| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Halil Asci, Onur Erol, Hamit Yasar Ellidag, Esra Nur Tola, Mehtap Savran, Ozlem Ozme. Pathology of cigarettes on the reproductive system and ameliorative effects of alpha lipoic acid: A rat model study. Toxicology and industrial health. vol 34. issue 6. 2018-10-15. PMID:29591887. |
the aim of this work was to demonstrate the pathological and immunohistochemical effects of cs and the protective effects of a strong antioxidant alpha lipoic acid (ala) on cs-induced genital system changes in a rat model. |
2018-10-15 |
2023-08-13 |
rat |
| Neslihan Pınar, Gökhan Çakırca, Tümay Özgür, Mahir Kapla. The protective effects of alpha lipoic acid on methotrexate induced testis injury in rats. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 97. 2018-10-05. PMID:29793311. |
in this study, we aimed to investigate the protective effects of alpha lipoic acid (ala) on mtx-induced testicle damage in a rat model. |
2018-10-05 |
2023-08-13 |
rat |
| Z K El-Maddawy, W S H Abd El Nab. Effects of ivermectin and its combination with alpha lipoic acid on expression of IGFBP-3 and HSPA1 genes and male rat fertility. Andrologia. vol 50. issue 3. 2018-09-20. PMID:28880400. |
either alone or combined with alpha lipoic acid (ala) (50 mg/kg b.wt daily) on expression of testicular insulin-like growth factor binding protein-3 (igfbp-3) and heat-shock protein a1 (hspa1)) genes in the testes, as well as on male rat fertility parameters. |
2018-09-20 |
2023-08-13 |
rat |
| Asmaa M S Gomaa, Nashwa A Abd El-Mottaleb, Hazem A Aame. Antioxidant and anti-inflammatory activities of alpha lipoic acid protect against indomethacin-induced gastric ulcer in rats. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 101. 2018-09-13. PMID:29486337. |
little is known about the role of tumor necrosis factor-alpha (tnf-α), plasminogen activator inhibitor-1 (pai-1), and inducible nitric oxide synthase (inos) in the gastric ulcer and the effect of alpha lipoic acid (ala) in their modulation. |
2018-09-13 |
2023-08-13 |
rat |
| Marzena Zając, Rafał Świąte. The effect of hemp seed and linseed addition on the quality of liver pâtés. Acta scientiarum polonorum. Technologia alimentaria. vol 17. issue 2. 2018-08-30. PMID:29803219. |
hemp seeds are valuable because of their fat and protein content and linseed is known for its high α-linolenic fatty acid (ala) content. |
2018-08-30 |
2023-08-13 |
Not clear |
| Ola A Hussein, Amel M M Abdel-Hafez, Ayat Abd El Karei. Rat hippocampal CA3 neuronal injury induced by limb ischemia/reperfusion: A possible restorative effect of alpha lipoic acid. Ultrastructural pathology. vol 42. issue 2. 2018-08-28. PMID:29466087. |
alpha lipoic acid (ala) is an endogenous antioxidant with a powerful antioxidative, anti-inflammatory, and antiapoptotic properties. |
2018-08-28 |
2023-08-13 |
rat |
| Riya Ganguly, Devin Hasanally, Aleksandra Stamenkovic, Thane G Maddaford, Rakesh Chaudhary, Grant N Pierce, Amir Ravand. Alpha linolenic acid decreases apoptosis and oxidized phospholipids in cardiomyocytes during ischemia/reperfusion. Molecular and cellular biochemistry. vol 437. issue 1-2. 2018-07-09. PMID:28634855. |
the omega-3 fatty acid, alpha linolenic acid (ala) found in plant-derived foods induces significant cardiovascular benefits when ingested. |
2018-07-09 |
2023-08-13 |
rat |
| Vladislav Victorovich Khrustalev, Tatyana Aleksandrovna Khrustaleva, Sergey Vladimirovich Lelevic. Ethanol binding sites on proteins. Journal of molecular graphics & modelling. vol 78. 2018-07-09. PMID:29078103. |
