| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yasuhisa Ano, Makiko Ozawa, Toshiko Kutsukake, Shinya Sugiyama, Kazuyuki Uchida, Aruto Yoshida, Hiroyuki Nakayam. Preventive effects of a fermented dairy product against Alzheimer's disease and identification of a novel oleamide with enhanced microglial phagocytosis and anti-inflammatory activity. PloS one. vol 10. issue 3. 2015-12-08. PMID:25760987. |
here, in a mouse model of alzheimer's disease (5xfad), intake of a dairy product fermented with penicillium candidum had preventive effects on the disease by reducing the accumulation of amyloid β (aβ) and hippocampal inflammation (tnf-α and mip-1α production), and enhancing hippocampal neurotrophic factors (bdnf and gdnf). |
2015-12-08 |
2023-08-13 |
mouse |
| Jing-Jing Tong, Gui-Hai Chen, Fang Wang, Xue-Wei Li, Lei Cao, Xu Sui, Fei Tao, Wen-Wen Yan, Zhao-Jun We. Chronic acarbose treatment alleviates age-related behavioral and biochemical changes in SAMP8 mice. Behavioural brain research. vol 284. 2015-12-07. PMID:25698601. |
the results showed that the aged controls exhibited declines in sensorimotor ability, open field anxiety, spatial and non-spatial memory abilities, decreased serum insulin levels, increased igf-1 receptor and synaptotagmin 1 (syt1) levels and decreased insulin receptor, brain-derived neurotrophic factor (bdnf) and syntaxin 1 (stx1) levels in the hippocampal layers. |
2015-12-07 |
2023-08-13 |
mouse |
| Kathlyn J Gan, Michael A Silverma. Dendritic and axonal mechanisms of Ca2+ elevation impair BDNF transport in Aβ oligomer-treated hippocampal neurons. Molecular biology of the cell. vol 26. issue 6. 2015-12-04. PMID:25609087. |
dendritic and axonal mechanisms of ca2+ elevation impair bdnf transport in aβ oligomer-treated hippocampal neurons. |
2015-12-04 |
2023-08-13 |
Not clear |
| Nikolaos P Daskalakis, Edo Ronald De Kloet, Rachel Yehuda, Dolores Malaspina, Thorsten M Kran. Early Life Stress Effects on Glucocorticoid-BDNF Interplay in the Hippocampus. Frontiers in molecular neuroscience. vol 8. 2015-12-04. PMID:26635521. |
the neurotrophin and gc-signaling pathways co-exist throughout the central nervous system (cns), particularly in the hippocampus, which has high expression levels of glucocorticoid-receptors (gr) and mineralocorticoid-receptors (mr) as well as brain-derived neurotrophic factor (bdnf) and its receptor, tropomyosin-related kinase receptor b (trkb). |
2015-12-04 |
2023-08-13 |
Not clear |
| Shih-Jen Tsa. Transcranial focused ultrasound as a possible treatment for major depression. Medical hypotheses. vol 84. issue 4. 2015-12-03. PMID:25665863. |
moreover, increasing brain bdnf and adult hippocampal neurogenesis have been implicated in some of the therapeutic mechanisms of antidepressants. |
2015-12-03 |
2023-08-13 |
mouse |
| Shih-Jen Tsa. Transcranial focused ultrasound as a possible treatment for major depression. Medical hypotheses. vol 84. issue 4. 2015-12-03. PMID:25665863. |
from the above evidence, tfus can increase brain bdnf levels and neurogenesis in the hippocampus, suggesting it could be an alternative strategy for the treatment of mdd. |
2015-12-03 |
2023-08-13 |
mouse |
| Greice Caletti, Felipe Borges Almeida, Grasiela Agnes, Maurício Schüler Nin, Helena Maria Tannhauser Barros, Rosane Gome. Antidepressant dose of taurine increases mRNA expression of GABAA receptor α2 subunit and BDNF in the hippocampus of diabetic rats. Behavioural brain research. vol 283. 2015-12-02. PMID:25612506. |
