| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Tuğçe Demirtaş Şahin, Ayşe Karson, Fuat Balcı, Yusufhan Yazır, Dilek Bayramgürler, Tijen Utka. TNF-alpha inhibition prevents cognitive decline and maintains hippocampal BDNF levels in the unpredictable chronic mild stress rat model of depression. Behavioural brain research. vol 292. 2016-08-17. PMID:26112756. |
these behavioral effects of ucms were accompanied by reduction in the level of bdnf in the ca1 and ca3 regions of the hippocampus. |
2016-08-17 |
2023-08-13 |
rat |
| Tuğçe Demirtaş Şahin, Ayşe Karson, Fuat Balcı, Yusufhan Yazır, Dilek Bayramgürler, Tijen Utka. TNF-alpha inhibition prevents cognitive decline and maintains hippocampal BDNF levels in the unpredictable chronic mild stress rat model of depression. Behavioural brain research. vol 292. 2016-08-17. PMID:26112756. |
chronic infliximab treatment prevented the ucms-induced cognitive impairments as well as the reduction in the levels of hippocampal brain-derived neurotrophic factor (bdnf). |
2016-08-17 |
2023-08-13 |
rat |
| Jin-Fang Ge, Ya-Yun Xu, Ning Li, Yue Zhang, Guo-Liang Qiu, Cheng-Hao Chu, Cai-Yun Wang, Gan Qin, Fei-Hu Che. Resveratrol improved the spatial learning and memory in subclinical hypothyroidism rat induced by hemi-thyroid electrocauterization. Endocrine journal. vol 62. issue 10. 2016-08-17. PMID:26228795. |
the protein expressions of synaptotagmin-1 (syt-1) and brain-derived neurotrophic factor (bdnf) in the hippocampus were measured via western blot. |
2016-08-17 |
2023-08-13 |
rat |
| Jin-Fang Ge, Ya-Yun Xu, Ning Li, Yue Zhang, Guo-Liang Qiu, Cheng-Hao Chu, Cai-Yun Wang, Gan Qin, Fei-Hu Che. Resveratrol improved the spatial learning and memory in subclinical hypothyroidism rat induced by hemi-thyroid electrocauterization. Endocrine journal. vol 62. issue 10. 2016-08-17. PMID:26228795. |
furthermore, res treatment up-regulated the protein levels of syt-1 and bdnf in hippocampus. |
2016-08-17 |
2023-08-13 |
rat |
| Jin-Fang Ge, Ya-Yun Xu, Ning Li, Yue Zhang, Guo-Liang Qiu, Cheng-Hao Chu, Cai-Yun Wang, Gan Qin, Fei-Hu Che. Resveratrol improved the spatial learning and memory in subclinical hypothyroidism rat induced by hemi-thyroid electrocauterization. Endocrine journal. vol 62. issue 10. 2016-08-17. PMID:26228795. |
these findings indicated an amelioration effect of res on the spatial learning and memory in the sch rats, the mechanism of which might be involved with its ability of modifying the hyperactive hpt axis and up-regulating the hippocampal hypo-expression of syt-1 and bdnf. |
2016-08-17 |
2023-08-13 |
rat |
| Wenjuan Yu, Hao Zhu, Yueming Wang, Guanjun Li, Lihua Wang, Huafang L. Reactive Transformation and Increased BDNF Signaling by Hippocampal Astrocytes in Response to MK-801. PloS one. vol 10. issue 12. 2016-08-17. PMID:26700309. |
reactive transformation and increased bdnf signaling by hippocampal astrocytes in response to mk-801. |
2016-08-17 |
2023-08-13 |
rat |
| Wenjuan Yu, Hao Zhu, Yueming Wang, Guanjun Li, Lihua Wang, Huafang L. Reactive Transformation and Increased BDNF Signaling by Hippocampal Astrocytes in Response to MK-801. PloS one. vol 10. issue 12. 2016-08-17. PMID:26700309. |
treatment of cultured hippocampal astrocytes with mk-801 enhanced protein and mrna levels of bdnf, trkb, and p75. |
2016-08-17 |
2023-08-13 |
rat |
| Wenjuan Yu, Hao Zhu, Yueming Wang, Guanjun Li, Lihua Wang, Huafang L. Reactive Transformation and Increased BDNF Signaling by Hippocampal Astrocytes in Response to MK-801. PloS one. vol 10. issue 12. 2016-08-17. PMID:26700309. |
collectively, our results suggest that hippocampal astrocytes may contribute to the pathophysiology of schizophrenia symptoms associated with nmda receptor hypofunction by reactive transformation and altered bdnf signaling. |
