| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mahdi Vajdi, Nooshin Noshadi, Shirin Hassanizadeh, Atefeh Bonyadian, Hooria Seyedhosseini-Ghaheh, Gholamreza Askar. The effects of alpha lipoic acid (ALA) supplementation on blood pressure in adults: a GRADE-assessed systematic review and dose-response meta-analysis of randomized controlled trials. Frontiers in cardiovascular medicine. vol 10. 2023-11-09. PMID:37942070. |
the effects of alpha lipoic acid (ala) supplementation on blood pressure in adults: a grade-assessed systematic review and dose-response meta-analysis of randomized controlled trials. |
2023-11-09 |
2023-11-20 |
Not clear |
| Mahdi Vajdi, Nooshin Noshadi, Shirin Hassanizadeh, Atefeh Bonyadian, Hooria Seyedhosseini-Ghaheh, Gholamreza Askar. The effects of alpha lipoic acid (ALA) supplementation on blood pressure in adults: a GRADE-assessed systematic review and dose-response meta-analysis of randomized controlled trials. Frontiers in cardiovascular medicine. vol 10. 2023-11-09. PMID:37942070. |
there have been various clinical studies on the effect of alpha lipoic acid (ala) supplementation on blood pressure (bp), but the findings from these are contradictory. |
2023-11-09 |
2023-11-20 |
Not clear |
| Walaa El-Houseiny, Ahmed H Arisha, Mohamed M M Metwally, Abdel-Wahab A Abdel-Warith, Elsayed M Younis, Simon J Davies, Bayan A Hassan, Yasmina M Abd-Elhaki. Alpha-lipoic acid suppresses gibberellic acid nephrotoxicity in Nile tilapia (Oreochromis niloticus) via modulating oxidative stress, inflammation, cytokine production, and apoptosis. Pesticide biochemistry and physiology. vol 196. 2023-11-09. PMID:37945227. |
recently, alpha lipoic acid (ala) has drawn much interest due to its antioxidant properties. |
2023-11-09 |
2023-11-20 |
cat |
| Wei Wang, Dandan Zhang, Lei Sun, Zihao Zhang, Yiwen Zhang, Yongteng Zhang, Yunhai Zhang, Mianqun Zhan. Alpha-lipoic acid supplementation reverses the declining quality of oocytes exposed to cyclophosphamide. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2023-10-14. PMID:37838213. |
as a cofactor of mitochondrial multienzyme complexes, alpha lipoic acid (ala) is well known for its antioxidant characteristics, which operate directly on the scavenging of reactive oxygen species (ros) and indirectly on the intracellular recycling of other antioxidants. |
2023-10-14 |
2023-11-08 |
Not clear |
| Mohammed Abdullah Ali, Ansam Naji Alhassani, Badraldin Kareem Hama. Impacts of trelagliptin and remogliflozin alone and in combination with Alpha Lipoic Acid on cardiac function in streptozotocin-induced diabetes mellitus in rats. Cellular and molecular biology (Noisy-le-Grand, France). vol 69. issue 9. 2023-10-09. PMID:37807327. |
this study investigated the effects of trelagliptin and remogliflozin, alone and in combination with alpha lipoic acid (ala), on cardiac biomarkers in diabetic cardiomyopathy (dcm). |
2023-10-09 |
2023-10-15 |
rat |
| Elif Önder, Nazlı Çil, Mücahit Seçme, Gülçin Abban Met. Effect of Alpha Lipoic Acid on Epithelial Mesenchymal Transition in SKOV-3 Cells. Gene. 2023-10-09. PMID:37813206. |
it has been suggested that alpha lipoic acid (ala), a natural antioxidant lipophilic compound, reduces the oxidative stress by causing apoptosis and inhibition of proliferation of cell in cancer cells. |
2023-10-09 |
2023-10-15 |
Not clear |
| Anja Divković, Zinaida Karasalihović, Ivana Rumora Samarin, Damir Sabitović, Kristina Radić, Nikolina Golub, Lovorka Vujić, Marija Grdić Rajković, Dubravka Vitali Čep. Effect of Alpha Lipoic Acid Supplementation on Oxidative Stress and Lipid Parameters in Women Diagnosed with Low-Grade Squamous Intraepithelial Lesions (LSILs): A Double-Blind, Randomized, Placebo-Controlled Trial. Antioxidants (Basel, Switzerland). vol 12. issue 9. 2023-09-28. PMID:37759972. |