antidepressant dose of taurine increases mrna expression of gabaa receptor α2 subunit and bdnf in the hippocampus of diabetic rats. |
2015-12-02 |
2023-08-13 |
rat |
| Greice Caletti, Felipe Borges Almeida, Grasiela Agnes, Maurício Schüler Nin, Helena Maria Tannhauser Barros, Rosane Gome. Antidepressant dose of taurine increases mRNA expression of GABAA receptor α2 subunit and BDNF in the hippocampus of diabetic rats. Behavioural brain research. vol 283. 2015-12-02. PMID:25612506. |
later they were euthanized, the brains were weighed, and the hippocampus was dissected for α2 gabaa subunit and bdnf mrna expression. |
2015-12-02 |
2023-08-13 |
rat |
| C B Filho, C R Jesse, F Donato, R Giacomeli, L Del Fabbro, M da Silva Antunes, M G de Gomes, A T R Goes, S P Boeira, M Prigol, L C Souz. Chronic unpredictable mild stress decreases BDNF and NGF levels and Na(+),K(+)-ATPase activity in the hippocampus and prefrontal cortex of mice: antidepressant effect of chrysin. Neuroscience. vol 289. 2015-12-01. PMID:25592430. |
chronic unpredictable mild stress decreases bdnf and ngf levels and na(+),k(+)-atpase activity in the hippocampus and prefrontal cortex of mice: antidepressant effect of chrysin. |
2015-12-01 |
2023-08-13 |
mouse |
| C B Filho, C R Jesse, F Donato, R Giacomeli, L Del Fabbro, M da Silva Antunes, M G de Gomes, A T R Goes, S P Boeira, M Prigol, L C Souz. Chronic unpredictable mild stress decreases BDNF and NGF levels and Na(+),K(+)-ATPase activity in the hippocampus and prefrontal cortex of mice: antidepressant effect of chrysin. Neuroscience. vol 289. 2015-12-01. PMID:25592430. |
thus, we aimed to evaluate the effect of cums on brain-derived neurotropic factor (bdnf) and nerve growth factor (ngf) levels as well as the na(+),k(+)-atpase activity in the hippocampus and prefrontal cortex of female mice. |
2015-12-01 |
2023-08-13 |
mouse |
| Qian Xu, Xue-Fei Ji, Tian-Yan Chi, Peng Liu, Ge Jin, Shao-Li Gu, Li-Bo Zo. Sigma 1 receptor activation regulates brain-derived neurotrophic factor through NR2A-CaMKIV-TORC1 pathway to rescue the impairment of learning and memory induced by brain ischaemia/reperfusion. Psychopharmacology. vol 232. issue 10. 2015-11-27. PMID:25420607. |
the agonist of sig-1r was reported to up-regulate brain-derived neurotrophic factor (bdnf) levels in the hippocampus of mice. |
2015-11-27 |
2023-08-13 |
mouse |
| Jin Young Chung, Dae Young Yoo, Wooseok Im, Jung Hoon Choi, Sun Shin Yi, Hwa Young Youn, In Koo Hwang, Je Kyung Seong, Yeo Sung Yoo. Electroacupuncture at the Zusanli and Baihui acupoints ameliorates type-2 diabetes-induced reductions in proliferating cells and differentiated neuroblasts in the hippocampal dentate gyrus with increasing brain-derived neurotrophic factor levels. The Journal of veterinary medical science. vol 77. issue 2. 2015-11-25. PMID:25342636. |
brain-derived neurotrophic factor (bdnf) levels were significantly decreased in hippocampal homogenates of zdf-sham group compared to those in the zlc group. |
2015-11-25 |
2023-08-13 |
rat |
| A C Campos, F Brant, A S Miranda, F S Machado, A L Teixeir. Cannabidiol increases survival and promotes rescue of cognitive function in a murine model of cerebral malaria. Neuroscience. vol 289. 2015-11-25. PMID:25595981. |
th1/th2 cytokines and neurotrophins (brain-derived neurotrophic factor (bdnf) and nerve growth factor (ngf)) were measured in the prefrontal cortex and hippocampus of experimental groups. |
