| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| E Stragier, V Martin, E Davenas, C Poilbout, R Mongeau, R Corradetti, L Lanfume. Brain plasticity and cognitive functions after ethanol consumption in C57BL/6J mice. Translational psychiatry. vol 5. 2016-09-26. PMID:26670281. |
however, we recently reported that chronic and moderate ethanol intake in c57bl/6j mice induced chromatin remodeling within the bdnf promoters, leading to both enhanced brain-derived neurotrophic factor (bdnf) expression and hippocampal neurogenesis under free-choice protocol. |
2016-09-26 |
2023-08-13 |
mouse |
| E Stragier, V Martin, E Davenas, C Poilbout, R Mongeau, R Corradetti, L Lanfume. Brain plasticity and cognitive functions after ethanol consumption in C57BL/6J mice. Translational psychiatry. vol 5. 2016-09-26. PMID:26670281. |
we showed that a 3-week chronic free-choice ethanol consumption in c57bl/6j mice led to a decrease in dna methylation of the bdnf gene within the ca1 and ca3 subfields of the hippocampus, and upregulated hippocampal bdnf signaling pathways mediated by erk, akt and creb. |
2016-09-26 |
2023-08-13 |
mouse |
| Jin-Fang Ge, Ya-Yun Xu, Gan Qin, Xue-Yin Pan, Jiang-Qun Cheng, Fei-Hu Che. Nesfatin-1, a potent anorexic agent, decreases exploration and induces anxiety-like behavior in rats without altering learning or memory. Brain research. vol 1629. 2016-09-22. PMID:26498879. |
moreover, the protein expression of brain-derived neurotrophic factor (bdnf), total and phosphorylated-erk in the hippocampus and the prefrontal cortex (pfc) were evaluated. |
2016-09-22 |
2023-08-13 |
rat |
| Jin-Fang Ge, Ya-Yun Xu, Gan Qin, Xue-Yin Pan, Jiang-Qun Cheng, Fei-Hu Che. Nesfatin-1, a potent anorexic agent, decreases exploration and induces anxiety-like behavior in rats without altering learning or memory. Brain research. vol 1629. 2016-09-22. PMID:26498879. |
furthermore, 3 weeks' consecutive administration of nesfatin-1 resulted in the decrease of protein expression of bdnf and phosphorylated-erk in the hippocampus and the pfc. |
2016-09-22 |
2023-08-13 |
rat |
| Jin-Fang Ge, Ya-Yun Xu, Gan Qin, Xue-Yin Pan, Jiang-Qun Cheng, Fei-Hu Che. Nesfatin-1, a potent anorexic agent, decreases exploration and induces anxiety-like behavior in rats without altering learning or memory. Brain research. vol 1629. 2016-09-22. PMID:26498879. |
these results provided evidence that exogenous nesfatin-1 could decrease exploration and induce anxiety-like behavior in rats, the mechanism of which might be related to the reduced protein expression of bdnf and phosphorylated-erk in the hippocampus and the pfc. |
2016-09-22 |
2023-08-13 |
rat |
| Arnab Choudhury, Seema Singh, Gautam Palit, Shubha Shukla, Surajit Gangul. Administration of N-acetylserotonin and melatonin alleviate chronic ketamine-induced behavioural phenotype accompanying BDNF-independent and dependent converging cytoprotective mechanisms in the hippocampus. Behavioural brain research. vol 297. 2016-09-20. PMID:26475510. |
in spite of this fundamental difference in modulating bdnf levels in the upstream events, both mlt and nas seem to overlap in the trkb-induced downstream pro-survival mechanisms in the hippocampus, providing protection against nmdar-hypofunction related cellular events. |
2016-09-20 |
2023-08-13 |
mouse |
| Osamu Nakagawasai, Wataru Nemoto, Hiroshi Onogi, Takahiro Moriya, Jia-Rong Lin, Takayo Odaira, Fukie Yaoita, Takumi Ogawa, Kiminori Ohta, Yasuyuki Endo, Koichi Tan-N. BE360, a new selective estrogen receptor modulator, produces antidepressant and antidementia effects through the enhancement of hippocampal cell proliferation in olfactory bulbectomized mice. Behavioural brain research. vol 297. 2016-09-20. PMID:26497104. |
