| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yeonghoon Son, Miyoung Yang, Sohi Kang, Sueun Lee, Jinwook Kim, Juhwan Kim, Seri Park, Joong-Sun Kim, Sung-Kee Jo, Uhee Jung, Taekyun Shin, Sung-Ho Kim, Hongbing Wang, Changjong Moo. Cranial irradiation regulates CREB-BDNF signaling and variant BDNF transcript levels in the mouse hippocampus. Neurobiology of learning and memory. vol 121. 2016-01-22. PMID:25792232. |
in the hippocampus, brain-derived neurotrophic factor (bdnf) plays roles in neurogenesis, neuronal survival, neuronal differentiation, and synaptic plasticity. |
2016-01-22 |
2023-08-13 |
mouse |
| Yeonghoon Son, Miyoung Yang, Sohi Kang, Sueun Lee, Jinwook Kim, Juhwan Kim, Seri Park, Joong-Sun Kim, Sung-Kee Jo, Uhee Jung, Taekyun Shin, Sung-Ho Kim, Hongbing Wang, Changjong Moo. Cranial irradiation regulates CREB-BDNF signaling and variant BDNF transcript levels in the mouse hippocampus. Neurobiology of learning and memory. vol 121. 2016-01-22. PMID:25792232. |
furthermore, changes in the levels of bdnf, the camp-response element binding protein (creb) phosphorylation, and bdnf transcript variants were measured in the hippocampus 1 month after cranial irradiation. |
2016-01-22 |
2023-08-13 |
mouse |
| Yeonghoon Son, Miyoung Yang, Sohi Kang, Sueun Lee, Jinwook Kim, Juhwan Kim, Seri Park, Joong-Sun Kim, Sung-Kee Jo, Uhee Jung, Taekyun Shin, Sung-Ho Kim, Hongbing Wang, Changjong Moo. Cranial irradiation regulates CREB-BDNF signaling and variant BDNF transcript levels in the mouse hippocampus. Neurobiology of learning and memory. vol 121. 2016-01-22. PMID:25792232. |
both phosphorylated creb and bdnf protein levels were significantly downregulated after irradiation of the hippocampus. |
2016-01-22 |
2023-08-13 |
mouse |
| Yeonghoon Son, Miyoung Yang, Sohi Kang, Sueun Lee, Jinwook Kim, Juhwan Kim, Seri Park, Joong-Sun Kim, Sung-Kee Jo, Uhee Jung, Taekyun Shin, Sung-Ho Kim, Hongbing Wang, Changjong Moo. Cranial irradiation regulates CREB-BDNF signaling and variant BDNF transcript levels in the mouse hippocampus. Neurobiology of learning and memory. vol 121. 2016-01-22. PMID:25792232. |
the reductions in creb phosphorylation and bdnf expression induced by differential regulation of bdnf hippocampal exon transcripts may be associated with the memory deficits evident in mice after cranial irradiation. |
2016-01-22 |
2023-08-13 |
mouse |
| Urszula Doboszewska, Bernadeta Szewczyk, Magdalena Sowa-Kućma, Katarzyna Młyniec, Anna Rafało, Beata Ostachowicz, Marek Lankosz, Gabriel Nowa. Antidepressant activity of fluoxetine in the zinc deficiency model in rats involves the NMDA receptor complex. Behavioural brain research. vol 287. 2016-01-20. PMID:25845739. |
the proteins of nmdar (glun1, glun2a and glun2b) or ampar (glua1) subunits, p-creb and bdnf in the hippocampus (western blot) and serum zinc level (txrf) were examined. |
2016-01-20 |
2023-08-13 |
rat |
| Urszula Doboszewska, Bernadeta Szewczyk, Magdalena Sowa-Kućma, Katarzyna Młyniec, Anna Rafało, Beata Ostachowicz, Marek Lankosz, Gabriel Nowa. Antidepressant activity of fluoxetine in the zinc deficiency model in rats involves the NMDA receptor complex. Behavioural brain research. vol 287. 2016-01-20. PMID:25845739. |
administration of flx counteracted the zinc restriction-induced changes in serum zinc level and hippocampal glun1, glun2a, glun2b and p-creb but not bdnf or ps845-glua1 protein levels. |
2016-01-20 |
2023-08-13 |
rat |
| R D Moloney, T G Dinan, J F Crya. Strain-dependent variations in visceral sensitivity: relationship to stress, anxiety and spinal glutamate transporter expression. Genes, brain, and behavior. vol 14. issue 4. 2016-01-18. PMID:25851919. |
mrna expression levels of eaat-1, bdnf and 5ht1a receptor (htr1a) were quantified in the lumbosacral spinal cord, amygdala and hippocampus. |
