| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Zeina Halabi, Christelle El Helou, Hassan Al Balushi, Melissa Gittinger, Alaina R Steck, Adel Kaakour, Ali Abu-Alfa, Tharwat El Zahra. Alpha Lipoic Acid Toxicity: The First Reported Mortality in an Adult Patient After Multiorgan Failure. The Journal of emergency medicine. 2023-02-22. PMID:36806430. |
alpha lipoic acid (ala) is an anti-oxidant found in many over-the-counter supplements and is used in treatments for diabetes, hypertension, and obesity. |
2023-02-22 |
2023-08-14 |
Not clear |
| Jian Zhang, Yuan Zhao, Yidan Zhang, Ya Gao, Shuyue Li, Cui Chang, Xuan Gao, Jingru Zhao, Guofeng Yan. Alpha lipoic acid treatment in late middle age improves cognitive function: proteomic analysis of the protective mechanisms in the hippocampus. Neuroscience letters. 2023-01-28. PMID:36708754. |
alpha lipoic acid (ala), a powerful antioxidant, has the potential to relieve age-related cognitive impairment and neurodegenerative disease. |
2023-01-28 |
2023-08-14 |
mouse |
| Hasan Türkez, Özge Çağlar Yıldırım, Sena Öner, Abdurrahim Kadı, Abdulkadir Mete, Mehmet Enes Arslan, İrfan Oğuz Şahin, Ömer Erkan Yapça, Adil Mardinoğl. Lipoic Acid Conjugated Boron Hybrids Enhance Wound Healing and Antimicrobial Processes. Pharmaceutics. vol 15. issue 1. 2023-01-21. PMID:36678778. |
here, we design alpha lipoic acid (ala) conjugated hexagonal boron nitride (hbn) and boron carbide (b |
2023-01-21 |
2023-08-14 |
Not clear |
| Kaio Murilo Monteiro Espíndola, Everton Luiz Pompeu Varela, Rosyana de Fátima Vieira de Albuquerque, Rosiane Araújo Figueiredo, Sávio Monteiro Dos Santos, Nívea Silva Malcher, Pamela Suelen da S Seabra, Andréia do Nascimento Fonseca, Karla Marcely de Azevedo Sousa, Susan Beatriz Batista de Oliveira, Agnaldo da Silva Carneiro, Michael D Coleman, Marta Chagas Monteir. Alpha-Lipoic Acid and Its Enantiomers Prevent Methemoglobin Formation and DNA Damage Induced by Dapsone Hydroxylamine: Molecular Mechanism and Antioxidant Action. International journal of molecular sciences. vol 24. issue 1. 2023-01-08. PMID:36613503. |
in this study, we aim to evaluate the protective effect of racemic alpha lipoic acid (ala) and its enantiomers on methemoglobin induction. |
2023-01-08 |
2023-08-14 |
cat |
| Jayant Patwa, Ashima Thakur, Swaran Jeet Singh Flor. Alpha Lipoic Acid and Monoisoamyl-DMSA Combined Treatment Ameliorates Copper-Induced Neurobehavioral Deficits, Oxidative Stress, and Inflammation. Toxics. vol 10. issue 12. 2022-12-22. PMID:36548551. |
in the present study, we investigated the effects of the combined administration of monoisoamyl 2, 3-dimercaptosuccinic acid (miadmsa), which is a new chelator, and alpha lipoic acid (ala) and an antioxidant that is made naturally in the body and is also found in foods, against cu-induced oxidative stress in rats. |
2022-12-22 |
2023-08-14 |
rat |
| Alicia Leikin-Frenkel, Michal Schnaider Beeri, Itzik Coope. How Alpha Linolenic Acid May Sustain Blood-Brain Barrier Integrity and Boost Brain Resilience against Alzheimer's Disease. Nutrients. vol 14. issue 23. 2022-12-11. PMID:36501121. |
interestingly, alpha linolenic acid (ala), the precursor of the majoritarian brain component docosahexaenoic acid (dha), emerges as a potential novel brain savior, acting via bbb functional improvements, and this may be primarily relevant to apoe4 carriers. |
2022-12-11 |
2023-08-14 |
Not clear |
| Noha M Khoder, Hussein G Sawie, Hayat M Sharada, Eman N Hosny, Yasser A Khadrawy, Mohga S Abdull. Metformin and alpha lipoic acid ameliorate hypothyroidism and its complications in adult male rats. Journal of diabetes and metabolic disorders. vol 21. issue 2. 2022-11-21. PMID:36404819. |
