015-08-20. PMID:25449846. |
ars induced a decrease in global dna methylation in hippocampus, cortex and pag of sedentary animals and an increased expression of bdnf in pag. |
2015-08-20 |
2023-08-13 |
rat |
| Liang Wang, Xingya Chang, Liang She, Duo Xu, Wei Huang, Mu-ming Po. Autocrine action of BDNF on dendrite development of adult-born hippocampal neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 22. 2015-08-19. PMID:26041908. |
autocrine action of bdnf on dendrite development of adult-born hippocampal neurons. |
2015-08-19 |
2023-08-13 |
mouse |
| S Helene Richter, Eva Wollmann, Michaela Schmidt, Uwe Zillmann, Rainer Hellweg, Rolf Sprengel, Peter Gas. The effects of neonatal cryoanaesthesia-induced hypothermia on adult emotional behaviour and stress markers in C57BL/6 mice. Behavioural brain research. vol 270. 2015-08-14. PMID:24814613. |
at the age of about 145 days mice were decapitated to record bdnf levels in the hippocampus and serum corticosterone. |
2015-08-14 |
2023-08-13 |
mouse |
| S Helene Richter, Eva Wollmann, Michaela Schmidt, Uwe Zillmann, Rainer Hellweg, Rolf Sprengel, Peter Gas. The effects of neonatal cryoanaesthesia-induced hypothermia on adult emotional behaviour and stress markers in C57BL/6 mice. Behavioural brain research. vol 270. 2015-08-14. PMID:24814613. |
subtle alterations in anxiety-like behaviour, however, were not accompanied by physiological changes in serum corticosterone and hippocampal bdnf levels, arguing against an overall long-lasting effect of neonatal hypothermia on the emotional profile of adult mice. |
2015-08-14 |
2023-08-13 |
mouse |
| David D Ward, Mathew J Summers, Nichole L Saunders, Pierce Janssen, Kimberley E Stuart, James C Vicker. APOE and BDNF Val66Met polymorphisms combine to influence episodic memory function in older adults. Behavioural brain research. vol 271. 2015-08-14. PMID:24946073. |
similarly, although bdnf val66met polymorphisms affect hippocampal morphology and function, associations with learning and/or memory have not always been found. |
2015-08-14 |
2023-08-13 |
human |
| Christian Montag, Andrea Felten, Sebastian Markett, Luise Fischer, Katja Winkel, Andrew Cooper, Martin Reute. The role of the BDNF Val66Met polymorphism in individual differences in long-term memory capacity. Journal of molecular neuroscience : MN. vol 54. issue 4. 2015-08-14. PMID:25267504. |
the protein brain-derived neurotrophic factor (bdnf) plays an important role in diverse memory processes and is strongly expressed in the hippocampus. |
2015-08-14 |
2023-08-13 |
Not clear |
| Allan C Calsavara, Frederico M Soriani, Leda Q Vieira, Priscila A Costa, Milene A Rachid, Antônio L Teixeir. Erratum to: TNFR1 absence protects against memory deficit induced by sepsis possibly through over-expression of hippocampal BDNF. Metabolic brain disease. vol 30. issue 3. 2015-08-14. PMID:25280509. |
erratum to: tnfr1 absence protects against memory deficit induced by sepsis possibly through over-expression of hippocampal bdnf. |
2015-08-14 |
2023-08-13 |
Not clear |