| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A L Negrón, M Beymer, G Yu, K A Warren, M Acosta-Martíne. Prolonged hyperglycemia & hyperinsulinemia increases BDNF mRNA expression in the posterior ventromedial hypothalamus and the dorsomedial hypothalamus of fed female rats. Neuroscience. vol 303. 2016-05-10. PMID:26166726. |
our results suggest that hyperinsulinemia alone does not affect bdnf mrna expression in the hypothalamus, hippocampus, or pituitary. |
2016-05-10 |
2023-08-13 |
rat |
| Sang-Hak Lee, Il-Gyu Ko, Sung-Eun Kim, Lakkyong Hwang, Jun-Jang Jin, Hyun-Hee Choi, Chang-Ju Ki. Aqueous extract of Cordyceps alleviates cerebral ischemia-induced short-term memory impairment in gerbils. Journal of exercise rehabilitation. vol 12. issue 2. 2016-05-10. PMID:27162767. |
cordyceps treatment also enhanced bdnf and trkb expressions in the hippocampus of ischemic gerbils. |
2016-05-10 |
2023-08-13 |
Not clear |
| Christopher Andrew. Towards solving enigmas in electrical injury. Critical care (London, England). vol 16. issue 2. 2016-05-09. PMID:22385987. |
recent psychiatric research indicates the importance of circulating cortisol and brain-derived neurotrophic factor (bdnf), which causes loss of hippocampal volume, in the genesis of depression. |
2016-05-09 |
2023-08-12 |
Not clear |
| Ana Kim, Anne M Fagan, Alison M Goate, Tammie L S Benzinger, John C Morris, Denise Hea. Lack of an association of BDNF Val66Met polymorphism and plasma BDNF with hippocampal volume and memory. Cognitive, affective & behavioral neuroscience. vol 15. issue 3. 2016-05-09. PMID:25784293. |
lack of an association of bdnf val66met polymorphism and plasma bdnf with hippocampal volume and memory. |
2016-05-09 |
2023-08-13 |
Not clear |
| Ana Kim, Anne M Fagan, Alison M Goate, Tammie L S Benzinger, John C Morris, Denise Hea. Lack of an association of BDNF Val66Met polymorphism and plasma BDNF with hippocampal volume and memory. Cognitive, affective & behavioral neuroscience. vol 15. issue 3. 2016-05-09. PMID:25784293. |
brain-derived neurotrophic factor (bdnf) has been shown to be important for neuronal survival and synaptic plasticity in the hippocampus in nonhuman animals. |
2016-05-09 |
2023-08-13 |
Not clear |
| Ana Kim, Anne M Fagan, Alison M Goate, Tammie L S Benzinger, John C Morris, Denise Hea. Lack of an association of BDNF Val66Met polymorphism and plasma BDNF with hippocampal volume and memory. Cognitive, affective & behavioral neuroscience. vol 15. issue 3. 2016-05-09. PMID:25784293. |
however, there have been mixed results regarding associations between either circulating bdnf or the bdnf val66met polymorphism with hippocampal volume and memory in humans. |
2016-05-09 |
2023-08-13 |
Not clear |
| Ana Kim, Anne M Fagan, Alison M Goate, Tammie L S Benzinger, John C Morris, Denise Hea. Lack of an association of BDNF Val66Met polymorphism and plasma BDNF with hippocampal volume and memory. Cognitive, affective & behavioral neuroscience. vol 15. issue 3. 2016-05-09. PMID:25784293. |
the current study examined the association of bdnf genotype and plasma bdnf with hippocampal volume and memory in two large independent cohorts of middle-aged and older adults (both cognitively normal and early-stage dementia). |
2016-05-09 |
2023-08-13 |
Not clear |
| Ana Kim, Anne M Fagan, Alison M Goate, Tammie L S Benzinger, John C Morris, Denise Hea. Lack of an association of BDNF Val66Met polymorphism and plasma BDNF with hippocampal volume and memory. Cognitive, affective & behavioral neuroscience. vol 15. issue 3. 2016-05-09. PMID:25784293. |
