| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Guofu Li, Jiahong Fu, Yang Zhao, Kaiqiang Ji, Ting Luan, Bin Zan. Alpha-lipoic acid exerts anti-inflammatory effects on lipopolysaccharide-stimulated rat mesangial cells via inhibition of nuclear factor kappa B (NF-κB) signaling pathway. Inflammation. vol 38. issue 2. 2015-12-18. PMID:24962643. |
our data indicated that ala pretreatment reduced lps-stimulated release of inflammatory cytokines, such as tumor necrosis factor alpha (tnf-α), interleukin (il)-1 beta (il-1β), as well as il-6, in hbzy-1 cell supernatant. |
2015-12-18 |
2023-08-13 |
rat |
| Guofu Li, Jiahong Fu, Yang Zhao, Kaiqiang Ji, Ting Luan, Bin Zan. Alpha-lipoic acid exerts anti-inflammatory effects on lipopolysaccharide-stimulated rat mesangial cells via inhibition of nuclear factor kappa B (NF-κB) signaling pathway. Inflammation. vol 38. issue 2. 2015-12-18. PMID:24962643. |
lps-enhanced phosphorylation of nuclear factor kappa b (nf-κb) inhibitor alpha (iκbα) and iκb kinase alpha/beta (ikkα/β) and nuclear translocation of nf-κb subunit p65 in hbzy-1 cells were inhibited by ala pretreatment. |
2015-12-18 |
2023-08-13 |
rat |
| Amrita Khaire, Richa Rathod, Nisha Kemse, Anvita Kale, Sadhana Josh. Supplementation with omega-3 fatty acids during gestation and lactation to a vitamin B12-deficient or -supplemented diet improves pregnancy outcome and metabolic variables in Wistar rats. Reproduction, fertility, and development. vol 27. issue 2. 2015-10-29. PMID:24355403. |
the amount of vitamin b12 in the supplemented group was 0.50 μg kg(-1) diet and n-3 pufa was alpha linolenic acid (ala) 1.68, eicosapentaenoic acid 5.64, docosahexaenoic acid (dha) 3.15 (g per 100g fatty acids per kg diet). |
2015-10-29 |
2023-08-12 |
rat |
| Alaa El-Din E El-Sisi, Magda E El-Syaad, Karima I El-Desoky, Ethar A Mouss. Protective effects of alpha lipoic acid versus N-acetylcysteine on ifosfamide-induced nephrotoxicity. Toxicology and industrial health. vol 31. issue 2. 2015-10-15. PMID:23299189. |
therefore, this study was carried out to investigate the possible underlying mechanisms that may be involved in ifo-induced nephrotoxicity, including free radical generation and the possible role of alpha lipoic acid (ala) versus n-acetylcysteine (nac) in protection against this toxicity. |
2015-10-15 |
2023-08-12 |
rat |
| R Dokuyucu, A Karateke, H Gokce, R K Kurt, O Ozcan, S Ozturk, Z A Tas, F Karateke, M Dur. Antioxidant effect of erdosteine and lipoic acid in ovarian ischemia-reperfusion injury. European journal of obstetrics, gynecology, and reproductive biology. vol 183. 2015-08-18. PMID:25461347. |
to investigate the effects of erdosteine and alpha lipoic acid (ala) in a rat model of ovarian ischaemia-reperfusion injury. |
2015-08-18 |
2023-08-13 |
rat |
| Heung Yong Jin, Kyung Ae Lee, Jin Zu Wu, Hong Sun Baek, Tae Sun Par. The neuroprotective benefit from pioglitazone (PIO) addition on the alpha lipoic acid (ALA)-based treatment in experimental diabetic rats. Endocrine. vol 47. issue 3. 2015-07-23. PMID:24532138. |
the neuroprotective benefit from pioglitazone (pio) addition on the alpha lipoic acid (ala)-based treatment in experimental diabetic rats. |
2015-07-23 |
2023-08-12 |
rat |
| Heung Yong Jin, Kyung Ae Lee, Jin Zu Wu, Hong Sun Baek, Tae Sun Par. The neuroprotective benefit from pioglitazone (PIO) addition on the alpha lipoic acid (ALA)-based treatment in experimental diabetic rats. Endocrine. vol 47. issue 3. 2015-07-23. PMID:24532138. |
in this study, we investigated the combined effect of pioglitazone (pio) with alpha lipoic acid (ala) on the peripheral nerves of diabetic rats. |
