| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Bombi Lee, Bongjun Sur, Seong-Guk Cho, Mijung Yeom, Insop Shim, Hyejung Lee, Dae-Hyun Hah. Wogonin Attenuates Hippocampal Neuronal Loss and Cognitive Dysfunction in Trimethyltin-Intoxicated Rats. Biomolecules & therapeutics. vol 24. issue 3. 2016-05-02. PMID:27133262. |
administration of wo significantly alleviated the tmt-induced loss of cholinergic immunoreactivity and restored the hippocampal expression levels of bdnf and creb proteins and their encoding mrnas to normal levels. |
2016-05-02 |
2023-08-13 |
rat |
| Tatiana Barichello, Jaqueline S Generoso, Lutiana R Simões, Vladislav G Sharin, Renan A Ceretta, Diogo Dominguini, Clarissa M Comim, Márcia C Vilela, Antonio Lucio Teixeira, João Queved. Interleukin-1β Receptor Antagonism Prevents Cognitive Impairment Following Experimental Bacterial Meningitis. Current neurovascular research. vol 12. issue 3. 2016-04-27. PMID:26044807. |
in this study, we evaluated the effects of interleukin (il)-1β receptor antagonist (il-1ra) on memory, cytokine, and brain-derived neurotrophic factor (bdnf) levels in hippocampus after experimental pneumococcal meningitis. |
2016-04-27 |
2023-08-13 |
Not clear |
| T Ghasemi, K Abnous, F Vahdati, S Mehri, B M Razavi, H Hosseinzade. Antidepressant Effect of Crocus sativus Aqueous Extract and its Effect on CREB, BDNF, and VGF Transcript and Protein Levels in Rat Hippocampus. Drug research. vol 65. issue 7. 2016-04-26. PMID:24696423. |
antidepressant effect of crocus sativus aqueous extract and its effect on creb, bdnf, and vgf transcript and protein levels in rat hippocampus. |
2016-04-26 |
2023-08-13 |
rat |
| T Ghasemi, K Abnous, F Vahdati, S Mehri, B M Razavi, H Hosseinzade. Antidepressant Effect of Crocus sativus Aqueous Extract and its Effect on CREB, BDNF, and VGF Transcript and Protein Levels in Rat Hippocampus. Drug research. vol 65. issue 7. 2016-04-26. PMID:24696423. |
in this research the molecular mechanism of antidepressant effect of aqueous extract of saffron and its effect on the levels of bdnf, vgf, creb and p-creb in rat hippocampus, were investigated. |
2016-04-26 |
2023-08-13 |
rat |
| T Ghasemi, K Abnous, F Vahdati, S Mehri, B M Razavi, H Hosseinzade. Antidepressant Effect of Crocus sativus Aqueous Extract and its Effect on CREB, BDNF, and VGF Transcript and Protein Levels in Rat Hippocampus. Drug research. vol 65. issue 7. 2016-04-26. PMID:24696423. |
the protein expression and transcript levels of bdnf, vgf creb and phospho-creb in rat hippocampus, were evaluated using western blot and quantitative reverse transcription-polymerase chain reaction (qrt-pcr). |
2016-04-26 |
2023-08-13 |
rat |
| T Ghasemi, K Abnous, F Vahdati, S Mehri, B M Razavi, H Hosseinzade. Antidepressant Effect of Crocus sativus Aqueous Extract and its Effect on CREB, BDNF, and VGF Transcript and Protein Levels in Rat Hippocampus. Drug research. vol 65. issue 7. 2016-04-26. PMID:24696423. |
it was concluded that aqueous extract of saffron has antidepressant effects and the mechanism of its antidepressant effect may be due to increasing the levels of bdnf, vgf, creb and p-creb in rat hippocampus. |
2016-04-26 |
2023-08-13 |
rat |
| Małgorzata Chalimoniuk, Stanisław J Chrapusta, Nadežda Lukačova, Józef Langfor. Endurance training upregulates the nitric oxide/soluble guanylyl cyclase/cyclic guanosine 3',5'-monophosphate pathway in the striatum, midbrain and cerebellum of male rats. Brain research. vol 1618. 2016-04-25. PMID:26006108. |
forty-eight hours after the completion of the training, the trained rats showed significantly elevated bdnf and trkb mrnas in the hippocampus, midbrain and striatum, and significantly increased bdnf levels in the hippocampus and striatum. |
2016-04-25 |
2023-08-13 |
rat |