the current study evaluates the effect of metformin (met) and /or alpha lipoic acid (ala) on hypothyroidism and its adverse effects on the cardiac, renal, and, hepatic functions in rats. |
2022-11-21 |
2023-08-14 |
rat |
| Mohamed A Alfaleh, Omar Fahmy, Mohammed W Al-Rabia, Mohammed A S Abourehab, Osama A A Ahmed, Usama A Fahmy, Helal H Alsulimani, Shaimaa M Badr-Eldin, Hibah M Aldawsari, Bander M Aldhabi, Awaad S Alharbi, Nabil A Alhakam. Hybrid nanoparticulate system of Fluvastatin loaded phospholipid, alpha lipoic acid and melittin for the management of colon cancer. Scientific reports. vol 12. issue 1. 2022-11-14. PMID:36376469. |
the aim of this work was to investigate the combination of flv with mel loaded hybrid formula of phospholipid (pl) with alpha lipoic acid (ala) nanoparticles to maximize anticancer tendencies. |
2022-11-14 |
2023-08-14 |
Not clear |
| Rahil Jannatifar, Elham Asa, Seyedeh Saeideh Sahraei, Atefeh Verdi, Hamid Piroozmanes. N-acetyl-l-cysteine and alpha lipoic acid are protective supplement on human sperm parameters in cryopreservation of asthenoteratozoospermia patients. Andrologia. 2022-11-02. PMID:36321244. |
the aim of this study is to evaluate the beneficial effects of n-acetyl-cysteine (nac), alpha lipoic acid (ala) and combination of nac + ala supplement in freezing medium on sperm structural and functional in asthenoteratozoospermia patients. |
2022-11-02 |
2023-08-14 |
human |
| Mahak Singh, R Talimoa Mollier, R N Patton, Nungshitula Pongener, L J Bordoloi, Rakesh Kumar, Rahul Katiyar, M H Khan, D J Rajkhowa, V K Mishr. Linseed oil in boar's diet improved in-vivo fertility and antioxidant status. Reproduction in domestic animals = Zuchthygiene. 2022-09-07. PMID:36069223. |
linseed oil feeding (p < 0.05) increased the proportion of alpha linolenic (ala), arachidonic and docosahexaenoic (dha) fatty acids in sp. |
2022-09-07 |
2023-08-14 |
cat |
| Fabian Dieter, Carsten Esselun, Gunter P Ecker. Redox Active α-Lipoic Acid Differentially Improves Mitochondrial Dysfunction in a Cellular Model of Alzheimer and Its Control Cells. International journal of molecular sciences. vol 23. issue 16. 2022-08-26. PMID:36012451. |
alpha lipoic acid (ala) is a sulphur-containing organic compound, derived from octanoic acid, and an important cofactor for mitochondrial respiratory enzymes. |
2022-08-26 |
2023-08-14 |
Not clear |
| Alessandro D Genazzani, Christian Battipaglia, Tabatha Petrillo, Nicola Piacquadio, Fedora Ambrosetti, Melania Arnesano, Elisa Semprini, Alessandra Sponzilli, Veronica Tomatis, Tommaso Simoncin. Familial diabetes predisposes PCOS patients to insulin resistance (IR), reproductive impairment and hepatic dysfunction: effects of d-chiro inositol (DCI) and alpha lipoic acid (ALA) administration on hepatic insulin extraction (HIE) index. Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology. 2022-06-24. PMID:35748584. |
familial diabetes predisposes pcos patients to insulin resistance (ir), reproductive impairment and hepatic dysfunction: effects of d-chiro inositol (dci) and alpha lipoic acid (ala) administration on hepatic insulin extraction (hie) index. |
2022-06-24 |
2023-08-14 |
Not clear |
| Yamini Tak, Manpreet Kaur, Rajendra Kumar, Chirag Gautam, Prabhjot Singh, Harjeet Kaur, Amanpreet Kaur, Surekha Bhatia, Niraj Kumar Jha, Piyush Kumar Gupta, Ryszard Amarowic. Repurposing chia seed oil: A versatile novel functional food. Journal of food science. 2022-06-16. PMID:35708201. |
the oil is rich in with polyunsaturated fatty acids (pufas), especially, alpha linolenic acid (ala), linoleic acid (la), tocopherols, phenolic acids, vitamins, and antioxidants. |
2022-06-16 |
2023-08-14 |
Not clear |
