| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Abeer E Dief, Doaa M Samy, Fatma I Doweda. Impact of exercise and vitamin B1 intake on hippocampal brain-derived neurotrophic factor and spatial memory performance in a rat model of stress. Journal of nutritional science and vitaminology. vol 61. issue 1. 2016-02-08. PMID:25994133. |
chronic immobilization stress resulted in a significant decrease in bdnf and ach levels in the hippocampus and impairment in spatial memory functions and decreased basal activity. |
2016-02-08 |
2023-08-13 |
rat |
| Chih-Chung Chen, Chi-Jen Chen, Dean Wu, Nai-Fang Chi, Po-Chih Chen, Yen-Peng Liao, Hung-Wen Chiu, Chaur-Jong H. BDNF Val66Met Polymorphism on Functional MRI During n-Back Working Memory Tasks. Medicine. vol 94. issue 42. 2016-02-08. PMID:26496261. |
val66met polymorphism on the brain-derived neurotrophic factor (bdnf) gene is associated with hippocampal pathology and impaired episodic memory. |
2016-02-08 |
2023-08-13 |
human |
| Rui Ji, Lingbin Meng, Xin Jiang, Naresh Kumar Cvm, Jixiang Ding, Qiutang Li, Qingxian L. TAM receptors support neural stem cell survival, proliferation and neuronal differentiation. PloS one. vol 9. issue 12. 2016-02-04. PMID:25514676. |
to elucidate the underlying mechanism that the tam receptors play on the differentiating nscs, we examined the expression profile of neurotrophins and their receptors by real-time qpcr on the total rnas from hippocampus and primary nscs; and found that the tko nsc showed a significant reduction in the expression of both nerve growth factor (ngf) and brain-derived neurotrophic factor (bdnf), but accompanied by compensational increases in the expression of the trka, trkb, trkc and p75 receptors. |
2016-02-04 |
2023-08-13 |
Not clear |
| Jay R Hoffman, Ishay Ostfeld, Jeffrey R Stout, Roger C Harris, Zeev Kaplan, Hagit Cohe. β-Alanine supplemented diets enhance behavioral resilience to stress exposure in an animal model of PTSD. Amino acids. vol 47. issue 6. 2016-02-04. PMID:25758106. |
bdnf expression in the ca1 and dg subregions of the hippocampus was lower (p < 0.05) in animals exposed and fed a normal diet compared to animals exposed and supplemented with ba, or animals unexposed. |
2016-02-04 |
2023-08-13 |
rat |
| Jay R Hoffman, Ishay Ostfeld, Jeffrey R Stout, Roger C Harris, Zeev Kaplan, Hagit Cohe. β-Alanine supplemented diets enhance behavioral resilience to stress exposure in an animal model of PTSD. Amino acids. vol 47. issue 6. 2016-02-04. PMID:25758106. |
in conclusion, ba supplementation in rats increased brain carnosine concentrations and resulted in a reduction in ptsd-like behavior, which may be mediated in part by maintaining bdnf expression in the hippocampus. |
2016-02-04 |
2023-08-13 |
rat |
| Ekaterina A Rudnitskaya, Kseniya Yi Maksimova, Natalia A Muraleva, Sergey V Logvinov, Lyudmila V Yanshole, Nataliya G Kolosova, Natalia A Stefanov. Beneficial effects of melatonin in a rat model of sporadic Alzheimer's disease. Biogerontology. vol 16. issue 3. 2016-02-03. PMID:25515660. |
the results showed that melatonin treatment restored melatonin secretion in the pineal gland of oxys rats as well as the serum levels of growth hormone and igf-1, the level of bdnf in the hippocampus and the healthy state of hippocampal neurons. |
2016-02-03 |
2023-08-13 |
rat |