2016-01-18 |
2023-08-13 |
mouse |
| R D Moloney, T G Dinan, J F Crya. Strain-dependent variations in visceral sensitivity: relationship to stress, anxiety and spinal glutamate transporter expression. Genes, brain, and behavior. vol 14. issue 4. 2016-01-18. PMID:25851919. |
cba/j mice consistently exhibited heightened visceral sensitivity, anxiety behaviour and depression-like behaviour which were associated with decreased spinal eaat-1 and hippocampal bdnf and htr1a. |
2016-01-18 |
2023-08-13 |
mouse |
| Semil Selcen Gocmez, Yusufhan Yazir, Deniz Sahin, Sabriye Karadenizli, Tijen Utka. The effect of a selective neuronal nitric oxide synthase inhibitor 3-bromo 7-nitroindazole on spatial learning and memory in rats. Pharmacology, biochemistry, and behavior. vol 131. 2016-01-15. PMID:25636602. |
the mwm training was associated with a significant increase in the brain-derived neurotrophic factor (bdnf) mrna expression in the hippocampus. |
2016-01-15 |
2023-08-13 |
human |
| Semil Selcen Gocmez, Yusufhan Yazir, Deniz Sahin, Sabriye Karadenizli, Tijen Utka. The effect of a selective neuronal nitric oxide synthase inhibitor 3-bromo 7-nitroindazole on spatial learning and memory in rats. Pharmacology, biochemistry, and behavior. vol 131. 2016-01-15. PMID:25636602. |
bdnf mrna expression in the hippocampus did not change after 3-br 7-ni treatment. |
2016-01-15 |
2023-08-13 |
human |
| Jia-Mei Jiang, Cheng-Fang Zhou, Sheng-Lan Gao, Ying Tian, Chun-Yan Wang, Li Wang, Hong-Feng Gu, Xiao-Qing Tan. BDNF-TrkB pathway mediates neuroprotection of hydrogen sulfide against formaldehyde-induced toxicity to PC12 cells. PloS one. vol 10. issue 3. 2016-01-15. PMID:25749582. |
intriguingly, our previous data have illustrated the upregulatory role of h2s on bdnf protein expression in the hippocampus of rats. |
2016-01-15 |
2023-08-13 |
rat |
| Rose Mary Carvalho Pinheiro, Maria Noêmia Martins de Lima, Bernardo Chaves Dávila Portal, Stefano Boemler Busato, Lucio Falavigna, Rafael Dal Ponte Ferreira, André Contri Paz, Bianca Wollenhaupt de Aguiar, Flávio Kapczinski, Nadja Schröde. Long-lasting recognition memory impairment and alterations in brain levels of cytokines and BDNF induced by maternal deprivation: effects of valproic acid and topiramate. Journal of neural transmission (Vienna, Austria : 1996). vol 122. issue 5. 2016-01-13. PMID:25182413. |
maternal deprivation, commonly used as a source of neonatal stress, impairs memory in adult rats and reduces hippocampal brain-derived neurotrophic factor (bdnf) levels. |
2016-01-13 |
2023-08-13 |
rat |
| Rose Mary Carvalho Pinheiro, Maria Noêmia Martins de Lima, Bernardo Chaves Dávila Portal, Stefano Boemler Busato, Lucio Falavigna, Rafael Dal Ponte Ferreira, André Contri Paz, Bianca Wollenhaupt de Aguiar, Flávio Kapczinski, Nadja Schröde. Long-lasting recognition memory impairment and alterations in brain levels of cytokines and BDNF induced by maternal deprivation: effects of valproic acid and topiramate. Journal of neural transmission (Vienna, Austria : 1996). vol 122. issue 5. 2016-01-13. PMID:25182413. |
the aim of the present study was to investigate the effects of maternal separation on the levels of il-10 and tnf-α, and bdnf in the hippocampus and prefrontal cortex of adult rats. |
2016-01-13 |
2023-08-13 |
rat |
| Rose Mary Carvalho Pinheiro, Maria Noêmia Martins de Lima, Bernardo Chaves Dávila Portal, Stefano Boemler Busato, Lucio Falavigna, Rafael Dal Ponte Ferreira, André Contri Paz, Bianca Wollenhaupt de Aguiar, Flávio Kapczinski, Nadja Schröde. Long-lasting recognition memory impairment and alterations in brain levels of cytokines and BDNF induced by maternal deprivation: effects of valproic acid and topiramate. Journal of neural transmission (Vienna, Austria : 1996). vol 122. issue 5. 2016-01-13. PMID:25182413. |