immunoblotting studies revealed that pcreb and bdnf were significantly increased in the hippocampus of obx mice treated with be360. |
2016-09-20 |
2023-08-13 |
mouse |
| Daiany D B Redivo, Anne K Schreiber, Eliana R Adami, Deidiane E Ribeiro, Samia R L Joca, Janaína M Zanoveli, Joice M Cunh. Effect of omega-3 polyunsaturated fatty acid treatment over mechanical allodynia and depressive-like behavior associated with experimental diabetes. Behavioural brain research. vol 298. issue Pt B. 2016-09-20. PMID:26546881. |
moreover, it was observed that dbt animals had significantly lower levels of bdnf in both hippocampus and pre frontal cortex when compared to ngl rats, which is completely prevented by fo treatment. |
2016-09-20 |
2023-08-13 |
rat |
| Zegang Ma, Guilin Wang, Lin Cui, Qimin Wan. Myricetin Attenuates Depressant-Like Behavior in Mice Subjected to Repeated Restraint Stress. International journal of molecular sciences. vol 16. issue 12. 2016-09-20. PMID:26633366. |
the effects of myricetin on the brain-derived neurotrophic factor (bdnf) levels in hippocampus were also investigated. |
2016-09-20 |
2023-08-13 |
mouse |
| Zegang Ma, Guilin Wang, Lin Cui, Qimin Wan. Myricetin Attenuates Depressant-Like Behavior in Mice Subjected to Repeated Restraint Stress. International journal of molecular sciences. vol 16. issue 12. 2016-09-20. PMID:26633366. |
the protective effects of myricetin might be partially mediated by an influence on bdnf levels and might be attributed to myricetin-mediated anti-oxidative stress in the hippocampus. |
2016-09-20 |
2023-08-13 |
mouse |
| Jiali Li, Yixiao Luo, Ruoxi Zhang, Haishui Shi, Weili Zhu, Jie Sh. Neuropeptide Trefoil Factor 3 Reverses Depressive-Like Behaviors by Activation of BDNF-ERK-CREB Signaling in Olfactory Bulbectomized Rats. International journal of molecular sciences. vol 16. issue 12. 2016-09-20. PMID:26633367. |
to elucidate the mechanism underlying the antidepressant-like activity of tff3, we tested the role of brain-derived neurotrophic factor (bdnf)-extracellular signal-related kinase (erk)-cyclic adenosine monophosphate response element binding protein (creb) signaling in the hippocampus in the process. |
2016-09-20 |
2023-08-13 |
rat |
| Cheng-Fu Li, Xue-Mei Chen, Shao-Mei Chen, Rong-Hao Mu, Bin-Bin Liu, Liu Luo, Xiao-Long Liu, Di Geng, Qing Liu, Li-Tao Y. Activation of hippocampal BDNF signaling is involved in the antidepressant-like effect of the NMDA receptor antagonist 7-chlorokynurenic acid. Brain research. vol 1630. 2016-09-19. PMID:26562663. |
activation of hippocampal bdnf signaling is involved in the antidepressant-like effect of the nmda receptor antagonist 7-chlorokynurenic acid. |
2016-09-19 |
2023-08-13 |
mouse |
| Cheng-Fu Li, Xue-Mei Chen, Shao-Mei Chen, Rong-Hao Mu, Bin-Bin Liu, Liu Luo, Xiao-Long Liu, Di Geng, Qing Liu, Li-Tao Y. Activation of hippocampal BDNF signaling is involved in the antidepressant-like effect of the NMDA receptor antagonist 7-chlorokynurenic acid. Brain research. vol 1630. 2016-09-19. PMID:26562663. |
in addition, 7-chlorokynurenic acid significantly reversed the cums-induced down-regulation of bdnf, p-erk, p-akt, psd-95, synapsin i and cell proliferation in the hippocampus. |
2016-09-19 |
2023-08-13 |
mouse |
| Cheng-Fu Li, Xue-Mei Chen, Shao-Mei Chen, Rong-Hao Mu, Bin-Bin Liu, Liu Luo, Xiao-Long Liu, Di Geng, Qing Liu, Li-Tao Y. Activation of hippocampal BDNF signaling is involved in the antidepressant-like effect of the NMDA receptor antagonist 7-chlorokynurenic acid. Brain research. vol 1630. 2016-09-19. PMID:26562663. |
