| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Triantafyllos Didangelos, Eleni Karlafti, Evangelia Kotzakioulafi, Parthena Giannoulaki, Zisis Kontoninas, Anastasia Kontana, Polykarpos Evripidou, Christos Savopoulos, Andreas L Birkenfeld, Konstantinos Kantartzi. Efficacy and Safety of the Combination of Palmitoylethanolamide, Superoxide Dismutase, Alpha Lipoic Acid, Vitamins B12, B1, B6, E, Mg, Zn and Nicotinamide for 6 Months in People with Diabetic Neuropathy. Nutrients. vol 16. issue 18. 2024-09-28. PMID:39339645. |
to investigate the efficacy of palmitoylethanolamide (pea, 300 mg), superoxide dismutase (sod, 70 ui), alpha lipoic acid (ala, 300 mg), vitamins b6 (1.5 mg), b1 (1.1 mg), b12 (2.5 mcg), e (7.5 mg), nicotinamide (9 mg), and minerals (mg 30 mg, zn 2.5 mg) in one tablet in people with diabetic neuropathy (dn). |
2024-09-28 |
2024-10-01 |
Not clear |
| Deepti Nayyar, Joanne M Said, Helen McCarthy, Deanne H Hryciw, Lannie O'Keefe, Andrew J McAinc. Effect of a High Linoleic Acid Diet on Pregnant Women and Their Offspring. Nutrients. vol 16. issue 17. 2024-09-14. PMID:39275331. |
essential fatty acids, linoleic acid (la) and alpha linoleic acid (ala), can only be obtained in the diet. |
2024-09-14 |
2024-09-17 |
human |
| Florencia Hidalgo, Anabela C Ferretti, Carla Borini Etichetti, Emilia Baffo, Alejandro P Pariani, Tomás Rivabella Maknis, Javier Bussi, Javier E Girardini, María C Larocca, Cristián Favr. Alpha lipoic acid diminishes migration and invasion in hepatocellular carcinoma cells through an AMPK-p53 axis. Scientific reports. vol 14. issue 1. 2024-09-11. PMID:39261583. |
alpha lipoic acid (ala), an indirect ampk activator that inhibits hepatic steatosis, shows antitumor effects in different cancers. |
2024-09-11 |
2024-09-14 |
Not clear |
| Ghadeer M Albadrani, Ahmed E Altyar, Osama A Kensara, Mohie A M Haridy, Mohamed Sayed Zaazouee, Alaa Ahmed Elshanbary, Amany A Sayed, Mohamed M Abdel-Dai. Effects of Alfa lipoic acid and Co-enzyme Q10 treatment on AFB1-induced oxidative, inflammatory, and DNA damages in rats. Toxicon : official journal of the International Society on Toxinology. 2024-09-02. PMID:39222753. |
the study aimed to evaluate the protective effect of alpha lipoic acid (ala) and/or co-enzyme q10 (cq10) against the harmful effects of afb1 on the liver and kidneys. |
2024-09-02 |
2024-09-05 |
human |
| Burak Dik, Durmus Hatipoglu, Mehmet Burak Ate. Potential effects of Resatorvid and alpha lipoic acid on gentamicin-induced nephrotoxicity in rats. Pharmacology research & perspectives. vol 12. issue 4. 2024-07-12. PMID:38992963. |
this study investigated the potential of resatorvid and alpha lipoic acid (ala) in mitigating gentamicin-induced nephrotoxicity in rats, considering biochemical, histopathological, and molecular parameters. |
2024-07-12 |
2024-07-14 |
rat |
| Kamal Awad, Stephen Leroy Newhart, Leticia Brotto, Marco Brott. Lipidomics Profiling of the Linoleic Acid Metabolites After Whole-Body Vibration in Humans. Methods in molecular biology (Clifton, N.J.). vol 2816. 2024-07-08. PMID:38977603. |
linoleic acid (la) and alpha linoleic acid (ala) are types of omega 3 fatty acids that possess inflammatory properties and promote resolution of inflammation either through their own actions or through their metabolites known as oxylipins. |
2024-07-08 |
2024-07-12 |
human |
| Elshymaa A Abdelnaby, Mohamed Fathi, Noha Y Salem, Eman S Ramadan, Shimaa G Yehia, Ibrahim A Emam, Ali Salama, Haney Samir, Hossam R El-Sherbin. Outcomes of dietary alpha-lipoic acid on testicular vascularization, steroid hormones, and seminal quality in aged Baladi bucks. BMC veterinary research. vol 20. issue 1. 2024-07-05. PMID:38969980. |
alpha lipoic acid (ala) is a potent antioxidant, that diffuses freely in aqueous and lipid phases, possessing anti-inflammatory and anti-apoptotic properties. |