measures of the bdnf genotype, plasma bdnf, mri-based hippocampal volume, and memory performance were obtained from the knight alzheimer disease research center (adrc) and the alzheimer's disease neuroimaging initiative (adni). |
2016-05-09 |
2023-08-13 |
Not clear |
| Ana Kim, Anne M Fagan, Alison M Goate, Tammie L S Benzinger, John C Morris, Denise Hea. Lack of an association of BDNF Val66Met polymorphism and plasma BDNF with hippocampal volume and memory. Cognitive, affective & behavioral neuroscience. vol 15. issue 3. 2016-05-09. PMID:25784293. |
there were no significant differences between bdnf met+ and met- groups on either hippocampal volume or memory in either cohort. |
2016-05-09 |
2023-08-13 |
Not clear |
| Ana Kim, Anne M Fagan, Alison M Goate, Tammie L S Benzinger, John C Morris, Denise Hea. Lack of an association of BDNF Val66Met polymorphism and plasma BDNF with hippocampal volume and memory. Cognitive, affective & behavioral neuroscience. vol 15. issue 3. 2016-05-09. PMID:25784293. |
in addition, plasma bdnf was not significantly associated with either hippocampal volume or memory in either cohort. |
2016-05-09 |
2023-08-13 |
Not clear |
| Ana Kim, Anne M Fagan, Alison M Goate, Tammie L S Benzinger, John C Morris, Denise Hea. Lack of an association of BDNF Val66Met polymorphism and plasma BDNF with hippocampal volume and memory. Cognitive, affective & behavioral neuroscience. vol 15. issue 3. 2016-05-09. PMID:25784293. |
overall, current findings suggest that bdnf genotype and plasma bdnf may not be robust predictors for variance in hippocampal volume and memory in middle age and older adult cohorts. |
2016-05-09 |
2023-08-13 |
Not clear |
| Yuan Zhong, Yitong Zhu, Ting He, Wei Li, Hong Yan, Ya Mia. Rolipram-induced improvement of cognitive function correlates with changes in hippocampal CREB phosphorylation, BDNF and Arc protein levels. Neuroscience letters. vol 610. 2016-05-09. PMID:26552011. |
rolipram-induced improvement of cognitive function correlates with changes in hippocampal creb phosphorylation, bdnf and arc protein levels. |
2016-05-09 |
2023-08-13 |
rat |
| Yuan Zhong, Yitong Zhu, Ting He, Wei Li, Hong Yan, Ya Mia. Rolipram-induced improvement of cognitive function correlates with changes in hippocampal CREB phosphorylation, BDNF and Arc protein levels. Neuroscience letters. vol 610. 2016-05-09. PMID:26552011. |
results show that supplementation with rolipram for 23 days (0.5mg/kg, once a day) improved the performance of diabetic rats in morris water navigation task with increased level of creb, brain-derived neurotrophic factor (bdnf), and arc protein in the hippocampus. |
2016-05-09 |
2023-08-13 |
rat |
| Avik Roy, Malabendu Jana, Madhuchhanda Kundu, Grant T Corbett, Suresh B Rangaswamy, Rama K Mishra, Chi-Hao Luan, Frank J Gonzalez, Kalipada Paha. HMG-CoA Reductase Inhibitors Bind to PPARα to Upregulate Neurotrophin Expression in the Brain and Improve Memory in Mice. Cell metabolism. vol 22. issue 2. 2016-05-06. PMID:26118928. |
accordingly, simvastatin increases creb and brain-derived neurotrophic factor (bdnf) in the hippocampus of ppara null mice receiving full-length lentiviral pparα, but not l331m/y334d statin-binding domain-mutated lentiviral pparα. |
2016-05-06 |
2023-08-13 |
mouse |
| J Li, X Ding, R Zhang, W Jiang, X Sun, Z Xia, X Wang, E Wu, Y Zhang, Y H. Harpagoside ameliorates the amyloid-β-induced cognitive impairment in rats via up-regulating BDNF expression and MAPK/PI3K pathways. Neuroscience. vol 303. 2016-05-06. PMID:26135675. |
