| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Neslihan Pınar, Gökhan Çakırca, Sibel Hakverdi, Mahir Kapla. Protective effect of alpha lipoic acid on cisplatin induced hepatotoxicity in rats. Biotechnic & histochemistry : official publication of the Biological Stain Commission. vol 95. issue 3. 2021-01-04. PMID:31687838. |
we investigated the protective effect of alpha lipoic acid (ala) against cisplatin (cis) induced hepatotoxicity in rats. |
2021-01-04 |
2023-08-13 |
rat |
| b' Feyyaz \\xc3\\x96zel, M\\xc3\\xbcge Kiray, Asl\\xc4\\xb1 G\\xc3\\xb6ker, Selma Aydemir, Serap Cilaker M\\xc4\\xb1c\\xc4\\xb1l\\xc4\\xb. Protective effect of alpha lipoic acid on 4-vinylcyclohexene diepoxide induced primary ovarian failure in female rats. Taiwanese journal of obstetrics & gynecology. vol 59. issue 2. 2020-12-14. PMID:32127153.' |
the effects of alpha lipoic acid (ala) and its possible mechanisms in treating primary ovarian failure (pof) model was studied with 4 vinylcyclohexene diepoxide (vcd). |
2020-12-14 |
2023-08-13 |
rat |
| Tejas M Maheshwari, Anurag Sharma, Bhagwani Bai Maheshwar. Insulin autoimmune syndrome: A rare cause of hypoglycemia. Journal of family medicine and primary care. vol 9. issue 9. 2020-11-20. PMID:33209842. |
recently a compound called alpha lipoic acid (ala) has been associated with an increased risk of developing ias. |
2020-11-20 |
2023-08-13 |
Not clear |
| Ella J Baker, Carina A Valenzuela, Camila O De Souza, Parveen Yaqoob, Elizabeth A Miles, Philip C Calde. Comparative anti-inflammatory effects of plant- and marine-derived omega-3 fatty acids explored in an endothelial cell line. Biochimica et biophysica acta. Molecular and cell biology of lipids. vol 1865. issue 6. 2020-10-27. PMID:32058033. |
plant-derived alpha linolenic acid (ala) and stearidonic acid (sda) could provide sustainable land-based alternatives, but their functionality is underexplored. |
2020-10-27 |
2023-08-13 |
Not clear |
| Feng Shen, Haoquan Zhong, Wenjiao Ge, Junli Ren, Xiaohui Wan. Quercetin/chitosan-graft-alpha lipoic acid micelles: A versatile antioxidant water dispersion with high stability. Carbohydrate polymers. vol 234. 2020-10-21. PMID:32070546. |
in this paper, a natural antioxidant alpha lipoic acid (ala) was grafted onto chitosan (cs) to synthesize a novel graft polymer (cs-graft-ala). |
2020-10-21 |
2023-08-13 |
Not clear |
| Masatoshi Honjo, Okuhara Yasuhide, Masayoshi Yamada, Sei Higuchi, Kenji Mishima, Tanjina Sharmin, Taku Michael Aida, Takafumi Kato, Makoto Misumi, Tadashi Suetsugu, Hideaki Orii, Keiichi Irie, Kazunori Sano, Kenichi Mishima, Tomomitsu Satho, Takunori Harad. Characterization and pharmacokinetic evaluation of microcomposite particles of alpha lipoic acid/hydrogenated colza oil obtained in supercritical carbon dioxide. Pharmaceutical development and technology. vol 25. issue 3. 2020-10-15. PMID:30632427. |
the work reported here is an extension of our previous findings in which supercritical composite particles (scp) of alpha lipoic acid (ala) masked with hydrogenated colza oil (hco) named as ala/hco/scp were obtained by the modified particles from gas-saturated solutions (pgss) process in supercritical carbon dioxide in order to obscure the unpleasant taste and odor of ala. |
2020-10-15 |
2023-08-13 |
Not clear |
| David L William. Effect of Oral Alpha Lipoic Acid in Preventing the Genesis of Canine Diabetic Cataract: A Preliminary Study. Veterinary sciences. vol 4. issue 1. 2020-10-01. PMID:29056677. |