| Xue-Feng Yu, Xue-Feng Yu, Xu-Pei Xie, Jian-Chun Pa. [Effect of fluoxetine on the expressions of BDNF and Bcl-2 during fear memory formation]. Yao xue xue bao = Acta pharmaceutica Sinica. vol 49. issue 4. 2016-02-02. PMID:24974462. |
the aim of this study is to investigate the effect of fluoxetine (flx) on the expressions of bdnf and bcl-2 in the hippocampus, the amygdala and the prefrontal cortex of conditioned fear (cf) model mice. |
2016-02-02 |
2023-08-13 |
mouse |
| Xue-Feng Yu, Xue-Feng Yu, Xu-Pei Xie, Jian-Chun Pa. [Effect of fluoxetine on the expressions of BDNF and Bcl-2 during fear memory formation]. Yao xue xue bao = Acta pharmaceutica Sinica. vol 49. issue 4. 2016-02-02. PMID:24974462. |
the results showed that the freezing time of flx-pretreated cf group was significantly lower than that of cf group; flx pretreatment up-regulated the expression of bcl-2 in the hippocampus at 1 d after cf stress (p < 0.001), but no significant differences was observed at 7 d; bdnf significantly increased in the hippocampus at 7 d (p < 0.001), but no differences at 1 d; the expressions of bdnf and bcl-2 in the amygdala and the prefrontal cortex were of no obvious differences between cf group and flx-pretreated cf group at 1 d or 7 d after cf stress. |
2016-02-02 |
2023-08-13 |
mouse |
| Xue-Feng Yu, Xue-Feng Yu, Xu-Pei Xie, Jian-Chun Pa. [Effect of fluoxetine on the expressions of BDNF and Bcl-2 during fear memory formation]. Yao xue xue bao = Acta pharmaceutica Sinica. vol 49. issue 4. 2016-02-02. PMID:24974462. |
furthermore, the results indicated that flx pretreatment could protect against cf stress-induced neurological damage via the activation of bdnf and bcl-2 in hippocampus. |
2016-02-02 |
2023-08-13 |
mouse |
| M J Eimerbrink, J D White, R J Pendry, S L Hodges, L N Sadler, J D Wiles, M K Weintraub, M J Chumley, G W Boeh. Administration of the inverse benzodiazepine agonist MRK-016 rescues acquisition and memory consolidation following peripheral administration of bacterial endotoxin. Behavioural brain research. vol 288. 2016-01-27. PMID:25823763. |
additionally, hippocampal samples were collected 4h after lps injections and immediately after testing, to evaluate brain-derived neurotrophic factor (bdnf) and insulin-like growth factor 1 (igf-1) mrna expression. |
2016-01-27 |
2023-08-13 |
mouse |
| Liu Luo, Xiao-Long Liu, Rong-Hao Mu, Yong-Jing Wu, Bin-Bin Liu, Di Geng, Qing Liu, Li-Tao Y. Hippocampal BDNF signaling restored with chronic asiaticoside treatment in depression-like mice. Brain research bulletin. vol 114. 2016-01-26. PMID:25857945. |
hippocampal bdnf signaling restored with chronic asiaticoside treatment in depression-like mice. |
2016-01-26 |
2023-08-13 |
mouse |
| Liu Luo, Xiao-Long Liu, Rong-Hao Mu, Yong-Jing Wu, Bin-Bin Liu, Di Geng, Qing Liu, Li-Tao Y. Hippocampal BDNF signaling restored with chronic asiaticoside treatment in depression-like mice. Brain research bulletin. vol 114. 2016-01-26. PMID:25857945. |
in addition, we found that asiaticoside up-regulated bdnf, psd-95 and synapsin i expression only in the hippocampus but not in the frontal cortex in both non-stressed and cums mice. |
2016-01-26 |
2023-08-13 |
mouse |
| Liu Luo, Xiao-Long Liu, Rong-Hao Mu, Yong-Jing Wu, Bin-Bin Liu, Di Geng, Qing Liu, Li-Tao Y. Hippocampal BDNF signaling restored with chronic asiaticoside treatment in depression-like mice. Brain research bulletin. vol 114. 2016-01-26. PMID:25857945. |
