| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Patricia J Allen, Joseph F DeBold, Maribel Rios, Robin B Kanare. Chronic high-dose creatine has opposing effects on depression-related gene expression and behavior in intact and sex hormone-treated gonadectomized male and female rats. Pharmacology, biochemistry, and behavior. vol 130. 2015-12-23. PMID:25560941. |
relative to non-supplemented shams, all hippocampal plasticity-related mrnas measured, including brain-derived neurotrophic factor (bdnf), tyrosine kinase b, doublecortin, calretinin, and calbindin, were downregulated in sham males given 4% creatine, and bdnf, doublecortin, and calbindin mrnas were downregulated in sham females given 4% creatine. |
2015-12-23 |
2023-08-13 |
rat |
| Daniela de Sá-Calçada, Susana Roque, Carlos Branco, Susana Monteiro, Bruno Cerqueira-Rodrigues, Nuno Sousa, Joana A Palha, Margarida Correia-Neve. Exploring Female Mice Interstrain Differences Relevant for Models of Depression. Frontiers in behavioral neuroscience. vol 9. 2015-12-23. PMID:26696854. |
furthermore, c57bl/6 mice display the highest rate of proliferating cells and brain-derived neurotrophic factor (bdnf) expression levels in the hippocampus, while hippocampal dentate granular neurons of balb/c mice show smaller dendritic lengths and fewer ramifications. |
2015-12-23 |
2023-08-13 |
mouse |
| Fabian D Liechti, Nicolas Stüdle, Regula Theurillat, Denis Grandgirard, Wolfgang Thormann, Stephen L Lei. The mood-stabilizer lithium prevents hippocampal apoptosis and improves spatial memory in experimental meningitis. PloS one. vol 9. issue 11. 2015-12-22. PMID:25409333. |
hippocampal gene expression of bcl-2, bax, p53, and bdnf was analyzed. |
2015-12-22 |
2023-08-13 |
rat |
| Penghui Wei, Qingshen Liu, Dong Li, Qiang Zheng, Jinfeng Zhou, Jianjun L. Acute nicotine treatment attenuates lipopolysaccharide-induced cognitive dysfunction by increasing BDNF expression and inhibiting neuroinflammation in the rat hippocampus. Neuroscience letters. vol 604. 2015-12-21. PMID:26259694. |
acute nicotine treatment attenuates lipopolysaccharide-induced cognitive dysfunction by increasing bdnf expression and inhibiting neuroinflammation in the rat hippocampus. |
2015-12-21 |
2023-08-13 |
rat |
| Penghui Wei, Qingshen Liu, Dong Li, Qiang Zheng, Jinfeng Zhou, Jianjun L. Acute nicotine treatment attenuates lipopolysaccharide-induced cognitive dysfunction by increasing BDNF expression and inhibiting neuroinflammation in the rat hippocampus. Neuroscience letters. vol 604. 2015-12-21. PMID:26259694. |
furthermore, nicotine administration led to a significant increase in bdnf mrna expression at 4 and 24h and in bdnf protein expression at 24h after lps injection in the dorsal hippocampus. |
2015-12-21 |
2023-08-13 |
rat |
| Penghui Wei, Qingshen Liu, Dong Li, Qiang Zheng, Jinfeng Zhou, Jianjun L. Acute nicotine treatment attenuates lipopolysaccharide-induced cognitive dysfunction by increasing BDNF expression and inhibiting neuroinflammation in the rat hippocampus. Neuroscience letters. vol 604. 2015-12-21. PMID:26259694. |
taken together, acute nicotine administration attenuated lps-induced cognitive dysfunction, and this neuroprotective effect may be related to the up-regulation of bdnf and the inhibition of neuroinflammation and apoptosis-related proteins in the dorsal hippocampus. |
2015-12-21 |
2023-08-13 |
rat |
| G Zhu, Y Wang, J Li, J Wan. Chronic treatment with ginsenoside Rg1 promotes memory and hippocampal long-term potentiation in middle-aged mice. Neuroscience. vol 292. 2015-12-16. PMID:25724866. |