2016-08-17 |
2023-08-13 |
rat |
| Zhi-wei Yang, Fei Wu, Sheng-Li Zhan. Effects of ganoderic acids on epileptiform discharge hippocampal neurons: insights from alterations of BDNF,TRPC3 and apoptosis. Die Pharmazie. vol 71. issue 6. 2016-08-17. PMID:27455554. |
effects of ganoderic acids on epileptiform discharge hippocampal neurons: insights from alterations of bdnf,trpc3 and apoptosis. |
2016-08-17 |
2023-08-13 |
rat |
| Zhi-wei Yang, Fei Wu, Sheng-Li Zhan. Effects of ganoderic acids on epileptiform discharge hippocampal neurons: insights from alterations of BDNF,TRPC3 and apoptosis. Die Pharmazie. vol 71. issue 6. 2016-08-17. PMID:27455554. |
in this work, rat primary hippocampal neurons in an in vitro model were used to assess the intervention effects of gas on epileptiform discharge hippocampal neurons and expression of both bdnf and trpc3, with the aid of immunofluorescence, mtt method and flow cytometry. |
2016-08-17 |
2023-08-13 |
rat |
| S Liang, T Wang, X Hu, J Luo, W Li, X Wu, Y Duan, F Ji. Administration of Lactobacillus helveticus NS8 improves behavioral, cognitive, and biochemical aberrations caused by chronic restraint stress. Neuroscience. vol 310. 2016-08-15. PMID:26408987. |
l. helveticus ns8 also resulted in lower plasma corticosterone (cort) and adrenocorticotropic hormone (acth) levels, higher plasma interleukin-10 (il-10) levels, restored hippocampal serotonin (5-ht) and norepinephrine (ne) levels, and more hippocampal brain-derived neurotrophic factor (bdnf) mrna expression than in chronic stress rats. |
2016-08-15 |
2023-08-13 |
rat |
| Sören Enge, Monika Fleischhauer, Anne Gärtner, Andreas Reif, Klaus-Peter Lesch, Matthias Kliegel, Alexander Strobe. Brain-Derived Neurotrophic Factor (Val66Met) and Serotonin Transporter (5-HTTLPR) Polymorphisms Modulate Plasticity in Inhibitory Control Performance Over Time but Independent of Inhibitory Control Training. Frontiers in human neuroscience. vol 10. 2016-08-15. PMID:27524961. |
in line with ample evidence on bdnf and bdnf-5-ht system interactions to induce (rapid) plasticity especially in hippocampal regions and in response to environmental demands, the findings may reflect genotype-dependent differences in the acquisition and consolidation of task-relevant information, thereby facilitating a more adaptive responding to task-specific requirements. |
2016-08-15 |
2023-08-13 |
Not clear |
| Min Sun, Ke Wang, Yan Yu, Wen-Ting Su, Xin-Xin Jiang, Jian Yang, Jun Jia, Xiao-Min Wan. Electroacupuncture Alleviates Depressive-Like Symptoms and Modulates BDNF Signaling in 6-Hydroxydopamine Rats. Evidence-based complementary and alternative medicine : eCAM. vol 2016. 2016-08-15. PMID:27525025. |
noticeably, ea treatment reversed the 6-ohda-induced abnormal expression of brain-derived neurotrophic factor (bdnf) and tropomyosin-related kinase b (trkb) in the midbrain and hippocampus. |
2016-08-15 |
2023-08-13 |
rat |
| Jing-Hui Song, Jin-Tai Yu, Lan Ta. Brain-Derived Neurotrophic Factor in Alzheimer's Disease: Risk, Mechanisms, and Therapy. Molecular neurobiology. vol 52. issue 3. 2016-08-10. PMID:25354497. |
brain-derived neurotrophic factor (bdnf) has a neurotrophic support on neuron of central nervous system (cns) and is a key molecule in the maintenance of synaptic plasticity and memory storage in hippocampus. |
2016-08-10 |
2023-08-13 |
Not clear |
| Ji-Hong Liu, Qiang-Long You, Mei-Dan Wei, Qian Wang, Zheng-Yi Luo, Song Lin, Lang Huang, Shu-Ji Li, Xiao-Wen Li, Tian-Ming Ga. Social Isolation During Adolescence Strengthens Retention of Fear Memories and Facilitates Induction of Late-Phase Long-Term Potentiation. Molecular neurobiology. vol 52. issue 3. 2016-08-10. PMID:25860250. |