moreover, the expression of hippocampal bdnf, psd-95 and synapsin i that had increased with asiaticoside also declined with k252a pretreatment. |
2016-01-26 |
2023-08-13 |
mouse |
| Liu Luo, Xiao-Long Liu, Rong-Hao Mu, Yong-Jing Wu, Bin-Bin Liu, Di Geng, Qing Liu, Li-Tao Y. Hippocampal BDNF signaling restored with chronic asiaticoside treatment in depression-like mice. Brain research bulletin. vol 114. 2016-01-26. PMID:25857945. |
in conclusion, our study implies that it is possible that asiaticoside exerts its antidepressant-like action by activating bdnf signaling in the hippocampus. |
2016-01-26 |
2023-08-13 |
mouse |
| Xinjian Zhu, Jingde Dong, Kai Shen, Ying Bai, Yuan Zhang, Xuan Lv, Jie Chao, Honghong Ya. NMDA receptor NR2B subunits contribute to PTZ-kindling-induced hippocampal astrocytosis and oxidative stress. Brain research bulletin. vol 114. 2016-01-26. PMID:25896886. |
additionally, expression of brain-derived neurotrophic factor (bdnf) in the hippocampus was found to be up-regulated in ptz-kindled mice. |
2016-01-26 |
2023-08-13 |
mouse |
| Xinjian Zhu, Jingde Dong, Kai Shen, Ying Bai, Yuan Zhang, Xuan Lv, Jie Chao, Honghong Ya. NMDA receptor NR2B subunits contribute to PTZ-kindling-induced hippocampal astrocytosis and oxidative stress. Brain research bulletin. vol 114. 2016-01-26. PMID:25896886. |
these results indicate that nmda receptor nr2b subunits contribute to epilepsy-associated pathological and biochemical events, including hippocampal astrocytosis, oxidative stress and neuron loss, and these events might be correlated with up-regulation of bdnf expression. |
2016-01-26 |
2023-08-13 |
mouse |
| J J Botterill, K J Brymer, H J Caruncho, L E Kalynchu. Aberrant hippocampal neurogenesis after limbic kindling: Relationship to BDNF and hippocampal-dependent memory. Epilepsy & behavior : E&B. vol 47. 2016-01-25. PMID:25976182. |
aberrant hippocampal neurogenesis after limbic kindling: relationship to bdnf and hippocampal-dependent memory. |
2016-01-25 |
2023-08-13 |
rat |
| J J Botterill, K J Brymer, H J Caruncho, L E Kalynchu. Aberrant hippocampal neurogenesis after limbic kindling: Relationship to BDNF and hippocampal-dependent memory. Epilepsy & behavior : E&B. vol 47. 2016-01-25. PMID:25976182. |
we also quantified hippocampal brain-derived neurotrophin factor (bdnf) protein levels using an elisa kit and assessed memory performance using a hippocampal-dependent fear conditioning paradigm. |
2016-01-25 |
2023-08-13 |
rat |
| J J Botterill, K J Brymer, H J Caruncho, L E Kalynchu. Aberrant hippocampal neurogenesis after limbic kindling: Relationship to BDNF and hippocampal-dependent memory. Epilepsy & behavior : E&B. vol 47. 2016-01-25. PMID:25976182. |
limbic kindling also enhanced bdnf protein levels throughout the entire hippocampus and impaired the retrieval of fear memories. |
2016-01-25 |
2023-08-13 |
rat |
| Yeonghoon Son, Miyoung Yang, Sohi Kang, Sueun Lee, Jinwook Kim, Juhwan Kim, Seri Park, Joong-Sun Kim, Sung-Kee Jo, Uhee Jung, Taekyun Shin, Sung-Ho Kim, Hongbing Wang, Changjong Moo. Cranial irradiation regulates CREB-BDNF signaling and variant BDNF transcript levels in the mouse hippocampus. Neurobiology of learning and memory. vol 121. 2016-01-22. PMID:25792232. |
cranial irradiation regulates creb-bdnf signaling and variant bdnf transcript levels in the mouse hippocampus. |
2016-01-22 |
2023-08-13 |
mouse |