in addition, ginsenoside rg1 administration up-regulated the expression of hippocampal p-akt, brain-derived neurotrophic factor (bdnf), probdnf and glutamate receptor 1 (glur1), but not p-erk. |
2015-12-16 |
2023-08-13 |
mouse |
| Marion Rodier, Anne Prigent-Tessier, Yannick Béjot, Agnès Jacquin, Claude Mossiat, Christine Marie, Philippe Garnie. Exogenous t-PA administration increases hippocampal mature BDNF levels. plasmin- or NMDA-dependent mechanism? PloS one. vol 9. issue 3. 2015-12-15. PMID:24670989. |
exogenous t-pa administration increases hippocampal mature bdnf levels. |
2015-12-15 |
2023-08-12 |
rat |
| Marion Rodier, Anne Prigent-Tessier, Yannick Béjot, Agnès Jacquin, Claude Mossiat, Christine Marie, Philippe Garnie. Exogenous t-PA administration increases hippocampal mature BDNF levels. plasmin- or NMDA-dependent mechanism? PloS one. vol 9. issue 3. 2015-12-15. PMID:24670989. |
in the hippocampus, we found that rt-pa (10 mg/kg) administration induced a progressive increase in mature bdnf levels associated with trkb activation. |
2015-12-15 |
2023-08-12 |
rat |
| Marion Rodier, Anne Prigent-Tessier, Yannick Béjot, Agnès Jacquin, Claude Mossiat, Christine Marie, Philippe Garnie. Exogenous t-PA administration increases hippocampal mature BDNF levels. plasmin- or NMDA-dependent mechanism? PloS one. vol 9. issue 3. 2015-12-15. PMID:24670989. |
our results showed that despite a rise in rt-pa activity, rt-pa administration failed to increase hippocampal plasmin activity suggesting that the plasminogen/plasmin system is not involved whereas mk801 abrogated the augmentation in mature bdnf levels observed after rt-pa administration. |
2015-12-15 |
2023-08-12 |
rat |
| Marion Rodier, Anne Prigent-Tessier, Yannick Béjot, Agnès Jacquin, Claude Mossiat, Christine Marie, Philippe Garnie. Exogenous t-PA administration increases hippocampal mature BDNF levels. plasmin- or NMDA-dependent mechanism? PloS one. vol 9. issue 3. 2015-12-15. PMID:24670989. |
all together, our results show that rt-pa administration induces increase in hippocampal mature bdnf expression and suggests that rt-pa contributes to the control of brain bdnf synthesis through a plasmin-independent potentiation of nmda receptors signaling. |
2015-12-15 |
2023-08-12 |
rat |
| Y Xing, J Hou, Q Meng, M Yang, H Kurihara, J Tia. Novel antidepressant candidate RO-05 modulated glucocorticoid receptors activation and FKBP5 expression in chronic mild stress model in rats. Neuroscience. vol 290. 2015-12-15. PMID:25644419. |
ro-05 also elevated the expression of bdnf (brain-derived neurotrophic factor) in cms rat hippocampus. |
2015-12-15 |
2023-08-13 |
mouse |
| Chang Shu, Ling Xiao, Jihua Tang, Gaohua Wang, Xueping Zhang, Xiaoping Wan. Blunted behavioral and molecular responses to chronic mild stress in adult rats with experience of infancy maternal separation. The Tohoku journal of experimental medicine. vol 235. issue 2. 2015-12-14. PMID:25742865. |
we therefore investigated the long-term effects of early life adversity on the depression-related behavior and the expression of bdnf and creb in the hippocampus. |
2015-12-14 |
2023-08-13 |
rat |
| Chang Shu, Ling Xiao, Jihua Tang, Gaohua Wang, Xueping Zhang, Xiaoping Wan. Blunted behavioral and molecular responses to chronic mild stress in adult rats with experience of infancy maternal separation. The Tohoku journal of experimental medicine. vol 235. issue 2. 2015-12-14. PMID:25742865. |
