| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Giuseppe Musumeci, Paola Castrogiovanni, Sergio Castorina, Rosa Imbesi, Marta Anna Szychlinska, Soraya Scuderi, Carla Loreto, Salvatore Giunt. Changes in serotonin (5-HT) and brain-derived neurotrophic factor (BDFN) expression in frontal cortex and hippocampus of aged rat treated with high tryptophan diet. Brain research bulletin. vol 119. issue Pt A. 2016-08-29. PMID:26444078. |
interestingly, immunohistochemical analyses confirmed that high trp diet significantly elevates the number of 5-ht immunoreactive fibers in both brain areas tested and this correlated with bdnf increase in the fc and hippocampal regions ca1, ca2, ca3 and a strikingly down-regulation of neurotrophin levels in the dentate gyrus (dg) of aged rats. |
2016-08-29 |
2023-08-13 |
rat |
| Sandra Henriques Vaz, Sofia Rapaz Lérias, Sara Parreira, Maria José Diógenes, Ana Maria Sebastiã. Adenosine A2A receptor activation is determinant for BDNF actions upon GABA and glutamate release from rat hippocampal synaptosomes. Purinergic signalling. vol 11. issue 4. 2016-08-29. PMID:26452489. |
adenosine a2a receptor activation is determinant for bdnf actions upon gaba and glutamate release from rat hippocampal synaptosomes. |
2016-08-29 |
2023-08-13 |
rat |
| Sandra Henriques Vaz, Sofia Rapaz Lérias, Sara Parreira, Maria José Diógenes, Ana Maria Sebastiã. Adenosine A2A receptor activation is determinant for BDNF actions upon GABA and glutamate release from rat hippocampal synaptosomes. Purinergic signalling. vol 11. issue 4. 2016-08-29. PMID:26452489. |
we thus evaluated the role of a(2a)r on the modulatory effect of bdnf upon glutamate and gaba release from isolated hippocampal nerve terminals (synaptosomes). |
2016-08-29 |
2023-08-13 |
rat |
| Wen-Xue Liu, Jing Wang, Ze-Min Xie, Ning Xu, Guang-Fen Zhang, Min Jia, Zhi-Qiang Zhou, Kenji Hashimoto, Jian-Jun Yan. Regulation of glutamate transporter 1 via BDNF-TrkB signaling plays a role in the anti-apoptotic and antidepressant effects of ketamine in chronic unpredictable stress model of depression. Psychopharmacology. vol 233. issue 3. 2016-08-29. PMID:26514555. |
growing evidence suggests that downregulated clearance of glutamate and signaling pathways involving brain-derived neurotrophic factor (bdnf) and its receptor trkb play a role in morphological changes in the hippocampus of depressed patients. |
2016-08-29 |
2023-08-13 |
Not clear |
| Ernest Palomer, Javier Carretero, Stefano Benvegnù, Carlos G Dotti, Mauricio G Marti. Neuronal activity controls Bdnf expression via Polycomb de-repression and CREB/CBP/JMJD3 activation in mature neurons. Nature communications. vol 7. 2016-08-29. PMID:27010597. |
in this work we show that bdnf promoters are repressed by polycomb complex 2 in mature hippocampal neurons, and basal expression is guaranteed by the coexistence with activating histone marks. |
2016-08-29 |
2023-08-13 |
Not clear |
| Li-Tao Yi, Liu Luo, Yong-Jing Wu, Bin-Bin Liu, Xiao-Long Liu, Di Geng, Qing Li. Circadian variations in behaviors, BDNF and cell proliferation in depressive mice. Metabolic brain disease. vol 30. issue 6. 2016-08-23. PMID:26183613. |
considering the circadian rhythm of bdnf expression, our present study evaluated the circadian variations in behaviors, serum corticosterone concentrations, hippocampal bdnf expression and neuronal cell proliferation in mice exposed to chronic mild stress (cms), one of the most widely used depression-like animal models. |
2016-08-23 |
2023-08-13 |
mouse |
| Li-Tao Yi, Liu Luo, Yong-Jing Wu, Bin-Bin Liu, Xiao-Long Liu, Di Geng, Qing Li. Circadian variations in behaviors, BDNF and cell proliferation in depressive mice. Metabolic brain disease. vol 30. issue 6. 2016-08-23. PMID:26183613. |
cms exposure might destroy the circadian rhythm of bdnf expression and cell proliferation in hippocampus of normal individual. |