residues of ala, ile and arg preferably bind ethanol when they are included in an alpha helix. |
2018-07-09 |
2023-08-13 |
Not clear |
| Martin H de Borst, Leandro C Baia, Ellen K Hoogeveen, Erik J Giltay, Gerjan Navis, Stephan J L Bakker, Johanna M Geleijnse, Daan Kromhout, Sabita S Soedamah-Muth. Effect of Omega-3 Fatty Acid Supplementation on Plasma Fibroblast Growth Factor 23 Levels in Post-Myocardial Infarction Patients with Chronic Kidney Disease: The Alpha Omega Trial. Nutrients. vol 9. issue 11. 2018-07-09. PMID:29137111. |
in the randomized double-blind alpha omega trial, 4837 patients with a history of myocardial infarction aged 60-80 years (81% men) were randomized to one of four trial margarines supplemented with a targeted additional intake of 400 mg/day epa and dha, 2 g/day ala, epa-dha plus ala, or placebo for 41 months. |
2018-07-09 |
2023-08-13 |
Not clear |
| R G Gomes, C B Silva, S M González, R L Oliveira, M C Max, L A Lisboa, T R R Barreiros, M M Santos, F D Sarapião, E L Gastal, M M Sened. Alpha lipoic acid (ALA) effects on developmental competence of equine preantral follicles in short-term culture. Theriogenology. vol 105. 2018-06-26. PMID:28982027. |
alpha lipoic acid (ala) effects on developmental competence of equine preantral follicles in short-term culture. |
2018-06-26 |
2023-08-13 |
Not clear |
| R G Gomes, C B Silva, S M González, R L Oliveira, M C Max, L A Lisboa, T R R Barreiros, M M Santos, F D Sarapião, E L Gastal, M M Sened. Alpha lipoic acid (ALA) effects on developmental competence of equine preantral follicles in short-term culture. Theriogenology. vol 105. 2018-06-26. PMID:28982027. |
the effect of different concentrations of alpha lipoic acid (ala) on the development and morphology of preantral follicles, as well as the proliferative activity of granulosa cells, was assessed after short-term culture. |
2018-06-26 |
2023-08-13 |
Not clear |
| Izabela Szulc-Kielbik, Michal Kielbik, Magdalena Klin. Ferulic acid but not alpha-lipoic acid effectively protects THP-1-derived macrophages from oxidant and pro-inflammatory response to LPS. Immunopharmacology and immunotoxicology. vol 39. issue 6. 2018-06-21. PMID:28872362. |
in this study, we compare the anti-inflammatory/antioxidant activity of two compounds available as supplements: alpha lipoic acid (ala) and ferulic acid (fa). |
2018-06-21 |
2023-08-13 |
Not clear |
| R Ejaz, M S Ansari, B A Rakha, S Qadeer, A U Husna, S Akhte. Evaluation of α-linolenic acid for freezability and in vivo fertility of Nili Ravi (Bubalus bubalis) buffalo semen. Theriogenology. vol 104. 2018-06-13. PMID:28802112. |
alpha linolenic acid (ala) is integral component of cell membrane that protects the cell in stressful events and involves in many metabolic pathways. |
2018-06-13 |
2023-08-13 |
Not clear |
| Mohamed El-Komy, Suzan Shalaby, Rehab Hegazy, Rania Abdel Hay, Saly Sherif, Ehab Benda. Assessment of cubosomal alpha lipoic acid gel efficacy for the aging face: a single-blinded, placebo-controlled, right-left comparative clinical study. Journal of cosmetic dermatology. vol 16. issue 3. 2018-05-22. PMID:27873449. |
a poloxamer solution acting as a vehicle for the lipid base particulate system (cubosome dispersions) containing alpha lipoic acid (ala) has achieved encouraging results in skin aging. |
2018-05-22 |
2023-08-13 |
Not clear |
| Oya Soylu Karapinar, Neslihan Pinar, Oğuzhan Özcan, Tümay Özgür, Kenan Dolapçıoğl. Protective effect of alpha-lipoic acid in methotrexate-induced ovarian oxidative injury and decreased ovarian reserve in rats. Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology. vol 33. issue 8. 2018-05-22. PMID:28361557. |
