| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yong Zhang, Rui Lan, Jun Wang, Xiang-Yun Li, Deng-Na Zhu, Yun-Zhi Ma, Ji-Tao Wu, Zhen-Huan Li. Acupuncture reduced apoptosis and up-regulated BDNF and GDNF expression in hippocampus following hypoxia-ischemia in neonatal rats. Journal of ethnopharmacology. vol 172. 2016-06-03. PMID:26116163. |
acupuncture reduced apoptosis and up-regulated bdnf and gdnf expression in hippocampus following hypoxia-ischemia in neonatal rats. |
2016-06-03 |
2023-08-13 |
rat |
| Peifang Jiang, Tao Zhu, Zhezhi Xia, Feng Gao, Weizhong Gu, Xi Chen, Tianming Yuan, Huimin Y. Inhibition of MAPK/ERK signaling blocks hippocampal neurogenesis and impairs cognitive performance in prenatally infected neonatal rats. European archives of psychiatry and clinical neuroscience. vol 265. issue 6. 2016-06-01. PMID:25721317. |
furthermore, inhibition of mapk/erk signaling could aggravate hippocampal neuronal apoptosis, decrease neurogenesis, and impair the offspring's cognitive performances and could also down-regulate the levels of p-erk, p-creb and bdnf. |
2016-06-01 |
2023-08-13 |
rat |
| Lei Xiang, Yanping Ren, Hao Cai, Wen Zhao, Yijun Son. MicroRNA-132 aggravates epileptiform discharges via suppression of BDNF/TrkB signaling in cultured hippocampal neurons. Brain research. vol 1622. 2016-06-01. PMID:26168887. |
in the present study, we found a dramatic upregulation of mir-132 and bdnf mrna in the hippocampal neuronal culture model of status epilepticus (se) obtained by mg(2+)-free treatment. |
2016-06-01 |
2023-08-13 |
Not clear |
| S Sugin Lal Jabaris, Haridass Sumathy, Ramesh Girish, Shridhar Narayanan, Mani Sugumar, Chidambaram Saravana Babu, Sadagopan Thanikachalam, Mohan Thanikachala. Phosphodiesterase-4 inhibitors ameliorates cognitive deficits in deoxycorticosterone acetate induced hypertensive rats via cAMP/CREB signaling system. Brain research. vol 1622. 2016-06-01. PMID:26168894. |
the mrna expression of different pde-4 subtypes along with the protein levels of pcreb and bdnf in the hippocampus was quantified. |
2016-06-01 |
2023-08-13 |
rat |
| S Sugin Lal Jabaris, Haridass Sumathy, Ramesh Girish, Shridhar Narayanan, Mani Sugumar, Chidambaram Saravana Babu, Sadagopan Thanikachalam, Mohan Thanikachala. Phosphodiesterase-4 inhibitors ameliorates cognitive deficits in deoxycorticosterone acetate induced hypertensive rats via cAMP/CREB signaling system. Brain research. vol 1622. 2016-06-01. PMID:26168894. |
our present findings suggested that pde-4 inhibitors ameliorate hypertension-induced learning impairment via camp/creb signaling that regulates bdnf expression downstream in the rat hippocampus. |
2016-06-01 |
2023-08-13 |
rat |
| A Ahmadalipour, J Sadeghzadeh, A A Vafaei, A R Bandegi, R Mohammadkhani, A Rashidy-Pou. Effects of environmental enrichment on behavioral deficits and alterations in hippocampal BDNF induced by prenatal exposure to morphine in juvenile rats. Neuroscience. vol 305. 2016-06-01. PMID:26272536. |
effects of environmental enrichment on behavioral deficits and alterations in hippocampal bdnf induced by prenatal exposure to morphine in juvenile rats. |
2016-06-01 |
2023-08-13 |
rat |
| A Ahmadalipour, J Sadeghzadeh, A A Vafaei, A R Bandegi, R Mohammadkhani, A Rashidy-Pou. Effects of environmental enrichment on behavioral deficits and alterations in hippocampal BDNF induced by prenatal exposure to morphine in juvenile rats. Neuroscience. vol 305. 2016-06-01. PMID:26272536. |