| Rahil Jannatifar, Hamid Piroozmanesh, Seyedeh Saeideh Sahraei, Elham As. Combination of alpha lipoic acid and metformin supplement improve assisted reproductive technologies outcomes in polycystic ovary syndrome patients. Anatomy & cell biology. 2022-05-02. PMID:35501295. |
we aimed to investigating the effects of metformin (met) in combination with alpha lipoic acid (ala) on hormonal and biochemical parameters, in polycystic ovary syndrome (pcos) women undergoing intracytoplasmic sperm injection (icsi). |
2022-05-02 |
2023-08-13 |
Not clear |
| Danielle Defries, Kayla Curtis, Jay C Petkau, Shiva Shariati-Ievari, Heather Blewett, Michel Alian. Patterns of Alpha-Linolenic Acid Incorporation into Phospholipids in H4IIE Cells. The Journal of nutritional biochemistry. 2022-04-24. PMID:35461904. |
alpha linolenic acid (ala) is an 18-carbon essential fatty acid found in plant-based foods and oils. |
2022-04-24 |
2023-08-13 |
Not clear |
| Elisa Grillo Araújo, Domitilla Marchiori Sant'Anna Leal de Oliveira, Carolina Castro Martins, Cristine Miron Stefan. Efficacy of Antioxidant Supplementation to Non-Surgical Periodontal Therapy on Metabolic Control in Type 2 Diabetes Patients: A Network Meta-Analysis. Antioxidants (Basel, Switzerland). vol 11. issue 4. 2022-04-23. PMID:35453306. |
ten randomized controlled clinical trials were included, with 234 patients receiving alpha lipoic acid (ala), cranberry juice, cranberry juice enriched with omega-3, fenugreek, ginger, grape seed, lycopene, melatonin, omega-3, propolis or vitamin c supplementation to nspt, and 220 patients receiving nspt alone or with placebo. |
2022-04-23 |
2023-08-13 |
Not clear |
| Yasser A Khadrawy, Noha M Khoder, Hussein G Sawie, Hayat M Sharada, Eman N Hosny, Mohga S Abdull. The neuroprotective effect of alpha lipoic acid and/or metformin against the behavioral and neurochemical changes induced by hypothyroidism in rat. Neuroendocrinology. 2022-03-30. PMID:35354137. |
the present study evaluates the neuroprotective effect of alpha lipoic acid (ala) and/or metformin (met) on the behavioral and neurochemical changes induced by hypothyroidism. |
2022-03-30 |
2023-08-13 |
rat |
| Christelle Debeissat, Maryse Avalon, Mathilde Huart, Pascale Duchez, Laura Rodriguez, Marija Vlaski-Lafarge, Zoran Ivanovic, Philippe Brunet de la Grang. Alpha Lipoic-Acid Potentiates Ex Vivo Expansion of Human Steady-State Peripheral Blood Hematopoietic Primitive Cells. Biomolecules. vol 12. issue 3. 2022-03-25. PMID:35327623. |
we investigated the effect of alpha lipoic acid (ala) on ex vivo culture of sspb cd34 positive (cd34 |
2022-03-25 |
2023-08-13 |
human |
| Victor Vitoldovich Poboinev, Vladislav Victorovich Khrustalev, Tatyana Aleksandrovna Khrustaleva, Tihon Evgenyevich Kasko, Vadim Dmitrievich Popko. The PentUnFOLD algorithm as a tool to distinguish the dark and the light sides of the structural instability of proteins. Amino acids. 2022-03-16. PMID:35294674. |
among other tendencies we have found that regions of both alpha helices and beta strands that can turn into the disordered state are relatively enriched in residues of ala, met, asp, and lys, while regions of both alpha helices and beta strands that can turn into random coil are relatively enriched in hydrophilic residues, and cys, pro, and gly. |
2022-03-16 |
2023-08-13 |
Not clear |
| Kevser Tanbek, Elif Ozerol, Umit Yilmaz, Nesibe Yilmaz, Mehmet Gul, Cemil Cola. Alpha Lipoic Acid Decreases Neuronal Damage on Brain Tissue of STZ-Induced Diabetic Rats. Physiology & behavior. 2022-02-08. PMID:35131301. |
the aim of this study was to evaluate the biochemical, histological and physiological effects of alpha lipoic acid (ala) against brain tissue damage caused by diabetes. |
2022-02-08 |
2023-08-13 |
rat |