2016-08-23 |
2023-08-13 |
mouse |
| Peng Lei, Scott Ayton, Ambili Thoppuvalappil Appukuttan, Irene Volitakis, Paul A Adlard, David I Finkelstein, Ashley I Bus. Clioquinol rescues Parkinsonism and dementia phenotypes of the tau knockout mouse. Neurobiology of disease. vol 81. 2016-08-22. PMID:25796563. |
treatment also reversed cognitive deficits and raised bdnf levels in the hippocampus, which was accompanied by attenuated brain atrophy, and reduced iron content in the brain. |
2016-08-22 |
2023-08-13 |
mouse |
| Raffaella Alò, Maria Mele, Gilda Fazzari, Ennio Avolio, Marcello Canonac. Exposure to sub-chronic unpredictable stress accounts for antidepressant-like effects in hamsters treated with BDNF and CNQX. Brain research bulletin. vol 118. 2016-08-22. PMID:26409118. |
sub-chronic administration of bdnf in the hippocampal dentate gyrus (dg) of stressed hamsters was responsible for very evident (p<0.001) sucrose consumption along with notably elevated swimming bouts and reduced immobility states in the forced swim test (fst). |
2016-08-22 |
2023-08-13 |
Not clear |
| Jing Sun, Fangyan Wang, Guangliang Hong, Mengqi Pang, Hailing Xu, Haixiao Li, Feng Tian, Renchi Fang, Ye Yao, Jiaming Li. Antidepressant-like effects of sodium butyrate and its possible mechanisms of action in mice exposed to chronic unpredictable mild stress. Neuroscience letters. vol 618. 2016-08-22. PMID:26957230. |
then changes of nissl's body in the hippocampus, brain serotonin (5-ht) concentration, brain-derived neurotrophic factor (bdnf) and tight junctions (tjs) proteins level were assessed to explore the antidepressant mechanisms. |
2016-08-22 |
2023-08-13 |
mouse |
| Jing Sun, Fangyan Wang, Guangliang Hong, Mengqi Pang, Hailing Xu, Haixiao Li, Feng Tian, Renchi Fang, Ye Yao, Jiaming Li. Antidepressant-like effects of sodium butyrate and its possible mechanisms of action in mice exposed to chronic unpredictable mild stress. Neuroscience letters. vol 618. 2016-08-22. PMID:26957230. |
our results showed that cums caused significant depression-like behaviors, neuropathological changes, and decreased brain 5-ht concentration, tjs protein levels and bdnf expression in the hippocampus. |
2016-08-22 |
2023-08-13 |
mouse |
| Jing Sun, Fangyan Wang, Guangliang Hong, Mengqi Pang, Hailing Xu, Haixiao Li, Feng Tian, Renchi Fang, Ye Yao, Jiaming Li. Antidepressant-like effects of sodium butyrate and its possible mechanisms of action in mice exposed to chronic unpredictable mild stress. Neuroscience letters. vol 618. 2016-08-22. PMID:26957230. |
however, nab treatment significantly ameliorated behavioral deficits of the cums-induced mice, increased 5-ht concentration, increased bdnf expression, and up-regulated occludin and zonula occludens-1(zo-1) protein levels in the hippocampus, which demonstrated that nab could partially restore cums-induced blood-brain barrier (bbb) impairments. |
2016-08-22 |
2023-08-13 |
mouse |
| Ana Carolina de Moura, Virgínia Meneghini Lazzari, Roberta Oriques Becker, Mirela Severo Gil, Carina Anicet Ruthschilling, Grasiela Agnes, Silvana Almeida, Ana Beatriz Gorini da Veiga, Aldo Bolten Lucion, Márcia Giovenard. Gene expression in the CNS of lactating rats with different patterns of maternal behavior. Neuroscience research. vol 99. 2016-08-19. PMID:26003743. |
this study aimed to analyze the gene expression of the receptors for dopamine (drd1a), prolactin (prlr), serotonin (htr1a, htr1b), estrogen (esr1, esr2), and of bdnf in the olfactory bulb (ob), hippocampus (hp), prefrontal cortex (pfc), and striatum (st) of wistar rats from three groups: ll (n = 8); hl (n = 8); virgin females in diestrus (d; n = 6). |
2016-08-19 |
2023-08-13 |
rat |