this study was designed to investigate the effects of an enriched environment on behavioral deficits and changes in hippocampal brain-derived neurotrophic factor (bdnf) levels induced by prenatal morphine in rats. |
2016-06-01 |
2023-08-13 |
rat |
| A Ahmadalipour, J Sadeghzadeh, A A Vafaei, A R Bandegi, R Mohammadkhani, A Rashidy-Pou. Effects of environmental enrichment on behavioral deficits and alterations in hippocampal BDNF induced by prenatal exposure to morphine in juvenile rats. Neuroscience. vol 305. 2016-06-01. PMID:26272536. |
on pnds 51-57, the behavioral responses including anxiety and depression-like behaviors, and passive avoidance memory as well as hippocampal bdnf levels were investigated. |
2016-06-01 |
2023-08-13 |
rat |
| A Ahmadalipour, J Sadeghzadeh, A A Vafaei, A R Bandegi, R Mohammadkhani, A Rashidy-Pou. Effects of environmental enrichment on behavioral deficits and alterations in hippocampal BDNF induced by prenatal exposure to morphine in juvenile rats. Neuroscience. vol 305. 2016-06-01. PMID:26272536. |
prenatal morphine exposure reduced hippocampal bdnf levels, but enriched environment significantly increased bdnf levels in both saline- and morphine-exposed groups. |
2016-06-01 |
2023-08-13 |
rat |
| Youri Jin, Yongsoon Par. N-3 polyunsaturated fatty acids and 17β-estradiol injection induce antidepressant-like effects through regulation of serotonergic neurotransmission in ovariectomized rats. The Journal of nutritional biochemistry. vol 26. issue 9. 2016-05-31. PMID:26022074. |
n-3 pufa and e2 decreased hippocampal expressions of interleukin (il)-6 and tumor necrosis factor-α, and increased camp response element binding protein (creb), phosphorylated creb and brain-derived neurotrophic factor (bdnf). |
2016-05-31 |
2023-08-13 |
rat |
| Xu-Feng Xu, Ting Li, Dong-Dong Wang, Bing Chen, Yue Wang, Zhe-Yu Che. Integrin-linked Kinase is Essential for Environmental Enrichment Enhanced Hippocampal Neurogenesis and Memory. Scientific reports. vol 5. 2016-05-31. PMID:26095336. |
brain-derived neurotrophic factor (bdnf) is essential for ee-induced hippocampal neurogenesis and memory enhancement. |
2016-05-31 |
2023-08-13 |
mouse |
| Xu-Feng Xu, Ting Li, Dong-Dong Wang, Bing Chen, Yue Wang, Zhe-Yu Che. Integrin-linked Kinase is Essential for Environmental Enrichment Enhanced Hippocampal Neurogenesis and Memory. Scientific reports. vol 5. 2016-05-31. PMID:26095336. |
finally, overexpressing ilk in the hippocampus could rescue the neurogenesis and memory deficits in bdnf(+/-) mice. |
2016-05-31 |
2023-08-13 |
mouse |
| Hyeon Yong Lee, Jin Bae Weon, Youn Sik Jung, Nam Young Kim, Myong Ki Kim, Choong Je M. Cognitive-Enhancing Effect of Aronia melanocarpa Extract against Memory Impairment Induced by Scopolamine in Mice. Evidence-based complementary and alternative medicine : eCAM. vol 2016. 2016-05-30. PMID:27239211. |
moreover, we determined a possible mechanism of the cognitive-enhancing effect involving ache activity and bdnf and p-creb expression in the hippocampus of mice. |
2016-05-30 |
2023-08-13 |
mouse |
| Hyeon Yong Lee, Jin Bae Weon, Youn Sik Jung, Nam Young Kim, Myong Ki Kim, Choong Je M. Cognitive-Enhancing Effect of Aronia melanocarpa Extract against Memory Impairment Induced by Scopolamine in Mice. Evidence-based complementary and alternative medicine : eCAM. vol 2016. 2016-05-30. PMID:27239211. |
a. melanocarpa berries extract reduced the acetylcholinesterase level in the hippocampus of scopolamine-injected mice and increased bdnf and p-creb expression in the hippocampus. |