| Zülal Kaptan, Kadriye Akgün-Dar, Ayşegül Kapucu, Huri Dedeakayoğulları, Şule Batu, Gülay Üzü. Long term consequences on spatial learning-memory of low-calorie diet during adolescence in female rats; hippocampal and prefrontal cortex BDNF level, expression of NeuN and cell proliferation in dentate gyrus. Brain research. vol 1618. 2016-04-25. PMID:26072462. |
long term consequences on spatial learning-memory of low-calorie diet during adolescence in female rats; hippocampal and prefrontal cortex bdnf level, expression of neun and cell proliferation in dentate gyrus. |
2016-04-25 |
2023-08-13 |
rat |
| Zülal Kaptan, Kadriye Akgün-Dar, Ayşegül Kapucu, Huri Dedeakayoğulları, Şule Batu, Gülay Üzü. Long term consequences on spatial learning-memory of low-calorie diet during adolescence in female rats; hippocampal and prefrontal cortex BDNF level, expression of NeuN and cell proliferation in dentate gyrus. Brain research. vol 1618. 2016-04-25. PMID:26072462. |
we hypothesized that feeding with as low as 15% low-calorie diet (lcd) during adolescence would increase hippocampal and prefrontal bdnf (brain-derived neurotrophic factor) levels, proliferative cells and neuron numbers in dentate gyrus (dg), thus positively affecting spatial memory in adulthood. |
2016-04-25 |
2023-08-13 |
rat |
| Zülal Kaptan, Kadriye Akgün-Dar, Ayşegül Kapucu, Huri Dedeakayoğulları, Şule Batu, Gülay Üzü. Long term consequences on spatial learning-memory of low-calorie diet during adolescence in female rats; hippocampal and prefrontal cortex BDNF level, expression of NeuN and cell proliferation in dentate gyrus. Brain research. vol 1618. 2016-04-25. PMID:26072462. |
hippocampus and prefrontal cortex bdnf levels were increased while serum glucose levels and level of lipid peroxidation indicator malondialdehyde in serum and hippocampus were reduced. |
2016-04-25 |
2023-08-13 |
rat |
| Maria Tikhonova, Alexander V Kuliko. Antidepressant-Like Effects of Central BDNF Administration in Mice of Antidepressant Sensitive Catalepsy (ASC) Strain. The Chinese journal of physiology. vol 55. issue 4. 2016-04-23. PMID:23282170. |
along with behavioral antidepressant-like effects on the asc mice, bdnf increased hippocampal mrna levels of bdnf and creb1 (camp response element-binding protein gene). |
2016-04-23 |
2023-08-12 |
mouse |
| Maria Tikhonova, Alexander V Kuliko. Antidepressant-Like Effects of Central BDNF Administration in Mice of Antidepressant Sensitive Catalepsy (ASC) Strain. The Chinese journal of physiology. vol 55. issue 4. 2016-04-23. PMID:23282170. |
bdnf also augmented mrna levels of arc gene encoding arc (activity-regulated cytoskeleton-associated) protein involved in bdnf-induced processes of neuronal and synaptic plasticity in hippocampus and prefrontal cortex. |
2016-04-23 |
2023-08-12 |
mouse |
| Fan-Tao Meng, Jun Zhao, Rong-Jun Ni, Hui Fang, Li-Feng Zhang, Zhi Zhang, Ya-Jing Li. Beneficial effects of enriched environment on behaviors were correlated with decreased estrogen and increased BDNF in the hippocampus of male mice. Neuro endocrinology letters. vol 36. issue 5. 2016-04-21. PMID:26707050. |
beneficial effects of enriched environment on behaviors were correlated with decreased estrogen and increased bdnf in the hippocampus of male mice. |
2016-04-21 |
2023-08-13 |
mouse |
| Naoya Hashikawa, Takumi Ogawa, Yusuke Sakamoto, Mami Ogawa, Yumi Matsuo, Yoshito Zamami, Narumi Hashikawa-Hobar. Time Course of Behavioral Alteration and mRNA Levels of Neurotrophic Factor Following Stress Exposure in Mouse. Cellular and molecular neurobiology. vol 35. issue 6. 2016-04-20. PMID:25820756. |