limited scientific evidence shows that alpha lipoic acid (ala) can induce regression rates of low-grade squamous intraepithelial lesions (lsils), but the mechanisms of these effects have not been elucidated. |
2023-09-28 |
2023-10-07 |
human |
| Eligio Parente, Giulia Colannino, Gabriele Bilotta, Maria Salomé Bezerra Espinola, Sara Proietti, Mario Montanino Oliva, Isabella Neri, Cesare Aragona, Vittorio Unfe. Effect of Oral High Molecular Weight Hyaluronic Acid (HMWHA), Alpha Lipoic Acid (ALA), Magnesium, Vitamin B6 and Vitamin D Supplementation in Pregnant Women: A Retrospective Observational Pilot Study. Clinics and practice. vol 13. issue 5. 2023-09-22. PMID:37736936. |
effect of oral high molecular weight hyaluronic acid (hmwha), alpha lipoic acid (ala), magnesium, vitamin b6 and vitamin d supplementation in pregnant women: a retrospective observational pilot study. |
2023-09-22 |
2023-10-07 |
Not clear |
| Eligio Parente, Giulia Colannino, Gabriele Bilotta, Maria Salomé Bezerra Espinola, Sara Proietti, Mario Montanino Oliva, Isabella Neri, Cesare Aragona, Vittorio Unfe. Effect of Oral High Molecular Weight Hyaluronic Acid (HMWHA), Alpha Lipoic Acid (ALA), Magnesium, Vitamin B6 and Vitamin D Supplementation in Pregnant Women: A Retrospective Observational Pilot Study. Clinics and practice. vol 13. issue 5. 2023-09-22. PMID:37736936. |
the aim of this retrospective pilot study is to evidence whether the oral supplementation with high molecular weight hyaluronic acid (hmwha), in association with alpha lipoic acid (ala), magnesium, vitamin b6 and vitamin d, in pregnant women, could reduce adverse effects, such as ptb, pelvic pain, contraction and hospitalization. |
2023-09-22 |
2023-10-07 |
Not clear |
| Lata Singh, Shari Atilano, Marilyn Chwa, Mithalesh K Singh, Mustafa Ozgul, Anthony Nesburn, M Cristina Kenne. Using Human 'Personalized' Cybrids to Identify Drugs/Agents That Can Regulate Chronic Lymphoblastic Leukemia Mitochondrial Dysfunction. International journal of molecular sciences. vol 24. issue 13. 2023-07-14. PMID:37446202. |
the nl and cll cybrids were treated with ibrutinib (ibr-10 μm), mitochondrial-targeted nutraceuticals such as alpha lipoic acid (ala-1 mm), amla (aml-300 μg), melatonin (mel-1 mm), resveratrol (res-100 μm) alone, or a combination of ibrutinib with nutraceuticals (ibr + ala, ibr + aml, ibr + mel, or ibr + res) for 48 h. mtt (3-(4,5-dimethylthiazolyl-2)-2,5-diphenyltetrazoliumbromide), h2dcfda(2',7' dichlorodihydrofluorescein diacetate), and jc1 assays were used to measure the cellular metabolism, intracellular ros levels, and mitochondrial membrane potential (∆ψm), respectively. |
2023-07-14 |
2023-08-14 |
human |
| Qian Zheng, Pengfei Ma, Pan Yang, Suzhen Zhai, Meina He, Xiangming Zhang, Qiuxia Tu, Ling Jiao, Lan Ye, Zhanhui Feng, Chunlin Zhan. Alpha lipoic acid ameliorates motor deficits by inhibiting ferroptosis in Parkinson's disease. Neuroscience letters. 2023-06-12. PMID:37308056. |
as an antioxidant and iron chelating agent, alpha lipoic acid (ala) has a neuroprotective effect on pd; however, the influence of ala on ferroptosis in pd remains unclear. |
2023-06-12 |
2023-08-14 |
Not clear |
| Edward J Calabrese, Evgenios Agathokleous, Gaurav Dhawan, Rachna Kapoor, Vittorio Calabres. Protective effects of alpha lipoic acid (ALA) are mediated by hormetic mechanisms. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2023-05-11. PMID:37169059. |
protective effects of alpha lipoic acid (ala) are mediated by hormetic mechanisms. |
2023-05-11 |
2023-08-14 |
Not clear |
| Edward J Calabrese, Evgenios Agathokleous, Gaurav Dhawan, Rachna Kapoor, Vittorio Calabres. Protective effects of alpha lipoic acid (ALA) are mediated by hormetic mechanisms. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2023-05-11. PMID:37169059. |