moreover, administration of har increased the expression levels of brain-derived neurotrophic factor (bdnf) and activated the extracellular-regulated protein kinase (erk) and the phosphatidylinositol 3-kinase (pi3-kinase) pathways both in the cerebral cortex and hippocampus of the aβ₁₋₄₀-insulted rat model. |
2016-05-06 |
2023-08-13 |
rat |
| A Young Min, Choon Nan Doo, Eun Jung Son, Nak Yun Sung, Kun Jong Lee, Dai-Eun Sok, Mee Ree Ki. N-palmitoyl serotonin alleviates scopolamine-induced memory impairment via regulation of cholinergic and antioxidant systems, and expression of BDNF and p-CREB in mice. Chemico-biological interactions. vol 242. 2016-05-03. PMID:26408985. |
moreover, pal-5ht suppressed the death of neuronal cells in ca1 and ca3 regions, while it restored expression of p-creb and bdnf in hippocampus. |
2016-05-03 |
2023-08-13 |
mouse |
| Yue Chen, Zhiqiang Zheng, Xi Zhu, Yujie Shi, Dandan Tian, Fengjuan Zhao, Ni Liu, Petra S Hüppi, Frederic A Troy, Bing Wan. Lactoferrin Promotes Early Neurodevelopment and Cognition in Postnatal Piglets by Upregulating the BDNF Signaling Pathway and Polysialylation. Molecular neurobiology. vol 52. issue 1. 2016-05-02. PMID:25146846. |
the importance of our new findings is that lf (1) upregulated several canonical signaling pathways associated with neurodevelopment and cognition; (2) influenced ~10 genes involved in the brain-derived neurotrophin factor (bdnf) signaling pathway in the hippocampus and upregulated the expression of polysialic acid, a marker of neuroplasticity, cell migration and differentiation of progenitor cells, and the growth and targeting of axons; (3) upregulated transcriptional and translational levels of bdnf and increased phosphorylation of the cyclic adenosine monophosphate (camp) response element-binding protein, creb, a downstream target of the bdnf signaling pathway, and a protein of crucial importance in neurodevelopment and cognition; and (4) enhanced the cognitive function and learning of piglets when tested in an eight-arm radial maze. |
2016-05-02 |
2023-08-13 |
Not clear |
| Samira S Valvassori, Camila O Arent, Amanda V Steckert, Roger B Varela, Luciano K Jornada, Paula T Tonin, Josiane Budni, Edemilson Mariot, Flávio Kapczinski, João Queved. Intracerebral Administration of BDNF Protects Rat Brain Against Oxidative Stress Induced by Ouabain in an Animal Model of Mania. Molecular neurobiology. vol 52. issue 1. 2016-05-02. PMID:25164569. |
in addition, we analyzed the bdnf levels and oxidative stress parameters (tbars, carbonyl, cat, sod, gr, and gpx) in the frontal cortex and hippocampus of rats. |
2016-05-02 |
2023-08-13 |
rat |
| Jing Han, Dong-Sheng Wang, Shui-Bing Liu, Ming-Gao Zha. Cytisine, a Partial Agonist of α4β2 Nicotinic Acetylcholine Receptors, Reduced Unpredictable Chronic Mild Stress-Induced Depression-Like Behaviors. Biomolecules & therapeutics. vol 24. issue 3. 2016-05-02. PMID:27098858. |
cyt significantly reversed the decreases of 5-ht1a, bdnf, and mtor levels in the hippocampus and amygdala. |
2016-05-02 |
2023-08-13 |
mouse |
| Jin Bae Weon, Youn Sik Jung, Choong Je M. Cognitive-Enhancing Effect of Dianthus superbus var. Longicalycinus on Scopolamine-Induced Memory Impairment in Mice. Biomolecules & therapeutics. vol 24. issue 3. 2016-05-02. PMID:27133261. |
moreover, d. superbus increased bdnf expression in the hippocampus. |
2016-05-02 |
2023-08-13 |
mouse |