Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
K Yutani, S Hayashi, Y Sugisaki, K Ogasahar. Role of conserved proline residues in stabilizing tryptophan synthase alpha subunit: analysis by mutants with alanine or glycine. Proteins. vol 9. issue 2. 1991-04-26. PMID:2008436. |
the far-ultraviolet (uv) cd spectra of five mutant alpha subunits with ala in place of pro were identical to the spectrum of the wild-type protein, the exception being the mutant at position 207 (p207a). |
1991-04-26 |
2023-08-11 |
Not clear |
M Harkness, D R Harkness, F Kutlar, A Kutlar, J B Wilson, B B Webber, J F Codrington, T H Huisma. Hb Sun Prairie or alpha(2)130(H13)Ala----Pro beta 2, a new unstable variant occurring in low quantities. Hemoglobin. vol 14. issue 5. 1991-04-26. PMID:2079430. |
hb sun prairie or alpha(2)130(h13)ala----pro beta 2, a new unstable variant occurring in low quantities. |
1991-04-26 |
2023-08-11 |
Not clear |
M Harkness, D R Harkness, F Kutlar, A Kutlar, J B Wilson, B B Webber, J F Codrington, T H Huisma. Hb Sun Prairie or alpha(2)130(H13)Ala----Pro beta 2, a new unstable variant occurring in low quantities. Hemoglobin. vol 14. issue 5. 1991-04-26. PMID:2079430. |
structural analyses identified an ala----pro replacement at position 130 of the alpha chain. |
1991-04-26 |
2023-08-11 |
Not clear |
M Harkness, D R Harkness, F Kutlar, A Kutlar, J B Wilson, B B Webber, J F Codrington, T H Huisma. Hb Sun Prairie or alpha(2)130(H13)Ala----Pro beta 2, a new unstable variant occurring in low quantities. Hemoglobin. vol 14. issue 5. 1991-04-26. PMID:2079430. |
gene mapping failed to detect an alpha-thalassemia deletion (alpha alpha/alpha alpha), while dot-blot analysis of amplified dna with synthetic probes localized a g----c mutation in codon 130 (resulting in the ala----pro mutation) of the alpha 2-globin genes of both chromosomes. |
1991-04-26 |
2023-08-11 |
Not clear |
D Plaseska, L H Gu, J B Wilson, J F Codrington, T H Huisman, S Das. Hb Sun Prairie or alpha(2)130(H13)Ala----Pro beta 2; second observation in an Indian adult. Hemoglobin. vol 14. issue 5. 1991-04-26. PMID:2079431. |
hb sun prairie or alpha(2)130(h13)ala----pro beta 2; second observation in an indian adult. |
1991-04-26 |
2023-08-11 |
Not clear |
Y Ohba, K Fujisawa, K Imai, W Leowattana, Y Tani, M Ami, T Miyaj. A new alpha chain variant Hb Tonosho [alpha 110(G17)Ala----Thr]: subunit dissociation during cation exchange chromatography for Hb A1c assay. Hemoglobin. vol 14. issue 4. 1991-03-18. PMID:2283295. |
a new alpha chain variant hb tonosho [alpha 110(g17)ala----thr]: subunit dissociation during cation exchange chromatography for hb a1c assay. |
1991-03-18 |
2023-08-11 |
Not clear |
Y Ohba, K Fujisawa, K Imai, W Leowattana, Y Tani, M Ami, T Miyaj. A new alpha chain variant Hb Tonosho [alpha 110(G17)Ala----Thr]: subunit dissociation during cation exchange chromatography for Hb A1c assay. Hemoglobin. vol 14. issue 4. 1991-03-18. PMID:2283295. |
a new alpha chain variant, alpha 110(g17)ala----thr, was detected because of subunit dissociation during the determination of the hb a1c by automated cation exchange high performance liquid chromatography. |
1991-03-18 |
2023-08-11 |
Not clear |
D Plaseska, P A de Alarcon, S McMillan, M Walbrecht, J B Wilson, T H Huisma. Hb Iowa or alpha 2 beta 2(119)(GH2)Gly----Ala. Hemoglobin. vol 14. issue 4. 1991-03-18. PMID:2283296. |
hb iowa or alpha 2 beta 2(119)(gh2)gly----ala. hb iowa with a gly----ala mutation at position beta 119(gh2) was observed in a black infant and her mother. |
1991-03-18 |
2023-08-11 |
Not clear |
M C Perry, C Head, V F Fairbanks, R T Jones, H Taylor, V Prou. Hemoglobin Columbia Missouri or alpha 2[88 (F9) Ala----Val]beta 2: a new high-oxygen-affinity hemoglobin that causes erythrocytosis. Mayo Clinic proceedings. vol 66. issue 1. 1991-02-22. PMID:1988759. |
hemoglobin columbia missouri or alpha 2[88 (f9) ala----val]beta 2: a new high-oxygen-affinity hemoglobin that causes erythrocytosis. |
1991-02-22 |
2023-08-11 |
Not clear |
M C Perry, C Head, V F Fairbanks, R T Jones, H Taylor, V Prou. Hemoglobin Columbia Missouri or alpha 2[88 (F9) Ala----Val]beta 2: a new high-oxygen-affinity hemoglobin that causes erythrocytosis. Mayo Clinic proceedings. vol 66. issue 1. 1991-02-22. PMID:1988759. |
a previously undescribed hemoglobin variant, hemoglobin columbia missouri, alpha 88 (f9) ala----val, was detected in a 22-year-old white man who was undergoing assessment for erythrocytosis. |
1991-02-22 |
2023-08-11 |
Not clear |
H J Li, X N Zhao, F Qin, H W Li, L Li, X J He, X S Chang, Z M Li, K X Liang, F L Xin. Abnormal hemoglobins in the Silk Road region of China. Human genetics. vol 86. issue 2. 1991-02-12. PMID:2265836. |
two variants [hb tashikuergan or alpha 19(ab1)ala----glu; hb tianshui or beta 39(c5) gln----arg] were observed for the first time. |