the results indicated that, in addition to inducing memory deficits, maternal deprivation increased the levels of il-10 in the hippocampus, and tnf-α in the hippocampus and in the cortex, and decreased hippocampal levels of bdnf, in adult life. |
2016-01-13 |
2023-08-13 |
rat |
| Tatiana Barichello, Jaqueline S Generoso, Lutiana R Simões, Amanda V Steckert, Ana Paula Moreira, Diogo Dominguini, Pâmela Ferrari, Carolina Gubert, Flávio Kapczinski, Luciano K Jornada, Lucineia G Danielski, Fabricia Petronilho, Josiane Budni, João Queved. Folic acid prevented cognitive impairment in experimental pneumococcal meningitis. Journal of neural transmission (Vienna, Austria : 1996). vol 122. issue 5. 2016-01-13. PMID:25233798. |
in the hippocampus, bdnf expression decreased in the meningitis group; however, adjuvant treatment with 10 mg of folic acid increased bdnf expression, decreased lipid peroxidation, protein carbonylation, nitrate/nitrite levels, and myeloperoxidase activity and increased superoxide dismutase activity. |
2016-01-13 |
2023-08-13 |
Not clear |
| Fabíola Trevizol, Verônica T Dias, Katiane Roversi, Raquel C S Barcelos, Fábio T Kuhn, Karine Roversi, Camila S Pase, Ronaldo Golombieski, Juliana C Veit, Jaqueline Piccolo, Tatiana Emanuelli, João B T Rocha, Marilise E Bürge. Cross-generational trans fat intake modifies BDNF mRNA in the hippocampus: Impact on memory loss in a mania animal model. Hippocampus. vol 25. issue 5. 2016-01-13. PMID:25394793. |
cross-generational trans fat intake modifies bdnf mrna in the hippocampus: impact on memory loss in a mania animal model. |
2016-01-13 |
2023-08-13 |
rat |
| Fabíola Trevizol, Verônica T Dias, Katiane Roversi, Raquel C S Barcelos, Fábio T Kuhn, Karine Roversi, Camila S Pase, Ronaldo Golombieski, Juliana C Veit, Jaqueline Piccolo, Tatiana Emanuelli, João B T Rocha, Marilise E Bürge. Cross-generational trans fat intake modifies BDNF mRNA in the hippocampus: Impact on memory loss in a mania animal model. Hippocampus. vol 25. issue 5. 2016-01-13. PMID:25394793. |
our findings confirm that provision of n-3 or tfa during development over two generations is able to change the neuronal membrane lipid composition, protecting or impairing the hippocampus, respectively, thus affecting neurothrophic factor expression such as bdnf mrna. |
2016-01-13 |
2023-08-13 |
rat |
| Andrew C Venezia, Lisa M Guth, Espen E Spangenburg, Stephen M Rot. Lifelong parental voluntary wheel running increases offspring hippocampal Pgc-1α mRNA expression but not mitochondrial content or Bdnf expression. Neuroreport. vol 26. issue 8. 2016-01-13. PMID:25919993. |
lifelong parental voluntary wheel running increases offspring hippocampal pgc-1α mrna expression but not mitochondrial content or bdnf expression. |
2016-01-13 |
2023-08-13 |
mouse |
| Andrew C Venezia, Lisa M Guth, Espen E Spangenburg, Stephen M Rot. Lifelong parental voluntary wheel running increases offspring hippocampal Pgc-1α mRNA expression but not mitochondrial content or Bdnf expression. Neuroreport. vol 26. issue 8. 2016-01-13. PMID:25919993. |
when exercise is initiated during pregnancy, offspring of physically active mothers have higher hippocampal expression of brain-derived neurotrophic factor (bdnf) and other plasticity-associated and mitochondria-associated genes, resulting in hippocampal structural and functional adaptations. |
2016-01-13 |
2023-08-13 |
mouse |
| Katherine M Allen, Tertia D Purves-Tyson, Samantha J Fung, Cynthia Shannon Weicker. The effect of adolescent testosterone on hippocampal BDNF and TrkB mRNA expression: relationship with cell proliferation. BMC neuroscience. vol 16. 2016-01-12. PMID:25886766. |
the effect of adolescent testosterone on hippocampal bdnf and trkb mrna expression: relationship with cell proliferation. |
2016-01-12 |
2023-08-13 |
rat |