a topical ar inhibitor has been shown to have this effect, as has the commercially available neutraceutical ocuglo, containing the ar inhibitor alpha lipoic acid (ala) together with other plant-based antioxidants. |
2020-10-01 |
2023-08-13 |
human |
| Anastasia V Shindyapina, Tatiana V Komarova, Ekaterina V Sheshukova, Natalia M Ershova, Vadim N Tashlitsky, Alexander V Kurkin, Ildar R Yusupov, Garik V Mkrtchyan, Murat Y Shagidulin, Yuri L Dorokho. The Antioxidant Cofactor Alpha-Lipoic Acid May Control Endogenous Formaldehyde Metabolism in Mammals. Frontiers in neuroscience. vol 11. 2020-10-01. PMID:29249928. |
it has been shown that 1,2-dithiolane-3-pentanoic acid or alpha lipoic acid (ala), a naturally occurring dithiol and antioxidant cofactor of mitochondrial α-ketoacid dehydrogenases, increases glutathione (gsh) content and fa metabolism by mitochondrial aldehyde dehydrogenase 2 (aldh2) thus manifests a therapeutic potential beyond its antioxidant property. |
2020-10-01 |
2023-08-13 |
human |
| Elif Erdem Guzel, Nalan Kaya, Gonca Ozan, Ahmet Tektemur, Durrin Ozlem Dabak, Ibrahim Enver Oza. The investigation of effect of alpha lipoic acid against damage on neonatal rat lung to maternal tobacco smoke exposure. Toxicology reports. vol 5. 2020-10-01. PMID:29984187. |
spraque-dawley female rats were divided into four groups: control, tobacco smoke (ts), tobacco smoke + alpha lipoic acid (ts + ala) and alpha lipoic acid (ala). |
2020-10-01 |
2023-08-13 |
rat |
| Senay Topsakal, Ozlem Ozmen, Rahime Aslankoc, Demet Hancer Aydemi. Pancreatic damage induced by cigarette smoke: the specific pathological effects of cigarette smoke in the rat model. Toxicology research. vol 5. issue 3. 2020-10-01. PMID:30090402. |
this study aimed to evaluate the oxidative stress status, biochemical, pathological and immunohistochemical findings of rats exposed to cigarette smoke, pathogenesis of smoking related pancreatic damage and usability of alpha lipoic acid (ala) for amelioration of cigarette smoking induced harmful effects on rat pancreas. |
2020-10-01 |
2023-08-13 |
rat |
| H Usta Atmaca, F Akba. THE EFFECT OF SHORT TERM ALPHA LIPOIC ACID ADMINISTRATION ON ADIPONECTIN AND BODY WEIGHT IN TYPE 2 DIABETES MELLITUS PATIENTS. Acta endocrinologica (Bucharest, Romania : 2005). vol 13. issue 4. 2020-10-01. PMID:31149217. |
alpha lipoic acid (ala) acts as essential co-factor for mitochondrion respiratory enzymes. |
2020-10-01 |
2023-08-13 |
Not clear |
| Mahsa Kaveh, Naeima Eftekhar, Mohammad Hossein Boskabad. The effect of alpha linolenic acid on tracheal responsiveness, lung inflammation, and immune markers in sensitized rats. Iranian journal of basic medical sciences. vol 22. issue 3. 2020-10-01. PMID:31156785. |
the effects of alpha linolenic acid (ala) on tracheal responsiveness (tr), total protein (tp), phospholipase a2 (pla2), immunoglobulin e (ige), interleukin 4 (il-4), interferon gamma (inf-γ) level and inf-γ/il4 ratio in bronchoalveolar lavage fluid (balf) of sensitized rats were examined. |
2020-10-01 |
2023-08-13 |
rat |
| Reza Tabrizi, Afshin Borhani-Haghighi, Naghmeh Mirhosseini, Kamran B Lankarani, Ahmad Naghibzadeh-Tahami, Maryam Akbari, Seyed Taghi Heydari, Mojgan Sangari, Fariba Kolahdooz, Fariba Raygan, Zatollah Asem. The effects of alpha-lipoic acid supplementation on fasting glucose and lipid profiles among patients with stroke: a systematic review and meta-analysis of randomized controlled trials. Journal of diabetes and metabolic disorders. vol 18. issue 2. 2020-10-01. PMID:31890685. |
alpha lipoic acid (ala), with its antioxidant properties, might improve metabolic status of patients, though current evidence is still inclusive. |
