| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Birendra Mishra, Ryan Ripperdan, Laura Ortiz, Ulrike Ludere. Very low doses of heavy oxygen ion radiation induce premature ovarian failure. Reproduction (Cambridge, England). vol 154. issue 2. 2018-04-09. PMID:28528322. |
adult female mice were irradiated with 0, 5, 30 or 50 cgy oxygen ions or 50 cgy oxygen plus dietary supplementation with the antioxidant alpha lipoic acid (ala). |
2018-04-09 |
2023-08-13 |
mouse |
| Hossein Hejr, Majid Ghareghani, Kazem Zibara, Maryam Ghafari, Farzad Sadri, Zinab Salehpour, Azadeh Hamedi, Koresh Negintaji, Hassan Azari, Amir Ghanbar. The ratio of 1/3 linoleic acid to alpha linolenic acid is optimal for oligodendrogenesis of embryonic neural stem cells. Neuroscience letters. vol 651. 2018-03-26. PMID:28504119. |
in this study, we investigated the effect of various concentrations and ratios of linoleic acid (la) and alpha linolenic acid (ala), which belong respectively to omega-6 and omega-3 pufas, on the proliferation and differentiation of enscs.results showed that low (25 and 50μm) or high (100 and 200μm) concentrations of ala, but not la, and the ratio of 1:3 of la/ala significantly increased neurospheres size, frequency and cell numbers, in comparison to controls. |
2018-03-26 |
2023-08-13 |
Not clear |
| Ruixing Liu, Yanling Wang, Mingliang Pu, Jie Ga. Effect of alpha lipoic acid on retinal ganglion cell survival in an optic nerve crush model. Molecular vision. vol 22. 2018-01-15. PMID:27703307. |
this study was conducted to determine whether alpha lipoic acid (ala) promotes the survival of retinal ganglion cells (rgcs) in a rat model of optic nerve crush (onc) injury and to investigate the neuroprotective mechanisms of ala in the retina in this onc injury model. |
2018-01-15 |
2023-08-13 |
rat |
| El-Sayed M El-Sayed, Ahmed M Mansour, Waleed S El-Saw. Alpha lipoic acid prevents doxorubicin-induced nephrotoxicity by mitigation of oxidative stress, inflammation, and apoptosis in rats. Journal of biochemical and molecular toxicology. vol 31. issue 9. 2018-01-02. PMID:28598563. |
this study aimed to evaluate the protective effects of alpha lipoic acid (ala) against doxorubicin (dox)-induced nephrotoxicity in rats. |
2018-01-02 |
2023-08-13 |
rat |
| Alexandre Pinel, Elodie Pitois, Jean-Paul Rigaudiere, Chrystele Jouve, Sarah De Saint-Vincent, Brigitte Laillet, Christophe Montaurier, Alain Huertas, Beatrice Morio, Frederic Cape. EPA prevents fat mass expansion and metabolic disturbances in mice fed with a Western diet. Journal of lipid research. vol 57. issue 8. 2017-09-05. PMID:27307576. |
the impact of alpha linolenic acid (ala), epa, and dha on obesity and metabolic complications was studied in mice fed a high-fat, high-sucrose (hf) diet. |
2017-09-05 |
2023-08-13 |
mouse |
| Filippo Murina, Alessandra Graziottin, Raffaele Felice, Dania Gambin. Alpha Lipoic Acid Plus Omega-3 Fatty Acids for Vestibulodynia Associated With Painful Bladder Syndrome. Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC. vol 39. issue 3. 2017-08-03. PMID:28343553. |
this study assessed the effectiveness of alpha lipoic acid (ala) plus omega-3 polyunsaturated fatty acids (n-3 pufas) in combination with amitriptyline therapy in patients with vestibulodynia/painful bladder syndrome (vbd/pbs). |
2017-08-03 |
2023-08-13 |
Not clear |
| M Costantino, C Guaraldi, D Costantin. Resolution of subchorionic hematoma and symptoms of threatened miscarriage using vaginal alpha lipoic acid or progesterone: clinical evidences. European review for medical and pharmacological sciences. vol 20. issue 8. 2017-07-24. PMID:27160142. |