2015-11-25 |
2023-08-13 |
mouse |
| A C Campos, F Brant, A S Miranda, F S Machado, A L Teixeir. Cannabidiol increases survival and promotes rescue of cognitive function in a murine model of cerebral malaria. Neuroscience. vol 289. 2015-11-25. PMID:25595981. |
cbd treatment resulted in an increase in bdnf expression in the hippocampus and decreased levels of proinflammatory cytokines in the hippocampus (tnf-α) and prefrontal cortex (il-6). |
2015-11-25 |
2023-08-13 |
mouse |
| A D Ivanov, G R Tukhbatova, S V Salozhin, V A Markevic. NGF but not BDNF overexpression protects hippocampal LTP from beta-amyloid-induced impairment. Neuroscience. vol 289. 2015-11-25. PMID:25595986. |
ngf but not bdnf overexpression protects hippocampal ltp from beta-amyloid-induced impairment. |
2015-11-25 |
2023-08-13 |
rat |
| Nastaran Eidelkhani, Maryam Radahmadi, Mohammad Kazemi, Laleh Rafiee, Hojjatallah Alaei, Parham Reis. Effects of doxepin on brain-derived neurotrophic factor, tumor necrosis factor alpha, mitogen-activated protein kinase 14, and AKT1 genes expression in rat hippocampus. Advanced biomedical research. vol 4. 2015-11-25. PMID:26601091. |
therefore, this study investigated the effect of doxepin on gene expression of brain-derived neurotrophic factor (bdnf), tumor necrosis factor alpha (tnf-α), mitogen-activated protein kinase 14 (mapk14), and serine-threonine protein kinase akt1 in rat hippocampus. |
2015-11-25 |
2023-08-13 |
rat |
| Hao-Hao Chen, Ning Zhang, Wei-Yun Li, Ma-Rong Fang, Hui Zhang, Yuan-Shu Fang, Ming-Xing Ding, Xiao-Yan F. Overexpression of brain-derived neurotrophic factor in the hippocampus protects against post-stroke depression. Neural regeneration research. vol 10. issue 9. 2015-11-25. PMID:26604903. |
a bdnf gene lentiviral vector was injected into the hippocampus. |
2015-11-25 |
2023-08-13 |
rat |
| Hao-Hao Chen, Ning Zhang, Wei-Yun Li, Ma-Rong Fang, Hui Zhang, Yuan-Shu Fang, Ming-Xing Ding, Xiao-Yan F. Overexpression of brain-derived neurotrophic factor in the hippocampus protects against post-stroke depression. Neural regeneration research. vol 10. issue 9. 2015-11-25. PMID:26604903. |
at 7 days after injection, western blot assay and real-time quantitative pcr revealed that bdnf expression in the hippocampus was increased in depressive rats injected with bdnf lentivirus compared with depressive rats injected with control vector. |
2015-11-25 |
2023-08-13 |
rat |
| Hao-Hao Chen, Ning Zhang, Wei-Yun Li, Ma-Rong Fang, Hui Zhang, Yuan-Shu Fang, Ming-Xing Ding, Xiao-Yan F. Overexpression of brain-derived neurotrophic factor in the hippocampus protects against post-stroke depression. Neural regeneration research. vol 10. issue 9. 2015-11-25. PMID:26604903. |
these findings suggest that bdnf overexpression in the hippocampus of post-stroke depressive rats alleviates depression-like behaviors. |
2015-11-25 |
2023-08-13 |
rat |
| Thiruchelvam Kariharan, Gayani Nanayakkara, Kodeeswaran Parameshwaran, Inseyah Bagasrawala, Manuj Ahuja, Engy Abdel-Rahman, Arin T Amin, Murali Dhanasekaran, Vishnu Suppiramaniam, Rajesh H Ami. Central activation of PPAR-gamma ameliorates diabetes induced cognitive dysfunction and improves BDNF expression. Neurobiology of aging. vol 36. issue 3. 2015-11-24. PMID:25510319. |
transient transfection of constitutively active pparγ plasmid in hippocampal neuronal cells induced increased bdnf, ampa, and nmda receptors expression and spine formation. |
2015-11-24 |
2023-08-13 |
mouse |