sucrose preference and spontaneous activity in the open field test were recorded, and the expression of bdnf and creb in the hippocampus was measured by real-time rt-pcr and western blot analyses. |
2015-12-14 |
2023-08-13 |
rat |
| Chang Shu, Ling Xiao, Jihua Tang, Gaohua Wang, Xueping Zhang, Xiaoping Wan. Blunted behavioral and molecular responses to chronic mild stress in adult rats with experience of infancy maternal separation. The Tohoku journal of experimental medicine. vol 235. issue 2. 2015-12-14. PMID:25742865. |
before exposure to cms, the rats with maternal separation showed the significant decreases in sucrose preference, spontaneous activity, and hippocampal expression of bdnf and creb, compared to the animals without maternal separation. |
2015-12-14 |
2023-08-13 |
rat |
| Chang Shu, Ling Xiao, Jihua Tang, Gaohua Wang, Xueping Zhang, Xiaoping Wan. Blunted behavioral and molecular responses to chronic mild stress in adult rats with experience of infancy maternal separation. The Tohoku journal of experimental medicine. vol 235. issue 2. 2015-12-14. PMID:25742865. |
thus, early life adversity leads to long-term decreases in the capacity of enjoying sweetness, spontaneous activity, and hippocampal expression of bdnf and creb. |
2015-12-14 |
2023-08-13 |
rat |
| Paola Caporali, Debora Cutuli, Francesca Gelfo, Daniela Laricchiuta, Francesca Foti, Paola De Bartolo, Francesco Angelucci, Laura Petrosin. Interaction does Count: A Cross-Fostering Study on Transgenerational Effects of Pre-reproductive Maternal Enrichment. Frontiers in behavioral neuroscience. vol 9. 2015-12-09. PMID:26648854. |
moreover, the expression of brain-derived-neurotrophic-factor (bdnf) was evaluated in the hippocampus and frontal cortex of dams and pups at weaning. |
2015-12-09 |
2023-08-13 |
rat |
| Paola Caporali, Debora Cutuli, Francesca Gelfo, Daniela Laricchiuta, Francesca Foti, Paola De Bartolo, Francesco Angelucci, Laura Petrosin. Interaction does Count: A Cross-Fostering Study on Transgenerational Effects of Pre-reproductive Maternal Enrichment. Frontiers in behavioral neuroscience. vol 9. 2015-12-09. PMID:26648854. |
nevertheless, pre-reproductive maternal enrichment kept influencing neurotrophic pattern, with enriched dams expressing increased frontal bdnf levels (regardless of the kind of fostered pups), and their offspring expressing increased hippocampal bdnf levels. |
2015-12-09 |
2023-08-13 |
rat |
| Lauren Naomi Spezia Adachi, Alexandre Silva Quevedo, Andressa de Souza, Vanessa Leal Scarabelot, Joanna Ripoll Rozisky, Carla de Oliveira, Paulo Ricardo Marques Filho, Liciane Fernandes Medeiros, Felipe Fregni, Wolnei Caumo, Iraci L S Torre. Exogenously induced brain activation regulates neuronal activity by top-down modulation: conceptualized model for electrical brain stimulation. Experimental brain research. vol 233. issue 5. 2015-12-08. PMID:25665871. |
bdnf levels were used to assess neuronal activity at spinal cord, brainstem, and hippocampus. |
2015-12-08 |
2023-08-13 |
rat |
| Yuxue Jiang, Jinfu Zh. Effects of sleep deprivation on behaviors and abnormal hippocampal BDNF/miR-10B expression in rats with chronic stress depression. International journal of clinical and experimental pathology. vol 8. issue 1. 2015-12-08. PMID:25755749. |
these results indicate that sleep deprivation is closely linked with the downregulation of mir-10b and possibly the upregulation of bdnf in the hippocampus in the cups rats. |
2015-12-08 |
2023-08-13 |
rat |