to determine whether the possible oxidative effect of methotrexate (mtx) on ovary and to evaluate the effectiveness of alpha lipoic acid (ala), which may be useful in many oxidative stress models. |
2018-05-22 |
2023-08-13 |
rat |
| Oya Soylu Karapinar, Neslihan Pinar, Oğuzhan Özcan, Tümay Özgür, Kenan Dolapçıoğl. Protective effect of alpha-lipoic acid in methotrexate-induced ovarian oxidative injury and decreased ovarian reserve in rats. Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology. vol 33. issue 8. 2018-05-22. PMID:28361557. |
thirty-two female wistar-albino rats were randomly divided into four groups; control group, alpha lipoic acid group (ala 100 mg/kg, 10 days), multiple dose mtx group (mtx 1 mg/kg 1, 3, 5, 7 days) and mtx and ala group (mtx 1 mg/kg 1, 3, 5, 7 days and ala 100 mg/kg, 10 days). |
2018-05-22 |
2023-08-13 |
rat |
| F A Al-Qahtani, M Arafah, B Sharma, N J Siddiq. Effects of alpha lipoic acid on acrylamide-induced hepatotoxicity in rats. Cellular and molecular biology (Noisy-le-Grand, France). vol 63. issue 6. 2018-05-22. PMID:28968200. |
alpha-lipoic acid (ala) is a naturally occurring antioxidant whose therapeutic effect has been related to its antioxidant activity. this study was carried out to study the protective effect of alpha lipoic acid on acrylamide induced perturbations in rat liver. four groups of rats were studied viz., control rats, acrylamide treated rats, alpha lipoic acid treated rats, and alpha lipoic acid plus acrylamide treated rats. |
2018-05-22 |
2023-08-13 |
rat |
| Bahriye Horasanli, Askin Esen Hasturk, Murat Arikan, Guray Togral, Fatma Helvacioglu, Atilla Dagdeviren, Senem Mut, Ferhat Harman, Guldeniz Argu. Comparative evaluation of the electrophysiological, functional and ultrastructural effects of alpha lipoic acid and cyanocobalamin administration in a rat model of sciatic nerve injury. Journal of back and musculoskeletal rehabilitation. vol 30. issue 5. 2018-05-11. PMID:28968230. |
vitamin b12 and alpha lipoic acid (ala) are known to promote functional and morphological recovery after peripheral nerve injury. |
2018-05-11 |
2023-08-13 |
rat |
| Birendra Mishra, Ryan Ripperdan, Laura Ortiz, Ulrike Ludere. Very low doses of heavy oxygen ion radiation induce premature ovarian failure. Reproduction (Cambridge, England). vol 154. issue 2. 2018-04-09. PMID:28528322. |
adult female mice were irradiated with 0, 5, 30 or 50 cgy oxygen ions or 50 cgy oxygen plus dietary supplementation with the antioxidant alpha lipoic acid (ala). |
2018-04-09 |
2023-08-13 |
mouse |
| Hossein Hejr, Majid Ghareghani, Kazem Zibara, Maryam Ghafari, Farzad Sadri, Zinab Salehpour, Azadeh Hamedi, Koresh Negintaji, Hassan Azari, Amir Ghanbar. The ratio of 1/3 linoleic acid to alpha linolenic acid is optimal for oligodendrogenesis of embryonic neural stem cells. Neuroscience letters. vol 651. 2018-03-26. PMID:28504119. |
in this study, we investigated the effect of various concentrations and ratios of linoleic acid (la) and alpha linolenic acid (ala), which belong respectively to omega-6 and omega-3 pufas, on the proliferation and differentiation of enscs.results showed that low (25 and 50μm) or high (100 and 200μm) concentrations of ala, but not la, and the ratio of 1:3 of la/ala significantly increased neurospheres size, frequency and cell numbers, in comparison to controls. |
2018-03-26 |
2023-08-13 |
Not clear |