in the present study, we tested whether chronic stress exposure induces long-term changes in depression-related behavior, serum corticosterone, and hippocampal proliferation as well as neurotrophic factor family mrna levels, such as brain-derived neurotrophic factor (bdnf), nerve growth factor (ngf), neurotrophin-3 (nt-3), and ciliary neurotrophic factor (cntf), in the mouse hippocampus. |
2016-04-20 |
2023-08-13 |
mouse |
| Naoya Hashikawa, Takumi Ogawa, Yusuke Sakamoto, Mami Ogawa, Yumi Matsuo, Yoshito Zamami, Narumi Hashikawa-Hobar. Time Course of Behavioral Alteration and mRNA Levels of Neurotrophic Factor Following Stress Exposure in Mouse. Cellular and molecular neurobiology. vol 35. issue 6. 2016-04-20. PMID:25820756. |
mice exhibited depression-like behavior in the forced-swim test (fst) and decreased bdnf mrna and hippocampal proliferation in the middle of the stress exposure. |
2016-04-20 |
2023-08-13 |
mouse |
| Naoya Hashikawa, Takumi Ogawa, Yusuke Sakamoto, Mami Ogawa, Yumi Matsuo, Yoshito Zamami, Narumi Hashikawa-Hobar. Time Course of Behavioral Alteration and mRNA Levels of Neurotrophic Factor Following Stress Exposure in Mouse. Cellular and molecular neurobiology. vol 35. issue 6. 2016-04-20. PMID:25820756. |
after 15 days of stress exposure, we observed increased immobility in the fst, serum corticosterone levels, and bdnf mrna levels and degenerated hippocampal proliferation, maintained for at least 2 weeks. |
2016-04-20 |
2023-08-13 |
mouse |
| Sung Min Ahn, Yu Ri Kim, Ha Neui Kim, Hwa Kyoung Shin, Byung Tae Cho. Beneficial Effects of Polygonum multiflorum on Hippocampal Neuronal Cells and Mouse Focal Cerebral Ischemia. The American journal of Chinese medicine. vol 43. issue 4. 2016-04-19. PMID:26119951. |
in mcao mice, we confirmed the critical role of mature bdnf expression and creb phosphorylation by wepm in the neurons of the hippocampus. |
2016-04-19 |
2023-08-13 |
mouse |
| Sung Min Ahn, Yu Ri Kim, Ha Neui Kim, Hwa Kyoung Shin, Byung Tae Cho. Beneficial Effects of Polygonum multiflorum on Hippocampal Neuronal Cells and Mouse Focal Cerebral Ischemia. The American journal of Chinese medicine. vol 43. issue 4. 2016-04-19. PMID:26119951. |
our results suggest that wepm mainly exerted beneficial effects on hippocampal neurons through the suppression of ros accumulation and up-regulation of mature bdnf expression and creb phosphorylation. |
2016-04-19 |
2023-08-13 |
mouse |
| Li Chen, Hong Pan, Ta Anh Tuan, Ai Ling Teh, Julia L MacIsaac, Sarah M Mah, Lisa M McEwen, Yue Li, Helen Chen, Birit F P Broekman, Jan Paul Buschdorf, Yap Seng Chong, Kenneth Kwek, Seang Mei Saw, Peter D Gluckman, Marielle V Fortier, Anne Rifkin-Graboi, Michael S Kobor, Anqi Qiu, Michael J Meaney, Joanna D Holbroo. Brain-derived neurotrophic factor (BDNF) Val66Met polymorphism influences the association of the methylome with maternal anxiety and neonatal brain volumes. Development and psychopathology. vol 27. issue 1. 2016-04-18. PMID:25640836. |
thus, antenatal maternal anxiety × bdnf val66met polymorphism interactions at the level of the epigenome are reflected differently in the structure of the amygdala and the hippocampus. |
2016-04-18 |
2023-08-13 |
Not clear |
| Carla Nasca, Danielle Zelli, Benedetta Bigio, Sonia Piccinin, Sergio Scaccianoce, Robert Nisticò, Bruce S McEwe. Stress dynamically regulates behavior and glutamatergic gene expression in hippocampus by opening a window of epigenetic plasticity. Proceedings of the National Academy of Sciences of the United States of America. vol 112. issue 48. 2016-04-15. PMID:26627246. |
in wt mice after crs and in unstressed mice with a bdnf loss-of-function allele (bdnf val66met), we show that the epigenetic activator of histone acetylation, p300, plays a pivotal role in the dynamic up- and down-regulation of mglu2 in hippocampus via histone-3-lysine-27-acetylation (h3k27ac) when acute stressors are applied. |
2016-04-15 |
2023-08-13 |
mouse |