2015-07-23 |
2023-08-12 |
rat |
| Nemat Khan, Richard Gordon, Trent M Woodruff, Maree T Smit. Antiallodynic effects of alpha lipoic acid in an optimized RR-EAE mouse model of MS-neuropathic pain are accompanied by attenuation of upregulated BDNF-TrkB-ERK signaling in the dorsal horn of the spinal cord. Pharmacology research & perspectives. vol 3. issue 3. 2015-07-14. PMID:26171221. |
in an experimental autoimmune encephalomyelitis (eae)-mouse model of ms, chronic alpha lipoic acid (ala) treatment reduced clinical disease severity, but ms-neuropathic pain was not assessed. |
2015-07-14 |
2023-08-13 |
mouse |
| Thelma P Polyviou, Yannis P Pitsiladis, Carlos Celis-Morales, Benjamin Brown, John R Speakman, Dalia Malkov. The Effects of Hyperhydrating Supplements Containing Creatine and Glucose on Plasma Lipids and Insulin Sensitivity in Endurance-Trained Athletes. Journal of amino acids. vol 2015. 2015-07-13. PMID:26167296. |
the study aimed to determine whether ingestion of glucose (glu) simultaneously with cr and glycerol (cr/gly) supplement is detrimental to plasma lipids of endurance-trained individuals and find out whether modification arising can be attenuated by replacing part of the glu with alpha lipoic acid (ala). |
2015-07-13 |
2023-08-13 |
Not clear |
| Javid Safa, Mohammad Reza Ardalan, Mohammadamin Rezazadehsaatlou, Mehran Mesgari, Reza Mahdavi, Maryam Poorkar Jadi. Effects of alpha lipoic acid supplementation on serum levels of IL-8 and TNF-α in patient with ESRD undergoing hemodialysis. International urology and nephrology. vol 46. issue 8. 2015-05-11. PMID:24729102. |
oxidative stresses [like interleukin-8 (il-8) and tumor necrosis factor-alpha (tnf-α)] and inflammation are the main risk factors associated with cardiovascular diseases and other complications in many organs in hemodialysis patients; meanwhile, antioxidants like alpha lipoic acid (ala) may reduce the oxidative stress markers and the levels of inflammatory cytokines, so can improve of the patient's quality of life. |
2015-05-11 |
2023-08-13 |
Not clear |
| Yun Li, Hongwei Shen, Jingming Shi, Luosheng Tan. The effects of alpha lipoic acid in preventing oxidative stress-induced retinal pigment epithelial cell injury. Canadian journal of physiology and pharmacology. vol 92. issue 9. 2015-04-14. PMID:25179747. |
this study evaluated the protective effect of alpha lipoic acid (ala) in human adult retinal pigment epithelium cells (arpe-19). |
2015-04-14 |
2023-08-13 |
human |
| Sahar Hatami, Saeed Zavareh, Mojdeh Salehnia, Taghi Lashkarbolouki, Isaac Karim. Comparison of oxidative status of mouse pre-antral follicles derived from vitrified whole ovarian tissue and vitrified pre-antral follicles in the presence of alpha lipoic acid. The journal of obstetrics and gynaecology research. vol 40. issue 6. 2015-04-13. PMID:24888934. |
the main goal of this study was to compare developmental competence and oxidative status of vitrified-warmed pre-antral follicles (vpf) with pre-antral follicles derived from vitrified-warmed ovarian tissue (vof) in the presence of alpha lipoic acid (ala). |
2015-04-13 |
2023-08-13 |
mouse |
| Rodrigo Valenzuela B, Cynthia Barrera R, Marcela González-Astorga, Julio Sanhueza C, Alfonso Valenzuela . Alpha linolenic acid (ALA) from Rosa canina, sacha inchi and chia oils may increase ALA accretion and its conversion into n-3 LCPUFA in diverse tissues of the rat. Food & function. vol 5. issue 7. 2015-02-23. PMID:24855655. |