alpha lipoic acid (ala) is a safe natural molecule that exerts a selective immunomodulating activity with antioxidant and anti-inflammatory properties. |
2017-07-24 |
2023-08-13 |
Not clear |
| Giovanni Monastra, Sara De Grazia, Serap Cilaker Micili, Asli Goker, Vittorio Unfe. Immunomodulatory activities of alpha lipoic acid with a special focus on its efficacy in preventing miscarriage. Expert opinion on drug delivery. vol 13. issue 12. 2017-06-05. PMID:27292272. |
alpha lipoic acid (ala) is an essential mitochondrial co-factor and, as a free molecule, it can exert multi-level immunomodulatory functions. |
2017-06-05 |
2023-08-13 |
Not clear |
| Usama A Fahmy, Bader M Aljaei. Combined strategy for suppressing breast carcinoma MCF-7 cell lines by loading simvastatin on alpha lipoic acid nanoparticles. Expert opinion on drug delivery. vol 13. issue 12. 2017-06-05. PMID:27636370. |
augmentation of simvastatin (smv) cytotoxicity in breast carcinoma cell lines mcf-7, by: improvement of cellular uptake and loading on alpha lipoic acid (ala). |
2017-06-05 |
2023-08-13 |
Not clear |
| Khairy M A Zoheir, Gamaleldin I Harisa, Ahmed A Allam, Liguo Yang, Xiang Li, Aixin Liang, Ahmed A Abd-Rabou, Abdel Halim Harrat. Effect of alpha lipoic acid on in vitro development of bovine secondary preantral follicles. Theriogenology. vol 88. 2017-05-12. PMID:27743686. |
the present study aimed to evaluate the in vitro effect of alpha lipoic acid (ala) addition to the culture medium on the development of the bovine secondary preantral follicles. |
2017-05-12 |
2023-08-13 |
cattle |
| Arif Aydın, Alpagan Mustafa Yıldırı. Effects of alpha lipoic acid on ischemia-reperfusion injury in rat hindlimb ischemia model. Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES. vol 22. issue 6. 2017-05-10. PMID:28074465. |
this study was performed to evaluate the effect of alpha lipoic acid (ala) on prevention of ischemia-reperfusion (ir) injury in rat hindlimb ischemia model. |
2017-05-10 |
2023-08-13 |
rat |
| Jing Shi, Lan Wang, Yan Lu, Yue Ji, Yaqing Wang, Ke Dong, Xiangqing Kong, Wei Su. Protective effects of seabuckthorn pulp and seed oils against radiation-induced acute intestinal injury. Journal of radiation research. vol 58. issue 1. 2017-05-08. PMID:27422938. |
palmitoleic acid (pla) and alpha linolenic acid (ala) are the predominant components of pulp oil and seed oil, respectively. |
2017-05-08 |
2023-08-13 |
mouse |
| Celestino Sardu, Gaetano Santulli, Matteo Santamaria, Michelangela Barbieri, Cosimo Sacra, Pasquale Paolisso, Fabio D'Amico, Nicola Testa, Igor Caporaso, Giuseppe Paolisso, Raffaele Marfella, Maria Rosaria Rizz. Effects of Alpha Lipoic Acid on Multiple Cytokines and Biomarkers and Recurrence of Atrial Fibrillation Within 1 Year of Catheter Ablation. The American journal of cardiology. vol 119. issue 9. 2017-04-25. PMID:28258730. |
we tested the effects of an oral antioxidant treatment (alpha lipoic acid [ala]) on af recurrence post-ca. |
2017-04-25 |
2023-08-13 |
Not clear |
| Angela Notarnicola, Giuseppe Maccagnano, Silvio Tafuri, Alessandra Fiore, Vito Pesce, Biagio Morett. Comparison of shock wave therapy and nutraceutical composed of Echinacea angustifolia, alpha lipoic acid, conjugated linoleic acid and quercetin (perinerv) in patients with carpal tunnel syndrome. International journal of immunopathology and pharmacology. vol 28. issue 2. 2017-04-04. PMID:25953494. |