the endogenous and dietary agent, alpha lipoic acid (ala) is evaluated for its capacity to induce a broad spectrum of adaptive responses via hormetic dose responses and their underlying mechanisms. |
2023-05-11 |
2023-08-14 |
Not clear |
| Seyed Soheil Saeedi Saravi, Nicole R Bonetti, Ana Vukolic, Daria Vdovenko, Pratintip Lee, Luca Liberale, Cristina Basso, Stefania Rizzo, Alexander Akhmedov, Thomas F Lüscher, Giovanni G Camici, Jürg H Bee. Long-term dietary n3 fatty acid prevents aging-related cardiac diastolic and vascular dysfunction. Vascular pharmacology. 2023-04-27. PMID:37105373. |
we and others reported previously on the beneficial effects of omega-3 fatty acid alpha linolenic acid (ala) on cardiovascular disorders in animal models and translational studies. |
2023-04-27 |
2023-08-14 |
Not clear |
| Ghadha Ibrahim Fouad, Kawkab A Ahme. Remyelinating activities of Carvedilol or alpha lipoic acid in the Cuprizone-Induced rat model of demyelination. International immunopharmacology. vol 118. 2023-04-07. PMID:37028277. |
alpha lipoic acid (ala) is a well-known antioxidant. |
2023-04-07 |
2023-08-14 |
rat |
| Mahbubeh Ahmadi, Seyed Ali Keshavarz, Behnood Abbas. Effects of alpha lipoic acid supplementation on serum lipid profile in patients with metabolic syndrome: A randomized, double-blind, placebo-controlled clinical trial. ARYA atherosclerosis. vol 18. issue 4. 2023-02-23. PMID:36817351. |
alpha lipoic acid (ala) is considered a strong antioxidant with anti-inflammatory properties. |
2023-02-23 |
2023-08-14 |
Not clear |
| Zeina Halabi, Christelle El Helou, Hassan Al Balushi, Melissa Gittinger, Alaina R Steck, Adel Kaakour, Ali Abu-Alfa, Tharwat El Zahra. Alpha Lipoic Acid Toxicity: The First Reported Mortality in an Adult Patient After Multiorgan Failure. The Journal of emergency medicine. 2023-02-22. PMID:36806430. |
alpha lipoic acid (ala) is an anti-oxidant found in many over-the-counter supplements and is used in treatments for diabetes, hypertension, and obesity. |
2023-02-22 |
2023-08-14 |
Not clear |
| Jian Zhang, Yuan Zhao, Yidan Zhang, Ya Gao, Shuyue Li, Cui Chang, Xuan Gao, Jingru Zhao, Guofeng Yan. Alpha lipoic acid treatment in late middle age improves cognitive function: proteomic analysis of the protective mechanisms in the hippocampus. Neuroscience letters. 2023-01-28. PMID:36708754. |
alpha lipoic acid (ala), a powerful antioxidant, has the potential to relieve age-related cognitive impairment and neurodegenerative disease. |
2023-01-28 |
2023-08-14 |
mouse |
| Hasan Türkez, Özge Çağlar Yıldırım, Sena Öner, Abdurrahim Kadı, Abdulkadir Mete, Mehmet Enes Arslan, İrfan Oğuz Şahin, Ömer Erkan Yapça, Adil Mardinoğl. Lipoic Acid Conjugated Boron Hybrids Enhance Wound Healing and Antimicrobial Processes. Pharmaceutics. vol 15. issue 1. 2023-01-21. PMID:36678778. |
here, we design alpha lipoic acid (ala) conjugated hexagonal boron nitride (hbn) and boron carbide (b |
2023-01-21 |
2023-08-14 |
Not clear |
| Kaio Murilo Monteiro Espíndola, Everton Luiz Pompeu Varela, Rosyana de Fátima Vieira de Albuquerque, Rosiane Araújo Figueiredo, Sávio Monteiro Dos Santos, Nívea Silva Malcher, Pamela Suelen da S Seabra, Andréia do Nascimento Fonseca, Karla Marcely de Azevedo Sousa, Susan Beatriz Batista de Oliveira, Agnaldo da Silva Carneiro, Michael D Coleman, Marta Chagas Monteir. Alpha-Lipoic Acid and Its Enantiomers Prevent Methemoglobin Formation and DNA Damage Induced by Dapsone Hydroxylamine: Molecular Mechanism and Antioxidant Action. International journal of molecular sciences. vol 24. issue 1. 2023-01-08. PMID:36613503. |
in this study, we aim to evaluate the protective effect of racemic alpha lipoic acid (ala) and its enantiomers on methemoglobin induction. |
2023-01-08 |
2023-08-14 |
cat |