2024-07-05 |
2024-07-08 |
Not clear |
| Gabriela Barrientos, Mariano L Schuman, Maria S Landa, Elizabeth Robello, Claudio Incardona, Melanie L Conrad, Monica Galleano, Silvia I Garcí. Therapeutic Effect of Alpha Lipoic Acid in a Rat Preclinical Model of Preeclampsia: Focus on Maternal Signs, Fetal Growth and Placental Function. Antioxidants (Basel, Switzerland). vol 13. issue 6. 2024-06-27. PMID:38929169. |
here, we hypothesized that supplementation with alpha lipoic acid (ala), a potent antioxidant, during early pregnancy could ameliorate the pe phenotype in this model. |
2024-06-27 |
2024-06-29 |
rat |
| Sadaf Nouripour, Soghra Mehri, Tahereh Aminifard, Arezoo Hosseini, Abolfazl Khajavi Rad, Amirhossein Jafarian, Hossein Hosseinzade. Protective role of alpha-lipoic acid against rhabdomyolysis-induced acute kidney injury in rats. Iranian journal of basic medical sciences. vol 27. issue 8. 2024-06-24. PMID:38911241. |
alpha lipoic acid (ala), an organosulfur compound known for its anti-oxidant and anti-inflammatory properties, was examined in this study for its potential impact on rhabdomyolysis-induced aki in rats. |
2024-06-24 |
2024-06-26 |
rat |
| L V S Ñaupas, F D R Gomes, A C A Ferreira, S M Morais, D R Alves, D I A Teixeira, B G Alves, Y Watanabe, J R Figueiredo, G M Tetaping, A P R Rodrigue. Alpha lipoic acid controls degeneration and ensures follicular development in ovine ovarian tissue cultured in vitro. Theriogenology. vol 225. 2024-05-25. PMID:38795511. |
this study aims to evaluate the effects of adding alpha lipoic acid (ala) to the in vitro ovarian tissue culture medium, either fresh or after vitrification/warming. |
2024-05-25 |
2024-05-31 |
Not clear |
| Mianmian Jiang, Huiping Zhu, Xiaoding Zhou, Xiaobing Zhai, Shiyang Li, Wenzhi Ma, Keyang Liu, Jinhong Cao, Ehab S Esha. Associations of dietary linoleic acid and alpha linolenic acid intake with cardiovascular, cancer and all-cause mortalities in patients with diabetes: NHANES 1999-2008. Frontiers in clinical diabetes and healthcare. vol 5. 2024-05-10. PMID:38721345. |
to investigate the association between the dietary intake of linoleic acid (la) and alpha linolenic acid (ala) with mortality outcomes in patients with diabetes. |
2024-05-10 |
2024-05-27 |
Not clear |
| Alessandro D Genazzani, Christian Battipaglia, Laura Rusce, Greta Prampolini, Claudia Aio, Francesco Ricciardiello, Martina Foschi, Alessandra Sponzilli, Elisa Semprini, Tabatha Petrill. Alpha lipoic acid administration improved both peripheral sensitivity to insulin and liver clearance of insulin reducing potential risk of diabetes and nonalcoholic fatty liver disease in overweight/obese PCOS patients. Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology. vol 40. issue 1. 2024-04-16. PMID:38622970. |
to evaluate the effects of alpha lipoic acid (ala) on hormonal and metabolic parameters in a group of overweight/obese polycystic ovary syndrome (pcos) patients. |
2024-04-16 |
2024-04-18 |
Not clear |
| Estefany Rengifo, Juan D Rios-Mera, Patricia Huamaní, Rafael Vela-Paredes, Jessy Vásquez, Erick Saldaña, Raúl Siche, Fernando Tell. Fish Burgers Fortified with Microencapsulated Sacha Inchi Oil: Effects on Technological and Sensory Properties. Foods (Basel, Switzerland). vol 13. issue 7. 2024-04-13. PMID:38611310. |
the long-chain omega-3 fatty acids alpha linolenic acid (ala), eicosapentaenoic acid (epa), and docosahexaenoic acid (dha) have proven health benefits, but it is not common to find them together in a processed food product. |
2024-04-13 |
2024-04-15 |
Not clear |
| Yimeng Zhang, Ya Zhou, Xiaohong Li, Xu Pan, Ju Bai, Yijin Chen, Zhenyang Lai, Qiang Chen, Feng Ma, Yong Don. Small-molecule α-lipoic acid targets ELK1 to balance human neutrophil and erythrocyte differentiation. Stem cell research & therapy. vol 15. issue 1. 2024-04-08. PMID:38589882. |