many biological mechanisms can support the administration of shock wave therapy (eswt) or of alpha lipoic acid (ala) based nutraceutical, conjugated linoleic acid (gla), anti-oxidants and echinacea angustifolia for cts. |
2017-04-04 |
2023-08-13 |
Not clear |
| Özay Güleş, Ülker Ere. Protective role of alpha lipoic acid against polychlorobiphenyl (Aroclor 1254)-induced testicular toxicity in rats. Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie. vol 57. issue 2. 2017-04-03. PMID:27516018. |
the present study was aimed to investigate the antioxidant, biochemical, and histological effects of alpha lipoic acid (ala) on polychlorinated biphenyl (pcb)-induced testicular toxicity in male rats. |
2017-04-03 |
2023-08-13 |
rat |
| Senay Topsakal, Ozlem Ozmen, Fatma Nihan Cankara, Sukriye Yesilot, Dilek Bayram, Nilüfer Genç Özdamar, Sümeyra Kaya. Alpha lipoic acid attenuates high-fructose-induced pancreatic toxicity. Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.]. vol 16. issue 3. 2017-03-31. PMID:27025195. |
the goal of the study was to investigate pancreatic damage induced by chronic hfcs consumption and the protective effects of alpha lipoic acid (ala) on pancreatic cells. |
2017-03-31 |
2023-08-13 |
Not clear |
| Merve Alpay, Begum Yurdakok-Dikmen, Gorkem Kismali, Tevhide Se. Antileukemic effects of piperlongumine and alpha lipoic acid combination on Jurkat, MEC1 and NB4 cells in vitro. Journal of cancer research and therapeutics. vol 12. issue 2. 2017-03-16. PMID:27461609. |
this research indicated to evaluate the effects of piperlongumine (pl), a biologically active alkaloid, and alpha lipoic acid (ala), a naturally occurring cofactor existed in multienzyme complexes regulating metabolism on leukemia cells. |
2017-03-16 |
2023-08-13 |
Not clear |
| Kenji Mishima, Masatoshi Honjo, Tanjina Sharmin, Shota Ito, Ryo Kawakami, Takafumi Kato, Makoto Misumi, Tadashi Suetsugu, Hideaki Orii, Hiroyuki Kawano, Keiichi Irie, Kazunori Sano, Kenichi Mishima, Takunori Harada, Mikio Ouch. Gas-saturated solution process to obtain microcomposite particles of alpha lipoic acid/hydrogenated colza oil in supercritical carbon dioxide. Pharmaceutical development and technology. vol 21. issue 6. 2017-03-13. PMID:26024240. |
alpha lipoic acid (ala), an active substance in anti-aging products and dietary supplements, need to be masked with an edible polymer to obscure its unpleasant taste. |
2017-03-13 |
2023-08-13 |
Not clear |
| D A Seyit, E Degirmenci, A Oguzhanogl. Evaluation of Electrophysiological Effects of Melatonin and Alpha Lipoic Acid in Rats with Streptozotocine Induced Diabetic Neuropathy. Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association. vol 124. issue 5. 2017-03-10. PMID:27219687. |
there are many studies in which biological ingredients, such as alpha lipoic acid (ala), that may inhibit or reduce the generation of diabetic neuropathy were investigated. |
2017-03-10 |
2023-08-13 |
rat |
| Shinichiro Saito, Ikuo Fukuhara, Noriko Osaki, Haruo Nakamura, Yoshihisa Katsurag. Consumption of alpha-Linolenic Acid-enriched Diacylglycerol Reduces Visceral Fat Area in Overweight and Obese Subjects: a Randomized, Double-blind Controlled, Parallel-group Designed Trial. Journal of oleo science. vol 65. issue 7. 2017-03-01. PMID:27321122. |
a randomized, double-blind controlled, parallel-group designed trial was performed to investigate the effect of alpha linolenic acid (ala)-enriched diacylglycerol (dag) on visceral fat area (vfa) in obese subjects. |
2017-03-01 |
2023-08-13 |
human |