2016-05-30 |
2023-08-13 |
mouse |
| Vahid Hajali, Vahid Sheibani, Hamed Ghazvini, Tahereh Ghadiri, Toktam Valizadeh, Hakimeh Saadati, Mohammad Shaban. Effect of castration on the susceptibility of male rats to the sleep deprivation-induced impairment of behavioral and synaptic plasticity. Neurobiology of learning and memory. vol 123. 2016-05-26. PMID:26079215. |
early long-term potentiation (e-ltp) was measured in area ca1 of the hippocampus and pcr and western blotting assays were employed to assess brain derived neurotrophic factor (bdnf) gene and protein expression in the hippocampus. |
2016-05-26 |
2023-08-13 |
human |
| Vahid Hajali, Vahid Sheibani, Hamed Ghazvini, Tahereh Ghadiri, Toktam Valizadeh, Hakimeh Saadati, Mohammad Shaban. Effect of castration on the susceptibility of male rats to the sleep deprivation-induced impairment of behavioral and synaptic plasticity. Neurobiology of learning and memory. vol 123. 2016-05-26. PMID:26079215. |
regardless of reproductive status, rem-sd significantly disrupted short-term memory and ltp, as well as hippocampal bdnf expression. |
2016-05-26 |
2023-08-13 |
human |
| Cong Pang, Liang Cao, Fan Wu, Li Wang, Gang Wang, Yingcong Yu, Meixi Zhang, Lichao Chen, Weijie Wang, Weihong Lv, Ling Chen, Jiejin Zhu, Jianchun Pan, Hanting Zhang, Ying Xu, Lianshu Din. The effect of trans-resveratrol on post-stroke depression via regulation of hypothalamus-pituitary-adrenal axis. Neuropharmacology. vol 97. 2016-05-24. PMID:25937213. |
moreover, mcao-induced series abnormalities related to depressive-like behaviors, such as an abnormal adrenal gland weight to body weight ratio, an increased expression of the corticotropin-releasing factor (crf) in the frontal cortex, hippocampus and hypothalamus, the differential expression of glucocorticoid receptor (gr) in these three brain regions, and a decreased brain-derived neurotrophic factor (bdnf) level, were ameliorated after treatment with increasing doses of res at 10, 20 and 40 mg/kg via gavage. |
2016-05-24 |
2023-08-13 |
Not clear |
| Liu Luo, Xiao-Long Liu, Jing Li, Rong-Hao Mu, Qing Liu, Li-Tao Yi, Di Gen. Macranthol promotes hippocampal neuronal proliferation in mice via BDNF-TrkB-PI3K/Akt signaling pathway. European journal of pharmacology. vol 762. 2016-05-24. PMID:26004527. |
our previous study has demonstrated that macranthol exerted an antidepressant-like effect in mice, at least in part, by increasing expression of hippocampal brain-derived neurotrophic factor (bdnf) expression. |
2016-05-24 |
2023-08-13 |
mouse |
| Liu Luo, Xiao-Long Liu, Jing Li, Rong-Hao Mu, Qing Liu, Li-Tao Yi, Di Gen. Macranthol promotes hippocampal neuronal proliferation in mice via BDNF-TrkB-PI3K/Akt signaling pathway. European journal of pharmacology. vol 762. 2016-05-24. PMID:26004527. |
however, the relationship between macranthol and bdnf downstream signaling pathway in the hippocampus remains unknown. |
2016-05-24 |
2023-08-13 |
mouse |
| Liu Luo, Xiao-Long Liu, Jing Li, Rong-Hao Mu, Qing Liu, Li-Tao Yi, Di Gen. Macranthol promotes hippocampal neuronal proliferation in mice via BDNF-TrkB-PI3K/Akt signaling pathway. European journal of pharmacology. vol 762. 2016-05-24. PMID:26004527. |
our results found that pharmacological inhibition of tropomyosin related kinase b (trkb) with k252a abolished the improvement of macranthol on sucrose preference and immobility time, and attenuated the stimulatory effect of macranthol on hippocampal bdnf and phospho-akt. |
2016-05-24 |
2023-08-13 |
mouse |