in hematopoiesis, ala (alpha lipoic acid) is reported to inhibit neutrophil lineage determination by targeting transcription factor elk1 in granulocyte-monocyte progenitors via splicing factor sf3b1. |
2024-04-08 |
2024-04-11 |
human |
| Hatice Şiyzen Çoban, Nazlı Çil, Elif Önder, Gülçin Abban Met. Anti-cancer effects of alpha lipoic acid, cisplatin and paclitaxel combination in the OVCAR-3 ovarian adenocarcinoma cell line. Molecular biology reports. vol 51. issue 1. 2024-04-05. PMID:38578399. |
one of the major challenges in treating ovarian cancer with chemotherapy is managing the resistance developed by cancer cells to drugs, while also minimizing the side effects caused by these agents in the present study, we aimed to examine the effects of a combination of alpha lipoic acid (ala), with cisplatin and paclitaxel in ovarian cancer(ovcar-3). |
2024-04-05 |
2024-04-07 |
Not clear |
| Ramanachary Namoju, Kavitha N Chilak. Protective effect of alpha‑lipoic acid against in utero cytarabine exposure-induced hepatotoxicity in rat female neonates. Naunyn-Schmiedeberg's archives of pharmacology. 2024-03-09. PMID:38459988. |
alpha lipoic acid (ala) is a natural antioxidant reported to offer protection against hepatotoxicity induced by various pathological conditions, drugs, or chemicals. |
2024-03-09 |
2024-03-12 |
rat |
| Madeline C Tompach, Charlotte K Gridley, Sida Li, John M Clark, Yeonhwa Park, Alicia R Timme-Larag. Comparing the effects of developmental exposure to alpha lipoic acid (ALA) and perfluorooctanesulfonic acid (PFOS) in zebrafish (Danio rerio). Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2024-03-03. PMID:38432440. |
comparing the effects of developmental exposure to alpha lipoic acid (ala) and perfluorooctanesulfonic acid (pfos) in zebrafish (danio rerio). |
2024-03-03 |
2024-03-06 |
zebrafish |
| Madeline C Tompach, Charlotte K Gridley, Sida Li, John M Clark, Yeonhwa Park, Alicia R Timme-Larag. Comparing the effects of developmental exposure to alpha lipoic acid (ALA) and perfluorooctanesulfonic acid (PFOS) in zebrafish (Danio rerio). Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2024-03-03. PMID:38432440. |
alpha lipoic acid (ala) is a dietary supplement that has been used to treat a wide range of diseases including obesity and diabetes and have lipid-lowering effects, making it a potential candidate for mitigating dyslipidemia resulting from exposures to the per- and polyfluoroalkyl substance (pfas) family member perfluorooctanesulfonic acid (pfos). |
2024-03-03 |
2024-03-06 |
zebrafish |
| Alexandros Tsoupras, Donal Moran, Katie Shiels, Sushanta Kumar Saha, Ibrahim M Abu-Reidah, Raymond H Thomas, Shane Redfer. Enrichment of Whole-Grain Breads with Food-Grade Extracted Apple Pomace Bioactives Enhanced Their Anti-Inflammatory, Antithrombotic and Anti-Oxidant Functional Properties. Antioxidants (Basel, Switzerland). vol 13. issue 2. 2024-02-24. PMID:38397823. |
structural analysis by lcms showed that the pl-bioactives from all these sources (ap and the bio-functional breads) are rich in bioactive unsaturated fatty acids (ufa), especially in the omega-9 oleic acid (oa; 18:1n9), the omega-3 alpha linolenic acid (ala; 18:n3) and the omega-6 linoleic acid (la; 18:2n6), which further supports their strong anti-inflammatory and antithrombotic properties. |
2024-02-24 |
2024-02-26 |
human |
| Mario B Prado, Karen Joy B Adia. Ranking Alpha Lipoic Acid and Gamma Linolenic Acid in Terms of Efficacy and Safety in the Management of Adults With Diabetic Peripheral Neuropathy: A Systematic Review and Network Meta-analysis. Canadian journal of diabetes. 2024-02-13. PMID:38295879. |
the purpose of this work was to summarize the available evidence about the efficacy and safety of alpha lipoic acid (ala) and gamma linolenic acid (gla) in the management of dn. |
2024-02-13 |
2024-02-15 |
Not clear |