| Li Chen, Yang Yao, Changjuan Wei, Yanan Sun, Xiaofeng Ma, Rongxin Zhang, Xiaolin Xu, Junwei Ha. T cell immunity to glatiramer acetate ameliorates cognitive deficits induced by chronic cerebral hypoperfusion by modulating the microenvironment. Scientific reports. vol 5. 2016-08-19. PMID:26391515. |
the results suggest that ga reduced cognitive deficits by reestablishing an optimal microenvironment such as increasing expression of the brain-derived neurotrophic factor (bdnf) and modulating the th1/th2 cytokine balance in the hippocampus. |
2016-08-19 |
2023-08-13 |
rat |
| G Naert, C Zussy, C Tran Van Ba, N Chevallier, Y-P Tang, T Maurice, L Givaloi. Involvement of Endogenous Brain-Derived Neurotrophic Factor in Hypothalamic-Pituitary-Adrenal Axis Activity. Journal of neuroendocrinology. vol 27. issue 11. 2016-08-18. PMID:26388293. |
delivery of sirna in the rat brain decreased bdnf levels in the hippocampus (-31%) and hypothalamus (-35%) but not in the amygdala, frontal cortex and pituitary. |
2016-08-18 |
2023-08-13 |
mouse |
| G Naert, C Zussy, C Tran Van Ba, N Chevallier, Y-P Tang, T Maurice, L Givaloi. Involvement of Endogenous Brain-Derived Neurotrophic Factor in Hypothalamic-Pituitary-Adrenal Axis Activity. Journal of neuroendocrinology. vol 27. issue 11. 2016-08-18. PMID:26388293. |
in kd mice, bdnf levels in the hippocampus and hypothalamus were decreased by 20% in heterozygous and by 60% in homozygous animals compared to wild-type littermates. |
2016-08-18 |
2023-08-13 |
mouse |
| Yoshihisa Kitamura, Sayo Hattori, Saori Yoneda, Saori Watanabe, Erika Kanemoto, Misaki Sugimoto, Toshiki Kawai, Ayumi Machida, Hirotaka Kanzaki, Ikuko Miyazaki, Masato Asanuma, Toshiaki Send. Doxorubicin and cyclophosphamide treatment produces anxiety-like behavior and spatial cognition impairment in rats: Possible involvement of hippocampal neurogenesis via brain-derived neurotrophic factor and cyclin D1 regulation. Behavioural brain research. vol 292. 2016-08-17. PMID:26057360. |
however, hippocampal bdnf levels and bdnf mrna levels were not decreased by this treatment. |
2016-08-17 |
2023-08-13 |
rat |
| Yoshihisa Kitamura, Sayo Hattori, Saori Yoneda, Saori Watanabe, Erika Kanemoto, Misaki Sugimoto, Toshiki Kawai, Ayumi Machida, Hirotaka Kanzaki, Ikuko Miyazaki, Masato Asanuma, Toshiaki Send. Doxorubicin and cyclophosphamide treatment produces anxiety-like behavior and spatial cognition impairment in rats: Possible involvement of hippocampal neurogenesis via brain-derived neurotrophic factor and cyclin D1 regulation. Behavioural brain research. vol 292. 2016-08-17. PMID:26057360. |
these results suggest that the co-administration of doxorubicin and cyclophosphamide induces psychological and cognitive impairment, in addition to negatively affecting hippocampal neurogenesis, which may be related to hippocampal cyclin d1 levels, but not hippocampal bdnf levels. |
2016-08-17 |
2023-08-13 |
rat |
| Tuğçe Demirtaş Şahin, Ayşe Karson, Fuat Balcı, Yusufhan Yazır, Dilek Bayramgürler, Tijen Utka. TNF-alpha inhibition prevents cognitive decline and maintains hippocampal BDNF levels in the unpredictable chronic mild stress rat model of depression. Behavioural brain research. vol 292. 2016-08-17. PMID:26112756. |
tnf-alpha inhibition prevents cognitive decline and maintains hippocampal bdnf levels in the unpredictable chronic mild stress rat model of depression. |
2016-08-17 |
2023-08-13 |
rat |
| Tuğçe Demirtaş Şahin, Ayşe Karson, Fuat Balcı, Yusufhan Yazır, Dilek Bayramgürler, Tijen Utka. TNF-alpha inhibition prevents cognitive decline and maintains hippocampal BDNF levels in the unpredictable chronic mild stress rat model of depression. Behavioural brain research. vol 292. 2016-08-17. PMID:26112756. |
the current study aimed to investigate the effect of ucms on the cognitive performance of rats and their hippocampal bdnf levels and the effect of chronic infliximab (5mg/kg/weekly, i.p.) |
2016-08-17 |
2023-08-13 |
rat |