alpha linolenic acid (ala) from rosa canina, sacha inchi and chia oils may increase ala accretion and its conversion into n-3 lcpufa in diverse tissues of the rat. |
2015-02-23 |
2023-08-13 |
human |
| Kwi-Hyun Bae, Ae-Kyung Min, Jung-Guk Kim, In-Kyu Lee, Keun-Gyu Par. Alpha lipoic acid induces hepatic fibroblast growth factor 21 expression via up-regulation of CREBH. Biochemical and biophysical research communications. vol 455. issue 3-4. 2015-02-10. PMID:25449271. |
alpha lipoic acid (ala), a naturally occurring thiol antioxidant, has been shown to induce metabolic changes that are similar to those induced by fgf21, including weight loss and increased energy expenditure. |
2015-02-10 |
2023-08-13 |
mouse |
| Sahar Hatami, Saeed Zavareh, Mojdeh Salehnia, Taghi Lashkarbolouki, Mohammad Taghi Ghorbanian, Isaac Karim. Total oxidative status of mouse vitrified pre-antral follicles with pre-treatment of alpha lipoic acid. Iranian biomedical journal. vol 18. issue 3. 2015-01-07. PMID:24842145. |
the aim of the present study was to evaluate reactive oxygen species (ros) and total antioxidant capacity (tac) levels of mouse vitrified pre-antral follicles in the presence of alpha lipoic acid (ala). |
2015-01-07 |
2023-08-13 |
mouse |
| Saly Sherif, Ehab R Bendas, Sabry Badaw. The clinical efficacy of cosmeceutical application of liquid crystalline nanostructured dispersions of alpha lipoic acid as anti-wrinkle. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. vol 86. issue 2. 2014-11-07. PMID:24056055. |
topical 5% alpha lipoic acid (ala) has shown efficacy in treatment of photo-damaged skin. |
2014-11-07 |
2023-08-12 |
human |
| Sarah Juel Paulsen, Leif Kongskov Larsen, Gitte Hansen, Shekar Chelur, Philip Just Larsen, Niels Vran. Expression of the fatty acid receptor GPR120 in the gut of diet-induced-obese rats and its role in GLP-1 secretion. PloS one. vol 9. issue 2. 2014-10-13. PMID:24520357. |
subsequently we investigated the effect of gpr120 receptor stimulation with the long chain fatty acid alpha linolenic acid (ala) on glp-1 secretion in rats. |
2014-10-13 |
2023-08-12 |
rat |
| Ingeborg A Brouwer, Johanna M Geleijnse, Veronique M Klaasen, Liesbeth A Smit, Erik J Giltay, Janette de Goede, Annemieke C Heijboer, Daan Kromhout, Martijn B Kata. Effect of alpha linolenic acid supplementation on serum prostate specific antigen (PSA): results from the alpha omega trial. PloS one. vol 8. issue 12. 2014-09-29. PMID:24349086. |
alpha linolenic acid (ala) is the major omega-3 fatty acid in the diet. |
2014-09-29 |
2023-08-12 |
Not clear |
| Marisa Durand, Núria Mac. [Alpha lipoic acid and its antioxidant against cancer and diseases of central sensitization]. Nutricion hospitalaria. vol 28. issue 4. 2014-06-25. PMID:23889618. |
the alpha lipoic acid (ala) may control and limit the production of free radicals, influencing the development of pathologies such cancer or central sensitization diseases. |
2014-06-25 |
2023-08-12 |
Not clear |
| D Vasudevan, Manoj M Naik, Qayum I Mukadda. Efficacy and safety of methylcobalamin, alpha lipoic acid and pregabalin combination versus pregabalin monotherapy in improving pain and nerve conduction velocity in type 2 diabetes associated impaired peripheral neuropathic condition. [MAINTAIN]: Results of a pilot study. Annals of Indian Academy of Neurology. vol 17. issue 1. 2014-04-22. PMID:24753654. |
to assess whether methylcobalamin and alpha lipoic acid (ala) added to pregabalin provide additional benefit compared to pregabalin alone in type 2 diabetes mellitus associated peripheral neuropathy. |
2014-04-22 |
2023-08-13 |
Not clear |