social isolation during adolescence also increased brain-derived neurotrophic factor (bdnf) expression in the hippocampus, and application of a tropomyosin-related kinase b (trkb) receptor inhibitor ameliorated the facilitated l-ltp seen after isolation. |
2016-08-10 |
2023-08-13 |
mouse |
| Christina Spilker, Sven Nullmeier, Katarzyna M Grochowska, Anne Schumacher, Ioana Butnaru, Tamar Macharadze, Guilherme M Gomes, PingAn Yuanxiang, Gonca Bayraktar, Carolin Rodenstein, Carolin Geiseler, Angela Kolodziej, Jeffrey Lopez-Rojas, Dirk Montag, Frank Angenstein, Julia Bär, Wolfgang D'Hanis, Thomas Roskoden, Marina Mikhaylova, Eike Budinger, Frank W Ohl, Oliver Stork, Ana C Zenclussen, Anna Karpova, Herbert Schwegler, Michael R Kreut. A Jacob/Nsmf Gene Knockout Results in Hippocampal Dysplasia and Impaired BDNF Signaling in Dendritogenesis. PLoS genetics. vol 12. issue 3. 2016-08-09. PMID:26977770. |
a jacob/nsmf gene knockout results in hippocampal dysplasia and impaired bdnf signaling in dendritogenesis. |
2016-08-09 |
2023-08-13 |
mouse |
| Christina Spilker, Sven Nullmeier, Katarzyna M Grochowska, Anne Schumacher, Ioana Butnaru, Tamar Macharadze, Guilherme M Gomes, PingAn Yuanxiang, Gonca Bayraktar, Carolin Rodenstein, Carolin Geiseler, Angela Kolodziej, Jeffrey Lopez-Rojas, Dirk Montag, Frank Angenstein, Julia Bär, Wolfgang D'Hanis, Thomas Roskoden, Marina Mikhaylova, Eike Budinger, Frank W Ohl, Oliver Stork, Ana C Zenclussen, Anna Karpova, Herbert Schwegler, Michael R Kreut. A Jacob/Nsmf Gene Knockout Results in Hippocampal Dysplasia and Impaired BDNF Signaling in Dendritogenesis. PLoS genetics. vol 12. issue 3. 2016-08-09. PMID:26977770. |
nsmf knockout (ko) mice show reduced hippocampal bdnf mrna and protein levels as well as reduced pcreb levels during dendritogenesis. |
2016-08-09 |
2023-08-13 |
mouse |
| Christina Spilker, Sven Nullmeier, Katarzyna M Grochowska, Anne Schumacher, Ioana Butnaru, Tamar Macharadze, Guilherme M Gomes, PingAn Yuanxiang, Gonca Bayraktar, Carolin Rodenstein, Carolin Geiseler, Angela Kolodziej, Jeffrey Lopez-Rojas, Dirk Montag, Frank Angenstein, Julia Bär, Wolfgang D'Hanis, Thomas Roskoden, Marina Mikhaylova, Eike Budinger, Frank W Ohl, Oliver Stork, Ana C Zenclussen, Anna Karpova, Herbert Schwegler, Michael R Kreut. A Jacob/Nsmf Gene Knockout Results in Hippocampal Dysplasia and Impaired BDNF Signaling in Dendritogenesis. PLoS genetics. vol 12. issue 3. 2016-08-09. PMID:26977770. |
taken together, the data suggest that the absence of jacob in early development interrupts a positive feedback loop between bdnf signaling, subsequent nuclear import of jacob, activation of creb and enhanced bdnf gene transcription, ultimately leading to hippocampal dysplasia. |
2016-08-09 |
2023-08-13 |
mouse |
| Ling-yun Hui, Ya-wen Wang, Fu-ling Zhou, Xian-cang Ma, Run-zhi Yan, Lin Zhang, Quan-li Wang, Xuewen Y. Association Between MKP-1, BDNF, and Gonadal Hormones with Depression on Perimenopausal Women. Journal of women's health (2002). vol 25. issue 1. 2016-08-08. PMID:26176177. |
studies suggest that brain-derived neurotrophic factor (bdnf) exerts effects on the neuronal function of hippocampal neurons and increases hippocampal mitogen-activated protein kinase phosphatase-1 (mkp-1) expression, which causes depressive behaviors in rat or mouse. |
2016-08-08 |
2023-08-13 |
mouse |
| Hee Ra Park, Ju Yeon Kim, Yujeong Lee, Hye Jeong Chun, Young Whan Choi, Hwa Kyoung Shin, Byung Tae Choi, Cheol Min Kim, Jaewon Le. PMC-12, a traditional herbal medicine, enhances learning memory and hippocampal neurogenesis in mice. Neuroscience letters. vol 617. 2016-08-08. PMID:26917101. |
in addition, pmc-12 increased the levels of bdnf, p-creb, and synaptophysin, which are known to be associated with neural plasticity and hippocampal neurogenesis. |
2016-08-08 |
2023-08-13 |
mouse |