2020-10-01 |
2023-08-13 |
Not clear |
| Daniel Sarezky, Aaishah R Raquib, Joshua L Dunaief, Benjamin J Ki. Tolerability in the elderly population of high-dose alpha lipoic acid: a potential antioxidant therapy for the eye. Clinical ophthalmology (Auckland, N.Z.). vol 10. 2020-09-30. PMID:27729766. |
alpha lipoic acid (ala) is an antioxidant and iron-chelating supplement that has potential benefits for geographic atrophy in dry age-related macular degeneration as well as other eye diseases. |
2020-09-30 |
2023-08-13 |
Not clear |
| S Siva Kumar, B V Balasubramanyam, K Jayaraj Rao, P Heartwin Amala Dhas, B Surendra Nat. Effect of flaxseed oil and flour on sensory, physicochemical and fatty acid profile of the fruit yoghurt. Journal of food science and technology. vol 54. issue 2. 2020-09-30. PMID:28242936. |
the fatty acid analysis revealed that alpha linolenic acid (ala) content increased from 0.45% of ala in control sample to 22.80% of ala in the final product. |
2020-09-30 |
2023-08-13 |
Not clear |
| Shilpi Dixit, Pushpa Dhar, Raj D Mehr. Alpha lipoic acid (ALA) modulates expression of apoptosis associated proteins in hippocampus of rats exposed during postnatal period to sodium arsenite (NaAsO Toxicology reports. vol 2. 2020-09-30. PMID:28962340. |
alpha lipoic acid (ala) modulates expression of apoptosis associated proteins in hippocampus of rats exposed during postnatal period to sodium arsenite (naaso the present study focused on the role of exogenous alpha lipoic acid (ala) in amelioration of inorganic arsenic ( |
2020-09-30 |
2023-08-13 |
rat |
| Reda Hassan Elbakary, Sadika Mohamed Tawfik, Rabab Mohamed Ame. Evaluation of the Possible Protective Effect of Alpha Lipoic Acid on Testicular Toxicity Induced by Polychlorinated Biphenyl in Adult Albino Rats: A Histological Study. Journal of microscopy and ultrastructure. vol 8. issue 2. 2020-09-28. PMID:32766117. |
alpha lipoic acid (ala) is an antioxidant substance normally present in mitochondria as a coenzyme. |
2020-09-28 |
2023-08-13 |
rat |
| Wenwen Lei, Yang Gao, Shiruo Hu, Dongying Liu, Qiu Che. Effects of inositol and alpha lipoic acid combination for polycystic ovary syndrome: A protocol for systematic review and meta-analysis. Medicine. vol 99. issue 30. 2020-08-21. PMID:32791663. |
several small studies have indicated that inositol and alpha lipoic acid (ala) supplementation can ameliorate the outcomes in terms of menstrual cyclicity, ovulation and hyperinsulinemia in pcos women. |
2020-08-21 |
2023-08-13 |
Not clear |
| Mehran Rahimlou, Maryam Asadi, Nasrin Banaei Jahromi, Anahita Mansoor. Alpha-lipoic acid (ALA) supplementation effect on glycemic and inflammatory biomarkers: A Systematic Review and meta- analysis. Clinical nutrition ESPEN. vol 32. 2020-08-04. PMID:31221283. |
several randomized clinical trials (rcts) have investigated the effect of alpha - lipoic acid (ala) supplementation on metabolic parameters, with conflicting results. |
2020-08-04 |
2023-08-13 |
Not clear |
| Dayong Xia, Xiaofu Zhai, Honglian Wang, Zhiyong Chen, Chuanjing Fu, Meihua Zh. Alpha lipoic acid inhibits oxidative stress-induced apoptosis by modulating of Nrf2 signalling pathway after traumatic brain injury. Journal of cellular and molecular medicine. vol 23. issue 6. 2020-07-31. PMID:30989783. |
alpha lipoic acid (ala) is a powerful antioxidant which has been widely used in the treatment of different system diseases, such as cardiovascular and cerebrovascular diseases. |
2020-07-31 |
2023-08-13 |
rat |