in conclusion, our findings suggest that the antidepressant-like effect of 7-chlorokynurenic acid may be mediated, at least in part, by activating bdnf signaling in the hippocampus. |
2016-09-19 |
2023-08-13 |
mouse |
| Jun Shen, Junjian Zhang, Min Deng, Yue Liu, Yuan Hu, Lei Zhan. The Antidepressant Effect of Angelica sinensis Extracts on Chronic Unpredictable Mild Stress-Induced Depression Is Mediated via the Upregulation of the BDNF Signaling Pathway in Rats. Evidence-based complementary and alternative medicine : eCAM. vol 2016. 2016-09-19. PMID:27642354. |
moreover, the expression of brain derived neurotrophic factor (bdnf) and the phosphorylation of camp-response element binding protein (creb) and extracellular signal-regulated protein kinase (erk 1/2) were markedly decreased in the hippocampus in depressed rats. |
2016-09-19 |
2023-08-13 |
rat |
| Jun Shen, Junjian Zhang, Min Deng, Yue Liu, Yuan Hu, Lei Zhan. The Antidepressant Effect of Angelica sinensis Extracts on Chronic Unpredictable Mild Stress-Induced Depression Is Mediated via the Upregulation of the BDNF Signaling Pathway in Rats. Evidence-based complementary and alternative medicine : eCAM. vol 2016. 2016-09-19. PMID:27642354. |
in conclusion, in the present study, we show that as extracts exerted antidepressant effects that were mediated by the bdnf signaling pathway: in as-treated depressed rats, the expression of the bdnf protein and the phosphorylation of its downstream targets (erk 1/2, creb) were upregulated in the hippocampus. |
2016-09-19 |
2023-08-13 |
rat |
| Jing Ma, Fei Liu, Peng Liu, Ying-Ying Dong, Zheng Chu, Tie-Zhou Hou, Yong-Hui Dan. Impact of early developmental fluoride exposure on the peripheral pain sensitivity in mice. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 47. issue Pt B. 2016-09-16. PMID:26431775. |
in addition, the expression of hippocampal brain-derived neurotrophic factor (bdnf) was also evaluated by western blotting. |
2016-09-16 |
2023-08-13 |
mouse |
| Jing Ma, Fei Liu, Peng Liu, Ying-Ying Dong, Zheng Chu, Tie-Zhou Hou, Yong-Hui Dan. Impact of early developmental fluoride exposure on the peripheral pain sensitivity in mice. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 47. issue Pt B. 2016-09-16. PMID:26431775. |
the results suggest that early developmental fluoride exposure may lower the basal pain threshold and be associated with the increasing of bdnf expression in hippocampus. |
2016-09-16 |
2023-08-13 |
mouse |
| M Schmidt, C Brandwein, A Luoni, P Sandrini, T Calzoni, M Deuschle, F Cirulli, M A Riva, P Gas. Morc1 knockout evokes a depression-like phenotype in mice. Behavioural brain research. vol 296. 2016-09-15. PMID:26275923. |
cort plasma levels did not differ significantly between morc1(-/-) mice and their wildtype littermates, yet - surprisingly - total bdnf mrna-levels in the hippocampus were up-regulated in morc1(-/-) animals. |
2016-09-15 |
2023-08-13 |
mouse |
| Jochen De Vry, Tim Vanmierlo, Pilar Martínez-Martínez, Mario Losen, Yasin Temel, Janneke Boere, Gunter Kenis, Thomas Steckler, Harry W M Steinbusch, Marc De Baets, Jos Prickaert. TrkB in the hippocampus and nucleus accumbens differentially modulates depression-like behavior in mice. Behavioural brain research. vol 296. 2016-09-15. PMID:26315459. |
brain-derived neurotrophic factor (bdnf) exerts antidepressant-like effects in the hippocampus and pro-depressant effects in the nucleus accumbens (nac). |
2016-09-15 |
2023-08-13 |
mouse |