1991-02-12 |
2023-08-11 |
Not clear |
S J Tzartos, M S Remoundo. Fine localization of the major alpha-bungarotoxin binding site to residues alpha 189-195 of the Torpedo acetylcholine receptor. Residues 189, 190, and 195 are indispensable for binding. The Journal of biological chemistry. vol 265. issue 35. 1991-01-23. PMID:2254308. |
twenty-six analogs of the alpha 188-197, most having 1 residue substituted by ala or gly, showed that tyr189, tyr190, and especially asp195 were indispensable for 125i-alpha-bungarotoxin binding. |
1991-01-23 |
2023-08-11 |
human |
A M Spiegel, W F Simonds, T L Jones, P K Goldsmith, C G Unso. Antibodies as probes of G-protein receptor-effector coupling and of G-protein membrane attachment. Biochemical Society symposium. vol 56. 1991-01-22. PMID:2175191. |
a mutant alpha i 1 (second residue gly changed to ala) fails to incorporate myristate and is localized in the soluble fraction. |
1991-01-22 |
2023-08-11 |
human |
A P Warren, I Paschedag, C Benoist, J Peccoud, D Mathis, D B Thoma. Defects in antigen presentation of mutant influenza haemagglutinins are reversed by mutations in the MHC class II molecule. The EMBO journal. vol 9. issue 12. 1991-01-11. PMID:2123452. |
a t cell clone specific for ha1 120-139 failed to respond to a laboratory mutant virus (ha1 135 gly----arg) whereas optimal responses were observed with a mutant ak transfectant (ak alpha 56 arg----ala). |
1991-01-11 |
2023-08-11 |
Not clear |
A P Warren, I Paschedag, C Benoist, J Peccoud, D Mathis, D B Thoma. Defects in antigen presentation of mutant influenza haemagglutinins are reversed by mutations in the MHC class II molecule. The EMBO journal. vol 9. issue 12. 1991-01-11. PMID:2123452. |
similarly, mutant transfectant 62 (ak alpha 62 gly----ala) was able to present a natural variant virus a/tex/77 to a t cell clone specific for ha1 48-67. |
1991-01-11 |
2023-08-11 |
Not clear |
G G Cadd, M D Uhler, G S McKnigh. Holoenzymes of cAMP-dependent protein kinase containing the neural form of type I regulatory subunit have an increased sensitivity to cyclic nucleotides. The Journal of biological chemistry. vol 265. issue 32. 1991-01-08. PMID:2174040. |
two mutant forms of ri beta were constructed that converted the ri beta sequence to that of ri alpha at position 98 (ri beta ala) or positions 98 and 99 (ri beta ala/ile). |
1991-01-08 |
2023-08-11 |
mouse |
G G Cadd, M D Uhler, G S McKnigh. Holoenzymes of cAMP-dependent protein kinase containing the neural form of type I regulatory subunit have an increased sensitivity to cyclic nucleotides. The Journal of biological chemistry. vol 265. issue 32. 1991-01-08. PMID:2174040. |
holoenzymes containing ri beta ala and ri beta ala/ile gave ka values which were higher than wild type ri beta, with the double mutant shifting toward the ka value of ri alpha holoenzymes by about 30%. |
1991-01-08 |
2023-08-11 |
mouse |
P A Raj, S D Soni, N Ramasubbu, K K Bhandary, M J Levin. Crystal structure and solution conformation of S,S'-bis(Boc-Cys-Ala-OMe): intramolecular antiparallel beta-sheet conformation of an acyclic cystine peptide. Biopolymers. vol 30. issue 1-2. 1990-12-13. PMID:2224052. |
nuclear overhauser effects observed between cys c alpha h and ala nh protons and ir studies provide evidence of the occurrence of antiparallel beta-sheet structure in these solvents. |
1990-12-13 |
2023-08-11 |
Not clear |
P C Lyu, M I Liff, L A Marky, N R Kallenbac. Side chain contributions to the stability of alpha-helical structure in peptides. Science (New York, N.Y.). vol 250. issue 4981. 1990-12-04. PMID:2237416. |
this order differs from both host-guest copolymer values (met greater than ile greater than leu greater than ala greater than gln greater than val greater than thr greater than asn greater than ser greater than gly) and the tendencies of these amino acids to occur in helices in globular proteins (ala greater than met greater than leu greater than gln greater than ile greater than val greater than asn, thr greater than ser greater than gly), but matches the order found in a series of synthetic coiled-coil alpha helices, except for ser. |
1990-12-04 |
2023-08-11 |
Not clear |
L P McIntosh, A J Wand, D F Lowry, A G Redfield, F W Dahlquis. Assignment of the backbone 1H and 15N NMR resonances of bacteriophage T4 lysozyme. Biochemistry. vol 29. issue 27. 1990-11-16. PMID:2207079. |
the main-chain amide 1h-15n resonances and h alpha resonances were resolved and classified into 18 amino acid types by using hmqc and 15n-edited cosy measurements, respectively, of t4 lysozymes selectively enriched with one or more of alpha-15n-labeled ala, arg, asn, asp, gly, gln, glu, ile, leu, lys, met, phe, ser, thr, trp, tyr, or val. |
1990-11-16 |
2023-08-11 |
Not clear |